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The map label for this gene is tmcA [H]

Identifier: 15602908

GI number: 15602908

Start: 1230588

End: 1232543

Strand: Reverse

Name: tmcA [H]

Synonym: PM1043

Alternate gene names: 15602908

Gene position: 1232543-1230588 (Counterclockwise)

Preceding gene: 15602909

Following gene: 15602907

Centisome position: 54.6

GC content: 43.81

Gene sequence:

>1956_bases
ATGAATCGGGTAAATAAGCAAAGAAAAGTACAATGTTGGGTGGGGGAGAATGCTACATTATTTCCCCCACTCGCACGCTT
ATCTGGAATAAAAAGTGCGGTATGGATTGGCGATGATTTACCGCCTTTTTTGTCTTTTGCTCATTTCGATTTCAAGCAAG
CAAAAAACATGTTGGGGCAAGAGTTTGCCTTGATTGTCTATGATGCAAGGGGAGGGCTGAATCTTGATGCCTTAGCTATC
GCCAGTGGCACTTTGCAACAAGACGGTGTGTTGCTGATTTTATTACCACAATGGGCGATGCTGAGCACTTGGCAAGATCC
TGATTCCGTCCGTTGGTCTGGTGAAAATGATCCTATTTTGACACCGCACTTTCTACATTATTTTCAACAAAAAGTACGAG
ACTACGGCTTTCCGGTTTATCATACTTTTTTCCCTTCGCTATCATTGCCGGATAAATCAACCAGTGCGGTCGATTTTCAA
TCAGAACCGACAGTGGAACAAGCACAGTTACTGCACCGTATCAACAAGGCTACTGAAGCGGTATTGATTGTGACGGCGAA
GCGGGGTCGAGGAAAATCGGCGCTAGCAGGTTTTTGGGCAAGGCAGTTGAAGCAACAAAACCAAACATTGATATTAACTG
CACCGAATAAAGCGGCTGTCAGGATTTTACAAGCGTTTGCTAATACGGCGTTAGATTTCAAGTCACCAGATTTACTTTGT
GAGCAAATTGCACAAGATCCCCATGCGTTTGCTGATAAATGGTTATTGATTGATGAAGCGGCTATGCTCCCTTTAAGTTT
GTTAGAACTGCTGACATCAACCTTTAAAGGCATACTCTGTACCACTACGATACAAAGTTACGAAGGGACCGGGCGTGGTT
TTTTACTCAAATTTTTAGCCAATTTAGACCGCACTTTTGCGCATTTTGAGCTTCACCAGCCTCTACGTTGGCAAGTTGAT
GATAAGTTAGAAGCCTTTATGGATGATCTCTTATTGCTACATGCGGAAGATTTGCCTTTTGCCCCATTGGCGTCAGCTGA
AGGCGTTCAATTTCAGCGCTATTCACAACATACATTATATCAGCAACAAAAAATTGCTCCGCTTTATGGTTTACTGACGC
GTGCCCATTACCGTACGTCACCACTGGATTTACGCCGTTTGTTTGATGCGCCAAATCAACATTTTTATTTAGCACAAAAA
GACGAACATCTTCTTGGTGCCGCTTGGCTTGTGCAAGAGGGAAGTCTGCAATCAGAACAACTTATTGGTGAGATTGAGCG
CGGTTTGCGCCGTCCTCGTGGCAATTTAGTGCCTCAATTACTGTGTTTTCAAGCGCATTTACCGCAAGCCTGCCGTTTAT
CCTCATTGCGGATTTCCCGTATTGCTGTTCAGCCAAATTGGCAACAGCAAGGTATTGGGCAACAGTTAGTCAAAAATATT
TGCCAAGATGCACAGGTGGATTTTTTGTCCGTCAGTTTTGGTTACACCACTAAGTTGGCTGCATTTTGGCAAAAGTGCGG
TTTTTTATTGGTGCATTTAGGTGAACAGAAAGAAGCCAGTAGCGGTTGTTACTCTGTAATCGGCTTAAAACCGTTGTCGT
CCGCAGGGATAAGCTTTTGTCAGCAAGCGTACCAACAGTTCCAACGTAATCTCAGTTTATCGCGACACTCCCTCGCGACG
GCGTTCCCTTCTTTGCCCTCCACATGGCAATTAGATCCGCAAGATTGGCGTGCATTAGTACATTTTGCTTATTTTCAAGG
CTCATTTACAGCCGCCTTACCTGCGATACAACGTTTGTTGGCACAAACTAACAGGTGCATTTGTCCGTTATTATCTGCCC
TGTTACAACCGTCATCAAACGAGATGAAATTTGTGGGAGGCAAGAAAAATGGGATAAAAATATGCCGTGAGGAAGTCAAG
AAATTGTTGCAAAATCATACAGCCGTTTTATCATAA

