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The map label for this gene is moaC

Identifier: 15602489

GI number: 15602489

Start: 726913

End: 727389

Strand: Reverse

Name: moaC

Synonym: PM0624

Alternate gene names: 15602489

Gene position: 727389-726913 (Counterclockwise)

Preceding gene: 15602490

Following gene: 15602488

Centisome position: 32.22

GC content: 45.07

Gene sequence:

>477_bases
ATGAGTACATTTACCCATATTAATTGCCAAGGGGAAGCCAACATGGTGGACGTGTCAGGCAAACAAGAGAGCGTGCGTGA
GGCAAGAGCGGAAGCATTAGTGACAATGTCACCAGAAACGCTGAATATGATTATTTCTGGACAACACCATAAAGGTGATG
TATTTGCTACGGCGCGTATCGCGGGGATTCAGGCGGCGAAACGTACATGGGATTTAATTCCGCTGTGTCATCCTTTGTTA
TTATCTAAAGTAGAAGTGAGCTTAACTCCCGTTGTGGAACGTAACCAAGTGCGTATTGAAAGTCTATGTAGATTGACTGG
CAAAACTGGAGTAGAAATGGAAGCGCTAACCGCCGCTAGCGTTGCTGCACTGACGATTTACGATATGTGCAAGGCGGTGC
AAAAAGACATCGTGATTGAACAAGTGCGTTTGCTTGAAAAGTGCGGTGGAAAATCGGGTCATTTTATTGCGAAATAA

Upstream 100 bases:

>100_bases
ATAGTGGTGTACGCGCAAATTTAGCCAGTATCGGCGGTTAATCATATTTTCTACAAATTGACCGCACTTTTTCTATTTTT
CAACTTAACCATGAGAAATT

Downstream 100 bases:

>100_bases
CAGCGAGACAATATGCTAAACATTTTATTTTTTGCTCAAACCAGAGAACTTATCGGCGTCGATAGCCTTGAATTACCTGC
CACGTTTAAGACAGCAGAGC

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MSTFTHINCQGEANMVDVSGKQESVREARAEALVTMSPETLNMIISGQHHKGDVFATARIAGIQAAKRTWDLIPLCHPLL
LSKVEVSLTPVVERNQVRIESLCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDIVIEQVRLLEKCGGKSGHFIAK

Sequences:

>Translated_158_residues
MSTFTHINCQGEANMVDVSGKQESVREARAEALVTMSPETLNMIISGQHHKGDVFATARIAGIQAAKRTWDLIPLCHPLL
LSKVEVSLTPVVERNQVRIESLCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDIVIEQVRLLEKCGGKSGHFIAK
>Mature_157_residues
STFTHINCQGEANMVDVSGKQESVREARAEALVTMSPETLNMIISGQHHKGDVFATARIAGIQAAKRTWDLIPLCHPLLL
SKVEVSLTPVVERNQVRIESLCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDIVIEQVRLLEKCGGKSGHFIAK

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=155, Percent_Identity=81.2903225806452, Blast_Score=255, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI32566331, Length=153, Percent_Identity=41.1764705882353, Blast_Score=122, Evalue=7e-29,
Organism=Drosophila melanogaster, GI28574490, Length=150, Percent_Identity=55.3333333333333, Blast_Score=154, Evalue=2e-38,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=56.2043795620438, Blast_Score=143, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_PASMU (Q9CN22)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245561.1
- ProteinModelPortal:   Q9CN22
- SMR:   Q9CN22
- GeneID:   1243971
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0624
- NMPDR:   fig|272843.1.peg.624
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- ProtClustDB:   PRK09364
- BioCyc:   PMUL272843:PM0624-MONOMER
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 17202; Mature: 17071

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: ACT_SITE 128-128

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTFTHINCQGEANMVDVSGKQESVREARAEALVTMSPETLNMIISGQHHKGDVFATARI
CCCEEEEEECCCCCEEECCCCHHHHHHHHHHEEEEECCHHEEEEEECCCCCCCEEEEHHH
AGIQAAKRTWDLIPLCHPLLLSKVEVSLTPVVERNQVRIESLCRLTGKTGVEMEALTAAS
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHH
VAALTIYDMCKAVQKDIVIEQVRLLEKCGGKSGHFIAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
STFTHINCQGEANMVDVSGKQESVREARAEALVTMSPETLNMIISGQHHKGDVFATARI
CCEEEEEECCCCCEEECCCCHHHHHHHHHHEEEEECCHHEEEEEECCCCCCCEEEEHHH
AGIQAAKRTWDLIPLCHPLLLSKVEVSLTPVVERNQVRIESLCRLTGKTGVEMEALTAAS
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHH
VAALTIYDMCKAVQKDIVIEQVRLLEKCGGKSGHFIAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100