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The map label for this gene is ubiC

Identifier: 15602783

GI number: 15602783

Start: 1083034

End: 1083546

Strand: Reverse

Name: ubiC

Synonym: PM0918

Alternate gene names: 15602783

Gene position: 1083546-1083034 (Counterclockwise)

Preceding gene: 15602784

Following gene: 15602782

Centisome position: 48.0

GC content: 39.18

Gene sequence:

>513_bases
ATGTCTAATTATTCCCAATTGTTACAAAATGCCACTTGGCAGCCTTCAACGGATATGCAATTACCTCTGTCGATTTCTTC
TTGGCTAGAGCTATCCACATCTTTAACTACACAGCTAAAACAAGCTTTTGGCGAAGTGAATGTATGTGTCTTAGCCGAGT
CATGGATAACGACGCTTAACGAGAATGAACGTCAATTTTTTCCAAAACAAGCATGTCCGTGTTGGTGTCGAGAAGTGATC
TTAAAAAGCCAAGATATACCATTAATTTTTGCGCGTACTTTAATTCCGGCTTCTTTATTGACGCAGCATAGTGAATTACA
ACAATTGGGCAATCGTGCGTTAGGTGAGTGGCTGTTTATGCAATCTGATCGTATAAGGCAAAAATTAGAATTAACGCATG
ATAAAAACACCGCACTTTATGCCCGCCGTGCCTTAATGAGTATTGGCGCTGAGAATATGATGGTTGCTGAATTATTTCTA
ACACCACAAATTTTTACGAGAGTAGTCAAATGA

Upstream 100 bases:

>100_bases
CCTACGGTGCAGTATTATGCGCGTCGTTTGATTGTTGAGCAACCAGAAGTGGCCACCAAATTAATCCAACGTTGGATTAA
TCAACGGGAGATTTATACGC

Downstream 100 bases:

>100_bases
ATAGCCCTTATCAACCTACTATCCTATTTTTTGATTCCGGTATGGGCGGCTTTAGTGTTTATAAAGAAACAAAGCAACTT
TTACCCGATTGTCACTATCT

Product: hypothetical protein

Products: NA

Alternate protein names: CL; CPL

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MSNYSQLLQNATWQPSTDMQLPLSISSWLELSTSLTTQLKQAFGEVNVCVLAESWITTLNENERQFFPKQACPCWCREVI
LKSQDIPLIFARTLIPASLLTQHSELQQLGNRALGEWLFMQSDRIRQKLELTHDKNTALYARRALMSIGAENMMVAELFL
TPQIFTRVVK

Sequences:

>Translated_170_residues
MSNYSQLLQNATWQPSTDMQLPLSISSWLELSTSLTTQLKQAFGEVNVCVLAESWITTLNENERQFFPKQACPCWCREVI
LKSQDIPLIFARTLIPASLLTQHSELQQLGNRALGEWLFMQSDRIRQKLELTHDKNTALYARRALMSIGAENMMVAELFL
TPQIFTRVVK
>Mature_169_residues
SNYSQLLQNATWQPSTDMQLPLSISSWLELSTSLTTQLKQAFGEVNVCVLAESWITTLNENERQFFPKQACPCWCREVIL
KSQDIPLIFARTLIPASLLTQHSELQQLGNRALGEWLFMQSDRIRQKLELTHDKNTALYARRALMSIGAENMMVAELFLT
PQIFTRVVK

Specific function: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway

COG id: COG3161

COG function: function code H; 4-hydroxybenzoate synthetase (chorismate lyase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiC family

Homologues:

Organism=Escherichia coli, GI87082361, Length=149, Percent_Identity=31.5436241610738, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIC_PASMU (Q9CMB5)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245855.1
- ProteinModelPortal:   Q9CMB5
- SMR:   Q9CMB5
- GeneID:   1244265
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0918
- NMPDR:   fig|272843.1.peg.918
- OMA:   KGYPLEI
- BioCyc:   PMUL272843:PM0918-MONOMER
- BRENDA:   4.1.3.40
- GO:   GO:0005737
- HAMAP:   MF_01632
- InterPro:   IPR007440

Pfam domain/function: PF04345 Chor_lyase

EC number: =4.1.3.40

Molecular weight: Translated: 19506; Mature: 19375

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: BINDING 77-77 BINDING 114-114

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNYSQLLQNATWQPSTDMQLPLSISSWLELSTSLTTQLKQAFGEVNVCVLAESWITTLN
CCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHC
ENERQFFPKQACPCWCREVILKSQDIPLIFARTLIPASLLTQHSELQQLGNRALGEWLFM
CCHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSDRIRQKLELTHDKNTALYARRALMSIGAENMMVAELFLTPQIFTRVVK
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHCC
>Mature Secondary Structure 
SNYSQLLQNATWQPSTDMQLPLSISSWLELSTSLTTQLKQAFGEVNVCVLAESWITTLN
CCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHC
ENERQFFPKQACPCWCREVILKSQDIPLIFARTLIPASLLTQHSELQQLGNRALGEWLFM
CCHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSDRIRQKLELTHDKNTALYARRALMSIGAENMMVAELFLTPQIFTRVVK
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100