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The map label for this gene is mglC [H]

Identifier: 15602905

GI number: 15602905

Start: 1223925

End: 1224935

Strand: Direct

Name: mglC [H]

Synonym: PM1040

Alternate gene names: 15602905

Gene position: 1223925-1224935 (Clockwise)

Preceding gene: 15602904

Following gene: 15602912

Centisome position: 54.22

GC content: 42.43

Gene sequence:

>1011_bases
ATGGCTGCATTAAAACAAAATAAATCCCTTGATTTCTTTAAACAAAATGCAATCTACTTTGTATTATTAATTTTACTCGG
GATCATCATTGTTCAAGACCCAACATTCTTGAACTTACGAAACTTCAGTAACATTTTAACGCAATCTTCCGTACGCTTAA
TCATCGCGCTGGGTGTAGCCGGCTTACTTGTCACACAAGGGACAGACTTATCTGCCGGTCGCCAAGTCGGTTTAGCGGCG
GTTATTTCAGCGACCTTGTTACAAGCCATGGACAACTTTAACCGCGTTTTCCCGGATTTACCTGAGCTCCCAATTCCGGT
TGTAATTTTAACTGTTTGTGCGATTGGTGCAGTCATCGGTTTAGTAAATGGTTTAGTTATTGCTTACTTAAACGTAACAC
CATTTATTGCCACCATGGGGACCATGATTATCGTTTATGGGATTAACTCACTTTACTATGATGCGGTAGGAGGATCGCCA
ATTGCAGGCTTTAACGAAACCTTCTCAACGTTTGCACAAGGTTTCTTTAAATTCGGTTCCTTCAAACTGTCCTATATCAC
GATTTATGCTGCTGTTGCGACCTTCTTAGTGTGGGTATTGTGGAATAAAACGCGCTTTGGTAAAAATATCTTTGCTATCG
GTGGTAACCCAGAAGCGGCTCGTGTATCTGGCGTTAACGTCGCACGTAACTTAGTGGTTATCTATATGATCGCGGGGATG
TTCTACGGTTTTGGTGGGATGTTAGAAGCCGGTCGTATCGGTTCTGCCACTAATAACTTAGGTTTCATGTATGAATTAGA
TGCGATTGCTGCCTGTGTAGTAGGGGGCGTCTCATTCGCCGGTGGTGTGGGTACGGTTATTGGTGTGGTAACTGGGGTAA
TTATCTTTACCGTCATCAACTACGGCTTAACCTATATCGGTGTTAACCCATATTGGCAATATATCATCAAAGGTAGCATC
ATCATTCTTGCGGTGGCTATCGACTCACTCAAATACGCGAAGAAAAAATAA

Upstream 100 bases:

>100_bases
TAAAGTCGCAGGTATCGTGAATACTGCTGAAACCTCACAAGAAGAAATTTTACAGCTCGCTGCAAAATATTTATAAAACA
CAGAATTAAGGAAATAAATT

Downstream 100 bases:

>100_bases
AAAGGCGTATCGCACTAGCACAAAAAAGGCGATTCTCAGAATCGCCTTTATTTTCTATCGAAGCGTCGTAAAAGAGACGA
ACGCCACACAACTCATCACA

Product: beta-methylgalactoside transporter inner membrane component

Products: ADP; phosphate; beta-D-galactose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MAALKQNKSLDFFKQNAIYFVLLILLGIIIVQDPTFLNLRNFSNILTQSSVRLIIALGVAGLLVTQGTDLSAGRQVGLAA
VISATLLQAMDNFNRVFPDLPELPIPVVILTVCAIGAVIGLVNGLVIAYLNVTPFIATMGTMIIVYGINSLYYDAVGGSP
IAGFNETFSTFAQGFFKFGSFKLSYITIYAAVATFLVWVLWNKTRFGKNIFAIGGNPEAARVSGVNVARNLVVIYMIAGM
FYGFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFAGGVGTVIGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGSI
IILAVAIDSLKYAKKK

Sequences:

>Translated_336_residues
MAALKQNKSLDFFKQNAIYFVLLILLGIIIVQDPTFLNLRNFSNILTQSSVRLIIALGVAGLLVTQGTDLSAGRQVGLAA
VISATLLQAMDNFNRVFPDLPELPIPVVILTVCAIGAVIGLVNGLVIAYLNVTPFIATMGTMIIVYGINSLYYDAVGGSP
IAGFNETFSTFAQGFFKFGSFKLSYITIYAAVATFLVWVLWNKTRFGKNIFAIGGNPEAARVSGVNVARNLVVIYMIAGM
FYGFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFAGGVGTVIGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGSI
IILAVAIDSLKYAKKK
>Mature_335_residues
AALKQNKSLDFFKQNAIYFVLLILLGIIIVQDPTFLNLRNFSNILTQSSVRLIIALGVAGLLVTQGTDLSAGRQVGLAAV
ISATLLQAMDNFNRVFPDLPELPIPVVILTVCAIGAVIGLVNGLVIAYLNVTPFIATMGTMIIVYGINSLYYDAVGGSPI
AGFNETFSTFAQGFFKFGSFKLSYITIYAAVATFLVWVLWNKTRFGKNIFAIGGNPEAARVSGVNVARNLVVIYMIAGMF
YGFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFAGGVGTVIGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGSII
ILAVAIDSLKYAKKK

Specific function: Part of the binding-protein-dependent transport system for galactoside. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4211

COG function: function code G; ABC-type glucose/galactose transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788471, Length=336, Percent_Identity=79.4642857142857, Blast_Score=470, Evalue=1e-134,
Organism=Escherichia coli, GI1790191, Length=332, Percent_Identity=34.9397590361446, Blast_Score=161, Evalue=6e-41,
Organism=Escherichia coli, GI1790524, Length=320, Percent_Identity=31.25, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI145693152, Length=327, Percent_Identity=30.8868501529052, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789992, Length=128, Percent_Identity=46.875, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1788896, Length=337, Percent_Identity=30.5637982195846, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787793, Length=305, Percent_Identity=27.5409836065574, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082395, Length=301, Percent_Identity=28.9036544850498, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787794, Length=287, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI145693214, Length=269, Percent_Identity=31.2267657992565, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 35887; Mature: 35756

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAALKQNKSLDFFKQNAIYFVLLILLGIIIVQDPTFLNLRNFSNILTQSSVRLIIALGVA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
GLLVTQGTDLSAGRQVGLAAVISATLLQAMDNFNRVFPDLPELPIPVVILTVCAIGAVIG
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
LVNGLVIAYLNVTPFIATMGTMIIVYGINSLYYDAVGGSPIAGFNETFSTFAQGFFKFGS
HHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHCC
FKLSYITIYAAVATFLVWVLWNKTRFGKNIFAIGGNPEAARVSGVNVARNLVVIYMIAGM
CHHHHHHHHHHHHHHHHHHHHCCHHCCCEEEEECCCCCCCEECCHHHHHHHHHHHHHHHH
FYGFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFAGGVGTVIGVVTGVIIFTVIN
HHCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
YGLTYIGVNPYWQYIIKGSIIILAVAIDSLKYAKKK
CCCEEEECCHHHHHHHCCCCEEEEEHHHHHHHHCCC
>Mature Secondary Structure 
AALKQNKSLDFFKQNAIYFVLLILLGIIIVQDPTFLNLRNFSNILTQSSVRLIIALGVA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
GLLVTQGTDLSAGRQVGLAAVISATLLQAMDNFNRVFPDLPELPIPVVILTVCAIGAVIG
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
LVNGLVIAYLNVTPFIATMGTMIIVYGINSLYYDAVGGSPIAGFNETFSTFAQGFFKFGS
HHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHCC
FKLSYITIYAAVATFLVWVLWNKTRFGKNIFAIGGNPEAARVSGVNVARNLVVIYMIAGM
CHHHHHHHHHHHHHHHHHHHHCCHHCCCEEEEECCCCCCCEECCHHHHHHHHHHHHHHHH
FYGFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFAGGVGTVIGVVTGVIIFTVIN
HHCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
YGLTYIGVNPYWQYIIKGSIIILAVAIDSLKYAKKK
CCCEEEECCHHHHHHHCCCCEEEEEHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; beta-D-galactose [Periplasm]; H2O [C]

Specific reaction: ATP + beta-D-galactose [Periplasm] + H2O = ADP + phosphate + beta-D-galactose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]