Upstream 100 bases:

>100_bases
AATACTTGGTCAGCCAGAGCCGATGTATAAACCTAAACGCGATATCAGTATTGATTGGTCACACCCGTTAGATCGTTGGT
AATAGCACGATGAAAGTAAA

Downstream 100 bases:

>100_bases
TCAAGTGGGGTGTTGAGAAGGAGCATAAAATGGAGCAGACAAAAAAGAAAGGTTTATTACGTCGCGTGTGGGACGGTTAC
AGCAAATTCTGTCAGGACAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 651; Mature: 651

Protein sequence:

>651_residues
MNRVNKQRKVQCWVGENATLFPPLARLSGIKSAVWIGDDLPPFLSFAHFDFKQAKNMLGQEFALIVYDARGGLNLDALAI
ASGTLQQDGVLLILLPQWAMLSTWQDPDSVRWSGENDPILTPHFLHYFQQKVRDYGFPVYHTFFPSLSLPDKSTSAVDFQ
SEPTVEQAQLLHRINKATEAVLIVTAKRGRGKSALAGFWARQLKQQNQTLILTAPNKAAVRILQAFANTALDFKSPDLLC
EQIAQDPHAFADKWLLIDEAAMLPLSLLELLTSTFKGILCTTTIQSYEGTGRGFLLKFLANLDRTFAHFELHQPLRWQVD
DKLEAFMDDLLLLHAEDLPFAPLASAEGVQFQRYSQHTLYQQQKIAPLYGLLTRAHYRTSPLDLRRLFDAPNQHFYLAQK
DEHLLGAAWLVQEGSLQSEQLIGEIERGLRRPRGNLVPQLLCFQAHLPQACRLSSLRISRIAVQPNWQQQGIGQQLVKNI
CQDAQVDFLSVSFGYTTKLAAFWQKCGFLLVHLGEQKEASSGCYSVIGLKPLSSAGISFCQQAYQQFQRNLSLSRHSLAT
AFPSLPSTWQLDPQDWRALVHFAYFQGSFTAALPAIQRLLAQTNRCICPLLSALLQPSSNEMKFVGGKKNGIKICREEVK
KLLQNHTAVLS

Sequences:

