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The map label for this gene is ugd [H]

Identifier: 15602641

GI number: 15602641

Start: 919485

End: 920657

Strand: Direct

Name: ugd [H]

Synonym: PM0776

Alternate gene names: 15602641

Gene position: 919485-920657 (Clockwise)

Preceding gene: 15602640

Following gene: 15602642

Centisome position: 40.73

GC content: 34.7

Gene sequence:

>1173_bases
ATGAAGAAAATTACAATTGCTGGGGCTGGCTATGTTGGTTTATCCAATGCAGTATTATTAGCTCAACACCACAATGTGAT
CTTATTAGATATTGATCAAAATAAAGTTGATTTAATTAATAATAAAAAATCGCCCATCACAGATAAAGAAATCGAAGATT
TCTTACAAAATAAATCACTGACAATGATGGCAACAACAGATAAAGAAGTGGCATTAAAAAACGCAGACTTTGTCATCATC
GCAACGCCAACAGACTATAATACCGAAACAGGTTATTTTAATACATCCACTGTTGAAGCTGTCATTGAACAAACCCTTTC
AATCAATCCACAAGCAACGATTATTATAAAATCAACAATTCCCGTTGGTTTTACCGAAAACATGCGTGAAAAATTTAATA
CCCCAAATCTTATCTTTTCACCTGAATTTCTAAGAGAGGGAAAAGCCCTTTACGATAATTTGTATCCAAGCAGAATTATT
GTTGGCAGTACTTCTTATCAAGCAAAAGTATTTGCCGATATGTTGACACAGTGTGCCAGAAAAAAAGATGTAACTGTTTT
ATTTACACACAATACTGAGGCCGAAGCTGTTAAATTATTTGCAAATACGTATCTCGCAATGCGAGTTGCCTTTTTTAATG
AATTAGATACTTATGCGAGTCTTCACCATTTAAATACAAAAGACATTATCAATGGTATTTCTACTGATCCTCGCATTGGT
ACACACTACAATAACCCAAGTTTCGGCTATGGCGGTTATTGTTTACCCAAAGACACTAAACAGTTACTGGCTAACTATGC
TGACGTGCCTCAAAATCTCATTGAAGCCATTGTCAAATCTAATGAAACCAGAAAACGTTTCATTACTCATGATGTATTAA
ATAAGAAACCTAAAACTGTTGGTATTTATCGTTTAATCATGAAGTCAGGTTCTGATAACTTCAGAGCTTCTGCTATTCTC
GATATTATGCCGCATCTCAAAGAAAACGGTGTTGAGATTGTGATTTATGAGCCAACCTTAAATCAACAGGCATTTGAGGA
CTACCCCGTTATTAATCAACTCTCTGAATTTATTAATCGCTCTGATGTCATTCTCGCTAATCGTTCTGAGCCAGATTTAA
ATCAATGTTCCCATAAAATCTATACAAGAGATATTTTTGGCGGTGATGCTTAA

Upstream 100 bases:

>100_bases
TGTTAACAAGTTCATTATTAATAGTATAACTCTATAAAACACTTGCATTTTATTAAAAATAAAATCCTATAATATTTGCA
GTTTAAATAAAGGATAAAAA

Downstream 100 bases:

>100_bases
CCTGTTTAAAATCATAAAAAAGTATGTGCATATTCAATCTTTATTACACAAAAAAGAATATGCCTTACTTTATGCTAAAT
ACATAAACCAGCTTTCTATC

Product: hypothetical protein

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MKKITIAGAGYVGLSNAVLLAQHHNVILLDIDQNKVDLINNKKSPITDKEIEDFLQNKSLTMMATTDKEVALKNADFVII
ATPTDYNTETGYFNTSTVEAVIEQTLSINPQATIIIKSTIPVGFTENMREKFNTPNLIFSPEFLREGKALYDNLYPSRII
VGSTSYQAKVFADMLTQCARKKDVTVLFTHNTEAEAVKLFANTYLAMRVAFFNELDTYASLHHLNTKDIINGISTDPRIG
THYNNPSFGYGGYCLPKDTKQLLANYADVPQNLIEAIVKSNETRKRFITHDVLNKKPKTVGIYRLIMKSGSDNFRASAIL
DIMPHLKENGVEIVIYEPTLNQQAFEDYPVINQLSEFINRSDVILANRSEPDLNQCSHKIYTRDIFGGDA

Sequences:

>Translated_390_residues
MKKITIAGAGYVGLSNAVLLAQHHNVILLDIDQNKVDLINNKKSPITDKEIEDFLQNKSLTMMATTDKEVALKNADFVII
ATPTDYNTETGYFNTSTVEAVIEQTLSINPQATIIIKSTIPVGFTENMREKFNTPNLIFSPEFLREGKALYDNLYPSRII
VGSTSYQAKVFADMLTQCARKKDVTVLFTHNTEAEAVKLFANTYLAMRVAFFNELDTYASLHHLNTKDIINGISTDPRIG
THYNNPSFGYGGYCLPKDTKQLLANYADVPQNLIEAIVKSNETRKRFITHDVLNKKPKTVGIYRLIMKSGSDNFRASAIL
DIMPHLKENGVEIVIYEPTLNQQAFEDYPVINQLSEFINRSDVILANRSEPDLNQCSHKIYTRDIFGGDA
>Mature_390_residues
MKKITIAGAGYVGLSNAVLLAQHHNVILLDIDQNKVDLINNKKSPITDKEIEDFLQNKSLTMMATTDKEVALKNADFVII
ATPTDYNTETGYFNTSTVEAVIEQTLSINPQATIIIKSTIPVGFTENMREKFNTPNLIFSPEFLREGKALYDNLYPSRII
VGSTSYQAKVFADMLTQCARKKDVTVLFTHNTEAEAVKLFANTYLAMRVAFFNELDTYASLHHLNTKDIINGISTDPRIG
THYNNPSFGYGGYCLPKDTKQLLANYADVPQNLIEAIVKSNETRKRFITHDVLNKKPKTVGIYRLIMKSGSDNFRASAIL
DIMPHLKENGVEIVIYEPTLNQQAFEDYPVINQLSEFINRSDVILANRSEPDLNQCSHKIYTRDIFGGDA

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=375, Percent_Identity=26.6666666666667, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI296040438, Length=250, Percent_Identity=28, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI296040443, Length=241, Percent_Identity=26.1410788381743, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI1788340, Length=387, Percent_Identity=59.4315245478036, Blast_Score=487, Evalue=1e-139,
Organism=Escherichia coli, GI48994968, Length=403, Percent_Identity=24.8138957816377, Blast_Score=89, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17560350, Length=396, Percent_Identity=25.7575757575758, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17136908, Length=391, Percent_Identity=24.0409207161125, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 43819; Mature: 43819

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKITIAGAGYVGLSNAVLLAQHHNVILLDIDQNKVDLINNKKSPITDKEIEDFLQNKSL
CCEEEEECCCCCCCCCEEEEEECCCEEEEEECCCCEEEECCCCCCCCHHHHHHHHCCCCE
TMMATTDKEVALKNADFVIIATPTDYNTETGYFNTSTVEAVIEQTLSINPQATIIIKSTI
EEEEECCCHHEEECCCEEEEECCCCCCCCCCEECHHHHHHHHHHHHCCCCCEEEEEEECC
PVGFTENMREKFNTPNLIFSPEFLREGKALYDNLYPSRIIVGSTSYQAKVFADMLTQCAR
CCCCCHHHHHHCCCCCEEECHHHHHCCHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHC
KKDVTVLFTHNTEAEAVKLFANTYLAMRVAFFNELDTYASLHHLNTKDIINGISTDPRIG
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCC
THYNNPSFGYGGYCLPKDTKQLLANYADVPQNLIEAIVKSNETRKRFITHDVLNKKPKTV
CCCCCCCCCCCCEECCHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHH
GIYRLIMKSGSDNFRASAILDIMPHLKENGVEIVIYEPTLNQQAFEDYPVINQLSEFINR
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHCCCHHHHHHHHHCC
SDVILANRSEPDLNQCSHKIYTRDIFGGDA
CCEEEEECCCCCHHHHHHHHEEEECCCCCC
>Mature Secondary Structure
MKKITIAGAGYVGLSNAVLLAQHHNVILLDIDQNKVDLINNKKSPITDKEIEDFLQNKSL
CCEEEEECCCCCCCCCEEEEEECCCEEEEEECCCCEEEECCCCCCCCHHHHHHHHCCCCE
TMMATTDKEVALKNADFVIIATPTDYNTETGYFNTSTVEAVIEQTLSINPQATIIIKSTI
EEEEECCCHHEEECCCEEEEECCCCCCCCCCEECHHHHHHHHHHHHCCCCCEEEEEEECC
PVGFTENMREKFNTPNLIFSPEFLREGKALYDNLYPSRIIVGSTSYQAKVFADMLTQCAR
CCCCCHHHHHHCCCCCEEECHHHHHCCHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHC
KKDVTVLFTHNTEAEAVKLFANTYLAMRVAFFNELDTYASLHHLNTKDIINGISTDPRIG
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCC
THYNNPSFGYGGYCLPKDTKQLLANYADVPQNLIEAIVKSNETRKRFITHDVLNKKPKTV
CCCCCCCCCCCCEECCHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHH
GIYRLIMKSGSDNFRASAILDIMPHLKENGVEIVIYEPTLNQQAFEDYPVINQLSEFINR
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHCCCHHHHHHHHHCC
SDVILANRSEPDLNQCSHKIYTRDIFGGDA
CCEEEEECCCCCHHHHHHHHEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9383197 [H]