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The map label for this gene is speE [H]

Identifier: 15603246

GI number: 15603246

Start: 1575615

End: 1576535

Strand: Reverse

Name: speE [H]

Synonym: PM1381

Alternate gene names: 15603246

Gene position: 1576535-1575615 (Counterclockwise)

Preceding gene: 15603247

Following gene: 15603244

Centisome position: 69.84

GC content: 43.21

Gene sequence:

>921_bases
ATGTACAATACGTTAAACAATAAAGAAGATATTTCATTAGTTTCAAATAATTTTGGTTTTCTACGCTTGCCTGTTCACTT
TAATCCCGTCGAAACGGATGCAGAGTGGGTTATTACTGGCGTACCGTTTGATGCGTCAGTATCGGGTCGCGCAGGAACGC
GTTTTGGTGCGGAAGCCATTCGTCGCGCGTCGGTGAATTTGGCTTGGGAACACTGTCGCTTTCCATGGGATTTTGATGTG
CGTGAGCGTTTAAAGATCGTGGATTGTGGCGATTTGGTTTATTCATTCGGTGATAATCAAAATTTCGTAGAAGAATTAGA
AGCGCACGCAACCGCTTTATTAAAAGCGGGTAAGCGTTGCTTAACTTTTGGTGGCGATCATTTCATTACCTTGCCTTTAT
TACGTGCCCATGCAAAACATTTTGGTAAGTTGGCGATGATTCACTTTGATGCCCATACGGATACCTATGAAAATGGCAGT
CGTTATGATCACGGTACCATGTTTTACCATGCGCCAAACGAAGGGTTAATTGATGCAGCCCATTCGGTACAAATTGGTAT
TCGTACTGAATTTGATCGCAACTTACCATTTACGGTACTTTCTGCGCCACAAGTCAACGAGGAGAGCGTGGCACAAACTG
TTGCTAAAATCAAAGAGGTAATTGGTGATTTACCTGTCTATTTAACCTTTGATATCGATTGTTTAGATCCTGCTTATGCA
CCGGGTACCGGTACGCCAGTCTGTGGTGGATTAAGCACAGACAGAGCATTGAAAATTTTACGTGCCTTGAAAGATGTGAA
TATTGTGGGTATGGATTTGGTTGAAGTCTCTCCTGCCTATGATCAATCGGACATTACTGCTTTAGCAGGTGCGACGTTGG
CGCTAGAAATGCTGTATATGCAAGGGGCGAAAAAAGGCTAA

Upstream 100 bases:

>100_bases
GTGGGCTTGAATGGTTATACCTATTTAGAAGACGAGTAATTGGCAAAAGTGCGGTCTATTTTCTGTAAAAAGACCGCGCT
TTAGGACAACAGGAATCACT

Downstream 100 bases:

>100_bases
TATTCCTTTTTCTTGAGCAAGAAAAATCCACTTTTGTTAAGAAAGTGGATTTTTTTATGCTTGATAACTCAAAGTGCGGT
GAGTTTCTGCTGCAATTCTA

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MYNTLNNKEDISLVSNNFGFLRLPVHFNPVETDAEWVITGVPFDASVSGRAGTRFGAEAIRRASVNLAWEHCRFPWDFDV
RERLKIVDCGDLVYSFGDNQNFVEELEAHATALLKAGKRCLTFGGDHFITLPLLRAHAKHFGKLAMIHFDAHTDTYENGS
RYDHGTMFYHAPNEGLIDAAHSVQIGIRTEFDRNLPFTVLSAPQVNEESVAQTVAKIKEVIGDLPVYLTFDIDCLDPAYA
PGTGTPVCGGLSTDRALKILRALKDVNIVGMDLVEVSPAYDQSDITALAGATLALEMLYMQGAKKG

Sequences:

>Translated_306_residues
MYNTLNNKEDISLVSNNFGFLRLPVHFNPVETDAEWVITGVPFDASVSGRAGTRFGAEAIRRASVNLAWEHCRFPWDFDV
RERLKIVDCGDLVYSFGDNQNFVEELEAHATALLKAGKRCLTFGGDHFITLPLLRAHAKHFGKLAMIHFDAHTDTYENGS
RYDHGTMFYHAPNEGLIDAAHSVQIGIRTEFDRNLPFTVLSAPQVNEESVAQTVAKIKEVIGDLPVYLTFDIDCLDPAYA
PGTGTPVCGGLSTDRALKILRALKDVNIVGMDLVEVSPAYDQSDITALAGATLALEMLYMQGAKKG
>Mature_306_residues
MYNTLNNKEDISLVSNNFGFLRLPVHFNPVETDAEWVITGVPFDASVSGRAGTRFGAEAIRRASVNLAWEHCRFPWDFDV
RERLKIVDCGDLVYSFGDNQNFVEELEAHATALLKAGKRCLTFGGDHFITLPLLRAHAKHFGKLAMIHFDAHTDTYENGS
RYDHGTMFYHAPNEGLIDAAHSVQIGIRTEFDRNLPFTVLSAPQVNEESVAQTVAKIKEVIGDLPVYLTFDIDCLDPAYA
PGTGTPVCGGLSTDRALKILRALKDVNIVGMDLVEVSPAYDQSDITALAGATLALEMLYMQGAKKG

Specific function: Catalyzes the formation of putrescine from agmatine [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=292, Percent_Identity=39.3835616438356, Blast_Score=197, Evalue=7e-51,
Organism=Homo sapiens, GI4502215, Length=296, Percent_Identity=26.3513513513513, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI10947139, Length=325, Percent_Identity=25.5384615384615, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1789306, Length=304, Percent_Identity=71.3815789473684, Blast_Score=453, Evalue=1e-129,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 33709; Mature: 33709

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNTLNNKEDISLVSNNFGFLRLPVHFNPVETDAEWVITGVPFDASVSGRAGTRFGAEAI
CCCCCCCCCCEEEEECCCCEEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHH
RRASVNLAWEHCRFPWDFDVRERLKIVDCGDLVYSFGDNQNFVEELEAHATALLKAGKRC
HHHHCEEEHHHCCCCCCCCHHHCEEEEEHHHHHEECCCCHHHHHHHHHHHHHHHHCCCEE
LTFGGDHFITLPLLRAHAKHFGKLAMIHFDAHTDTYENGSRYDHGTMFYHAPNEGLIDAA
EEECCCCEEEHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCEECC
HSVQIGIRTEFDRNLPFTVLSAPQVNEESVAQTVAKIKEVIGDLPVYLTFDIDCLDPAYA
CEEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCC
PGTGTPVCGGLSTDRALKILRALKDVNIVGMDLVEVSPAYDQSDITALAGATLALEMLYM
CCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
QGAKKG
HCCCCC
>Mature Secondary Structure
MYNTLNNKEDISLVSNNFGFLRLPVHFNPVETDAEWVITGVPFDASVSGRAGTRFGAEAI
CCCCCCCCCCEEEEECCCCEEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHH
RRASVNLAWEHCRFPWDFDVRERLKIVDCGDLVYSFGDNQNFVEELEAHATALLKAGKRC
HHHHCEEEHHHCCCCCCCCHHHCEEEEEHHHHHEECCCCHHHHHHHHHHHHHHHHCCCEE
LTFGGDHFITLPLLRAHAKHFGKLAMIHFDAHTDTYENGSRYDHGTMFYHAPNEGLIDAA
EEECCCCEEEHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCEECC
HSVQIGIRTEFDRNLPFTVLSAPQVNEESVAQTVAKIKEVIGDLPVYLTFDIDCLDPAYA
CEEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCC
PGTGTPVCGGLSTDRALKILRALKDVNIVGMDLVEVSPAYDQSDITALAGATLALEMLYM
CCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
QGAKKG
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA