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The map label for this gene is argB

Identifier: 15602984

GI number: 15602984

Start: 1317707

End: 1318480

Strand: Direct

Name: argB

Synonym: PM1119

Alternate gene names: 15602984

Gene position: 1317707-1318480 (Clockwise)

Preceding gene: 15602983

Following gene: 15602985

Centisome position: 58.37

GC content: 41.86

Gene sequence:

>774_bases
ATGAAACCTTTAGTGATTAAATTAGGTGGTGTCTTACTTGATACACCTGCAGCAATGGAAAATTTATTTACGGCGTTAGC
AAATTACCAACAAAACTTTGATCGCCCGTTGGTCATTGTGCACGGTGGTGGCTGTATTGTTGATGAGTTGATGCAACGTT
TACATTTGCCAGTACAAAAGAAAAATGGTTTGCGTGTCACGCCAAGTGATCACATTGAGATTATTACGGGTGCGTTAGCC
GGCATTGCCAATAAAACTTTAGTTGCGCAAGCCGCCAAATTTCATTTAAATCCCGTCGGACTATGTTTGGCAGACGGGAA
TTTAACCTATGCAACGCAATTAGATCCAGAACTTGGACATGTGGCGACTGTGGTTCCTAAAAATCCCGCCTTATTAAACA
ATTTGCTTGGTGAGGCATTCTTGCCTATTATTAGCTCAATTGCGGTCGATAAACAGGGCTTATTAATGAATGTGAATGCA
GATCAAGCTGCCACAGCTATCGCCGCGCTCATCCAAGCCGATTTAGTCATGTTATCTGACGTCGATGGCGTATTGGATGC
CAACAAACAGCGCTTACCAGAATTAAATGGTGCGCAAATTGAACAATTAATTAAAGACAACGTCATTACCGATGGTATGG
TTGTCAAGGTGAATGCCGCATTAGACGCTGCTAAAATGTTAAATCAGGGCGTCGATATCGCCAATTGGAAATATCCAGAA
AAACTCACCGCACTTTTTGCTGGTGAAATCATTGGCACAAGAATTAAACCATAA

Upstream 100 bases:

>100_bases
CATCGGCGCAGAAGACAACTTATTAAAAGGGGCAGCAGCACAGGCAGTACAATGTGCTAACATTCGTTATGGTTTGACTG
AAACATTAGGATTACTTTAA

Downstream 100 bases:

>100_bases
AAATAAGAGGATGTTATGGCACTTTGGGGTGGACGTTTTACACAAGCCGCAGATAAGCGTTTTAAAGATTTTAATGACTC
ATTACGTTTCGATTATCGTC

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MKPLVIKLGGVLLDTPAAMENLFTALANYQQNFDRPLVIVHGGGCIVDELMQRLHLPVQKKNGLRVTPSDHIEIITGALA
GIANKTLVAQAAKFHLNPVGLCLADGNLTYATQLDPELGHVATVVPKNPALLNNLLGEAFLPIISSIAVDKQGLLMNVNA
DQAATAIAALIQADLVMLSDVDGVLDANKQRLPELNGAQIEQLIKDNVITDGMVVKVNAALDAAKMLNQGVDIANWKYPE
KLTALFAGEIIGTRIKP

Sequences:

>Translated_257_residues
MKPLVIKLGGVLLDTPAAMENLFTALANYQQNFDRPLVIVHGGGCIVDELMQRLHLPVQKKNGLRVTPSDHIEIITGALA
GIANKTLVAQAAKFHLNPVGLCLADGNLTYATQLDPELGHVATVVPKNPALLNNLLGEAFLPIISSIAVDKQGLLMNVNA
DQAATAIAALIQADLVMLSDVDGVLDANKQRLPELNGAQIEQLIKDNVITDGMVVKVNAALDAAKMLNQGVDIANWKYPE
KLTALFAGEIIGTRIKP
>Mature_257_residues
MKPLVIKLGGVLLDTPAAMENLFTALANYQQNFDRPLVIVHGGGCIVDELMQRLHLPVQKKNGLRVTPSDHIEIITGALA
GIANKTLVAQAAKFHLNPVGLCLADGNLTYATQLDPELGHVATVVPKNPALLNNLLGEAFLPIISSIAVDKQGLLMNVNA
DQAATAIAALIQADLVMLSDVDGVLDANKQRLPELNGAQIEQLIKDNVITDGMVVKVNAALDAAKMLNQGVDIANWKYPE
KLTALFAGEIIGTRIKP

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI145693208, Length=255, Percent_Identity=61.9607843137255, Blast_Score=305, Evalue=2e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGB_PASMU (P57908)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246056.1
- ProteinModelPortal:   P57908
- SMR:   P57908
- GeneID:   1244466
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1119
- NMPDR:   fig|272843.1.peg.1119
- HOGENOM:   HBG497643
- OMA:   MVLCGST
- ProtClustDB:   PRK00942
- BioCyc:   PMUL272843:PM1119-MONOMER
- BRENDA:   2.7.2.8
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 27367; Mature: 27367

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: BINDING 65-65 BINDING 157-157

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPLVIKLGGVLLDTPAAMENLFTALANYQQNFDRPLVIVHGGGCIVDELMQRLHLPVQK
CCCEEEEECCEEEECHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCCCC
KNGLRVTPSDHIEIITGALAGIANKTLVAQAAKFHLNPVGLCLADGNLTYATQLDPELGH
CCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEEECCCCCCC
VATVVPKNPALLNNLLGEAFLPIISSIAVDKQGLLMNVNADQAATAIAALIQADLVMLSD
EEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHC
VDGVLDANKQRLPELNGAQIEQLIKDNVITDGMVVKVNAALDAAKMLNQGVDIANWKYPE
CCHHHCCCHHHCCCCCHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHCCCCCCCCCCHH
KLTALFAGEIIGTRIKP
HHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKPLVIKLGGVLLDTPAAMENLFTALANYQQNFDRPLVIVHGGGCIVDELMQRLHLPVQK
CCCEEEEECCEEEECHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCCCC
KNGLRVTPSDHIEIITGALAGIANKTLVAQAAKFHLNPVGLCLADGNLTYATQLDPELGH
CCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEEECCCCCCC
VATVVPKNPALLNNLLGEAFLPIISSIAVDKQGLLMNVNADQAATAIAALIQADLVMLSD
EEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHC
VDGVLDANKQRLPELNGAQIEQLIKDNVITDGMVVKVNAALDAAKMLNQGVDIANWKYPE
CCHHHCCCHHHCCCCCHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHCCCCCCCCCCHH
KLTALFAGEIIGTRIKP
HHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100