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The map label for this gene is putA [H]

Identifier: 15602454

GI number: 15602454

Start: 678919

End: 682515

Strand: Direct

Name: putA [H]

Synonym: PM0589

Alternate gene names: 15602454

Gene position: 678919-682515 (Clockwise)

Preceding gene: 15602453

Following gene: 15602455

Centisome position: 30.07

GC content: 42.9

Gene sequence:

>3597_bases
ATGACATACCAATTACTTCCCAAATTAACTTCATTACGAGAACCATTAAGCCAACATTATCGTATTGACGAAACCACGTT
AGTGCAAAAACTTCTCTCCGACGCAGAAATTCCTTCCGATCTCCAAACCAAAATTCAACAGCTAGCCAGAAAATTGGTCG
AAAATGTACGCAACGCTCGCCAAAATGCAAGTGGGGTAGATGCCTTAATGCATGAGTTTTCATTATCGAGTCAAGAAGGT
GTCGCCTTAATGTGCTTAGCTGAAGCATTATTGCGTATTCCTGATAAAGCCACTGCAGATAAATTGATTCGCGATAAAAT
TTCAAAAGGGAACTGGCGTTCGCATATCGGACAGAGTCCGTCTATGTTTGTGAATGCCGCCGCTTGGGGTTTATTGATTA
CCGGTAAATTAGTTTCGACACACAGTGAACAACAGCTTTCATCCAGTTTAACCAAATTGATTGCGAAAGGCGGAGAACCA
TTGATTCGTAAAGGTGTGGAAGTGGCAATGCGCTTATTAGGTAAACAATTTGTCACTGGGGAAACGATCGAACAAGCGAT
TAAAAACGGTGAAAAACGTTTCCAACAAGGTTTTCGTTATAGCTATGATATGTTGGGCGAAGCTGCCTTAACGGAAGAAG
ATGCCGCACGTTATTATCAAGACTATGTGGATTCCATTCATGCGGTGGGGCAACGTTCTTCTGGGCTTGGCGTTTATGCC
GCCTCTGGTGTCTCGATCAAACTCTCTGCTATTCATCCTCGTTACAGTCTATCACAACACCAACGTGTGATAGACGAACT
GTATCCCAAGGTCAAACAACTCTTTTTATTAGCGAAGCAATATGACATTGGTCTGAATATTGATGCTGAAGAAGCGGACA
GATTAGACATTTCTTTGGATTTAGTCGATCGTTTATTAGCTGATCCTGATTTAGCACATTTTAACGGTATCGGTTTGGTG
GTACAGGCATACCAAAAACGTTGTACTTTTGTCATTGACTATTTAATTGAACAAGCCCGCAAACATCAACATAAAATTAT
GGTACGTTTAGTGAAAGGGGCTTATTGGGACAGCGAAATTAAACGTGCGCAAACCGATGGTGCCGAAGGTTACCCTGTCT
TTACGCGGAAAGTGCATACAGACGTGTCTTACATTGCTTGTGCGAAAAAATTATTAGCGGCACAAGATGTGATTTATCCA
CAATTTGCCACCCATAACGCGCAATCTTTGGCGACGGTCTATCATTTAGCACAAGGTAAACAATTTGAATTCCAATGCTT
ACACGGCATGGGCGAAACCTTATATGATCAAGTGGTGGGAAAACACAATTTGAATGTGCAATGCCGTATTTATGCGCCTG
TCGGTTCATATAAAACCCTGTTGGCTTATTTAGTGCGCCGCTTATTAGAAAATGGGGCAAATAGCTCGTTTGTGAATCAC
ATTGTCGATGACTCAATCCCCGTTGAAGCCTTAATCCTTGATCCAGTGCAAAAAGCGAAAGAAACCGAAGGGACAATGCA
CCCTAAAACACCATTGCCTCGCGATCTCTTTGCTGGAAAGCGTGTAAATTCTAAAGGTTACGATTTAACCGATGCGTTGC
AGTTACAACAGTTACAAAATGCATTAACTGAACTGAGTCAAAATGAATATGAAGCCTATCCTTTATTAGAAAATACCACT
GCACCAACCGGTAAACCGCGTCTTGTATTTAACCCTGCAAAACGTGCAATGCTAGTTGGTAAAGTGATTGACGCCAGAGA
AGAAGATGTCGAACAGGCATTTGAAAATGCGCTTCGTCATAAAGACAACTGGGCCAATACACCGGTAGAACAAAGAGCGG
TCATTTTAGAAAAAATGGCAGATTTAATGGAACAACACATGCCGCAGTTATTTGATTTAGCGGTACGTGAAGCCGGCAAA
ACCTTAAATAACGCCATTGCCGAAGTGCGTGAGGCGGTGGATTTTTGTCGCTATTATGCACAAGAAGCACGTAAACTCGG
CAATGAGAATCCACCACGTGGTATTGTGGTGGCAATTAGCCCTTGGAATTTCCCTTTAGCCATTTTTATTGGCGAAGTTT
GTTCTGCCTTAGTCACAGGTAATGTGGTGATTGCCAAACCAGCAGAACAAACCTCATTAATGGCGCATTTTGCGGTGAAG
TTGTTTCAACAAGCGGGCTTACCGATTGGTGTGTTGCAATGTTTATGTGGTGCAGGAAAAGTGATTGGTGAAAAATTAGT
CTCTGACGCCCGTGTTGATGGCGTCATTTTTACCGGTTCAACAGATACCGCCAAACGCATTAATCAAAATTTAGCAAAAC
ACAACAAACTTATTCCATTGATTGCCGAAACAGGCGGACAAAATGCAATGATTGTGGACAGTTCAGCCTTAGCAGAACAA
GTCGTGCTTGATGTACTCAATTCCGCGTTTGACTCAGCAGGGCAACGTTGTTCTGCATTACGTGTGCTTTATGTGCAACA
CGATGTCGCACCGCATATTTTAACTATGTTAAAAGGGGCAATGGCAGAGTTAAAAGTCGGCAATCCACAACACTTAACCA
CTGATGTGGGACCCGTGATTGATGAAATGGCACAAAAACGCTTATTACAACATATTGAAACCATGCGAACAGTGGCAAAA
GATTGCTATCAAGTGCCAGTTGATCCAGAAATGCAACAACAGGGAATTTTTGTCCCACCGACTTTATTTGAACTCGAAAA
TCTTCATCATTTGAAACACGAAGTGTTCGGTCCCGTGTTACATGTGGTTCGTTTTCATGCTTCAGAATTTAATCAAGTTA
TTGCACAAATCAATTCTACCGGCTTTGGCTTAACCAGTGGCATACACAGTCGTATTGATGAAAGCATTAATCACTGGCTT
GAACAGGTTCACGCGGGGAATCTGTACGTGAATCGTAATACTGTCGGTGCAGTCGTGGGGGTACAAGCCTTTGGTGGAAG
AGGTTTATCTGGAACAGGACCGAAAGCGGGAGGACCGTTCTATTTGCAACGTTTAGTCCATGCAAAACATTGGGCATTAA
CGCCATTGCATTACAATACGCCGCGTGATTTATCTGATTTAGCGGCAAAAGTGCGGTCAATTTTCACTAAATCTGAACAA
GCTCCTTTACTCTCGCTTATTGATCAAGTTGCGCAATGTTCGCCACTAAATACGACCTTTAGAATGCAAGGGATTACTGG
GGAAGAGAATTATCTTACCTTTACACCACGTTCGTTGATTGCCATTGGGAATGGACCATTAGCACAACAAATGCAAGCGT
TGATTGCCGTCGCCGCAGTGGGCGCAACTGCCGTAATCAGTAAATATTCTCAACTTGCGGCTTATGAAAAACGCTTAGCG
GATTATCTGTTTGTTGCTGAAGTGGAAGAATGCGAGGAAATAAGCCAGTTGATTGTTCTCGATCCGATAACGGCCAAGCA
AAAAGCCCAATATGCCGACCGTCCAGGCGCGATCTTGACCTATGTGGAGCAGCTAGATTTAGCGTTGTCCTTGTTCCCAT
TACTGCATGAACAAGCGATCAGCATTAACACCACAGCAGCAGGAGGTAATGCAAGTTTAATGGCAGAAATGGATTAA