>Translated_651_residues
MNRVNKQRKVQCWVGENATLFPPLARLSGIKSAVWIGDDLPPFLSFAHFDFKQAKNMLGQEFALIVYDARGGLNLDALAI
ASGTLQQDGVLLILLPQWAMLSTWQDPDSVRWSGENDPILTPHFLHYFQQKVRDYGFPVYHTFFPSLSLPDKSTSAVDFQ
SEPTVEQAQLLHRINKATEAVLIVTAKRGRGKSALAGFWARQLKQQNQTLILTAPNKAAVRILQAFANTALDFKSPDLLC
EQIAQDPHAFADKWLLIDEAAMLPLSLLELLTSTFKGILCTTTIQSYEGTGRGFLLKFLANLDRTFAHFELHQPLRWQVD
DKLEAFMDDLLLLHAEDLPFAPLASAEGVQFQRYSQHTLYQQQKIAPLYGLLTRAHYRTSPLDLRRLFDAPNQHFYLAQK
DEHLLGAAWLVQEGSLQSEQLIGEIERGLRRPRGNLVPQLLCFQAHLPQACRLSSLRISRIAVQPNWQQQGIGQQLVKNI
CQDAQVDFLSVSFGYTTKLAAFWQKCGFLLVHLGEQKEASSGCYSVIGLKPLSSAGISFCQQAYQQFQRNLSLSRHSLAT
AFPSLPSTWQLDPQDWRALVHFAYFQGSFTAALPAIQRLLAQTNRCICPLLSALLQPSSNEMKFVGGKKNGIKICREEVK
KLLQNHTAVLS
>Mature_651_residues
MNRVNKQRKVQCWVGENATLFPPLARLSGIKSAVWIGDDLPPFLSFAHFDFKQAKNMLGQEFALIVYDARGGLNLDALAI
ASGTLQQDGVLLILLPQWAMLSTWQDPDSVRWSGENDPILTPHFLHYFQQKVRDYGFPVYHTFFPSLSLPDKSTSAVDFQ
SEPTVEQAQLLHRINKATEAVLIVTAKRGRGKSALAGFWARQLKQQNQTLILTAPNKAAVRILQAFANTALDFKSPDLLC
EQIAQDPHAFADKWLLIDEAAMLPLSLLELLTSTFKGILCTTTIQSYEGTGRGFLLKFLANLDRTFAHFELHQPLRWQVD
DKLEAFMDDLLLLHAEDLPFAPLASAEGVQFQRYSQHTLYQQQKIAPLYGLLTRAHYRTSPLDLRRLFDAPNQHFYLAQK
DEHLLGAAWLVQEGSLQSEQLIGEIERGLRRPRGNLVPQLLCFQAHLPQACRLSSLRISRIAVQPNWQQQGIGQQLVKNI
CQDAQVDFLSVSFGYTTKLAAFWQKCGFLLVHLGEQKEASSGCYSVIGLKPLSSAGISFCQQAYQQFQRNLSLSRHSLAT
AFPSLPSTWQLDPQDWRALVHFAYFQGSFTAALPAIQRLLAQTNRCICPLLSALLQPSSNEMKFVGGKKNGIKICREEVK
KLLQNHTAVLS

Specific function: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) [H]

COG id: COG1444

COG function: function code R; Predicted P-loop ATPase fused to an acetyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI221316723, Length=375, Percent_Identity=24, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI221316741, Length=375, Percent_Identity=24, Blast_Score=88, Evalue=3e-17,
Organism=Escherichia coli, GI1788818, Length=600, Percent_Identity=39.8333333333333, Blast_Score=363, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17507621, Length=265, Percent_Identity=27.9245283018868, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24640662, Length=362, Percent_Identity=24.585635359116, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013562
- InterPro:   IPR007807 [H]

Pfam domain/function: PF08351 DUF1726; PF05127 DUF699 [H]

