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The map label for this gene is secA

Identifier: 15603084

GI number: 15603084

Start: 1410251

End: 1412938

Strand: Reverse

Name: secA

Synonym: PM1219

Alternate gene names: 15603084

Gene position: 1412938-1410251 (Counterclockwise)

Preceding gene: 15603085

Following gene: 15603083

Centisome position: 62.59

GC content: 41.96

Gene sequence:

>2688_bases
ATGTTTAGAAGTATTCTCACCAAAATTTTTGGCAGCCGTAATGATCGGATTTTACGTCGATTGAATAAAATTGTTATTAA
GATTAATCAGTTAGAGCCTGAGTTTGAAGCCTTAAGCGATGATGATTTAAAAGCGAAGACTGATGCCTTTAAAGCACGTT
TAGCACAGGGTGAAACATTAGAGCAACTTTTACCTGAAGCATTTGCCACAGTGCGTGAAGCAAGCAAACGTGTATTAGGC
ATGCGCCATTTTGATGTGCAATTGTTGGGGGGAATGGTACTGACTAACCGTTGTATTGCGGAGATGCGTACAGGGGAAGG
GAAAACATTAACCGCGACCTTACCTTGCTATTTAAATGCGCTAACGGGGAAAGGTGTGCATGTTGTGACGGTGAATGATT
ATTTGGCTCGTCGGGATGCGGAAACGAATCGTCCACTTTTTGAATTTTTAGGTATGACGGTGGGCGTGAATGTTCCTGGT
TTATCACCAGAGCAAAAACGTGAAGCTTATGCGGCAGATGTAACATATGCAACCAATAGTGAATTAGGCTTTGATTATTT
ACGTGATAATTTAGCTCATACTGCACAAGAACGTTTTCAACGTTATTTACATTATGCGTTAGTGGATGAGGTGGATTCTA
TTTTAATTGATGAAGCCAGAACACCGTTGATTATTTCAGGGCAAGCCGAAGATAGCTCAGAATTGTATATGACGGTTGAT
AAATTGATTCCGGATTTAATCAAACAAGATAAAGAAGATTCAGAAGAATATCAAGGTGAAGGAGACTTCACTTTAGACTT
AAAAACCAAGCAAGCGCATTTAACTGAGCGAGGTCAAGAGAAAGTCGAACAATGGCTGACTGAACAAGGGTTAATGAGTG
CGGAGGAATCTTTGTATTCGCCGTCAAAAATTTCCTTGTTGCATCATGTGTACGCGGCATTACGTGCCCATACTTTATTT
GAGCGTGATGTAGATTACATCGTGAAAGACGGTGAAATCGTGATTGTTGACGAGCACACTGGTCGTACTATGGCGGGTCG
TCGTTGGTCAGACGGCTTACACCAAGCGATTGAAGCCAAAGAAGGTGTGCGCATTCAAAGCGAGAACCAGACCGTTGCCT
CAATCACCTACCAAAACTATTTCCGCTTGTATGAAAAACTAGCAGGGATGACCGGTACTGCGGACACTGAAGCCTTTGAG
TTCCAACAAATTTATGGGCTAGAAACTATTGTCGTGCCAACTAATCGTCCGATGATTCGTGATGATCGTACTGACGTCAT
GTTCGAGAATGAAGAGTATAAATTTAATGCGATTATTGAGGACATTAAAGATTGTGTGGCACGTAATCAACCAGTGTTAG
TCGGGACAATCTCCATTGAAAAATCAGAATTACTCTCTCATGCATTGAAAAAAGCCGGCATTAAACACAATGTGCTAAAT
GCGAAATTCCACGCACAGGAAGCCGAAATCGTGGCAAACGCCGGGTATCCAGGTACGGTGACGATTGCCACCAATATGGC
AGGTCGTGGTACAGATATTGTACTAGGTGGTAACTGGAAAGCCGAAATTGCGAAGTTGGATAATCCGACAGAAGCACAAA
TTGAGGCAATTCATACTGCTTGGAAAGCGCGTCATGAGATCGTGAAAGCCGCGGGGGGATTGCATATTATTGGAACGGAA
CGTCATGAGTCACGTCGTATTGATAATCAGTTGCGCGGTCGTTCTGGTCGTCAAGGTGACCCAGGATCTTCACGTTTCTA
TTTATCGTTAGATGACGCGCTGATGCGTATTTATCTAAATGAAGGTAAGTTAAACTTAATGCGCAAAGCCTTTAGCACCG
CAGGCGAAGCGATGGAGTCAAAAATGTTGACCAAAGTGATTGCCTCCGCACAAGCTAAAGTGGAAGCGCATAACTTTGAT
GGTCGTAAAAACTTACTTGAGTTTGATGATGTTGCTAATGACCAACGTCATGCTATTTATGCACAACGTAATACGTTGTT
AGATAATGAGGATATTTCTGACACGATTGATGTGATTCGCGCGGATGTCTTTAATCAAGTGATTGATCAATATATTCCAC
CACAATCTTTAGAAGAAATGTGGGATGTACCTGCACTAGAGCAACGTTTGAAACATGACTTTGCCTTAGATTTACCGCTT
GAAAAATGGTTAGAAGAAGATAATCATTTTGATGAAGATGCATTACGTCAGCGTGTATTAGATGCAGCGATTGAGGAATA
CAAGCAAAAAGAAAGCATTGTGGGTGAACAAACCATGCGTAGCTTTGAAAAAGGCGTGATGTTACAAACTCTTGATGAAT
TGTGGAAAGAACATTTATCAGCAATGGATCATTTACGTCGTGGTATCCATTTGCGTGGTTATGCACAAAAAGATCCAAAA
CAGGAATACAAAAAAGAATGTTTCCAAATGTTTACGGATATGCTTGATGCCTTGAAGTTGAGTGTTGTGACGACGTTAAG
TCGTGTACAAGTACGTACACAAGAAGAGGTTGAACAAGCGGAGCGTCAGCGTCAAGAGATGGCAAAACGCGAAACGGCCA
GTATGCAATATAATGCAGACGAAGACAGTGGCGAAGAGAACACACGTCGTGTGGGACGAAATGAGCCATGTCCTTGTGGG
TCTGGCAAGAAATATAAACATTGCCATGGCAGTAAAGCTAAATATTAA

