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The map label for this gene is recG

Identifier: 15602784

GI number: 15602784

Start: 1083539

End: 1085620

Strand: Reverse

Name: recG

Synonym: PM0919

Alternate gene names: 15602784

Gene position: 1085620-1083539 (Counterclockwise)

Preceding gene: 15602785

Following gene: 15602783

Centisome position: 48.09

GC content: 42.89

Gene sequence:

>2082_bases
ATGACCATACAATTCCTCGATGCAGTCCCTTTAACGACACTTTCTGGTGTTGGGGCTGCCATTTCTGACAAGCTTGGGCG
GATTGGTATTCACAATCTCCAAGATTTGTTATTTCATTTACCGATTCGTTATGAAGATCGTACTCGAATTACGCCAATTC
ATGATCTTCGTCCTGATGCTTATGCTACCATTGAGGGGCTTGTACAAACGTGTGAAGTGCAGTTTGGTAAACGCCCAATT
TTAAATGTTTCTCTTTCGGATGGCACATCAAAAATTATGCTACGTTTTTTTAACTTCAATGCAGGCATGAAAAATAGTCT
TCAACCGGGTGCAAGAGTAAAAGCCTTTGGTGAGGTTAAACGTGGGCGTTTCATGGCAGAAATTCATCACCCGGAATATC
AAATTATTCGCGATAATGCCCCTTTAATTTTAGAAGAGACCTTGACGCCAATTTATTCTACAACAGAGGGAATAAAACAA
AATTCATTACGTAAGCTGACTGATCAAGCTTTGGCTGTGCTTGAGAATATCCAAATTGCAGAAATCTTACCTAATGAATT
TAATCCACATCCTTTTAGCTTAAAAGAGGCGATTCGTTTTTTGCATCGCCCACCGCCTGATGTATCCTTAGAAGCCTTAG
AAAAAGGAACCCACCCCGCTCAGCAACGCCTGATTTTTGAGGAATTATTGGCGCATAATTTGGCGATGCAAAAAGTGCGG
ATCGGTACACAGCAATTTTCCGCTTACCCTTTATCTTATCAGACTGATTTAAAACAGCGTTTTTTGGCACAATTACCTTT
TACACCAACAGATGCACAAGTTCGTGTTACCCAAGAGATAGAGCAAGATCTTACTCATCCTTTCCCGATGATGCGTTTAG
TTCAAGGTGATGTTGGCTCAGGTAAAACCTTGGTGGCTGCGTTAGCTGCCTTACTTGCAATAGATAATGGCAAACAAGTC
GCGCTCATGGCACCTACCGAAATTTTAGCGGAACAACATGCTACAAATTTTCGCCGTTGGTTTGAGTCCCTAGGCATTGA
AGTGGGTTGGCTTGCAGGTAAAGTCAAAGGAAAGGCGCGTCAAACAGAACTGGAAAAGATTCGAACGGGGCAAGTACAAA
TGGTCGTGGGAACCCATGCCTTATTTCAAGACGAGGTGGAATTTTCAGATTTGGCATTGGTGATCGTTGATGAACAGCAT
CGGTTTGGTGTGCATCAGCGTTTAATGCTACGAGAAAAAGGTAAACAGGCTGATCATTATCCGCACCAACTCATTATGAC
GGCGACACCGATTCCTCGCACTTTAGCCATGACGGTGTATGCGGATTTAGATACCTCGATTATTGATGAACTACCGCCAG
GACGAACACCGATTACGACCGTGGCAATTTCTGAAGAAAGACGAGCTGAAGTCATTGCTAGAGTGAATCATGCCTGTGTG
AATGAAAAACGTCAGGCATATTGGGTCTGTACATTGATTGATGAATCAGAAGTACTAGAGGCACAAGCGGCTGAGGCTAT
TGCTGAAGATCTTCGTAAAATTCTACCGCACTTACGCATTGGCTTAGTGCATGGTCGTATGAAACCGGCTGAAAAACAAG
ACATCATGCAAGCATTTAAACAGGCAGAAATTGATTTGTTAGTCGCAACAACGGTGATTGAGGTCGGTGTTGATGTGCCG
AATGCCAGCTTAATGATCATTGAAAATGCAGAACGTTTAGGTTTATCACAATTACATCAGTTACGCGGTCGAGTAGGACG
AGGGACAACCGCTTCTTTTTGTGTACTGATGTATAAGCCCCCACTAGGAAAAATTTCCCAGAAACGTTTACAAGTCCTCA
GAGATACGCAAGATGGTTTTGTTATTTCGGAAAAAGATTTAGAAATCAGAGGACCTGGCGAAGTGCTTGGTACAAAACAA
ACCGGGGTGGCCGAATTTAAGGTGGCAAATTTAATGCGCGATCGCAAAATGATTCCTACGGTGCAGTATTATGCGCGTCG
TTTGATTGTTGAGCAACCAGAAGTGGCCACCAAATTAATCCAACGTTGGATTAATCAACGGGAGATTTATACGCATGTCT
AA

