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The map label for this gene is trkH [H]

Identifier: 15603363

GI number: 15603363

Start: 1688181

End: 1689644

Strand: Direct

Name: trkH [H]

Synonym: PM1498

Alternate gene names: 15603363

Gene position: 1688181-1689644 (Clockwise)

Preceding gene: 15603362

Following gene: 15603364

Centisome position: 74.78

GC content: 38.05

Gene sequence:

>1464_bases
TTGAGAATATTATCCATTATCCGCATTGTTGGCATTCTTGTGATGTGTTTTTCCCTCACCATGTTAGCACCTGCTTTTGT
GGCATTACTCTATGGTGATGGAGGCGGTAAAGCGTTTATGCAGACTTTTGTAATGAGTGCTATTGTTGGTATGTTATTGT
GGTGGCCTTGTCATCACCATAAAGAAGAATTACGTTCTCGAGATGGCTTTTTAATTGTGGTGGCATTTTGGTTAGTACTC
GGCAGTATCGGGGCCATTCCATTCATGTTGTTTGAGAAACCGCACCTGTCTTTTTCCTCGGCAATTTTTGAGTCATTTTC
TGGCTTAACTACCACGGGTGCTACTGTCATCGAAGGTTTAGACCAACTTCCAAAAGCGATTTTATTTTATCGACAGTTAC
TCCAATGGCTAGGCGGGATGGGGATCATTGTATTAGCGGTAGCGATTATTCCTTTATTAGGTATAGGTGGTACACAGTTA
TATCGAGCAGAGTCCTCCGGTCCTTTAAAAGAACAAAAATTACGCCCACGTATTGCTGAAGTAGCAAAACTTCTGTGGAT
TTTATATTTCTCTCTCACGGTTCTTTGTGCAATAGCGTATTGGTTTGCTGGCATGAATGCATTTGATGCCATTGGACACA
GTTTTTCTACGGTAGCGAACGGTGGATTTTCAACCCATGATGCAAGTATGGGGTATTTCAATAATGCGACTATTTATTTG
ATTACAACCTTCTTTATGCTGATTGCGGGGGTTAATTTTAATTTGCATATTTCCGCGCTGACGTATCTCGGTAAACAAAG
TCTCTGGAAAAATTATTGGAAAGATCCTGAATTTCGTTTTTTCGTAGCAATACAAGTACTGTTTATTTTATTATTTTCTC
TCTCTTTATATTTTTATGACGTCCTCACAAATTTAAGTGATGCTTTTATTCAGGGTTCATTACAATTGACATCAATGTCA
ATGACCGCAGGTTATAGTATTTTTGATATGAATAACTTACCTGCATTTTCTGCTATGTTATTAGTCATTGCTAGTGTCAT
CGGCGGATGTGGTGGTTCAACAACAGGTGGCTTAAAAACTATCCGCGTTTTAATTTTATGGCTACAAGTTAAAAGAGAAT
TACGTAGTCTTGTCCACCCAAATTTAGTTCAACCAATAAAACTAGGACAAAATATTTTACCTATTCGGATGTTAGAAAGT
ATTTGGGCTTTTCTTATGATTTTTATTTTGGTGTATTGGGTCTGTGTTTTTGCCGTGATTCTTTGTGGTATGGATGTGTT
TGATGCTATGGGATCTGTTTTTGCAACATTAACCAATGCGGGTCCCGGGCTTGGTGTGATCCACCAAGATTTTCTTAATG
TCCCTGAAAGCGCCAAGATTGTTTTTGCATTTGCCATGATTTGTGGTCGTTTAGAAATTTTTTCTTTATTGGTTCTCTTT
ACTCCTACTTTTTGGAAAGAATAA

Upstream 100 bases:

>100_bases
AGCATTTGAGTTAGGGATCAGAGATGATAAACTGACAGCATTTGAACAAGCCTTAATTGAACGTTTTAGTGGACAGTTAC
AATTAGAAAGAGAGTAAATT

Downstream 100 bases:

>100_bases
TGAAAACACTGATTCTCTATTCAAGCCGTGATGGGCAAACGAAAAAAATCGCAGAATTTATTGCTTCTAAATTAAGTGGT
GATGTACAAACACAACCTTT

Product: TrkH

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MRILSIIRIVGILVMCFSLTMLAPAFVALLYGDGGGKAFMQTFVMSAIVGMLLWWPCHHHKEELRSRDGFLIVVAFWLVL
GSIGAIPFMLFEKPHLSFSSAIFESFSGLTTTGATVIEGLDQLPKAILFYRQLLQWLGGMGIIVLAVAIIPLLGIGGTQL
YRAESSGPLKEQKLRPRIAEVAKLLWILYFSLTVLCAIAYWFAGMNAFDAIGHSFSTVANGGFSTHDASMGYFNNATIYL
ITTFFMLIAGVNFNLHISALTYLGKQSLWKNYWKDPEFRFFVAIQVLFILLFSLSLYFYDVLTNLSDAFIQGSLQLTSMS
MTAGYSIFDMNNLPAFSAMLLVIASVIGGCGGSTTGGLKTIRVLILWLQVKRELRSLVHPNLVQPIKLGQNILPIRMLES
IWAFLMIFILVYWVCVFAVILCGMDVFDAMGSVFATLTNAGPGLGVIHQDFLNVPESAKIVFAFAMICGRLEIFSLLVLF
TPTFWKE