Upstream 100 bases:

>100_bases
GTCCGATTAGCGTCTAACTTAACTCGTTGACTTATTTACTCTGTTTTGTATTGAACGGCAAAGCAGATCCGTTATTCATT
TTATAAGAAAGAAAAAAATT

Downstream 100 bases:

>100_bases
TCTTGTGTATAAGATGATTTAAGTAGATATAAAAGTGCGGTATGTTTTTAAAAAATTTTTAAAACTGACCGCACTTTTTT
TAAGGATACATCATGACAAA

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 895; Mature: 895

Protein sequence:

>895_residues
MFRSILTKIFGSRNDRILRRLNKIVIKINQLEPEFEALSDDDLKAKTDAFKARLAQGETLEQLLPEAFATVREASKRVLG
MRHFDVQLLGGMVLTNRCIAEMRTGEGKTLTATLPCYLNALTGKGVHVVTVNDYLARRDAETNRPLFEFLGMTVGVNVPG
LSPEQKREAYAADVTYATNSELGFDYLRDNLAHTAQERFQRYLHYALVDEVDSILIDEARTPLIISGQAEDSSELYMTVD
KLIPDLIKQDKEDSEEYQGEGDFTLDLKTKQAHLTERGQEKVEQWLTEQGLMSAEESLYSPSKISLLHHVYAALRAHTLF
ERDVDYIVKDGEIVIVDEHTGRTMAGRRWSDGLHQAIEAKEGVRIQSENQTVASITYQNYFRLYEKLAGMTGTADTEAFE
FQQIYGLETIVVPTNRPMIRDDRTDVMFENEEYKFNAIIEDIKDCVARNQPVLVGTISIEKSELLSHALKKAGIKHNVLN
AKFHAQEAEIVANAGYPGTVTIATNMAGRGTDIVLGGNWKAEIAKLDNPTEAQIEAIHTAWKARHEIVKAAGGLHIIGTE
RHESRRIDNQLRGRSGRQGDPGSSRFYLSLDDALMRIYLNEGKLNLMRKAFSTAGEAMESKMLTKVIASAQAKVEAHNFD
GRKNLLEFDDVANDQRHAIYAQRNTLLDNEDISDTIDVIRADVFNQVIDQYIPPQSLEEMWDVPALEQRLKHDFALDLPL
EKWLEEDNHFDEDALRQRVLDAAIEEYKQKESIVGEQTMRSFEKGVMLQTLDELWKEHLSAMDHLRRGIHLRGYAQKDPK
QEYKKECFQMFTDMLDALKLSVVTTLSRVQVRTQEEVEQAERQRQEMAKRETASMQYNADEDSGEENTRRVGRNEPCPCG
SGKKYKHCHGSKAKY

