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The map label for this gene is mlc [H]

Identifier: 15602507

GI number: 15602507

Start: 742976

End: 744187

Strand: Reverse

Name: mlc [H]

Synonym: PM0642

Alternate gene names: 15602507

Gene position: 744187-742976 (Counterclockwise)

Preceding gene: 15602510

Following gene: 15602506

Centisome position: 32.97

GC content: 36.39

Gene sequence:

>1212_bases
ATGCCAAAAATTAGAAAAGAGGATAAATTACCATTACGCTTGACACAGCTTGGTAAAATTTATCGTTTAGTTGAACAATT
TGAAGAAATTTCTCGTATAGACTTATCAAAACTTTCACGTTTAGCACCAGCGACCATTACGGCATTGACACGCGAATTAA
TCAAAGAAAAATTGATTGTCGAGCGTGCCGTTCAAAATACAGAAAGTCGTGGGCGTCCTGCCATTGGATTATGTGTTTCA
CCTTTTTATTGGCAATCTTTATGTGCAACCTTGGTTGAAAACCGTTTTGAACTGATTCTAAGTGAATTAGATGGCGGTGA
AATAAAAAGTAAAAGCTATCCTTTAACCACCTCCGATTTAGTGCACTTAGATCAGGTATTAGTCCAATATTTACAACAAT
TTCTTTTTGAAACCCAACATGAACTAAATCATTTAATTACTTTTTCCATTGCGGTTGGTGGCGAGCTTGATAGTAAAAAT
CGATTGATAAAGTTAGGCGATGTCAACCTTGATCTTGATTTAGAAAGCCTATTTAAACCGTATTTTAAAGTGCCTGTATT
AGTGACAGAATATTTCCAAACTTGGTTAATGGCAGAGTCAACATTAGGAAGTGTGATTAATTGCGATAATGTGTTATTCC
TACAGTTGGATGATGTGATTAATTTTAGTGTATTGTCTAAAGGCGAGCTCTTAACTCATCAGCATCAAGTCAGAAGTCAT
ATCAATAAAATGATTGTACCGAAGATAAGCCCTTTACAAGACCTGATTAGCCCACATTTAGCGGATCTTGAACGCTATCA
ACTCCAACATCAAGTTACCCATAAAGCCATTTACCCTTTAATTACGCATTATTTCCCAGAAGCGGCCTTAGCACAAAGTG
AAATTGAATTTTTATGTCAGAAAGCGAATGCGCAGAATCCACAAGCTCAACAAATTCTGCATTATGTTGCAGATAGTCTG
GCATATATTTTAATGAATCTTGTCAATATTTTTGATTCTGAGAAAATCATGTTAAGTTCGAGCTTTTTAAGTGCAAAAGA
AGTTTTTCTTCCTCGTGTGAATCAAACGCTCAAAGCAAATTTAGGCGCAGATTACCCTCATGTTGAAGTAATTACCGGAC
GCTATGAATGGAATACACCAGTAGTTGCAGCGGCGGCGATTAAACAAGGTATCTATGACGGTAGCTTGCTTGGGCATTTT
ATTAAGCACTAA

Upstream 100 bases:

>100_bases
ATGCTGCGTTAATACGCAATACGAACGAAAGAGTAGGCGTTGTGAATTGTTTGAAATAACAACGTGATGTTACATCATTG
ATATATTGAGTATTACAGTT

Downstream 100 bases:

>100_bases
GTTTTTTATTCAGCACTGTTTTTGATTTATATCAAACAGTGCTTTTTTATTTTTCCTCTTGTGCTAAAAGGGAATAATTT
CTGAGAAAAAGTTGTGTTAT

Product: Mlc

Products: NA

Alternate protein names: Making large colonies protein [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MPKIRKEDKLPLRLTQLGKIYRLVEQFEEISRIDLSKLSRLAPATITALTRELIKEKLIVERAVQNTESRGRPAIGLCVS
PFYWQSLCATLVENRFELILSELDGGEIKSKSYPLTTSDLVHLDQVLVQYLQQFLFETQHELNHLITFSIAVGGELDSKN
RLIKLGDVNLDLDLESLFKPYFKVPVLVTEYFQTWLMAESTLGSVINCDNVLFLQLDDVINFSVLSKGELLTHQHQVRSH
INKMIVPKISPLQDLISPHLADLERYQLQHQVTHKAIYPLITHYFPEAALAQSEIEFLCQKANAQNPQAQQILHYVADSL
AYILMNLVNIFDSEKIMLSSSFLSAKEVFLPRVNQTLKANLGADYPHVEVITGRYEWNTPVVAAAAIKQGIYDGSLLGHF
IKH

Sequences:

>Translated_403_residues
MPKIRKEDKLPLRLTQLGKIYRLVEQFEEISRIDLSKLSRLAPATITALTRELIKEKLIVERAVQNTESRGRPAIGLCVS
PFYWQSLCATLVENRFELILSELDGGEIKSKSYPLTTSDLVHLDQVLVQYLQQFLFETQHELNHLITFSIAVGGELDSKN
RLIKLGDVNLDLDLESLFKPYFKVPVLVTEYFQTWLMAESTLGSVINCDNVLFLQLDDVINFSVLSKGELLTHQHQVRSH
INKMIVPKISPLQDLISPHLADLERYQLQHQVTHKAIYPLITHYFPEAALAQSEIEFLCQKANAQNPQAQQILHYVADSL
AYILMNLVNIFDSEKIMLSSSFLSAKEVFLPRVNQTLKANLGADYPHVEVITGRYEWNTPVVAAAAIKQGIYDGSLLGHF
IKH
>Mature_402_residues
PKIRKEDKLPLRLTQLGKIYRLVEQFEEISRIDLSKLSRLAPATITALTRELIKEKLIVERAVQNTESRGRPAIGLCVSP
FYWQSLCATLVENRFELILSELDGGEIKSKSYPLTTSDLVHLDQVLVQYLQQFLFETQHELNHLITFSIAVGGELDSKNR
LIKLGDVNLDLDLESLFKPYFKVPVLVTEYFQTWLMAESTLGSVINCDNVLFLQLDDVINFSVLSKGELLTHQHQVRSHI
NKMIVPKISPLQDLISPHLADLERYQLQHQVTHKAIYPLITHYFPEAALAQSEIEFLCQKANAQNPQAQQILHYVADSLA
YILMNLVNIFDSEKIMLSSSFLSAKEVFLPRVNQTLKANLGADYPHVEVITGRYEWNTPVVAAAAIKQGIYDGSLLGHFI
KH

Specific function: Transcriptional repressor that regulates the expression of proteins that are part of the phosphotransferase system for sugar uptake. Regulates the expression of malT [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Escherichia coli, GI1787878, Length=402, Percent_Identity=26.1194029850746, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1786891, Length=388, Percent_Identity=22.9381443298969, Blast_Score=117, Evalue=9e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 45833; Mature: 45701

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKIRKEDKLPLRLTQLGKIYRLVEQFEEISRIDLSKLSRLAPATITALTRELIKEKLIV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHHHH
ERAVQNTESRGRPAIGLCVSPFYWQSLCATLVENRFELILSELDGGEIKSKSYPLTTSDL
HHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
VHLDQVLVQYLQQFLFETQHELNHLITFSIAVGGELDSKNRLIKLGDVNLDLDLESLFKP
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCEEEECCCCCCCCHHHHHHH
YFKVPVLVTEYFQTWLMAESTLGSVINCDNVLFLQLDDVINFSVLSKGELLTHQHQVRSH
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHCCCHHHHHHHHHHHH
INKMIVPKISPLQDLISPHLADLERYQLQHQVTHKAIYPLITHYFPEAALAQSEIEFLCQ
HHHHCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
KANAQNPQAQQILHYVADSLAYILMNLVNIFDSEKIMLSSSFLSAKEVFLPRVNQTLKAN
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHCHHHHHC
LGADYPHVEVITGRYEWNTPVVAAAAIKQGIYDGSLLGHFIKH
CCCCCCCEEEEECCEECCCCHHHHHHHHHCCCCHHHHHHHHCC
>Mature Secondary Structure 
PKIRKEDKLPLRLTQLGKIYRLVEQFEEISRIDLSKLSRLAPATITALTRELIKEKLIV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHHHH
ERAVQNTESRGRPAIGLCVSPFYWQSLCATLVENRFELILSELDGGEIKSKSYPLTTSDL
HHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
VHLDQVLVQYLQQFLFETQHELNHLITFSIAVGGELDSKNRLIKLGDVNLDLDLESLFKP
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCEEEECCCCCCCCHHHHHHH
YFKVPVLVTEYFQTWLMAESTLGSVINCDNVLFLQLDDVINFSVLSKGELLTHQHQVRSH
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHCCCHHHHHHHHHHHH
INKMIVPKISPLQDLISPHLADLERYQLQHQVTHKAIYPLITHYFPEAALAQSEIEFLCQ
HHHHCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
KANAQNPQAQQILHYVADSLAYILMNLVNIFDSEKIMLSSSFLSAKEVFLPRVNQTLKAN
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHCHHHHHC
LGADYPHVEVITGRYEWNTPVVAAAAIKQGIYDGSLLGHFIKH
CCCCCCCEEEEECCEECCCCHHHHHHHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7766024; 9097039; 9278503 [H]