Click here to switch to the map view.

The map label for this gene is glpG [H]

Identifier: 15603303

GI number: 15603303

Start: 1623292

End: 1624167

Strand: Direct

Name: glpG [H]

Synonym: PM1438

Alternate gene names: 15603303

Gene position: 1623292-1624167 (Clockwise)

Preceding gene: 15603301

Following gene: 15603304

Centisome position: 71.91

GC content: 42.58

Gene sequence:

>876_bases
ATGCGATATTTATTTGGTAGTGAAATCCCCACATTGGCTTTTCGTTTTCGTGATTATATTCGTGCACAATTTAACGTGGA
AGTGGAACTGCGCGAGATACAAGACGAAAACGGTCAACAAATTCAACTTTTTTTACCTCAACATGCACCGCACTTTGAGG
CTATCCTTGCGGAAGTACCGCTTTTTCTCGCAGACCCTTTTCATACCAAATATGAACAGGCAAGTTGGCAACGTGGAGAT
ACGCAGTCAACCACGACCTCACTAAAAGGAATGTTGCAGCAATCTGGACTCACCCTCAGTGCATTACGTAGCCGATCGCG
TACAGGTCCTTTCACCCTTTTTATTACTACGCTCTGCCTTGTGATCTATATTTTCCAGCTGACAGGCTATCAAGACAGTA
TTCTCACCTTGATGCATTATCCTGAGAATACACAGCAAGATACACAATTTTGGCGTTATTTATCACATACTTTCGTGCAT
CTTTCTCCCCTGCATATTCTGTTTAATTTGTTATGGTGGTGGTTGTTTGGTCATACAATTGAACACCATTTTGGTACAGG
AAAATTATTTCAGCTCTTCTTAATCGCCGGTTTACTTAGTGGTTTTGCGCAAAATATTGCCTCCGGACCTTACTTTTTTG
GCTTATCTGGCGTGGTATATGCCGTCTTAGGCTATGTGTTAATTTATGATAAGTGGGGGAAAAACGCGGACTTCACTCTC
CCTAGCGGGTTTTCCTTAATGCTGATTGTCGGGATTGTCAGTGGATTTATCAGCCCACTCTTTGGAGTTGAAATGGGTAA
TACAGCCCACATTACTGGCTTAATTGTCGGCTTACTGCTCGGTTGGGCAACGATAAAGCCCACACTAAAAAGATGA

Upstream 100 bases:

>100_bases
AACTAAACCCACTAAATCCTTTTGGCTTATTTTCTCTTTCCATTCTTTACTCCATCTCGTTACAATAATGACATCTCAAT
ACAGCTATGGAATATAACAA

Downstream 100 bases:

>100_bases
TCAGCAAATAAAAATAGCATAAAATGCAATCAAAACTAGCCACAACATGAAGGCATTACATGAAACAATCTATTCGCCAC
CAAAAAATTCTTGATCTCGT

Product: hypothetical protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MRYLFGSEIPTLAFRFRDYIRAQFNVEVELREIQDENGQQIQLFLPQHAPHFEAILAEVPLFLADPFHTKYEQASWQRGD
TQSTTTSLKGMLQQSGLTLSALRSRSRTGPFTLFITTLCLVIYIFQLTGYQDSILTLMHYPENTQQDTQFWRYLSHTFVH
LSPLHILFNLLWWWLFGHTIEHHFGTGKLFQLFLIAGLLSGFAQNIASGPYFFGLSGVVYAVLGYVLIYDKWGKNADFTL
PSGFSLMLIVGIVSGFISPLFGVEMGNTAHITGLIVGLLLGWATIKPTLKR

Sequences:

>Translated_291_residues
MRYLFGSEIPTLAFRFRDYIRAQFNVEVELREIQDENGQQIQLFLPQHAPHFEAILAEVPLFLADPFHTKYEQASWQRGD
TQSTTTSLKGMLQQSGLTLSALRSRSRTGPFTLFITTLCLVIYIFQLTGYQDSILTLMHYPENTQQDTQFWRYLSHTFVH
LSPLHILFNLLWWWLFGHTIEHHFGTGKLFQLFLIAGLLSGFAQNIASGPYFFGLSGVVYAVLGYVLIYDKWGKNADFTL
PSGFSLMLIVGIVSGFISPLFGVEMGNTAHITGLIVGLLLGWATIKPTLKR
>Mature_291_residues
MRYLFGSEIPTLAFRFRDYIRAQFNVEVELREIQDENGQQIQLFLPQHAPHFEAILAEVPLFLADPFHTKYEQASWQRGD
TQSTTTSLKGMLQQSGLTLSALRSRSRTGPFTLFITTLCLVIYIFQLTGYQDSILTLMHYPENTQQDTQFWRYLSHTFVH
LSPLHILFNLLWWWLFGHTIEHHFGTGKLFQLFLIAGLLSGFAQNIASGPYFFGLSGVVYAVLGYVLIYDKWGKNADFTL
PSGFSLMLIVGIVSGFISPLFGVEMGNTAHITGLIVGLLLGWATIKPTLKR

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S54 family [H]

Homologues:

Organism=Escherichia coli, GI48994938, Length=283, Percent_Identity=37.8091872791519, Blast_Score=166, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022732
- InterPro:   IPR002610
- InterPro:   IPR022764 [H]

Pfam domain/function: PF12122 DUF3582; PF01694 Rhomboid [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 33094; Mature: 33094

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYLFGSEIPTLAFRFRDYIRAQFNVEVELREIQDENGQQIQLFLPQHAPHFEAILAEVP
CCCCCCCCCHHHHHHHHHHHHHHHCEEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHCC
LFLADPFHTKYEQASWQRGDTQSTTTSLKGMLQQSGLTLSALRSRSRTGPFTLFITTLCL
HHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHH
VIYIFQLTGYQDSILTLMHYPENTQQDTQFWRYLSHTFVHLSPLHILFNLLWWWLFGHTI
HHHHHHHCCCCHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHHFGTGKLFQLFLIAGLLSGFAQNIASGPYFFGLSGVVYAVLGYVLIYDKWGKNADFTL
HHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PSGFSLMLIVGIVSGFISPLFGVEMGNTAHITGLIVGLLLGWATIKPTLKR
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure
MRYLFGSEIPTLAFRFRDYIRAQFNVEVELREIQDENGQQIQLFLPQHAPHFEAILAEVP
CCCCCCCCCHHHHHHHHHHHHHHHCEEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHCC
LFLADPFHTKYEQASWQRGDTQSTTTSLKGMLQQSGLTLSALRSRSRTGPFTLFITTLCL
HHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHH
VIYIFQLTGYQDSILTLMHYPENTQQDTQFWRYLSHTFVHLSPLHILFNLLWWWLFGHTI
HHHHHHHCCCCHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHHFGTGKLFQLFLIAGLLSGFAQNIASGPYFFGLSGVVYAVLGYVLIYDKWGKNADFTL
HHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PSGFSLMLIVGIVSGFISPLFGVEMGNTAHITGLIVGLLLGWATIKPTLKR
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]