Sequences:

>Translated_895_residues
MFRSILTKIFGSRNDRILRRLNKIVIKINQLEPEFEALSDDDLKAKTDAFKARLAQGETLEQLLPEAFATVREASKRVLG
MRHFDVQLLGGMVLTNRCIAEMRTGEGKTLTATLPCYLNALTGKGVHVVTVNDYLARRDAETNRPLFEFLGMTVGVNVPG
LSPEQKREAYAADVTYATNSELGFDYLRDNLAHTAQERFQRYLHYALVDEVDSILIDEARTPLIISGQAEDSSELYMTVD
KLIPDLIKQDKEDSEEYQGEGDFTLDLKTKQAHLTERGQEKVEQWLTEQGLMSAEESLYSPSKISLLHHVYAALRAHTLF
ERDVDYIVKDGEIVIVDEHTGRTMAGRRWSDGLHQAIEAKEGVRIQSENQTVASITYQNYFRLYEKLAGMTGTADTEAFE
FQQIYGLETIVVPTNRPMIRDDRTDVMFENEEYKFNAIIEDIKDCVARNQPVLVGTISIEKSELLSHALKKAGIKHNVLN
AKFHAQEAEIVANAGYPGTVTIATNMAGRGTDIVLGGNWKAEIAKLDNPTEAQIEAIHTAWKARHEIVKAAGGLHIIGTE
RHESRRIDNQLRGRSGRQGDPGSSRFYLSLDDALMRIYLNEGKLNLMRKAFSTAGEAMESKMLTKVIASAQAKVEAHNFD
GRKNLLEFDDVANDQRHAIYAQRNTLLDNEDISDTIDVIRADVFNQVIDQYIPPQSLEEMWDVPALEQRLKHDFALDLPL
EKWLEEDNHFDEDALRQRVLDAAIEEYKQKESIVGEQTMRSFEKGVMLQTLDELWKEHLSAMDHLRRGIHLRGYAQKDPK
QEYKKECFQMFTDMLDALKLSVVTTLSRVQVRTQEEVEQAERQRQEMAKRETASMQYNADEDSGEENTRRVGRNEPCPCG
SGKKYKHCHGSKAKY
>Mature_895_residues
MFRSILTKIFGSRNDRILRRLNKIVIKINQLEPEFEALSDDDLKAKTDAFKARLAQGETLEQLLPEAFATVREASKRVLG
MRHFDVQLLGGMVLTNRCIAEMRTGEGKTLTATLPCYLNALTGKGVHVVTVNDYLARRDAETNRPLFEFLGMTVGVNVPG
LSPEQKREAYAADVTYATNSELGFDYLRDNLAHTAQERFQRYLHYALVDEVDSILIDEARTPLIISGQAEDSSELYMTVD
KLIPDLIKQDKEDSEEYQGEGDFTLDLKTKQAHLTERGQEKVEQWLTEQGLMSAEESLYSPSKISLLHHVYAALRAHTLF
ERDVDYIVKDGEIVIVDEHTGRTMAGRRWSDGLHQAIEAKEGVRIQSENQTVASITYQNYFRLYEKLAGMTGTADTEAFE
FQQIYGLETIVVPTNRPMIRDDRTDVMFENEEYKFNAIIEDIKDCVARNQPVLVGTISIEKSELLSHALKKAGIKHNVLN
AKFHAQEAEIVANAGYPGTVTIATNMAGRGTDIVLGGNWKAEIAKLDNPTEAQIEAIHTAWKARHEIVKAAGGLHIIGTE
RHESRRIDNQLRGRSGRQGDPGSSRFYLSLDDALMRIYLNEGKLNLMRKAFSTAGEAMESKMLTKVIASAQAKVEAHNFD
GRKNLLEFDDVANDQRHAIYAQRNTLLDNEDISDTIDVIRADVFNQVIDQYIPPQSLEEMWDVPALEQRLKHDFALDLPL
EKWLEEDNHFDEDALRQRVLDAAIEEYKQKESIVGEQTMRSFEKGVMLQTLDELWKEHLSAMDHLRRGIHLRGYAQKDPK
QEYKKECFQMFTDMLDALKLSVVTTLSRVQVRTQEEVEQAERQRQEMAKRETASMQYNADEDSGEENTRRVGRNEPCPCG
SGKKYKHCHGSKAKY

