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The map label for this gene is lsrD [H]

Identifier: 15603141

GI number: 15603141

Start: 1469374

End: 1470375

Strand: Direct

Name: lsrD [H]

Synonym: PM1276

Alternate gene names: 15603141

Gene position: 1469374-1470375 (Clockwise)

Preceding gene: 15603140

Following gene: 15603142

Centisome position: 65.09

GC content: 41.42

Gene sequence:

>1002_bases
ATGTTTAACATGAAAAAATACAGTTGGGAAATCGCCCTATTTTGCTTAGTGATTATTGAAATTTTAGGCTTTGGTATGTT
TAATCCGCGCATGTTGGATCTCAATGTGCTGCTCTATAGTACCAGTGATTTTATTTATATCGGTATGCTTGCTTTACCGC
TGACCATGATTATTGTGTCAGGGGGGATGGATATTTCGTTTGGTTCAACAGTAGGGTTATGTGCGATCTTTTTGGGGGTG
TTGTTTAAATCGGATGTCCCGCTCAGCTTGGCGATTCCATTAACTTTCTTAGTAGGTATTTTATGTGGGGTAGTGAATGC
AAGTCTGATTCTTTATACCAAAGTCAACCCGTTAGTGATTACATTAGGAACCATGTATTTATTTGGGGGCGGGGCATTAT
TATTGTCTGGTTTTGCAGGTGCCACTGGTTATGAAGGCATCGGAGGTTTTCCTGAAAGCTTATTAGAATTTGCCAACCAA
ACCCTATTTGGTATTCCGACCCCGATTATCTACTTTTTATTGATGACGCTGGTCTTTTGGTTATTGATGCATAAAACCAC
TATTGGACGCAGTATTTTCTTAATTGGGCAGAGTGAACGGACTTCGCGTTATAGTGCCGTGCCGATCACAGGTACATTGT
ATATTATTTATTCAGCGATCGGTGTCGTGGCAGCGTTTGTGGGGATTTTGTTAGTGTCCTATTTTGGCTCTGCGCGTTCT
GATCTTGGCAGTTCTCTCTTAATGCCCGTCTTGACGGCGGTTGTACTGGGCGGCGCGAATATTTATGGTGGATCAGGTTC
TATCATTGGCACAGCAATTGCCGCACTTCTGATTGGGTATTTGCAACAAGGACTACAAATGGTCGGTGTTTCAAATGAAA
TATCCAGTGCATTATCAGGTGCGTTACTCATTATTGTTTTAATCGGAAAATCTATTAGTTTGCACTACGGTGCCATTGTG
CAATGGATTCATCGAAAAACGAAAAGCGAGTCAACTCATTAA

Upstream 100 bases:

>100_bases
GGACGTATTCGCGTGATGATTAACAATAATATTAAACTTCAGCGTTATGCCCGTTTCTTAAAAGACGATCAAGATGCGGT
GAAATAAGGGGAAGCAAAGG

Downstream 100 bases:

>100_bases
TGTTTCTATCCGAAGAAGGAGAATTAACTATGAAAAATCAATTAAAAGCTACCGCACTTGCCATTGCTGTTGGATTATCT
GCTTTAGGGACAGCGCAAGC

Product: hypothetical protein

Products: NA

Alternate protein names: AI-2 import system permease protein lsrD [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MFNMKKYSWEIALFCLVIIEILGFGMFNPRMLDLNVLLYSTSDFIYIGMLALPLTMIIVSGGMDISFGSTVGLCAIFLGV
LFKSDVPLSLAIPLTFLVGILCGVVNASLILYTKVNPLVITLGTMYLFGGGALLLSGFAGATGYEGIGGFPESLLEFANQ
TLFGIPTPIIYFLLMTLVFWLLMHKTTIGRSIFLIGQSERTSRYSAVPITGTLYIIYSAIGVVAAFVGILLVSYFGSARS
DLGSSLLMPVLTAVVLGGANIYGGSGSIIGTAIAALLIGYLQQGLQMVGVSNEISSALSGALLIIVLIGKSISLHYGAIV
QWIHRKTKSESTH

Sequences:

