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The map label for this gene is crp [C]

Identifier: 15602464

GI number: 15602464

Start: 697146

End: 697739

Strand: Direct

Name: crp [C]

Synonym: PM0599

Alternate gene names: 15602464

Gene position: 697146-697739 (Clockwise)

Preceding gene: 15602463

Following gene: 15602465

Centisome position: 30.88

GC content: 36.7

Gene sequence:

>594_bases
ATGGACACGTCAATTGGACCAACCAATTTGCAGCATTGCCAACTGACTTATTTACATCAATTAGCTAAAGGGATGACGGT
TTATCAACAAGGCGAGGTTGCACAAGAGTTTTATTTTGTCAAAGAAGGGCTAGTCGGTTTATATCATACTTTAGATAATG
GTAAAGAGAGCTTAGTTCGCTTATATCGTCAGGGAGACTATTTTGGTTTTCGTACTTTGTTTGGATTAGGTGACAGTCGT
TATCACTGTAGCGCAAAGATCTTAATTGAAGCAGAAGTTATTCGAATCAAGCCAGAAAACATCGATCTATTTTTCTTACA
TAATTTACAACTAAGCAAAGTCTTACTCCAAACGCTTGCCAATGAATTACGGGATGCTGAGCAACGATTAGCGAAAAGTG
CCTATTTACGTACTTTAGATCGTGTCATTGATAGTATGTGTTTTTTAACAAGTAATTTTCCGTATTATAACTGGACTTAT
CGAGAAATCGCCGAATACGCAGGTTGTGAAACAGAAACCGCCATTCGTATTGCAAAAGAATTAAGGCAAAATGGCTTATT
TACTGAATTATTACCTCATCACAAGGGAAAATAA

Upstream 100 bases:

>100_bases
AAGGTAATGAGGTTAACGTTTTTTAGTATTTTTTAAGCGTTAACCTCATTATCTTGAAAGATTTAACCATGAAGAATAAA
TATCACATAAGAAGGAATAT

Downstream 100 bases:

>100_bases
AAGGCGTGTAGTATGGCATTTTTCTCACCTAAAACGAATTTCCATTTGATGGCAAAACCAAGTAGTTTTCATTGTAATAT
TCAATGTGAATATTGTTTTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MDTSIGPTNLQHCQLTYLHQLAKGMTVYQQGEVAQEFYFVKEGLVGLYHTLDNGKESLVRLYRQGDYFGFRTLFGLGDSR
YHCSAKILIEAEVIRIKPENIDLFFLHNLQLSKVLLQTLANELRDAEQRLAKSAYLRTLDRVIDSMCFLTSNFPYYNWTY
REIAEYAGCETETAIRIAKELRQNGLFTELLPHHKGK

Sequences:

>Translated_197_residues
MDTSIGPTNLQHCQLTYLHQLAKGMTVYQQGEVAQEFYFVKEGLVGLYHTLDNGKESLVRLYRQGDYFGFRTLFGLGDSR
YHCSAKILIEAEVIRIKPENIDLFFLHNLQLSKVLLQTLANELRDAEQRLAKSAYLRTLDRVIDSMCFLTSNFPYYNWTY
REIAEYAGCETETAIRIAKELRQNGLFTELLPHHKGK
>Mature_197_residues
MDTSIGPTNLQHCQLTYLHQLAKGMTVYQQGEVAQEFYFVKEGLVGLYHTLDNGKESLVRLYRQGDYFGFRTLFGLGDSR
YHCSAKILIEAEVIRIKPENIDLFFLHNLQLSKVLLQTLANELRDAEQRLAKSAYLRTLDRVIDSMCFLTSNFPYYNWTY
REIAEYAGCETETAIRIAKELRQNGLFTELLPHHKGK

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00027 cNMP_binding [H]

EC number: NA

Molecular weight: Translated: 22823; Mature: 22823

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTSIGPTNLQHCQLTYLHQLAKGMTVYQQGEVAQEFYFVKEGLVGLYHTLDNGKESLVR
CCCCCCCCCCHHHHHHHHHHHHHCCEEHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LYRQGDYFGFRTLFGLGDSRYHCSAKILIEAEVIRIKPENIDLFFLHNLQLSKVLLQTLA
HHHCCCCCHHHHHHCCCCCCEEEEEEEEEEEEEEEECCCCEEEEEEECCHHHHHHHHHHH
NELRDAEQRLAKSAYLRTLDRVIDSMCFLTSNFPYYNWTYREIAEYAGCETETAIRIAKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHH
LRQNGLFTELLPHHKGK
HHHCCCHHHHCCCCCCC
>Mature Secondary Structure
MDTSIGPTNLQHCQLTYLHQLAKGMTVYQQGEVAQEFYFVKEGLVGLYHTLDNGKESLVR
CCCCCCCCCCHHHHHHHHHHHHHCCEEHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LYRQGDYFGFRTLFGLGDSRYHCSAKILIEAEVIRIKPENIDLFFLHNLQLSKVLLQTLA
HHHCCCCCHHHHHHCCCCCCEEEEEEEEEEEEEEEECCCCEEEEEEECCHHHHHHHHHHH
NELRDAEQRLAKSAYLRTLDRVIDSMCFLTSNFPYYNWTYREIAEYAGCETETAIRIAKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHH
LRQNGLFTELLPHHKGK
HHHCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]