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the pr

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family

Homologues:

Organism=Escherichia coli, GI1786287, Length=899, Percent_Identity=69.7441601779755, Blast_Score=1306, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECA_PASMU (Q9CLK7)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246156.1
- HSSP:   P43803
- ProteinModelPortal:   Q9CLK7
- SMR:   Q9CLK7
- GeneID:   1244566
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1219
- NMPDR:   fig|272843.1.peg.1219
- HOGENOM:   HBG284200
- OMA:   GGMVLHD
- ProtClustDB:   PRK12904
- BioCyc:   PMUL272843:PM1219-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01382
- InterPro:   IPR004027
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116
- Gene3D:   G3DSA:1.10.3060.10
- PRINTS:   PR00906
- SMART:   SM00957
- SMART:   SM00958
- TIGRFAMs:   TIGR00963

Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW; SSF81767 SecA_PP_bd; SSF81886 SecA_SW

EC number: NA

Molecular weight: Translated: 101733; Mature: 101733

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS01312 SECA; PS51196 SECA_MOTOR_DEAD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRSILTKIFGSRNDRILRRLNKIVIKINQLEPEFEALSDDDLKAKTDAFKARLAQGETL
CHHHHHHHHHCCCCHHHHHHHHHHEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHCCCHH
EQLLPEAFATVREASKRVLGMRHFDVQLLGGMVLTNRCIAEMRTGEGKTLTATLPCYLNA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHH
LTGKGVHVVTVNDYLARRDAETNRPLFEFLGMTVGVNVPGLSPEQKREAYAADVTYATNS
HCCCCEEEEEECHHHHHCCCCCCCHHHHHHCCCEECCCCCCCCHHHHHHHHHCEEEECCC
ELGFDYLRDNLAHTAQERFQRYLHYALVDEVDSILIDEARTPLIISGQAEDSSELYMTVD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHH
KLIPDLIKQDKEDSEEYQGEGDFTLDLKTKQAHLTERGQEKVEQWLTEQGLMSAEESLYS
HHHHHHHHCCCCCHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PSKISLLHHVYAALRAHTLFERDVDYIVKDGEIVIVDEHTGRTMAGRRWSDGLHQAIEAK
CHHHHHHHHHHHHHHHHHHHHHCHHHEEECCEEEEEECCCCCCCCCCCHHHHHHHHHHHH
EGVRIQSENQTVASITYQNYFRLYEKLAGMTGTADTEAFEFQQIYGLETIVVPTNRPMIR
CCCEEECCCCEEEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCEEEEECCCCCCCC
DDRTDVMFENEEYKFNAIIEDIKDCVARNQPVLVGTISIEKSELLSHALKKAGIKHNVLN
CCCCCEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHCCCCCCCCC
AKFHAQEAEIVANAGYPGTVTIATNMAGRGTDIVLGGNWKAEIAKLDNPTEAQIEAIHTA
CHHCCCCHHEEECCCCCEEEEEEECCCCCCCEEEECCCCCCHHEECCCCCHHHHHHHHHH
WKARHEIVKAAGGLHIIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLDDALMRIYLN
HHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHC
