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The map label for this gene is aroF [H]

Identifier: 15602530

GI number: 15602530

Start: 774500

End: 775552

Strand: Reverse

Name: aroF [H]

Synonym: PM0665

Alternate gene names: 15602530

Gene position: 775552-774500 (Counterclockwise)

Preceding gene: 15602535

Following gene: 15602529

Centisome position: 34.35

GC content: 40.46

Gene sequence:

>1053_bases
GTGAATAAAGATAACATACATAATGTCAATATTGTTGGTGAAAAGGTACTGATTACCCCAAAAGAATTGAAGGAAAAACT
CCCTCTATCCCTTCCTCTTCGTAGCCAAATAGCGCAATCACGCCGTGATATTGCGAATATCATCCATAAAAAAGATCAGC
GTTTATTGGTTGTGATTGGACCATGTTCTATTCATGATCCGATCGCGGCTTTAGAATACGCTTCACGTTTAAAACACTTA
GCAGAAGAATTACAAGATCAATTGTATATTGTGATGCGAGTGTATTTTGAAAAACCAAGAACAACTGTTGGCTGGAAAGG
ATTGATTAATGATCCGAAATTGGATGGTTCATTTGATGTGGAACATGGCTTACATATTGCACGAGCATTACTGCTAGAGC
TGGCTGAAATGGGACTCCCTTTGGCAACCGAAGCACTTGATCCCATTATGCCGCAATATATTGCTGATCTATTTAGTTGG
TCTGCGATTGGTGCGAGAACGACAGAATCACAAACGCACAGAGAAATGTCATCAGGTTTATCCATGGCAGTGGGATTTAA
AAATGGTACGGATGGCAGTTTAGCCACCGCAATTAATGCAATGAAAGCAGCGTCAGTTGGACACAGTTTTATTGGGATTA
ATCAACAAGGTCAAGTCAATCTATTACATACAGCGGGCAACCCTAATGGGCATGTGATTTTGCGTGGCGGAAAATCACCA
AATTATGAAGCTGAACATATCGCACTTTGTGAACAAGAATTGCAAAAAGCAGGTTTGACGCAAGCAATTATGATCGATTG
TAGCCATGGTAACTCGAATAAAGATTACCGTTTGCAGCCGAAAGTGGCAAAAAATGCCGTACAGCAAATTGTGAAGGGAA
ATCGCTCTATTATCGGGTTGATGTTAGAAAGTCATTTATACGCAGGTAATCAAAGTGCTGATCAGCCATTGAGTGAAATG
CAATATGGGGTTTCGATTACGGATGCCTGTATTGATTGGCAGACGACAGAACAATTATTACGTGAAATGACGAGCGCATT
GCGCCAAAAATAA

Upstream 100 bases:

>100_bases
CTCTTGAAAATTTAATGTAAATTATTTATTACATTTAGTGTATATAAATGTTTACATGATTTAATGTGTTCAAAAATAAT
GATGTACTAAGGAATAAAAA

Downstream 100 bases:

>100_bases
GGATGCAACGTGGATACGTTAAATAAGTTAAGAACACAGATTGATCAAGTTGATCGTCAGTTATTACAGCTTTTAGCACA
GCGACTTGAGTTAGTGAAAC

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MNKDNIHNVNIVGEKVLITPKELKEKLPLSLPLRSQIAQSRRDIANIIHKKDQRLLVVIGPCSIHDPIAALEYASRLKHL
AEELQDQLYIVMRVYFEKPRTTVGWKGLINDPKLDGSFDVEHGLHIARALLLELAEMGLPLATEALDPIMPQYIADLFSW
SAIGARTTESQTHREMSSGLSMAVGFKNGTDGSLATAINAMKAASVGHSFIGINQQGQVNLLHTAGNPNGHVILRGGKSP
NYEAEHIALCEQELQKAGLTQAIMIDCSHGNSNKDYRLQPKVAKNAVQQIVKGNRSIIGLMLESHLYAGNQSADQPLSEM
QYGVSITDACIDWQTTEQLLREMTSALRQK

Sequences:

>Translated_350_residues
MNKDNIHNVNIVGEKVLITPKELKEKLPLSLPLRSQIAQSRRDIANIIHKKDQRLLVVIGPCSIHDPIAALEYASRLKHL
AEELQDQLYIVMRVYFEKPRTTVGWKGLINDPKLDGSFDVEHGLHIARALLLELAEMGLPLATEALDPIMPQYIADLFSW
SAIGARTTESQTHREMSSGLSMAVGFKNGTDGSLATAINAMKAASVGHSFIGINQQGQVNLLHTAGNPNGHVILRGGKSP
NYEAEHIALCEQELQKAGLTQAIMIDCSHGNSNKDYRLQPKVAKNAVQQIVKGNRSIIGLMLESHLYAGNQSADQPLSEM
QYGVSITDACIDWQTTEQLLREMTSALRQK
>Mature_350_residues
MNKDNIHNVNIVGEKVLITPKELKEKLPLSLPLRSQIAQSRRDIANIIHKKDQRLLVVIGPCSIHDPIAALEYASRLKHL
AEELQDQLYIVMRVYFEKPRTTVGWKGLINDPKLDGSFDVEHGLHIARALLLELAEMGLPLATEALDPIMPQYIADLFSW
SAIGARTTESQTHREMSSGLSMAVGFKNGTDGSLATAINAMKAASVGHSFIGINQQGQVNLLHTAGNPNGHVILRGGKSP
NYEAEHIALCEQELQKAGLTQAIMIDCSHGNSNKDYRLQPKVAKNAVQQIVKGNRSIIGLMLESHLYAGNQSADQPLSEM
QYGVSITDACIDWQTTEQLLREMTSALRQK

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=343, Percent_Identity=70.2623906705539, Blast_Score=514, Evalue=1e-147,
Organism=Escherichia coli, GI1786969, Length=338, Percent_Identity=55.3254437869823, Blast_Score=384, Evalue=1e-108,
Organism=Escherichia coli, GI1787996, Length=333, Percent_Identity=51.3513513513513, Blast_Score=354, Evalue=5e-99,
Organism=Saccharomyces cerevisiae, GI6319726, Length=352, Percent_Identity=49.4318181818182, Blast_Score=345, Evalue=4e-96,
Organism=Saccharomyces cerevisiae, GI6320240, Length=356, Percent_Identity=46.6292134831461, Blast_Score=341, Evalue=1e-94,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38565; Mature: 38565

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKDNIHNVNIVGEKVLITPKELKEKLPLSLPLRSQIAQSRRDIANIIHKKDQRLLVVIG
CCCCCCEEEEEECCEEEECHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEC
PCSIHDPIAALEYASRLKHLAEELQDQLYIVMRVYFEKPRTTVGWKGLINDPKLDGSFDV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCH
EHGLHIARALLLELAEMGLPLATEALDPIMPQYIADLFSWSAIGARTTESQTHREMSSGL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
SMAVGFKNGTDGSLATAINAMKAASVGHSFIGINQQGQVNLLHTAGNPNGHVILRGGKSP
EEEEECCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCEEEEEECCCCCCEEEEECCCCC
NYEAEHIALCEQELQKAGLTQAIMIDCSHGNSNKDYRLQPKVAKNAVQQIVKGNRSIIGL
CCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEECCHHHHHHHHHHHCCCCCEEHH
MLESHLYAGNQSADQPLSEMQYGVSITDACIDWQTTEQLLREMTSALRQK
HHHHHHCCCCCCCCCCHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKDNIHNVNIVGEKVLITPKELKEKLPLSLPLRSQIAQSRRDIANIIHKKDQRLLVVIG
CCCCCCEEEEEECCEEEECHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEC
PCSIHDPIAALEYASRLKHLAEELQDQLYIVMRVYFEKPRTTVGWKGLINDPKLDGSFDV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCH
EHGLHIARALLLELAEMGLPLATEALDPIMPQYIADLFSWSAIGARTTESQTHREMSSGL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
SMAVGFKNGTDGSLATAINAMKAASVGHSFIGINQQGQVNLLHTAGNPNGHVILRGGKSP
EEEEECCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCEEEEEECCCCCCEEEEECCCCC
NYEAEHIALCEQELQKAGLTQAIMIDCSHGNSNKDYRLQPKVAKNAVQQIVKGNRSIIGL
CCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEECCHHHHHHHHHHHCCCCCEEHH
MLESHLYAGNQSADQPLSEMQYGVSITDACIDWQTTEQLLREMTSALRQK
HHHHHHCCCCCCCCCCHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]