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The map label for this gene is prmA

Identifier: 15602953

GI number: 15602953

Start: 1283903

End: 1284784

Strand: Reverse

Name: prmA

Synonym: PM1088

Alternate gene names: 15602953

Gene position: 1284784-1283903 (Counterclockwise)

Preceding gene: 15602954

Following gene: 15602952

Centisome position: 56.91

GC content: 42.74

Gene sequence:

>882_bases
ATGGCTTGGATCCAAATTCGTATTAATAGTACTAATACACAAGCAGAACAGATGAGCGATTACTTAGCCGAAATTGGTGC
GGTGTCGGTGACATTTATGGACAGCCAAGATACTCCTATTTTTGAACCGCTTCCAGGGGAAACTCGTTTGTGGGGGAATA
CGGATGTGGTGGCGTTATTTGATGCAGAAACAGACATGCAACAGATTGTGGATTTACTCAAAGAAGCGCAATATCTCGTT
GAAAGTTCTGTATATAAAATTGAACAAATCGAAGATAAAGATTGGGAGAGAGAATGGATGGATAACTTTCATCCTATGCG
ATTTGGTAAACGTTTATGGATTTGTCCAAGTTGGCGTGAGGTACCAGATGAAAACGCTACCAATGTAATGCTCGATCCTG
GTTTAGCGTTTGGTACAGGTACTCATCCAACGACCGCATTGTGTTTAGAATGGTTAGATAGCCTTGATTTACAAGATAAA
ACCGTGATTGATTTTGGTTGCGGTTCGGGCATTTTAGCGATTGCCGCCCTAAAACTGGGCGCGAAAAGTGCGGTGGGCAT
TGATATTGATCCACAAGCGATTTTAGCCAGCCGCAATAATGCGGAGCAAAATGGCGTAGCCGACAGACTGCAATTATTCT
TATCTGAAGATAAGCCGGCTGATTTAAAAGCAGATGTGGTGGTAGCCAATATTCTTGCAGGACCATTAAAAGAACTTTAT
CCAGTGATTCGCCAATTAGTGAAACCAAATGGTGTTCTAGGACTATCAGGCATTTTAGCAACTCAAGCATCGTCCGTTTG
TGATGCCTACGCGCAATCTTTTGTCCTTGAACCCGTAGAAGAACGCGAAGAATGGTGCCGTATTACGGGAAAATTGCAAT
AG

Upstream 100 bases:

>100_bases
TGCCCTTATTATTTTGCGTAAAAACCTGCAACAATGTATCGTGACACGATACAATACACGACAGGTTATGATTTTATTAA
CAGATTGAGGAAAATTGATT

Downstream 100 bases:

>100_bases
AGGAACCGCGTCATTTAGCGGAAATATAAAAGCGAGAAAAATTATTTTGCTTATTTTATGAGCAAATGGAGTGTATTGGA
CAATAAACAAACGATTGTTA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MAWIQIRINSTNTQAEQMSDYLAEIGAVSVTFMDSQDTPIFEPLPGETRLWGNTDVVALFDAETDMQQIVDLLKEAQYLV
ESSVYKIEQIEDKDWEREWMDNFHPMRFGKRLWICPSWREVPDENATNVMLDPGLAFGTGTHPTTALCLEWLDSLDLQDK
TVIDFGCGSGILAIAALKLGAKSAVGIDIDPQAILASRNNAEQNGVADRLQLFLSEDKPADLKADVVVANILAGPLKELY
PVIRQLVKPNGVLGLSGILATQASSVCDAYAQSFVLEPVEEREEWCRITGKLQ

Sequences:

>Translated_293_residues
MAWIQIRINSTNTQAEQMSDYLAEIGAVSVTFMDSQDTPIFEPLPGETRLWGNTDVVALFDAETDMQQIVDLLKEAQYLV
ESSVYKIEQIEDKDWEREWMDNFHPMRFGKRLWICPSWREVPDENATNVMLDPGLAFGTGTHPTTALCLEWLDSLDLQDK
TVIDFGCGSGILAIAALKLGAKSAVGIDIDPQAILASRNNAEQNGVADRLQLFLSEDKPADLKADVVVANILAGPLKELY
PVIRQLVKPNGVLGLSGILATQASSVCDAYAQSFVLEPVEEREEWCRITGKLQ
>Mature_292_residues
AWIQIRINSTNTQAEQMSDYLAEIGAVSVTFMDSQDTPIFEPLPGETRLWGNTDVVALFDAETDMQQIVDLLKEAQYLVE
SSVYKIEQIEDKDWEREWMDNFHPMRFGKRLWICPSWREVPDENATNVMLDPGLAFGTGTHPTTALCLEWLDSLDLQDKT
VIDFGCGSGILAIAALKLGAKSAVGIDIDPQAILASRNNAEQNGVADRLQLFLSEDKPADLKADVVVANILAGPLKELYP
VIRQLVKPNGVLGLSGILATQASSVCDAYAQSFVLEPVEEREEWCRITGKLQ

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=291, Percent_Identity=72.8522336769759, Blast_Score=418, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_PASMU (Q9CLW2)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246025.1
- ProteinModelPortal:   Q9CLW2
- SMR:   Q9CLW2
- PRIDE:   Q9CLW2
- GeneID:   1244435
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1088
- NMPDR:   fig|272843.1.peg.1088
- HOGENOM:   HBG584653
- OMA:   EREEWCR
- ProtClustDB:   PRK00517
- BioCyc:   PMUL272843:PM1088-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32474; Mature: 32343

Theoretical pI: Translated: 4.11; Mature: 4.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWIQIRINSTNTQAEQMSDYLAEIGAVSVTFMDSQDTPIFEPLPGETRLWGNTDVVALF
CEEEEEEECCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCEECCCCCEEEEE
DAETDMQQIVDLLKEAQYLVESSVYKIEQIEDKDWEREWMDNFHPMRFGKRLWICPSWRE
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHCCEEEECCCHHH
VPDENATNVMLDPGLAFGTGTHPTTALCLEWLDSLDLQDKTVIDFGCGSGILAIAALKLG
CCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHC
AKSAVGIDIDPQAILASRNNAEQNGVADRLQLFLSEDKPADLKADVVVANILAGPLKELY
CCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
PVIRQLVKPNGVLGLSGILATQASSVCDAYAQSFVLEPVEEREEWCRITGKLQ
HHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AWIQIRINSTNTQAEQMSDYLAEIGAVSVTFMDSQDTPIFEPLPGETRLWGNTDVVALF
EEEEEEECCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCEECCCCCEEEEE
DAETDMQQIVDLLKEAQYLVESSVYKIEQIEDKDWEREWMDNFHPMRFGKRLWICPSWRE
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHCCEEEECCCHHH
VPDENATNVMLDPGLAFGTGTHPTTALCLEWLDSLDLQDKTVIDFGCGSGILAIAALKLG
CCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHC
AKSAVGIDIDPQAILASRNNAEQNGVADRLQLFLSEDKPADLKADVVVANILAGPLKELY
CCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
PVIRQLVKPNGVLGLSGILATQASSVCDAYAQSFVLEPVEEREEWCRITGKLQ
HHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100