EGKLNLMRKAFSTAGEAMESKMLTKVIASAQAKVEAHNFDGRKNLLEFDDVANDQRHAIY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHCCCCCHHEEE
AQRNTLLDNEDISDTIDVIRADVFNQVIDQYIPPQSLEEMWDVPALEQRLKHDFALDLPL
EHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHCCCCEECCCH
EKWLEEDNHFDEDALRQRVLDAAIEEYKQKESIVGEQTMRSFEKGVMLQTLDELWKEHLS
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
AMDHLRRGIHLRGYAQKDPKQEYKKECFQMFTDMLDALKLSVVTTLSRVQVRTQEEVEQA
HHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERQRQEMAKRETASMQYNADEDSGEENTRRVGRNEPCPCGSGKKYKHCHGSKAKY
HHHHHHHHHHHHHCCEECCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFRSILTKIFGSRNDRILRRLNKIVIKINQLEPEFEALSDDDLKAKTDAFKARLAQGETL
CHHHHHHHHHCCCCHHHHHHHHHHEEEEECCCCHHHHCCCCCCHHHHHHHHHHHHCCCHH
EQLLPEAFATVREASKRVLGMRHFDVQLLGGMVLTNRCIAEMRTGEGKTLTATLPCYLNA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHH
LTGKGVHVVTVNDYLARRDAETNRPLFEFLGMTVGVNVPGLSPEQKREAYAADVTYATNS
HCCCCEEEEEECHHHHHCCCCCCCHHHHHHCCCEECCCCCCCCHHHHHHHHHCEEEECCC
ELGFDYLRDNLAHTAQERFQRYLHYALVDEVDSILIDEARTPLIISGQAEDSSELYMTVD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHH
KLIPDLIKQDKEDSEEYQGEGDFTLDLKTKQAHLTERGQEKVEQWLTEQGLMSAEESLYS
HHHHHHHHCCCCCHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PSKISLLHHVYAALRAHTLFERDVDYIVKDGEIVIVDEHTGRTMAGRRWSDGLHQAIEAK
CHHHHHHHHHHHHHHHHHHHHHCHHHEEECCEEEEEECCCCCCCCCCCHHHHHHHHHHHH
EGVRIQSENQTVASITYQNYFRLYEKLAGMTGTADTEAFEFQQIYGLETIVVPTNRPMIR
CCCEEECCCCEEEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCEEEEECCCCCCCC
DDRTDVMFENEEYKFNAIIEDIKDCVARNQPVLVGTISIEKSELLSHALKKAGIKHNVLN
CCCCCEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHCCCCCCCCC
AKFHAQEAEIVANAGYPGTVTIATNMAGRGTDIVLGGNWKAEIAKLDNPTEAQIEAIHTA
CHHCCCCHHEEECCCCCEEEEEEECCCCCCCEEEECCCCCCHHEECCCCCHHHHHHHHHH
WKARHEIVKAAGGLHIIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLDDALMRIYLN
HHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHC
EGKLNLMRKAFSTAGEAMESKMLTKVIASAQAKVEAHNFDGRKNLLEFDDVANDQRHAIY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHCCCCCHHEEE
AQRNTLLDNEDISDTIDVIRADVFNQVIDQYIPPQSLEEMWDVPALEQRLKHDFALDLPL
EHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHCCCCEECCCH
EKWLEEDNHFDEDALRQRVLDAAIEEYKQKESIVGEQTMRSFEKGVMLQTLDELWKEHLS
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
AMDHLRRGIHLRGYAQKDPKQEYKKECFQMFTDMLDALKLSVVTTLSRVQVRTQEEVEQA
HHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERQRQEMAKRETASMQYNADEDSGEENTRRVGRNEPCPCGSGKKYKHCHGSKAKY
HHHHHHHHHHHHHCCEECCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11248100