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The map label for this gene is hexD [H]

Identifier: 15602643

GI number: 15602643

Start: 922102

End: 923283

Strand: Direct

Name: hexD [H]

Synonym: PM0778

Alternate gene names: 15602643

Gene position: 922102-923283 (Clockwise)

Preceding gene: 15602642

Following gene: 15602644

Centisome position: 40.85

GC content: 37.39

Gene sequence:

>1182_bases
ATGAAACCAATAAAAACATTATCTATTTCTTTTATCACAACGCTCATCCTCGCTGGCTGTCATAGCATGCCAACTTCGGG
ACCCGCTCAAAATCATATTATTGGGTTAAAAAAACCACAAAATGAGAGCTTGCCAAGTGTTGATGTGATTGAAATGAATG
ATAAAGTAGCACACACTTTGTTTAAACAAAAGCAATCGCAATCCTTTACTCAATTCAAACAGCAAAATAGCAACTATGCA
GATATCATTAATGTTGGCGATACATTAGATGTGTTGATTTGGGAAGCCGCACCCGCTATTTTATTCGGCAGTGTTCTGTC
ACAAACTGGTAGTGGCGGTGCAAATCTCACGACATTACCCGAACAAATTGTTGCACGCAATGGAAAAATCACAATCCCAT
TTTTAGGCCCTATCTTAGTAAAAGGCAAAACACCAGAGCAAATTCAAAGAGATATTGCTCATGCTTTATCCTCCTTAGCA
AATAAACCTCAGGTGATTGTTCGTTTAAATAAAAATAATTCAAAAAATGTCACCATTCTCCGCCAAGGCAATAGTGTCAG
AATGCCATTAACATCACAAGGGGAACGTGTACTTGATGCTATTGCCGCAGTGGGCGGTGCCACAGAAAATCTACAAGATA
TTTCTGTTCAACTTACACGTGGTAAAGAAGTAAAAATGCTTTCCTTAGAAAAATTAGCCACTCATCCTGAAGAAAACATT
CTGCTACGTTCAAATGATGTCGTTACATTACTGAATAAACCTCTTAGTTTCACAGGATTAGGTGCACTCGGGACGAATAA
ACAGGTGAAATTCTCTGCGAATGGCTTAACACTCGCAGAAGGCATCGGAGAAATGGGTGGGCTATTAGATAACCGTGCTG
ATCCTAAAGGGGTTTTTGTCTTCCGTTATATTCCATTTAATAAATTATCTCTCGCAGAACAAACTAAATGGAAAGCTCGT
GGCTATGATAACGACATGGAGATTCCAACAGTTTATAGTGTCAATCTACTTAATCCAAACGCGTTGTTTTGGTTACAACG
TTTCCCTATTCAAGATAAAGATTTAGTTTATGTATCAAATGCACCAATGGCAGAATTCCAAAAATTCTTAAAATTAGTGT
TTTCTATCACCTCTCCTGTTACGGGTACACTTCATAATATTAATGTAATTAAAAATTTATAA

Upstream 100 bases:

>100_bases
ATCTTCCTCTCCTAAACGAGAATTTTTTCAATATGACCAACATCCGATCATGGATGTTATTTCTTATGCAATCATTAATT
AAATCTTAAGAGAGATTATT

Downstream 100 bases:

>100_bases
GGATAGAGAATGATCGAAACAAAAATGCAAAAAAATCAATTTAAAAAATGGTCCCGAAAATTTCGAAAAATAAGTACACT
CTTTAAATACATGGTAATAC

Product: HexD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MKPIKTLSISFITTLILAGCHSMPTSGPAQNHIIGLKKPQNESLPSVDVIEMNDKVAHTLFKQKQSQSFTQFKQQNSNYA
DIINVGDTLDVLIWEAAPAILFGSVLSQTGSGGANLTTLPEQIVARNGKITIPFLGPILVKGKTPEQIQRDIAHALSSLA
NKPQVIVRLNKNNSKNVTILRQGNSVRMPLTSQGERVLDAIAAVGGATENLQDISVQLTRGKEVKMLSLEKLATHPEENI
LLRSNDVVTLLNKPLSFTGLGALGTNKQVKFSANGLTLAEGIGEMGGLLDNRADPKGVFVFRYIPFNKLSLAEQTKWKAR
GYDNDMEIPTVYSVNLLNPNALFWLQRFPIQDKDLVYVSNAPMAEFQKFLKLVFSITSPVTGTLHNINVIKNL

Sequences:

>Translated_393_residues
MKPIKTLSISFITTLILAGCHSMPTSGPAQNHIIGLKKPQNESLPSVDVIEMNDKVAHTLFKQKQSQSFTQFKQQNSNYA
DIINVGDTLDVLIWEAAPAILFGSVLSQTGSGGANLTTLPEQIVARNGKITIPFLGPILVKGKTPEQIQRDIAHALSSLA
NKPQVIVRLNKNNSKNVTILRQGNSVRMPLTSQGERVLDAIAAVGGATENLQDISVQLTRGKEVKMLSLEKLATHPEENI
LLRSNDVVTLLNKPLSFTGLGALGTNKQVKFSANGLTLAEGIGEMGGLLDNRADPKGVFVFRYIPFNKLSLAEQTKWKAR
GYDNDMEIPTVYSVNLLNPNALFWLQRFPIQDKDLVYVSNAPMAEFQKFLKLVFSITSPVTGTLHNINVIKNL
>Mature_393_residues
MKPIKTLSISFITTLILAGCHSMPTSGPAQNHIIGLKKPQNESLPSVDVIEMNDKVAHTLFKQKQSQSFTQFKQQNSNYA
DIINVGDTLDVLIWEAAPAILFGSVLSQTGSGGANLTTLPEQIVARNGKITIPFLGPILVKGKTPEQIQRDIAHALSSLA
NKPQVIVRLNKNNSKNVTILRQGNSVRMPLTSQGERVLDAIAAVGGATENLQDISVQLTRGKEVKMLSLEKLATHPEENI
LLRSNDVVTLLNKPLSFTGLGALGTNKQVKFSANGLTLAEGIGEMGGLLDNRADPKGVFVFRYIPFNKLSLAEQTKWKAR
GYDNDMEIPTVYSVNLLNPNALFWLQRFPIQDKDLVYVSNAPMAEFQKFLKLVFSITSPVTGTLHNINVIKNL

Specific function: May form an ATP-driven capsule polysaccharide export apparatus, in association with the BexA, BexB and BexC proteins. May function as a membrane anchor for capsular polysaccharides. Possible porin properties [H]

COG id: COG1596

COG function: function code M; Periplasmic protein involved in polysaccharide export

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BexD/CtrA/VexA family [H]

Homologues:

Organism=Escherichia coli, GI1787218, Length=411, Percent_Identity=26.7639902676399, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788376, Length=312, Percent_Identity=26.2820512820513, Blast_Score=89, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003715 [H]

Pfam domain/function: PF02563 Poly_export [H]

EC number: NA

Molecular weight: Translated: 43004; Mature: 43004

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPIKTLSISFITTLILAGCHSMPTSGPAQNHIIGLKKPQNESLPSVDVIEMNDKVAHTL
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCCEEEEECCHHHHHHH
FKQKQSQSFTQFKQQNSNYADIINVGDTLDVLIWEAAPAILFGSVLSQTGSGGANLTTLP
HHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCH
EQIVARNGKITIPFLGPILVKGKTPEQIQRDIAHALSSLANKPQVIVRLNKNNSKNVTIL
HHHHHCCCCEEEEEECEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEE
RQGNSVRMPLTSQGERVLDAIAAVGGATENLQDISVQLTRGKEVKMLSLEKLATHPEENI
ECCCEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEEEHHHHHCCCCCCE
LLRSNDVVTLLNKPLSFTGLGALGTNKQVKFSANGLTLAEGIGEMGGLLDNRADPKGVFV
EEECCCEEEEECCCCCEEECCCCCCCCEEEEECCCEEHHHHHHHHHHHHCCCCCCCEEEE
FRYIPFNKLSLAEQTKWKARGYDNDMEIPTVYSVNLLNPNALFWLQRFPIQDKDLVYVSN
EEECCCCCCCHHHHCCHHHCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCEEEECC
APMAEFQKFLKLVFSITSPVTGTLHNINVIKNL
CCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCC
>Mature Secondary Structure
MKPIKTLSISFITTLILAGCHSMPTSGPAQNHIIGLKKPQNESLPSVDVIEMNDKVAHTL
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCCEEEEECCHHHHHHH
FKQKQSQSFTQFKQQNSNYADIINVGDTLDVLIWEAAPAILFGSVLSQTGSGGANLTTLP
HHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCH
EQIVARNGKITIPFLGPILVKGKTPEQIQRDIAHALSSLANKPQVIVRLNKNNSKNVTIL
HHHHHCCCCEEEEEECEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEE
RQGNSVRMPLTSQGERVLDAIAAVGGATENLQDISVQLTRGKEVKMLSLEKLATHPEENI
ECCCEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEEEHHHHHCCCCCCE
LLRSNDVVTLLNKPLSFTGLGALGTNKQVKFSANGLTLAEGIGEMGGLLDNRADPKGVFV
EEECCCEEEEECCCCCEEECCCCCCCCEEEEECCCEEHHHHHHHHHHHHCCCCCCCEEEE
FRYIPFNKLSLAEQTKWKARGYDNDMEIPTVYSVNLLNPNALFWLQRFPIQDKDLVYVSN
EEECCCCCCCHHHHCCHHHCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCEEEECC
APMAEFQKFLKLVFSITSPVTGTLHNINVIKNL
CCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2082145 [H]