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The map label for this gene is argC

Identifier: 15602983

GI number: 15602983

Start: 1316699

End: 1317706

Strand: Direct

Name: argC

Synonym: PM1118

Alternate gene names: 15602983

Gene position: 1316699-1317706 (Clockwise)

Preceding gene: 15602981

Following gene: 15602984

Centisome position: 58.33

GC content: 42.26

Gene sequence:

>1008_bases
ATGCAAAAAGCGATTATCATTGGTGCAAGTGGTTATACGGGGGCTGAACTTGCTCGTCTTTTAATCAAACACCCCGAGTT
TGAGCTCACCGGACTGTACGTCTCTCGCCAAAGCCAAGATGCCAATAAATGCATAAGTGACATTTATCCACAACTCAAGC
ACCTTGTGGATTTACCTTTACAGCCACTGCCTGAACAATTAACTCAACTTGCACAACAAGCGGATCTGGTGTTTCTCGCC
ACCGCTCATGAAGTCAGCCATGACCTTGCCCCCATTTTCCTACAAAATCAATGTAAAGTCTTTGACTTATCTGGCGCATT
TCGTGTGAATAATGCGGCATTTTATCGCACGTTTTATGGTTTTGAGCATCAACATCCTGAATTGCTCACACAAGCGGTGT
ATGGTTTAGCGGAATGGAATGCACATCAAATTAAACAAACGGATTTAGTAGCCGTCGCGGGCTGTTATCCAACCGTCTCT
CAATTAAGCCTTAAACCCTTAATTGCACACAATTTATTAGATTTAACCCAATTACCTGTGATTAATGCCGTCAGCGGAGT
CAGTGGTGCCGGTCGCAAAGCAACTTTAACAAGCAGTTTCTGTGAAGTCAGTTTAAATGCTTACGGTGTGTTTAATCACC
GTCATCAACCTGAAATAGCGACCCATTTGGGGACAGAGGTCATTTTCACACCACACTTAGGTAACTTTAAACGCGGTATT
TTAGCGACAATCACAGCAAAACTAAAAACCGGCGTGAGTGATGAACAGATTCGTGTAGCTTATCAACACGCCTATGCTGA
CAAACCATTAGTCCGTGTTTATGAACAAGGTTTACCAAGTATCAAAGCCGTCGAATTTACTCCTTATTGTGATATTGGCT
TTGTGACTAAAAATGGTCATATCATTATCATCGGCGCAGAAGACAACTTATTAAAAGGGGCAGCAGCACAGGCAGTACAA
TGTGCTAACATTCGTTATGGTTTGACTGAAACATTAGGATTACTTTAA

Upstream 100 bases:

>100_bases
CCCTTGATAAACAGAAAGACATTGCCTTTTAAATATTTATGCATAATAATAGCATAATTAGTCATTTAAAAATTTATCTT
ATTATAAGGCACAACACAAT

Downstream 100 bases:

>100_bases
ATGAAACCTTTAGTGATTAAATTAGGTGGTGTCTTACTTGATACACCTGCAGCAATGGAAAATTTATTTACGGCGTTAGC
AAATTACCAACAAAACTTTG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MQKAIIIGASGYTGAELARLLIKHPEFELTGLYVSRQSQDANKCISDIYPQLKHLVDLPLQPLPEQLTQLAQQADLVFLA
TAHEVSHDLAPIFLQNQCKVFDLSGAFRVNNAAFYRTFYGFEHQHPELLTQAVYGLAEWNAHQIKQTDLVAVAGCYPTVS
QLSLKPLIAHNLLDLTQLPVINAVSGVSGAGRKATLTSSFCEVSLNAYGVFNHRHQPEIATHLGTEVIFTPHLGNFKRGI
LATITAKLKTGVSDEQIRVAYQHAYADKPLVRVYEQGLPSIKAVEFTPYCDIGFVTKNGHIIIIGAEDNLLKGAAAQAVQ
CANIRYGLTETLGLL

Sequences:

>Translated_335_residues
MQKAIIIGASGYTGAELARLLIKHPEFELTGLYVSRQSQDANKCISDIYPQLKHLVDLPLQPLPEQLTQLAQQADLVFLA
TAHEVSHDLAPIFLQNQCKVFDLSGAFRVNNAAFYRTFYGFEHQHPELLTQAVYGLAEWNAHQIKQTDLVAVAGCYPTVS
QLSLKPLIAHNLLDLTQLPVINAVSGVSGAGRKATLTSSFCEVSLNAYGVFNHRHQPEIATHLGTEVIFTPHLGNFKRGI
LATITAKLKTGVSDEQIRVAYQHAYADKPLVRVYEQGLPSIKAVEFTPYCDIGFVTKNGHIIIIGAEDNLLKGAAAQAVQ
CANIRYGLTETLGLL
>Mature_335_residues
MQKAIIIGASGYTGAELARLLIKHPEFELTGLYVSRQSQDANKCISDIYPQLKHLVDLPLQPLPEQLTQLAQQADLVFLA
TAHEVSHDLAPIFLQNQCKVFDLSGAFRVNNAAFYRTFYGFEHQHPELLTQAVYGLAEWNAHQIKQTDLVAVAGCYPTVS
QLSLKPLIAHNLLDLTQLPVINAVSGVSGAGRKATLTSSFCEVSLNAYGVFNHRHQPEIATHLGTEVIFTPHLGNFKRGI
LATITAKLKTGVSDEQIRVAYQHAYADKPLVRVYEQGLPSIKAVEFTPYCDIGFVTKNGHIIIIGAEDNLLKGAAAQAVQ
CANIRYGLTETLGLL

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=335, Percent_Identity=63.5820895522388, Blast_Score=441, Evalue=1e-125,
Organism=Saccharomyces cerevisiae, GI6320913, Length=358, Percent_Identity=29.0502793296089, Blast_Score=115, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_PASMU (P57907)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246055.1
- ProteinModelPortal:   P57907
- SMR:   P57907
- GeneID:   1244465
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1118
- NMPDR:   fig|272843.1.peg.1118
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- ProtClustDB:   PRK00436
- BioCyc:   PMUL272843:PM1118-MONOMER
- BRENDA:   1.2.1.38
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 36698; Mature: 36698

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS01224 ARGC; PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 155-155

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKAIIIGASGYTGAELARLLIKHPEFELTGLYVSRQSQDANKCISDIYPQLKHLVDLPL
CCCEEEEECCCCCHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCC
QPLPEQLTQLAQQADLVFLATAHEVSHDLAPIFLQNQCKVFDLSGAFRVNNAAFYRTFYG
CCCHHHHHHHHHHCCEEEEEEHHHHCCCCCCEEECCCCEEEECCCCEEECCEEEEEEECC
FEHQHPELLTQAVYGLAEWNAHQIKQTDLVAVAGCYPTVSQLSLKPLIAHNLLDLTQLPV
CCCCCHHHHHHHHHHHHCCCHHHCCCCCEEEEECCCCCHHHHCCCHHHHHHHHHHHHCCH
INAVSGVSGAGRKATLTSSFCEVSLNAYGVFNHRHQPEIATHLGTEVIFTPHLGNFKRGI
HHHHCCCCCCCCEEEEEHHHHEEEEEEEEEECCCCCCHHHHHCCCEEEEECCCCCCHHHH
LATITAKLKTGVSDEQIRVAYQHAYADKPLVRVYEQGLPSIKAVEFTPYCDIGFVTKNGH
HHHHHHHHHCCCCCHHEEEEEHHHHCCCHHHHHHHCCCCCEEEEEECCCCCEEEEECCCE
IIIIGAEDNLLKGAAAQAVQCANIRYGLTETLGLL
EEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHCCC
>Mature Secondary Structure
MQKAIIIGASGYTGAELARLLIKHPEFELTGLYVSRQSQDANKCISDIYPQLKHLVDLPL
CCCEEEEECCCCCHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCC
QPLPEQLTQLAQQADLVFLATAHEVSHDLAPIFLQNQCKVFDLSGAFRVNNAAFYRTFYG
CCCHHHHHHHHHHCCEEEEEEHHHHCCCCCCEEECCCCEEEECCCCEEECCEEEEEEECC
FEHQHPELLTQAVYGLAEWNAHQIKQTDLVAVAGCYPTVSQLSLKPLIAHNLLDLTQLPV
CCCCCHHHHHHHHHHHHCCCHHHCCCCCEEEEECCCCCHHHHCCCHHHHHHHHHHHHCCH
INAVSGVSGAGRKATLTSSFCEVSLNAYGVFNHRHQPEIATHLGTEVIFTPHLGNFKRGI
HHHHCCCCCCCCEEEEEHHHHEEEEEEEEEECCCCCCHHHHHCCCEEEEECCCCCCHHHH
LATITAKLKTGVSDEQIRVAYQHAYADKPLVRVYEQGLPSIKAVEFTPYCDIGFVTKNGH
HHHHHHHHHCCCCCHHEEEEEHHHHCCCHHHHHHHCCCCCEEEEEECCCCCEEEEECCCE
IIIIGAEDNLLKGAAAQAVQCANIRYGLTETLGLL
EEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100