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The map label for this gene is mtlR [H]

Identifier: 15602928

GI number: 15602928

Start: 1252499

End: 1253017

Strand: Direct

Name: mtlR [H]

Synonym: PM1063

Alternate gene names: 15602928

Gene position: 1252499-1253017 (Clockwise)

Preceding gene: 15602927

Following gene: 15602930

Centisome position: 55.48

GC content: 36.8

Gene sequence:

>519_bases
GTGCAGTCAGTCGATCCCATTTATGAAAAACTCAATGAAGCCACCTCAATTCGTGGTTTCATTACGGCTTCTGTCGCGAT
TTTTGACGAAGCGGTTGATAAACTTATTAATCGCGTTTTTCGTAAAACAGATTTTGCCGTCAAATCTGTAGTTGACTCAT
TATTATCTAATTCTGGACCGCTCTGCGATTTATCGATTCGTTTAAAAGTCTTATTAGGTTTAGGGATTATCGAGCATCAT
GTGTTTAGCGATATCAGCCATTTTATTGAGATTAAAGAAAAGCTGAATAACGATGAAAAAGAATACGATTTTGCCGATCT
CATTATTATTGATTTTATCCAACAGTTAAGCTGTCAAAATGATAAATCCTTGCTCAATTTTCCGATGGAAAAAGACGAAA
ACCCCGACTCACTACTCTATCAAGTCAAAGCCTTACGTCGAGAAAAATTGATTCGTTCTTATCTCACCTTGGCAATCACT
GAAATTTACGAGCAACTCCAAATCGAAAGTCCATTGTGA

Upstream 100 bases:

>100_bases
AGAATCAAACATTGTGCAACAAATCGTAACTGCTTATAATGCCTTGCAAAAAAACTAAAGTGCCAATGCGGTCTTAATTC
GGTCTAGAAAAGGATAACGA

Downstream 100 bases:

>100_bases
AGCAAACATAAAAAATGCGATGAAATGAATTCATCGCATTTTGTTCAAAAGAAATGAAAATTATTTACCCTCCCAAGCAT
GAATTGCTTTAGCACGGACA

Product: mannitol repressor protein

Products: NA

Alternate protein names: Mannitol repressor protein [H]

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MQSVDPIYEKLNEATSIRGFITASVAIFDEAVDKLINRVFRKTDFAVKSVVDSLLSNSGPLCDLSIRLKVLLGLGIIEHH
VFSDISHFIEIKEKLNNDEKEYDFADLIIIDFIQQLSCQNDKSLLNFPMEKDENPDSLLYQVKALRREKLIRSYLTLAIT
EIYEQLQIESPL

Sequences:

>Translated_172_residues
MQSVDPIYEKLNEATSIRGFITASVAIFDEAVDKLINRVFRKTDFAVKSVVDSLLSNSGPLCDLSIRLKVLLGLGIIEHH
VFSDISHFIEIKEKLNNDEKEYDFADLIIIDFIQQLSCQNDKSLLNFPMEKDENPDSLLYQVKALRREKLIRSYLTLAIT
EIYEQLQIESPL
>Mature_172_residues
MQSVDPIYEKLNEATSIRGFITASVAIFDEAVDKLINRVFRKTDFAVKSVVDSLLSNSGPLCDLSIRLKVLLGLGIIEHH
VFSDISHFIEIKEKLNNDEKEYDFADLIIIDFIQQLSCQNDKSLLNFPMEKDENPDSLLYQVKALRREKLIRSYLTLAIT
EIYEQLQIESPL

Specific function: Acts as a repressor of the mtlAD operon [H]

COG id: COG3722

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli yggD [H]

Homologues:

Organism=Escherichia coli, GI1790029, Length=163, Percent_Identity=35.5828220858896, Blast_Score=110, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007761 [H]

Pfam domain/function: PF05068 MtlR [H]

EC number: NA

Molecular weight: Translated: 19737; Mature: 19737

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSVDPIYEKLNEATSIRGFITASVAIFDEAVDKLINRVFRKTDFAVKSVVDSLLSNSGP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LCDLSIRLKVLLGLGIIEHHVFSDISHFIEIKEKLNNDEKEYDFADLIIIDFIQQLSCQN
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
DKSLLNFPMEKDENPDSLLYQVKALRREKLIRSYLTLAITEIYEQLQIESPL
CHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQSVDPIYEKLNEATSIRGFITASVAIFDEAVDKLINRVFRKTDFAVKSVVDSLLSNSGP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LCDLSIRLKVLLGLGIIEHHVFSDISHFIEIKEKLNNDEKEYDFADLIIIDFIQQLSCQN
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
DKSLLNFPMEKDENPDSLLYQVKALRREKLIRSYLTLAITEIYEQLQIESPL
CHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]