Upstream 100 bases:

>100_bases
TCGTGTTGTTGACCGTAAAAGACACTAAGCATTTAGCGAATATTATTCGTAAAATCAAAGCAATTCCGGGTTTTGTTAAT
ATTGAACGTAATATCAATCA

Downstream 100 bases:

>100_bases
TTATTCCCAATTGTTACAAAATGCCACTTGGCAGCCTTCAACGGATATGCAATTACCTCTGTCGATTTCTTCTTGGCTAG
AGCTATCCACATCTTTAACT

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 693; Mature: 692

Protein sequence:

>693_residues
MTIQFLDAVPLTTLSGVGAAISDKLGRIGIHNLQDLLFHLPIRYEDRTRITPIHDLRPDAYATIEGLVQTCEVQFGKRPI
LNVSLSDGTSKIMLRFFNFNAGMKNSLQPGARVKAFGEVKRGRFMAEIHHPEYQIIRDNAPLILEETLTPIYSTTEGIKQ
NSLRKLTDQALAVLENIQIAEILPNEFNPHPFSLKEAIRFLHRPPPDVSLEALEKGTHPAQQRLIFEELLAHNLAMQKVR
IGTQQFSAYPLSYQTDLKQRFLAQLPFTPTDAQVRVTQEIEQDLTHPFPMMRLVQGDVGSGKTLVAALAALLAIDNGKQV
ALMAPTEILAEQHATNFRRWFESLGIEVGWLAGKVKGKARQTELEKIRTGQVQMVVGTHALFQDEVEFSDLALVIVDEQH
RFGVHQRLMLREKGKQADHYPHQLIMTATPIPRTLAMTVYADLDTSIIDELPPGRTPITTVAISEERRAEVIARVNHACV
NEKRQAYWVCTLIDESEVLEAQAAEAIAEDLRKILPHLRIGLVHGRMKPAEKQDIMQAFKQAEIDLLVATTVIEVGVDVP
NASLMIIENAERLGLSQLHQLRGRVGRGTTASFCVLMYKPPLGKISQKRLQVLRDTQDGFVISEKDLEIRGPGEVLGTKQ
TGVAEFKVANLMRDRKMIPTVQYYARRLIVEQPEVATKLIQRWINQREIYTHV

Sequences:

>Translated_693_residues
MTIQFLDAVPLTTLSGVGAAISDKLGRIGIHNLQDLLFHLPIRYEDRTRITPIHDLRPDAYATIEGLVQTCEVQFGKRPI
LNVSLSDGTSKIMLRFFNFNAGMKNSLQPGARVKAFGEVKRGRFMAEIHHPEYQIIRDNAPLILEETLTPIYSTTEGIKQ
NSLRKLTDQALAVLENIQIAEILPNEFNPHPFSLKEAIRFLHRPPPDVSLEALEKGTHPAQQRLIFEELLAHNLAMQKVR
IGTQQFSAYPLSYQTDLKQRFLAQLPFTPTDAQVRVTQEIEQDLTHPFPMMRLVQGDVGSGKTLVAALAALLAIDNGKQV
ALMAPTEILAEQHATNFRRWFESLGIEVGWLAGKVKGKARQTELEKIRTGQVQMVVGTHALFQDEVEFSDLALVIVDEQH
RFGVHQRLMLREKGKQADHYPHQLIMTATPIPRTLAMTVYADLDTSIIDELPPGRTPITTVAISEERRAEVIARVNHACV
NEKRQAYWVCTLIDESEVLEAQAAEAIAEDLRKILPHLRIGLVHGRMKPAEKQDIMQAFKQAEIDLLVATTVIEVGVDVP
NASLMIIENAERLGLSQLHQLRGRVGRGTTASFCVLMYKPPLGKISQKRLQVLRDTQDGFVISEKDLEIRGPGEVLGTKQ
TGVAEFKVANLMRDRKMIPTVQYYARRLIVEQPEVATKLIQRWINQREIYTHV
>Mature_692_residues
TIQFLDAVPLTTLSGVGAAISDKLGRIGIHNLQDLLFHLPIRYEDRTRITPIHDLRPDAYATIEGLVQTCEVQFGKRPIL
NVSLSDGTSKIMLRFFNFNAGMKNSLQPGARVKAFGEVKRGRFMAEIHHPEYQIIRDNAPLILEETLTPIYSTTEGIKQN
SLRKLTDQALAVLENIQIAEILPNEFNPHPFSLKEAIRFLHRPPPDVSLEALEKGTHPAQQRLIFEELLAHNLAMQKVRI
GTQQFSAYPLSYQTDLKQRFLAQLPFTPTDAQVRVTQEIEQDLTHPFPMMRLVQGDVGSGKTLVAALAALLAIDNGKQVA
LMAPTEILAEQHATNFRRWFESLGIEVGWLAGKVKGKARQTELEKIRTGQVQMVVGTHALFQDEVEFSDLALVIVDEQHR
FGVHQRLMLREKGKQADHYPHQLIMTATPIPRTLAMTVYADLDTSIIDELPPGRTPITTVAISEERRAEVIARVNHACVN
EKRQAYWVCTLIDESEVLEAQAAEAIAEDLRKILPHLRIGLVHGRMKPAEKQDIMQAFKQAEIDLLVATTVIEVGVDVPN
ASLMIIENAERLGLSQLHQLRGRVGRGTTASFCVLMYKPPLGKISQKRLQVLRDTQDGFVISEKDLEIRGPGEVLGTKQT
GVAEFKVANLMRDRKMIPTVQYYARRLIVEQPEVATKLIQRWINQREIYTHV

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain

Homologues:

Organism=Escherichia coli, GI2367254, Length=692, Percent_Identity=65.8959537572254, Blast_Score=919, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=420, Percent_Identity=37.1428571428571, Blast_Score=254, Evalue=2e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RECG_PASMU (Q9CMB4)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245856.1
- ProteinModelPortal:   Q9CMB4
- SMR:   Q9CMB4
- GeneID:   1244266
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0919
- NMPDR:   fig|272843.1.peg.919
- HOGENOM:   HBG747311
- OMA:   VLGTKQT
- ProtClustDB:   PRK10917
- BioCyc:   PMUL272843:PM0919-MONOMER
- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365
- SMART:   SM00487
- SMART:   SM00490
- TIGRFAMs:   TIGR00643