>Translated_333_residues
MFNMKKYSWEIALFCLVIIEILGFGMFNPRMLDLNVLLYSTSDFIYIGMLALPLTMIIVSGGMDISFGSTVGLCAIFLGV
LFKSDVPLSLAIPLTFLVGILCGVVNASLILYTKVNPLVITLGTMYLFGGGALLLSGFAGATGYEGIGGFPESLLEFANQ
TLFGIPTPIIYFLLMTLVFWLLMHKTTIGRSIFLIGQSERTSRYSAVPITGTLYIIYSAIGVVAAFVGILLVSYFGSARS
DLGSSLLMPVLTAVVLGGANIYGGSGSIIGTAIAALLIGYLQQGLQMVGVSNEISSALSGALLIIVLIGKSISLHYGAIV
QWIHRKTKSESTH
>Mature_333_residues
MFNMKKYSWEIALFCLVIIEILGFGMFNPRMLDLNVLLYSTSDFIYIGMLALPLTMIIVSGGMDISFGSTVGLCAIFLGV
LFKSDVPLSLAIPLTFLVGILCGVVNASLILYTKVNPLVITLGTMYLFGGGALLLSGFAGATGYEGIGGFPESLLEFANQ
TLFGIPTPIIYFLLMTLVFWLLMHKTTIGRSIFLIGQSERTSRYSAVPITGTLYIIYSAIGVVAAFVGILLVSYFGSARS
DLGSSLLMPVLTAVVLGGANIYGGSGSIIGTAIAALLIGYLQQGLQMVGVSNEISSALSGALLIIVLIGKSISLHYGAIV
QWIHRKTKSESTH

Specific function: Part of the ABC transporter complex lsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1172

COG function: function code G; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787794, Length=325, Percent_Identity=67.3846153846154, Blast_Score=420, Evalue=1e-119,
Organism=Escherichia coli, GI1790191, Length=291, Percent_Identity=28.5223367697594, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788896, Length=315, Percent_Identity=26.3492063492064, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790524, Length=308, Percent_Identity=25.6493506493506, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI145693152, Length=246, Percent_Identity=31.7073170731707, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787793, Length=286, Percent_Identity=30.4195804195804, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1788471, Length=211, Percent_Identity=31.7535545023697, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI87082395, Length=304, Percent_Identity=24.0131578947368, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI145693214, Length=284, Percent_Identity=25.3521126760563, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 35445; Mature: 35445

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNMKKYSWEIALFCLVIIEILGFGMFNPRMLDLNVLLYSTSDFIYIGMLALPLTMIIVS
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHC
GGMDISFGSTVGLCAIFLGVLFKSDVPLSLAIPLTFLVGILCGVVNASLILYTKVNPLVI
CCCCCCCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCEEEEEECCCEEE
TLGTMYLFGGGALLLSGFAGATGYEGIGGFPESLLEFANQTLFGIPTPIIYFLLMTLVFW
HHHHHHHHCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
LLMHKTTIGRSIFLIGQSERTSRYSAVPITGTLYIIYSAIGVVAAFVGILLVSYFGSARS
HHHHHHHCCCEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
DLGSSLLMPVLTAVVLGGANIYGGSGSIIGTAIAALLIGYLQQGLQMVGVSNEISSALSG
HHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ALLIIVLIGKSISLHYGAIVQWIHRKTKSESTH
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MFNMKKYSWEIALFCLVIIEILGFGMFNPRMLDLNVLLYSTSDFIYIGMLALPLTMIIVS
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHC
GGMDISFGSTVGLCAIFLGVLFKSDVPLSLAIPLTFLVGILCGVVNASLILYTKVNPLVI
CCCCCCCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCEEEEEECCCEEE
TLGTMYLFGGGALLLSGFAGATGYEGIGGFPESLLEFANQTLFGIPTPIIYFLLMTLVFW
HHHHHHHHCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
LLMHKTTIGRSIFLIGQSERTSRYSAVPITGTLYIIYSAIGVVAAFVGILLVSYFGSARS
HHHHHHHCCCEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
DLGSSLLMPVLTAVVLGGANIYGGSGSIIGTAIAALLIGYLQQGLQMVGVSNEISSALSG
HHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ALLIIVLIGKSISLHYGAIVQWIHRKTKSESTH
HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA