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The map label for this gene is gntR_2 [H]

Identifier: 15603096

GI number: 15603096

Start: 1422792

End: 1424249

Strand: Reverse

Name: gntR_2 [H]

Synonym: PM1231

Alternate gene names: 15603096

Gene position: 1424249-1422792 (Counterclockwise)

Preceding gene: 15603101

Following gene: 15603094

Centisome position: 63.09

GC content: 39.3

Gene sequence:

>1458_bases
ATGATTAAAAGTGTCAAAAAAGAGAAATTTAATGAGGTCAGAGTGATGCGTAAATTGAATTATCAGCTTGATAAGGGGAA
AAAAGAGCCCTTGTATTTACAACTTTATCAACAGCTCCGTGATTTAATTTATACACAGCAGCTTGCATTTGGAGAGCAAT
TACCTTCAAAAAGAGCCTTATGTGATTATTTGCAGATCAGTCAAAATACTGTGGAAGCTGCCTATGCGCAGCTACTCGCA
GAAGGTTATATTGAATCCATTGCGCGACGTGGTTTTTTTGTGTGCTTTCAACCTTCTTTGTTTTTTTCAGCACCAAAGCA
AACACAACCCCATACTGTAGCACCTCGCCATAGTACGATAGCCTTTGACTTTAATCCCCACTATATTGATAGTAAACATT
TTCCGTTAAAAAACTGGCGTAAGGCGGGTAAAGCGTTATTCCAAGCACGCCATTCAAGCTTATTAGGTCTTGGTGATAAA
CAAGGGGAGAGTCACCTTAGACAGCAGATTTGCGATTACCTTTTTTCATCGCGCGGTGTGAAATGTCATATTGATCAAAT
TATCATTTGTGGTGGTTTGGAAAATGCGATTCAGCAACTGATGTTGTTGTTTACGCACCTTTATCAAACGCCTGTTGTGC
ACTATGGTATGGAATTTTATGGTTATCAGACTTTAGAAAAGCTATTAACATTAGCCCACCAGAAAGTGATCAAGTTGCCT
CTGAATGCAGATGATCAACAGCTTGACCTTGATTTTTTAGCGCAAAGTTCAGTGAATATTGCGTGTGTAACGCCGTCGCA
TTTGTATCCCTTTGGTCATGTGCTTTCTATTACACAACGTCAACAATTACTAGCTTGGGCAAAAGCACAGCCACAGCGTT
ACATTATTGAAGATGATTATGACAGTGAATTTCGTTACCAAGGTAAACCAATCCCTGCGTTACAGAGTTTAGATAAGAAT
GACAGTGTGATTTATCTAGGTTCTTTTTCGAAGTTATTGATGCCTTCTTTGCGGGTTTCGTTTATGGTACTGCCCACGTC
ATTACTGGCAGCATATCAACAACATTGTGGGTTTATTAATTGTGCGGTTTCTCGCTTTGAACAGCAGCGTTTGGCTTATT
TTATGCAGCAAGGTGAATTTGAAAAACACATTAATCGTATGCGTAAAATATATCGACGAAAAATGGCACTGCTGTGTAGT
TTGCTTGCACCTTATGCAACTCAAATAAGATACTATGGTGAACATTCGGGATTTTATTTACTGATTGAACTTATTGCGGA
GTCAAGAAGTTTGGACACCTTAACACAATTGGCTTATGACAAGGGGGTTAAAGTGTATCCCGTAGATTGTGCGGCGCGTA
GGTTATTTTCTTTAGGCTTTGGTGATTTAAGTGAAACACAATTAGTGGAAGGCGTCAGCTGTTTATTGAATGCGTGGTTT
GCACAAGACGCTATTTGA

Upstream 100 bases:

>100_bases
TTTTGACGGTATCAGAACCTAAAATCGTATTCATATTTTGTCTCCTTTTATCATTGTATTATTGTGTATAAACTGCTGCT
ATTTTTGCGCTTATTTAGGT

Downstream 100 bases:

>100_bases
AAGAAATAGCGTCTTAAAAGTGCGGTCTGTTTTAGAAAAGTTCTTCCCGTTCTTGGATTGGGGAATTTTCGTTTATCTCA
TCAGATGGGATGTAGTAGCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MIKSVKKEKFNEVRVMRKLNYQLDKGKKEPLYLQLYQQLRDLIYTQQLAFGEQLPSKRALCDYLQISQNTVEAAYAQLLA
EGYIESIARRGFFVCFQPSLFFSAPKQTQPHTVAPRHSTIAFDFNPHYIDSKHFPLKNWRKAGKALFQARHSSLLGLGDK
QGESHLRQQICDYLFSSRGVKCHIDQIIICGGLENAIQQLMLLFTHLYQTPVVHYGMEFYGYQTLEKLLTLAHQKVIKLP
LNADDQQLDLDFLAQSSVNIACVTPSHLYPFGHVLSITQRQQLLAWAKAQPQRYIIEDDYDSEFRYQGKPIPALQSLDKN
DSVIYLGSFSKLLMPSLRVSFMVLPTSLLAAYQQHCGFINCAVSRFEQQRLAYFMQQGEFEKHINRMRKIYRRKMALLCS
LLAPYATQIRYYGEHSGFYLLIELIAESRSLDTLTQLAYDKGVKVYPVDCAARRLFSLGFGDLSETQLVEGVSCLLNAWF
AQDAI

Sequences:

>Translated_485_residues
MIKSVKKEKFNEVRVMRKLNYQLDKGKKEPLYLQLYQQLRDLIYTQQLAFGEQLPSKRALCDYLQISQNTVEAAYAQLLA
EGYIESIARRGFFVCFQPSLFFSAPKQTQPHTVAPRHSTIAFDFNPHYIDSKHFPLKNWRKAGKALFQARHSSLLGLGDK
QGESHLRQQICDYLFSSRGVKCHIDQIIICGGLENAIQQLMLLFTHLYQTPVVHYGMEFYGYQTLEKLLTLAHQKVIKLP
LNADDQQLDLDFLAQSSVNIACVTPSHLYPFGHVLSITQRQQLLAWAKAQPQRYIIEDDYDSEFRYQGKPIPALQSLDKN
DSVIYLGSFSKLLMPSLRVSFMVLPTSLLAAYQQHCGFINCAVSRFEQQRLAYFMQQGEFEKHINRMRKIYRRKMALLCS
LLAPYATQIRYYGEHSGFYLLIELIAESRSLDTLTQLAYDKGVKVYPVDCAARRLFSLGFGDLSETQLVEGVSCLLNAWF
AQDAI
>Mature_485_residues
MIKSVKKEKFNEVRVMRKLNYQLDKGKKEPLYLQLYQQLRDLIYTQQLAFGEQLPSKRALCDYLQISQNTVEAAYAQLLA
EGYIESIARRGFFVCFQPSLFFSAPKQTQPHTVAPRHSTIAFDFNPHYIDSKHFPLKNWRKAGKALFQARHSSLLGLGDK
QGESHLRQQICDYLFSSRGVKCHIDQIIICGGLENAIQQLMLLFTHLYQTPVVHYGMEFYGYQTLEKLLTLAHQKVIKLP
LNADDQQLDLDFLAQSSVNIACVTPSHLYPFGHVLSITQRQQLLAWAKAQPQRYIIEDDYDSEFRYQGKPIPALQSLDKN
DSVIYLGSFSKLLMPSLRVSFMVLPTSLLAAYQQHCGFINCAVSRFEQQRLAYFMQQGEFEKHINRMRKIYRRKMALLCS
LLAPYATQIRYYGEHSGFYLLIELIAESRSLDTLTQLAYDKGVKVYPVDCAARRLFSLGFGDLSETQLVEGVSCLLNAWF
AQDAI

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790797, Length=404, Percent_Identity=27.2277227722772, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787710, Length=414, Percent_Identity=25.1207729468599, Blast_Score=93, Evalue=5e-20,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 55801; Mature: 55801

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKSVKKEKFNEVRVMRKLNYQLDKGKKEPLYLQLYQQLRDLIYTQQLAFGEQLPSKRAL
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
CDYLQISQNTVEAAYAQLLAEGYIESIARRGFFVCFQPSLFFSAPKQTQPHTVAPRHSTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHCCCCCCCCCCCCCCCCCEE
AFDFNPHYIDSKHFPLKNWRKAGKALFQARHSSLLGLGDKQGESHLRQQICDYLFSSRGV
EEECCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC
KCHIDQIIICGGLENAIQQLMLLFTHLYQTPVVHYGMEFYGYQTLEKLLTLAHQKVIKLP
EEEECCEEEECCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
LNADDQQLDLDFLAQSSVNIACVTPSHLYPFGHVLSITQRQQLLAWAKAQPQRYIIEDDY
CCCCCCCCCHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
DSEFRYQGKPIPALQSLDKNDSVIYLGSFSKLLMPSLRVSFMVLPTSLLAAYQQHCGFIN
CCCCEECCCCCHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
CAVSRFEQQRLAYFMQQGEFEKHINRMRKIYRRKMALLCSLLAPYATQIRYYGEHSGFYL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHH
LIELIAESRSLDTLTQLAYDKGVKVYPVDCAARRLFSLGFGDLSETQLVEGVSCLLNAWF
HHHHHHCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
AQDAI
HHCCC
>Mature Secondary Structure
MIKSVKKEKFNEVRVMRKLNYQLDKGKKEPLYLQLYQQLRDLIYTQQLAFGEQLPSKRAL
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
CDYLQISQNTVEAAYAQLLAEGYIESIARRGFFVCFQPSLFFSAPKQTQPHTVAPRHSTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHCCCCCCCCCCCCCCCCCEE
AFDFNPHYIDSKHFPLKNWRKAGKALFQARHSSLLGLGDKQGESHLRQQICDYLFSSRGV
EEECCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC
KCHIDQIIICGGLENAIQQLMLLFTHLYQTPVVHYGMEFYGYQTLEKLLTLAHQKVIKLP
EEEECCEEEECCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
LNADDQQLDLDFLAQSSVNIACVTPSHLYPFGHVLSITQRQQLLAWAKAQPQRYIIEDDY
CCCCCCCCCHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
DSEFRYQGKPIPALQSLDKNDSVIYLGSFSKLLMPSLRVSFMVLPTSLLAAYQQHCGFIN
CCCCEECCCCCHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
CAVSRFEQQRLAYFMQQGEFEKHINRMRKIYRRKMALLCSLLAPYATQIRYYGEHSGFYL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHH
LIELIAESRSLDTLTQLAYDKGVKVYPVDCAARRLFSLGFGDLSETQLVEGVSCLLNAWF
HHHHHHCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
AQDAI
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]