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =3.6.4.12

Molecular weight: Translated: 78027; Mature: 77895

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: PS51192 HELICASE_ATP_BIND_1; PS51194 HELICASE_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIQFLDAVPLTTLSGVGAAISDKLGRIGIHNLQDLLFHLPIRYEDRTRITPIHDLRPDA
CEEEEECCCCHHHHHCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCH
YATIEGLVQTCEVQFGKRPILNVSLSDGTSKIMLRFFNFNAGMKNSLQPGARVKAFGEVK
HHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHH
RGRFMAEIHHPEYQIIRDNAPLILEETLTPIYSTTEGIKQNSLRKLTDQALAVLENIQIA
CCCEEEEECCCCEEEEECCCCEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHE
EILPNEFNPHPFSLKEAIRFLHRPPPDVSLEALEKGTHPAQQRLIFEELLAHNLAMQKVR
ECCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
IGTQQFSAYPLSYQTDLKQRFLAQLPFTPTDAQVRVTQEIEQDLTHPFPMMRLVQGDVGS
CCHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHCCCCCHHHHHHCCCCCC
GKTLVAALAALLAIDNGKQVALMAPTEILAEQHATNFRRWFESLGIEVGWLAGKVKGKAR
CHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHH
QTELEKIRTGQVQMVVGTHALFQDEVEFSDLALVIVDEQHRFGVHQRLMLREKGKQADHY
HHHHHHHCCCCEEEEEECHHHHHCCCCCCCEEEEEECCCHHCCHHHHHHHHHCCCCCCCC
PHQLIMTATPIPRTLAMTVYADLDTSIIDELPPGRTPITTVAISEERRAEVIARVNHACV
CCEEEEECCCCCCEEEEEEEECCCHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHH
NEKRQAYWVCTLIDESEVLEAQAAEAIAEDLRKILPHLRIGLVHGRMKPAEKQDIMQAFK
CCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHEEHHHCCCCCCHHHHHHHHHH
QAEIDLLVATTVIEVGVDVPNASLMIIENAERLGLSQLHQLRGRVGRGTTASFCVLMYKP
HCCHHHHHHHHHHHHCCCCCCCEEEEEECHHHCCHHHHHHHHHCCCCCCCCEEEEEEECC
PLGKISQKRLQVLRDTQDGFVISEKDLEIRGPGEVLGTKQTGVAEFKVANLMRDRKMIPT
CCCHHHHHHHHHHHCCCCCEEEECCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCH
VQYYARRLIVEQPEVATKLIQRWINQREIYTHV
HHHHHHHHHCCCCHHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure 
TIQFLDAVPLTTLSGVGAAISDKLGRIGIHNLQDLLFHLPIRYEDRTRITPIHDLRPDA
EEEEECCCCHHHHHCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCH
YATIEGLVQTCEVQFGKRPILNVSLSDGTSKIMLRFFNFNAGMKNSLQPGARVKAFGEVK
HHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHH
RGRFMAEIHHPEYQIIRDNAPLILEETLTPIYSTTEGIKQNSLRKLTDQALAVLENIQIA
CCCEEEEECCCCEEEEECCCCEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHE
EILPNEFNPHPFSLKEAIRFLHRPPPDVSLEALEKGTHPAQQRLIFEELLAHNLAMQKVR
ECCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
IGTQQFSAYPLSYQTDLKQRFLAQLPFTPTDAQVRVTQEIEQDLTHPFPMMRLVQGDVGS
CCHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHCCCCCHHHHHHCCCCCC
GKTLVAALAALLAIDNGKQVALMAPTEILAEQHATNFRRWFESLGIEVGWLAGKVKGKAR
CHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHH
QTELEKIRTGQVQMVVGTHALFQDEVEFSDLALVIVDEQHRFGVHQRLMLREKGKQADHY
HHHHHHHCCCCEEEEEECHHHHHCCCCCCCEEEEEECCCHHCCHHHHHHHHHCCCCCCCC
PHQLIMTATPIPRTLAMTVYADLDTSIIDELPPGRTPITTVAISEERRAEVIARVNHACV
CCEEEEECCCCCCEEEEEEEECCCHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHH
NEKRQAYWVCTLIDESEVLEAQAAEAIAEDLRKILPHLRIGLVHGRMKPAEKQDIMQAFK
CCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHEEHHHCCCCCCHHHHHHHHHH
QAEIDLLVATTVIEVGVDVPNASLMIIENAERLGLSQLHQLRGRVGRGTTASFCVLMYKP
HCCHHHHHHHHHHHHCCCCCCCEEEEEECHHHCCHHHHHHHHHCCCCCCCCEEEEEEECC
PLGKISQKRLQVLRDTQDGFVISEKDLEIRGPGEVLGTKQTGVAEFKVANLMRDRKMIPT
CCCHHHHHHHHHHHCCCCCEEEECCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCH
VQYYARRLIVEQPEVATKLIQRWINQREIYTHV
HHHHHHHHHCCCCHHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100