EC number: NA

Molecular weight: Translated: 73196; Mature: 73196

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRVNKQRKVQCWVGENATLFPPLARLSGIKSAVWIGDDLPPFLSFAHFDFKQAKNMLGQ
CCCCCCCCEEEEEECCCCCCCCCHHHHHCCCCEEEECCCCCHHHHHHHCCHHHHHHHCCC
EFALIVYDARGGLNLDALAIASGTLQQDGVLLILLPQWAMLSTWQDPDSVRWSGENDPIL
CEEEEEEECCCCCCCHHHHHCCCCCCCCCEEEEECCCCHHHHCCCCCCCEEECCCCCCCC
TPHFLHYFQQKVRDYGFPVYHTFFPSLSLPDKSTSAVDFQSEPTVEQAQLLHRINKATEA
CHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCE
VLIVTAKRGRGKSALAGFWARQLKQQNQTLILTAPNKAAVRILQAFANTALDFKSPDLLC
EEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHH
EQIAQDPHAFADKWLLIDEAAMLPLSLLELLTSTFKGILCTTTIQSYEGTGRGFLLKFLA
HHHHCCCHHHHCCEEEEHHHHHHHHHHHHHHHHHHCCEEEEEEHHHCCCCCHHHHHHHHH
NLDRTFAHFELHQPLRWQVDDKLEAFMDDLLLLHAEDLPFAPLASAEGVQFQRYSQHTLY
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
QQQKIAPLYGLLTRAHYRTSPLDLRRLFDAPNQHFYLAQKDEHLLGAAWLVQEGSLQSEQ
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEECCCCCHHHHHHEEECCCCCHHH
LIGEIERGLRRPRGNLVPQLLCFQAHLPQACRLSSLRISRIAVQPNWQQQGIGQQLVKNI
HHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHCEEEEEEECCCHHHCCCHHHHHHHH
CQDAQVDFLSVSFGYTTKLAAFWQKCGFLLVHLGEQKEASSGCYSVIGLKPLSSAGISFC
HCCCCCEEEEEECCHHHHHHHHHHHHCEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHH
QQAYQQFQRNLSLSRHSLATAFPSLPSTWQLDPQDWRALVHFAYFQGSFTAALPAIQRLL
HHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AQTNRCICPLLSALLQPSSNEMKFVGGKKNGIKICREEVKKLLQNHTAVLS
HHCCCCHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNRVNKQRKVQCWVGENATLFPPLARLSGIKSAVWIGDDLPPFLSFAHFDFKQAKNMLGQ
CCCCCCCCEEEEEECCCCCCCCCHHHHHCCCCEEEECCCCCHHHHHHHCCHHHHHHHCCC
EFALIVYDARGGLNLDALAIASGTLQQDGVLLILLPQWAMLSTWQDPDSVRWSGENDPIL
CEEEEEEECCCCCCCHHHHHCCCCCCCCCEEEEECCCCHHHHCCCCCCCEEECCCCCCCC
TPHFLHYFQQKVRDYGFPVYHTFFPSLSLPDKSTSAVDFQSEPTVEQAQLLHRINKATEA
CHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCE
VLIVTAKRGRGKSALAGFWARQLKQQNQTLILTAPNKAAVRILQAFANTALDFKSPDLLC
EEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHH
EQIAQDPHAFADKWLLIDEAAMLPLSLLELLTSTFKGILCTTTIQSYEGTGRGFLLKFLA
HHHHCCCHHHHCCEEEEHHHHHHHHHHHHHHHHHHCCEEEEEEHHHCCCCCHHHHHHHHH
NLDRTFAHFELHQPLRWQVDDKLEAFMDDLLLLHAEDLPFAPLASAEGVQFQRYSQHTLY
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
QQQKIAPLYGLLTRAHYRTSPLDLRRLFDAPNQHFYLAQKDEHLLGAAWLVQEGSLQSEQ
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEECCCCCHHHHHHEEECCCCCHHH
LIGEIERGLRRPRGNLVPQLLCFQAHLPQACRLSSLRISRIAVQPNWQQQGIGQQLVKNI
HHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHCEEEEEEECCCHHHCCCHHHHHHHH
CQDAQVDFLSVSFGYTTKLAAFWQKCGFLLVHLGEQKEASSGCYSVIGLKPLSSAGISFC
HCCCCCEEEEEECCHHHHHHHHHHHHCEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHH
QQAYQQFQRNLSLSRHSLATAFPSLPSTWQLDPQDWRALVHFAYFQGSFTAALPAIQRLL
HHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AQTNRCICPLLSALLQPSSNEMKFVGGKKNGIKICREEVKKLLQNHTAVLS
HHCCCCHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]