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The map label for this gene is oxyR [H]

Identifier: 15603211

GI number: 15603211

Start: 1538561

End: 1539457

Strand: Reverse

Name: oxyR [H]

Synonym: PM1346

Alternate gene names: 15603211

Gene position: 1539457-1538561 (Counterclockwise)

Preceding gene: 15603213

Following gene: 15603210

Centisome position: 68.19

GC content: 42.81

Gene sequence:

>897_bases
ATGAATATCCGCGACTTAGAATATCTCGTGGCGCTTGCGGAGCACAAACATTTTCGCCGTGCCGCCGATGCATGTCATGT
CAGCCAACCCACATTAAGTGGTCAAATTCGCAAATTAGAAGATGAATTAGGGATTATTTTATTAGAACGCACTAGCCGCA
AAGTGTTATTCACTCAATCAGGCTTACTCCTTGTCGATCAAGCAAAAAACGTCTTAAAAGAAGTCAAATTACTTAAAGAA
ATGGCAAGTAACCAAGGTAAAGATATGACGGGTCCTATACATATTGGCGTCATTCCCACAGTGGGACCTTACCTACTTCC
TTATATCATGCCGGTACTCAAAGAAACCTTTCCTGATTTAGAACTTTTCTTATATGAAGCGCAAACTAATCAATTATTAG
AACAATTAGAAACTGGTCACTTAGATTGTGCCATCGTCGCCTCCGTACGCGAAACAGAAGCTTTTATCGAGGTCCCTATC
TTTCATGAAGCCATGCTATTAGCTGTCAGTGAAAATCACCCTTGGGCGAATGAGCGTACTATTGCAATGAATAGATTAAA
TGGCTGTGAAATGTTAATGCTCGATGACGGGCACTGCTTGCGCGATCAAACGATCGGCTACTGCTTCAGTGCAGGAGCAA
AAGAAAATGCGCATTTCCAAGCCACTAGTTTAGAAACGTTGCGCAACATGGTTGCCTCGAATACCGGCATAACATTGATG
CCTAAACTCGCAGTGATCAATGAAGGAAATCGTACAGGGGTCAAATATATTCCTTGTCACTCACCCGCCCCTTCTCGTGC
AATCACATTAGTTTATCGCCCGGGTTCTCCGTTACGAAATCGCTACGAGAAAATTGCACAGACCATTAGTCATTCAGTAC
AAGACGTATTGGACTAA

Upstream 100 bases:

>100_bases
AATCTATCTTACTCCTTTATGAATTCTAGTCAAATTTATGATATAGTTCTAAGCAATTGATTTAAAAATTTTAATTGTTT
CTATCAATAACGAGGTCAAA

Downstream 100 bases:

>100_bases
TTCTGAAGTCAGGAAAATATCAATATGGGTGTGAGAGCATTACAAAAAGAAAAAACCCGTCGCGCATTAATTGATGCCGC
TTTTAATCAGCTGACCGCGG

Product: DNA-binding transcriptional regulator OxyR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MNIRDLEYLVALAEHKHFRRAADACHVSQPTLSGQIRKLEDELGIILLERTSRKVLFTQSGLLLVDQAKNVLKEVKLLKE
MASNQGKDMTGPIHIGVIPTVGPYLLPYIMPVLKETFPDLELFLYEAQTNQLLEQLETGHLDCAIVASVRETEAFIEVPI
FHEAMLLAVSENHPWANERTIAMNRLNGCEMLMLDDGHCLRDQTIGYCFSAGAKENAHFQATSLETLRNMVASNTGITLM
PKLAVINEGNRTGVKYIPCHSPAPSRAITLVYRPGSPLRNRYEKIAQTISHSVQDVLD

Sequences:

>Translated_298_residues
MNIRDLEYLVALAEHKHFRRAADACHVSQPTLSGQIRKLEDELGIILLERTSRKVLFTQSGLLLVDQAKNVLKEVKLLKE
MASNQGKDMTGPIHIGVIPTVGPYLLPYIMPVLKETFPDLELFLYEAQTNQLLEQLETGHLDCAIVASVRETEAFIEVPI
FHEAMLLAVSENHPWANERTIAMNRLNGCEMLMLDDGHCLRDQTIGYCFSAGAKENAHFQATSLETLRNMVASNTGITLM
PKLAVINEGNRTGVKYIPCHSPAPSRAITLVYRPGSPLRNRYEKIAQTISHSVQDVLD
>Mature_298_residues
MNIRDLEYLVALAEHKHFRRAADACHVSQPTLSGQIRKLEDELGIILLERTSRKVLFTQSGLLLVDQAKNVLKEVKLLKE
MASNQGKDMTGPIHIGVIPTVGPYLLPYIMPVLKETFPDLELFLYEAQTNQLLEQLETGHLDCAIVASVRETEAFIEVPI
FHEAMLLAVSENHPWANERTIAMNRLNGCEMLMLDDGHCLRDQTIGYCFSAGAKENAHFQATSLETLRNMVASNTGITLM
PKLAVINEGNRTGVKYIPCHSPAPSRAITLVYRPGSPLRNRYEKIAQTISHSVQDVLD

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=289, Percent_Identity=70.9342560553633, Blast_Score=445, Evalue=1e-126,
Organism=Escherichia coli, GI157672245, Length=276, Percent_Identity=29.3478260869565, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1788887, Length=280, Percent_Identity=28.5714285714286, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787530, Length=302, Percent_Identity=24.1721854304636, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI145693105, Length=283, Percent_Identity=24.3816254416961, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1788748, Length=297, Percent_Identity=25.2525252525253, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1787879, Length=268, Percent_Identity=26.865671641791, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790208, Length=251, Percent_Identity=29.0836653386454, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788297, Length=254, Percent_Identity=27.1653543307087, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI2367136, Length=268, Percent_Identity=25.7462686567164, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1788296, Length=243, Percent_Identity=23.8683127572016, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI145693193, Length=308, Percent_Identity=24.025974025974, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787601, Length=145, Percent_Identity=26.2068965517241, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789506, Length=156, Percent_Identity=26.2820512820513, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87082132, Length=250, Percent_Identity=21.6, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788626, Length=295, Percent_Identity=23.728813559322, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33313; Mature: 33313

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIRDLEYLVALAEHKHFRRAADACHVSQPTLSGQIRKLEDELGIILLERTSRKVLFTQS
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCEEEEECCCCEEEEECC
GLLLVDQAKNVLKEVKLLKEMASNQGKDMTGPIHIGVIPTVGPYLLPYIMPVLKETFPDL
CEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCE
ELFLYEAQTNQLLEQLETGHLDCAIVASVRETEAFIEVPIFHEAMLLAVSENHPWANERT
EEEEEEHHHHHHHHHHHCCCCCEEEEEHHHHCHHEEECCCHHCEEEEEEECCCCCCCCCE
IAMNRLNGCEMLMLDDGHCLRDQTIGYCFSAGAKENAHFQATSLETLRNMVASNTGITLM
EEEECCCCCEEEEECCCCCCCCCHHHHHCCCCCCCCCCEEHHHHHHHHHHHHCCCCEEEE
PKLAVINEGNRTGVKYIPCHSPAPSRAITLVYRPGSPLRNRYEKIAQTISHSVQDVLD
EEEEEEECCCCCCCEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIRDLEYLVALAEHKHFRRAADACHVSQPTLSGQIRKLEDELGIILLERTSRKVLFTQS
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCEEEEECCCCEEEEECC
GLLLVDQAKNVLKEVKLLKEMASNQGKDMTGPIHIGVIPTVGPYLLPYIMPVLKETFPDL
CEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCE
ELFLYEAQTNQLLEQLETGHLDCAIVASVRETEAFIEVPIFHEAMLLAVSENHPWANERT
EEEEEEHHHHHHHHHHHCCCCCEEEEEHHHHCHHEEECCCHHCEEEEEEECCCCCCCCCE
IAMNRLNGCEMLMLDDGHCLRDQTIGYCFSAGAKENAHFQATSLETLRNMVASNTGITLM
EEEECCCCCEEEEECCCCCCCCCHHHHHCCCCCCCCCCEEHHHHHHHHHHHHCCCCEEEE
PKLAVINEGNRTGVKYIPCHSPAPSRAITLVYRPGSPLRNRYEKIAQTISHSVQDVLD
EEEEEEECCCCCCCEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 8890216 [H]