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The map label for this gene is corA

Identifier: 15603180

GI number: 15603180

Start: 1507861

End: 1508811

Strand: Reverse

Name: corA

Synonym: PM1315

Alternate gene names: 15603180

Gene position: 1508811-1507861 (Counterclockwise)

Preceding gene: 15603181

Following gene: 15603179

Centisome position: 66.84

GC content: 42.27

Gene sequence:

>951_bases
ATGATTAATGCTTTCGCTCTCGAAGATGCACGCCTTGTCCGCATTGATGAAAATACCAATGCAGAATTAAATTCCGCCAT
TTGGCTCGATCTCATCGAACCAAGTAGTGAAGAACGCGAAATTTTACAAGAAGGCTTAGGTCAGAGCCTTGCTACGTTCC
TTGAATTAGAAGATATCGAGGCATCGGCACGTTTCTTCGAAGATGAAGATGGTTTACACCTTCACTCTTTCTTTTATTGC
GAAGACGAAGAAGATTATGCCGACTTAGCCAGCGTGGCATTTACTGTGCGTGACGGTCGTCTTTTCACACTCCGTGATCG
TGAATTACCTGCTTTCCGTTTATATCGTATGCGCTCACGTAGTCAACGCTTGATTGAGTGTAATGCTTATGAAGTTTTAC
TTGATTTATTTGAAACCAAAATCGAGCAATTAGCCGACGTGATTGAAACCGTGTACTCAGATTTAGAAAAATTAAGTCGT
GTCATTTTAGATGGCACACAAGGGGAAGCCTTTGACCAAGCACTCTCCACCTTAACGGAACAAGAAGACACCAGTTCCAA
AGTACGTTTATGTTTAATGGATACGCAACGTGCGTTAAGTTTCTTAGTGCGTAAAACACGCTTACCAGCAAACCAGTTAG
AACAAGCGCGTGAAATCTTACGCGATATTGAATCTCTCCAACCTCACAACGAGTCACTGTTCCAACGTGTCAACTTTTTG
ATGCAAGCGGCAATGGGTTTCATCAGTATCGAACAAAACCGTATTATCAAGATCTTCTCGGTTGTGTCGGTGATTTTCCT
CCCGCCAACACTGGTTGCCTCTAACTATGGTATGAACTTTGATATTATGCCAGAATTAGGCTTTAAATTTGGTTATCCTA
TGGCGTTAGGCTTAATGGCACTGGCGGCATTTGCACCTTATTGGTATTTCAAACGCAAAGGCTGGTTATAA

Upstream 100 bases:

>100_bases
ATTTAACCGCACTTTTATCGTTGAATTCTTTTTAACAAGATTTCGTTTGATCGCTTTTGTTCATAGCGTTGTTCATAATC
CAATTAAGGAGTATGACAAA

Downstream 100 bases:

>100_bases
ATCTACAGGACGTTAATATGAATACATTACAATTACTCGTTTTTATCATTATTGATCTTTATGGTCTGATTTTAGTATTA
CGCGCGTGGTTCCAATTCAG

Product: magnesium/nickel/cobalt transporter CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MINAFALEDARLVRIDENTNAELNSAIWLDLIEPSSEEREILQEGLGQSLATFLELEDIEASARFFEDEDGLHLHSFFYC
EDEEDYADLASVAFTVRDGRLFTLRDRELPAFRLYRMRSRSQRLIECNAYEVLLDLFETKIEQLADVIETVYSDLEKLSR
VILDGTQGEAFDQALSTLTEQEDTSSKVRLCLMDTQRALSFLVRKTRLPANQLEQAREILRDIESLQPHNESLFQRVNFL
MQAAMGFISIEQNRIIKIFSVVSVIFLPPTLVASNYGMNFDIMPELGFKFGYPMALGLMALAAFAPYWYFKRKGWL

Sequences:

