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The map label for this gene is glpR [H]

Identifier: 15603304

GI number: 15603304

Start: 1624227

End: 1624985

Strand: Direct

Name: glpR [H]

Synonym: PM1439

Alternate gene names: 15603304

Gene position: 1624227-1624985 (Clockwise)

Preceding gene: 15603303

Following gene: 15603308

Centisome position: 71.95

GC content: 41.5

Gene sequence:

>759_bases
ATGAAACAATCTATTCGCCACCAAAAAATTCTTGATCTCGTTACGCAAAAAGGCTACGTCAGTACAGAAGAGCTGGTTAG
CCTCTTAGATGTCAGTCCCCCGACTATTCGCCGTGATTTAAATGAACTGGCTGAGAAAAATTTAATTCGTCGTCATCATG
GTGGTGCTGCCTCGCCCTCTACGGCAGAAAACAGTGATTATGAAGATCGGAAAAACTTCTTCTTGAAAGGGAAAAACTGT
ATTGCTCAGCGAGTTGCCAGCTTAATTCCAAACGGTGCTTCCTTGTTTATTGATATTGGTACCACACCAGAAGCGGTAGC
GAAGGCACTCTTAAATCATCAAAAATTACGCATTGTGACCAATAACATTAATGCCGCTTATATCCTAATGCAAAATGAAA
CCTTTGATATTATTTTGGCGAGTGGTTCATTACGTCAAGACGGGGGGATTATTGGTGAGGCAACCGTTGCCTTTATTTCA
CAATTCCGTTTAGATTTTGGTATTTTAGGTATCAGTGGTATTGACTTAGATGGCTCACTGTTAGACTACGACTACCATGA
AGTACAGGTCAAACGCGCCATTATCGAAAGTTCTCGCCAAACCTTATTAGTGACGGATCACTCAAAATTCTCACGACGTG
CCATGGTGCGTTTAGGCTCTATTGCGGACATTGAGCAGGTCTTTACTGATCAAATGCCACCTGAGCCGATCTTAGAAATC
TTAAAAGCAAACCACGTCAAATTACATATTTGCCAATAA

Upstream 100 bases:

>100_bases
TGCTCGGTTGGGCAACGATAAAGCCCACACTAAAAAGATGATCAGCAAATAAAAATAGCATAAAATGCAATCAAAACTAG
CCACAACATGAAGGCATTAC

Downstream 100 bases:

>100_bases
AAAAAGGGGGACAATGTCCCCCCAAAAGCGCTCTGCATGAGCGCATAGTTCCTATTTGTTCGCATCTAATGCCATAGCTA
ATAAACTGATTGGATGTAAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MKQSIRHQKILDLVTQKGYVSTEELVSLLDVSPPTIRRDLNELAEKNLIRRHHGGAASPSTAENSDYEDRKNFFLKGKNC
IAQRVASLIPNGASLFIDIGTTPEAVAKALLNHQKLRIVTNNINAAYILMQNETFDIILASGSLRQDGGIIGEATVAFIS
QFRLDFGILGISGIDLDGSLLDYDYHEVQVKRAIIESSRQTLLVTDHSKFSRRAMVRLGSIADIEQVFTDQMPPEPILEI
LKANHVKLHICQ

Sequences:

>Translated_252_residues
MKQSIRHQKILDLVTQKGYVSTEELVSLLDVSPPTIRRDLNELAEKNLIRRHHGGAASPSTAENSDYEDRKNFFLKGKNC
IAQRVASLIPNGASLFIDIGTTPEAVAKALLNHQKLRIVTNNINAAYILMQNETFDIILASGSLRQDGGIIGEATVAFIS
QFRLDFGILGISGIDLDGSLLDYDYHEVQVKRAIIESSRQTLLVTDHSKFSRRAMVRLGSIADIEQVFTDQMPPEPILEI
LKANHVKLHICQ
>Mature_252_residues
MKQSIRHQKILDLVTQKGYVSTEELVSLLDVSPPTIRRDLNELAEKNLIRRHHGGAASPSTAENSDYEDRKNFFLKGKNC
IAQRVASLIPNGASLFIDIGTTPEAVAKALLNHQKLRIVTNNINAAYILMQNETFDIILASGSLRQDGGIIGEATVAFIS
QFRLDFGILGISGIDLDGSLLDYDYHEVQVKRAIIESSRQTLLVTDHSKFSRRAMVRLGSIADIEQVFTDQMPPEPILEI
LKANHVKLHICQ

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=252, Percent_Identity=64.6825396825397, Blast_Score=330, Evalue=6e-92,
Organism=Escherichia coli, GI87082344, Length=248, Percent_Identity=39.9193548387097, Blast_Score=213, Evalue=1e-56,
Organism=Escherichia coli, GI226510968, Length=232, Percent_Identity=31.8965517241379, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1788069, Length=246, Percent_Identity=27.6422764227642, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789519, Length=249, Percent_Identity=27.3092369477912, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1789170, Length=234, Percent_Identity=29.0598290598291, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787540, Length=248, Percent_Identity=28.2258064516129, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789059, Length=235, Percent_Identity=26.3829787234043, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790753, Length=239, Percent_Identity=23.8493723849372, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787063, Length=231, Percent_Identity=24.2424242424242, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1790635, Length=264, Percent_Identity=23.1060606060606, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28030; Mature: 28030

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQSIRHQKILDLVTQKGYVSTEELVSLLDVSPPTIRRDLNELAEKNLIRRHHGGAASPS
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
TAENSDYEDRKNFFLKGKNCIAQRVASLIPNGASLFIDIGTTPEAVAKALLNHQKLRIVT
CCCCCCCCHHHHHEECCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCEEEEEE
NNINAAYILMQNETFDIILASGSLRQDGGIIGEATVAFISQFRLDFGILGISGIDLDGSL
ECCCEEEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCE
LDYDYHEVQVKRAIIESSRQTLLVTDHSKFSRRAMVRLGSIADIEQVFTDQMPPEPILEI
ECCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHH
LKANHVKLHICQ
HHCCCEEEEEEC
>Mature Secondary Structure
MKQSIRHQKILDLVTQKGYVSTEELVSLLDVSPPTIRRDLNELAEKNLIRRHHGGAASPS
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
TAENSDYEDRKNFFLKGKNCIAQRVASLIPNGASLFIDIGTTPEAVAKALLNHQKLRIVT
CCCCCCCCHHHHHEECCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCEEEEEE
NNINAAYILMQNETFDIILASGSLRQDGGIIGEATVAFISQFRLDFGILGISGIDLDGSL
ECCCEEEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCE
LDYDYHEVQVKRAIIESSRQTLLVTDHSKFSRRAMVRLGSIADIEQVFTDQMPPEPILEI
ECCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHH
LKANHVKLHICQ
HHCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]