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The map label for this gene is ntdB [H]

Identifier: 15602912

GI number: 15602912

Start: 1235196

End: 1236026

Strand: Direct

Name: ntdB [H]

Synonym: PM1047

Alternate gene names: 15602912

Gene position: 1235196-1236026 (Clockwise)

Preceding gene: 15602905

Following gene: 15602917

Centisome position: 54.72

GC content: 41.28

Gene sequence:

>831_bases
ATGACATTGGCAAAAGACAAACTACCGGCAACCTTTCCACAACCGACTGAAGTACAGTATTTGGTTTGTTGTGATATGGA
TGAAACCTATATTCCTTATCATCCCGACAATCAAGTGACAAGCGGGATTACCGAATTAGAGCATTTCCTTTTAGAAGAAG
GGAAGAAAAAAGGCATCCTGTTAGGTTGGATAACAGGCACAAATAAGACCTCCGCGTTACGCAAAGCAAAGCGTACCATT
TCACAAAGTCCACACTTTTTATGTTGTAGTTTAGGAACCGAGTTTTATTGGATAACGCAAGGGGAATTTGTGCCATCGAC
AACTTGGCAACAACGTATTGCTACTTCTGGTTATCAGCAACAAAAAGTTGATCAGATCGTCGAACAAATTCTTGCTCAAG
GTATCAGATTAGATAGACAGCCTGAAGATTATCAAGGTCCCTATAAAACCAGTTTTTATTATTTGATCAGAGATGAGATG
GAAAAAGACATTGCTTGGATACGCTCACTCGCCGAACAAGCACAACTGAGAGTACTCATCACGAGAGCAAATCCTGCTGC
CGGTGATCCTGAAAACAGTTATGATGTGGACTTTATTCCAAAATGCTGTGGTAAAGATCAAGCAATACTCTTTTTAATGG
AAGAATTGAAACTCGACAAACAGCAGGTTTTAGCATTTGGTGACAGTGCCAATGATTTTGCTATGTTTGCTGTGGCTGGG
AATGGCTATTTGGTAGCCAATGCAGATAAGCATGCGATTGAGCGGTATGGCAAGTGCCTAGATAAGCCTTACTGTCACGG
CATCTTGAGTGTTCTTCGTCAATTGCCGTAA

Upstream 100 bases:

>100_bases
TAGCAGTGCAAAAAACAAGCGGTTTTTCACCTCATATCGTAGCTTTTCAGTTATGATAGGCGAAATTGTTTATGATCAGC
ACGTGATCTTAGGAGGCATG

Downstream 100 bases:

>100_bases
ATATAATAAAGGCGAACTGAGGGTTCGCCTTTATTATGACTTATGCACTTACTCCAGTTCAGGAAAGAGCATCTTAATCA
CATTCTGAGTTAAACGACGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MTLAKDKLPATFPQPTEVQYLVCCDMDETYIPYHPDNQVTSGITELEHFLLEEGKKKGILLGWITGTNKTSALRKAKRTI
SQSPHFLCCSLGTEFYWITQGEFVPSTTWQQRIATSGYQQQKVDQIVEQILAQGIRLDRQPEDYQGPYKTSFYYLIRDEM
EKDIAWIRSLAEQAQLRVLITRANPAAGDPENSYDVDFIPKCCGKDQAILFLMEELKLDKQQVLAFGDSANDFAMFAVAG
NGYLVANADKHAIERYGKCLDKPYCHGILSVLRQLP

Sequences:

>Translated_276_residues
MTLAKDKLPATFPQPTEVQYLVCCDMDETYIPYHPDNQVTSGITELEHFLLEEGKKKGILLGWITGTNKTSALRKAKRTI
SQSPHFLCCSLGTEFYWITQGEFVPSTTWQQRIATSGYQQQKVDQIVEQILAQGIRLDRQPEDYQGPYKTSFYYLIRDEM
EKDIAWIRSLAEQAQLRVLITRANPAAGDPENSYDVDFIPKCCGKDQAILFLMEELKLDKQQVLAFGDSANDFAMFAVAG
NGYLVANADKHAIERYGKCLDKPYCHGILSVLRQLP
>Mature_275_residues
TLAKDKLPATFPQPTEVQYLVCCDMDETYIPYHPDNQVTSGITELEHFLLEEGKKKGILLGWITGTNKTSALRKAKRTIS
QSPHFLCCSLGTEFYWITQGEFVPSTTWQQRIATSGYQQQKVDQIVEQILAQGIRLDRQPEDYQGPYKTSFYYLIRDEME
KDIAWIRSLAEQAQLRVLITRANPAAGDPENSYDVDFIPKCCGKDQAILFLMEELKLDKQQVLAFGDSANDFAMFAVAGN
GYLVANADKHAIERYGKCLDKPYCHGILSVLRQLP

Specific function: Part of the ntdABC operon that biosynthesizes the NTD (3,3'-neotrehalosadiamine) antibiotic [H]

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006379
- InterPro:   IPR000150
- InterPro:   IPR006380 [H]

Pfam domain/function: PF05116 S6PP [H]

EC number: NA

Molecular weight: Translated: 31319; Mature: 31188

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLAKDKLPATFPQPTEVQYLVCCDMDETYIPYHPDNQVTSGITELEHFLLEEGKKKGIL
CCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEE
LGWITGTNKTSALRKAKRTISQSPHFLCCSLGTEFYWITQGEFVPSTTWQQRIATSGYQQ
EEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCCCHHHHHHHHCCHHH
QKVDQIVEQILAQGIRLDRQPEDYQGPYKTSFYYLIRDEMEKDIAWIRSLAEQAQLRVLI
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCEEEEEE
TRANPAAGDPENSYDVDFIPKCCGKDQAILFLMEELKLDKQQVLAFGDSANDFAMFAVAG
EECCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHCCCHHHHEEECCCCCCEEEEEEEC
NGYLVANADKHAIERYGKCLDKPYCHGILSVLRQLP
CCEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLAKDKLPATFPQPTEVQYLVCCDMDETYIPYHPDNQVTSGITELEHFLLEEGKKKGIL
CCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEE
LGWITGTNKTSALRKAKRTISQSPHFLCCSLGTEFYWITQGEFVPSTTWQQRIATSGYQQ
EEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCCCHHHHHHHHCCHHH
QKVDQIVEQILAQGIRLDRQPEDYQGPYKTSFYYLIRDEMEKDIAWIRSLAEQAQLRVLI
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCEEEEEE
TRANPAAGDPENSYDVDFIPKCCGKDQAILFLMEELKLDKQQVLAFGDSANDFAMFAVAG
EECCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHCCCHHHHEEECCCCCCEEEEEEEC
NGYLVANADKHAIERYGKCLDKPYCHGILSVLRQLP
CCEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]