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The map label for this gene is thiL [H]

Identifier: 15602594

GI number: 15602594

Start: 858488

End: 859480

Strand: Reverse

Name: thiL [H]

Synonym: PM0729

Alternate gene names: 15602594

Gene position: 859480-858488 (Counterclockwise)

Preceding gene: 15602595

Following gene: 15602593

Centisome position: 38.07

GC content: 41.29

Gene sequence:

>993_bases
ATGAGTCATGGCGAATTTGACATAATTCAACGTTATTTCACCGCGTCAAAACGCACCGCGCGTAAAGATGTGATTTTGTC
TATTGGGGACGATTGTGCCATTACAGAATTACGTCAAAATCAACGTTTAGTCATTACAACCGATACTATGGTAGAAAATA
CACATTTTCTACCGAGTATGCATGCAGCAGATTTAGCTTATAAAGCCGCTGTCACGAATTTAAGTGATCTTGCTGCCATG
GGCGCTGAGCCGGCTTGGGTTTCGTTGGCGTTAACTTTACCCGATGTCGATGCTCAGTGGTTAAGTGATTTTAGTCAAAG
TTTTTTTGATGTGTTAGATCACTATAATGTGGATTTAATCGGTGGAGATACCACGAAAGGTCCCTTGTCTGTGACGATAA
CCGCACATGGCATTATTCCGAAAGGAAAAGGTTTATGTCGTCATAGTGCGAGCGTGGGGGATTGGATCTATGTTTCCGGT
ACCTTAGGTGACAGTGCAGCAGGTTTATCGTTATTGTTAAGTCAGCAGACACCACTTAACTCCGATCATGAATTTCTTAT
CCAACGTCATCTTCGTCCTACACCGCGTGTTTTACTCGGTTTAGAATTAGCTGTCTCTTCTTTAGCCAATGCGGCAATTG
ATATCTCAGATGGTTTTTTGGCCGATTTAGATCATATTCTTACACGTAGCCAATGTGGTGCGGTGATTGAGTTGGATAAA
TTACCGCTTTCTTCTTCTTTAGTGAATGTTTTTGGTGTTGAACAAGCAGAGACCTTTGCGTTAAGTGGTGGTGAGGATTA
TGAGCTTTGTTTTACGGTACCCGACAGTAATAAAGCGAAATTAGAGCGTGCGTTAGCTTATATTGGCGTGGATTATACTT
GTGTTGGACAAGTTCGCGCGATTAGTCCACAAAATAAAAAACGCATCAAATTTCAACGCGATGGAAATCCGATTGATATC
ACTATTCAATCGGGTTTTGATCATTTCAAATAA

Upstream 100 bases:

>100_bases
GCAAAAGTATTTGGTGCAGAAGACAGTCATAAATATGTCAATGGCGTATTAGATAAAGTCGCACCGGTGTTATCACGCAA
ATAAGTAGCATAGGTGAAGA

Downstream 100 bases:

>100_bases
GATGAGCTTATGCTAAAAACCCCGCTTCAACAGCTTAAATTAAGCAATCCCATTCATTTTCTCGCCCTCGGCTTTGGCGC
CGGGTTGATTCGTCCTGCAC

Product: hypothetical protein

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MSHGEFDIIQRYFTASKRTARKDVILSIGDDCAITELRQNQRLVITTDTMVENTHFLPSMHAADLAYKAAVTNLSDLAAM
GAEPAWVSLALTLPDVDAQWLSDFSQSFFDVLDHYNVDLIGGDTTKGPLSVTITAHGIIPKGKGLCRHSASVGDWIYVSG
TLGDSAAGLSLLLSQQTPLNSDHEFLIQRHLRPTPRVLLGLELAVSSLANAAIDISDGFLADLDHILTRSQCGAVIELDK
LPLSSSLVNVFGVEQAETFALSGGEDYELCFTVPDSNKAKLERALAYIGVDYTCVGQVRAISPQNKKRIKFQRDGNPIDI
TIQSGFDHFK

Sequences:

>Translated_330_residues
MSHGEFDIIQRYFTASKRTARKDVILSIGDDCAITELRQNQRLVITTDTMVENTHFLPSMHAADLAYKAAVTNLSDLAAM
GAEPAWVSLALTLPDVDAQWLSDFSQSFFDVLDHYNVDLIGGDTTKGPLSVTITAHGIIPKGKGLCRHSASVGDWIYVSG
TLGDSAAGLSLLLSQQTPLNSDHEFLIQRHLRPTPRVLLGLELAVSSLANAAIDISDGFLADLDHILTRSQCGAVIELDK
LPLSSSLVNVFGVEQAETFALSGGEDYELCFTVPDSNKAKLERALAYIGVDYTCVGQVRAISPQNKKRIKFQRDGNPIDI
TIQSGFDHFK
>Mature_329_residues
SHGEFDIIQRYFTASKRTARKDVILSIGDDCAITELRQNQRLVITTDTMVENTHFLPSMHAADLAYKAAVTNLSDLAAMG
AEPAWVSLALTLPDVDAQWLSDFSQSFFDVLDHYNVDLIGGDTTKGPLSVTITAHGIIPKGKGLCRHSASVGDWIYVSGT
LGDSAAGLSLLLSQQTPLNSDHEFLIQRHLRPTPRVLLGLELAVSSLANAAIDISDGFLADLDHILTRSQCGAVIELDKL
PLSSSLVNVFGVEQAETFALSGGEDYELCFTVPDSNKAKLERALAYIGVDYTCVGQVRAISPQNKKRIKFQRDGNPIDIT
IQSGFDHFK

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=330, Percent_Identity=53.9393939393939, Blast_Score=349, Evalue=1e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 35907; Mature: 35776

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00079 MULTICOPPER_OXIDASE1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHGEFDIIQRYFTASKRTARKDVILSIGDDCAITELRQNQRLVITTDTMVENTHFLPSM
CCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHCCCEEEEEECCEECCCCCCCCC
HAADLAYKAAVTNLSDLAAMGAEPAWVSLALTLPDVDAQWLSDFSQSFFDVLDHYNVDLI
HHHHHHHHHHHCCHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEE
GGDTTKGPLSVTITAHGIIPKGKGLCRHSASVGDWIYVSGTLGDSAAGLSLLLSQQTPLN
CCCCCCCCEEEEEEEEECCCCCCCCEECCCCCCCEEEEEECCCCCCCCCEEEEECCCCCC
SDHEFLIQRHLRPTPRVLLGLELAVSSLANAAIDISDGFLADLDHILTRSQCGAVIELDK
CCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCEEECCCCHHHHHHHHHHHHHCCCEEEEEC
LPLSSSLVNVFGVEQAETFALSGGEDYELCFTVPDSNKAKLERALAYIGVDYTCVGQVRA
CCCCHHHHHHHCCCCCCEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEECEEEE
ISPQNKKRIKFQRDGNPIDITIQSGFDHFK
CCCCCCCEEEEEECCCEEEEEEECCCCCCC
>Mature Secondary Structure 
SHGEFDIIQRYFTASKRTARKDVILSIGDDCAITELRQNQRLVITTDTMVENTHFLPSM
CCCHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHCCCEEEEEECCEECCCCCCCCC
HAADLAYKAAVTNLSDLAAMGAEPAWVSLALTLPDVDAQWLSDFSQSFFDVLDHYNVDLI
HHHHHHHHHHHCCHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEE
GGDTTKGPLSVTITAHGIIPKGKGLCRHSASVGDWIYVSGTLGDSAAGLSLLLSQQTPLN
CCCCCCCCEEEEEEEEECCCCCCCCEECCCCCCCEEEEEECCCCCCCCCEEEEECCCCCC
SDHEFLIQRHLRPTPRVLLGLELAVSSLANAAIDISDGFLADLDHILTRSQCGAVIELDK
CCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCEEECCCCHHHHHHHHHHHHHCCCEEEEEC
LPLSSSLVNVFGVEQAETFALSGGEDYELCFTVPDSNKAKLERALAYIGVDYTCVGQVRA
CCCCHHHHHHHCCCCCCEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEECEEEE
ISPQNKKRIKFQRDGNPIDITIQSGFDHFK
CCCCCCCEEEEEECCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]