Sequences:

>Translated_487_residues
MRILSIIRIVGILVMCFSLTMLAPAFVALLYGDGGGKAFMQTFVMSAIVGMLLWWPCHHHKEELRSRDGFLIVVAFWLVL
GSIGAIPFMLFEKPHLSFSSAIFESFSGLTTTGATVIEGLDQLPKAILFYRQLLQWLGGMGIIVLAVAIIPLLGIGGTQL
YRAESSGPLKEQKLRPRIAEVAKLLWILYFSLTVLCAIAYWFAGMNAFDAIGHSFSTVANGGFSTHDASMGYFNNATIYL
ITTFFMLIAGVNFNLHISALTYLGKQSLWKNYWKDPEFRFFVAIQVLFILLFSLSLYFYDVLTNLSDAFIQGSLQLTSMS
MTAGYSIFDMNNLPAFSAMLLVIASVIGGCGGSTTGGLKTIRVLILWLQVKRELRSLVHPNLVQPIKLGQNILPIRMLES
IWAFLMIFILVYWVCVFAVILCGMDVFDAMGSVFATLTNAGPGLGVIHQDFLNVPESAKIVFAFAMICGRLEIFSLLVLF
TPTFWKE
>Mature_487_residues
MRILSIIRIVGILVMCFSLTMLAPAFVALLYGDGGGKAFMQTFVMSAIVGMLLWWPCHHHKEELRSRDGFLIVVAFWLVL
GSIGAIPFMLFEKPHLSFSSAIFESFSGLTTTGATVIEGLDQLPKAILFYRQLLQWLGGMGIIVLAVAIIPLLGIGGTQL
YRAESSGPLKEQKLRPRIAEVAKLLWILYFSLTVLCAIAYWFAGMNAFDAIGHSFSTVANGGFSTHDASMGYFNNATIYL
ITTFFMLIAGVNFNLHISALTYLGKQSLWKNYWKDPEFRFFVAIQVLFILLFSLSLYFYDVLTNLSDAFIQGSLQLTSMS
MTAGYSIFDMNNLPAFSAMLLVIASVIGGCGGSTTGGLKTIRVLILWLQVKRELRSLVHPNLVQPIKLGQNILPIRMLES
IWAFLMIFILVYWVCVFAVILCGMDVFDAMGSVFATLTNAGPGLGVIHQDFLNVPESAKIVFAFAMICGRLEIFSLLVLF
TPTFWKE

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=487, Percent_Identity=55.8521560574949, Blast_Score=503, Evalue=1e-143,
Organism=Escherichia coli, GI1787626, Length=484, Percent_Identity=38.6363636363636, Blast_Score=326, Evalue=2e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 54001; Mature: 54001

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHCCC
>Mature Secondary Structure
MRILSIIRIVGILVMCFSLTMLAPAFVALLYGDGGGKAFMQTFVMSAIVGMLLWWPCHHH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHH
KEELRSRDGFLIVVAFWLVLGSIGAIPFMLFEKPHLSFSSAIFESFSGLTTTGATVIEGL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHH
DQLPKAILFYRQLLQWLGGMGIIVLAVAIIPLLGIGGTQLYRAESSGPLKEQKLRPRIAE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHCHHHHH
VAKLLWILYFSLTVLCAIAYWFAGMNAFDAIGHSFSTVANGGFSTHDASMGYFNNATIYL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCHHHH
ITTFFMLIAGVNFNLHISALTYLGKQSLWKNYWKDPEFRFFVAIQVLFILLFSLSLYFYD
HHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VLTNLSDAFIQGSLQLTSMSMTAGYSIFDMNNLPAFSAMLLVIASVIGGCGGSTTGGLKT
HHHHHHHHHHHCCHHEEEEHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHH
IRVLILWLQVKRELRSLVHPNLVQPIKLGQNILPIRMLESIWAFLMIFILVYWVCVFAVI
HHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LCGMDVFDAMGSVFATLTNAGPGLGVIHQDFLNVPESAKIVFAFAMICGRLEIFSLLVLF
HHCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TPTFWKE
CCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]