>Translated_316_residues
MINAFALEDARLVRIDENTNAELNSAIWLDLIEPSSEEREILQEGLGQSLATFLELEDIEASARFFEDEDGLHLHSFFYC
EDEEDYADLASVAFTVRDGRLFTLRDRELPAFRLYRMRSRSQRLIECNAYEVLLDLFETKIEQLADVIETVYSDLEKLSR
VILDGTQGEAFDQALSTLTEQEDTSSKVRLCLMDTQRALSFLVRKTRLPANQLEQAREILRDIESLQPHNESLFQRVNFL
MQAAMGFISIEQNRIIKIFSVVSVIFLPPTLVASNYGMNFDIMPELGFKFGYPMALGLMALAAFAPYWYFKRKGWL
>Mature_316_residues
MINAFALEDARLVRIDENTNAELNSAIWLDLIEPSSEEREILQEGLGQSLATFLELEDIEASARFFEDEDGLHLHSFFYC
EDEEDYADLASVAFTVRDGRLFTLRDRELPAFRLYRMRSRSQRLIECNAYEVLLDLFETKIEQLADVIETVYSDLEKLSR
VILDGTQGEAFDQALSTLTEQEDTSSKVRLCLMDTQRALSFLVRKTRLPANQLEQAREILRDIESLQPHNESLFQRVNFL
MQAAMGFISIEQNRIIKIFSVVSVIFLPPTLVASNYGMNFDIMPELGFKFGYPMALGLMALAAFAPYWYFKRKGWL

Specific function: Mediates influx of magnesium ions

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family

Homologues:

Organism=Escherichia coli, GI2367297, Length=316, Percent_Identity=72.4683544303797, Blast_Score=469, Evalue=1e-134,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CORA_PASMU (Q9CLC4)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246253.1
- ProteinModelPortal:   Q9CLC4
- GeneID:   1244662
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1315
- NMPDR:   fig|272843.1.peg.1316
- HOGENOM:   HBG350378
- OMA:   TQGFINI
- ProtClustDB:   PRK11085
- BioCyc:   PMUL272843:PM1315-MONOMER
- InterPro:   IPR004488
- InterPro:   IPR002523
- PANTHER:   PTHR21535:SF1
- TIGRFAMs:   TIGR00383

Pfam domain/function: PF01544 CorA

EC number: NA

Molecular weight: Translated: 36423; Mature: 36423

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe43bb38)-; HASH(0xe9e38c8)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINAFALEDARLVRIDENTNAELNSAIWLDLIEPSSEEREILQEGLGQSLATFLELEDIE
CCCCEEECCCEEEEECCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
ASARFFEDEDGLHLHSFFYCEDEEDYADLASVAFTVRDGRLFTLRDRELPAFRLYRMRSR
HHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHEEEECCEEEEEECCCCCHHHHHHHHHH
SQRLIECNAYEVLLDLFETKIEQLADVIETVYSDLEKLSRVILDGTQGEAFDQALSTLTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
QEDTSSKVRLCLMDTQRALSFLVRKTRLPANQLEQAREILRDIESLQPHNESLFQRVNFL
CCCCHHHEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
MQAAMGFISIEQNRIIKIFSVVSVIFLPPTLVASNYGMNFDIMPELGFKFGYPMALGLMA
HHHHHHHHEECCCHHHHHHHHHHHHHCCCHHHHCCCCCCEEECCCCCCCCCCHHHHHHHH
LAAFAPYWYFKRKGWL
HHHHHHHHHHHCCCCH
>Mature Secondary Structure
MINAFALEDARLVRIDENTNAELNSAIWLDLIEPSSEEREILQEGLGQSLATFLELEDIE
CCCCEEECCCEEEEECCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
ASARFFEDEDGLHLHSFFYCEDEEDYADLASVAFTVRDGRLFTLRDRELPAFRLYRMRSR
HHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHEEEECCEEEEEECCCCCHHHHHHHHHH
SQRLIECNAYEVLLDLFETKIEQLADVIETVYSDLEKLSRVILDGTQGEAFDQALSTLTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
QEDTSSKVRLCLMDTQRALSFLVRKTRLPANQLEQAREILRDIESLQPHNESLFQRVNFL
CCCCHHHEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
MQAAMGFISIEQNRIIKIFSVVSVIFLPPTLVASNYGMNFDIMPELGFKFGYPMALGLMA
HHHHHHHHEECCCHHHHHHHHHHHHHCCCHHHHCCCCCCEEECCCCCCCCCCHHHHHHHH
LAAFAPYWYFKRKGWL
HHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11248100