Upstream 100 bases:

>100_bases
AGAGTTAGCTTATCAACAGCAAAAATAATCGGTAAAAGAGCGGTATCTTCGGGTGCCGCTTTTTCTATGTTTAATTTGAT
TATGTGAGTGAGAAAGAAAG

Downstream 100 bases:

>100_bases
TCAAGACGGCTTTTATTGTGCAAAAAGTGGGTGCGATGCCCACTTTTTTATTGTATATATAGCTCACTGGTTGAAGACGA
AAGGAAATAAGAAAATGATC

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1198; Mature: 1197

Protein sequence:

>1198_residues
MTYQLLPKLTSLREPLSQHYRIDETTLVQKLLSDAEIPSDLQTKIQQLARKLVENVRNARQNASGVDALMHEFSLSSQEG
VALMCLAEALLRIPDKATADKLIRDKISKGNWRSHIGQSPSMFVNAAAWGLLITGKLVSTHSEQQLSSSLTKLIAKGGEP
LIRKGVEVAMRLLGKQFVTGETIEQAIKNGEKRFQQGFRYSYDMLGEAALTEEDAARYYQDYVDSIHAVGQRSSGLGVYA
ASGVSIKLSAIHPRYSLSQHQRVIDELYPKVKQLFLLAKQYDIGLNIDAEEADRLDISLDLVDRLLADPDLAHFNGIGLV
VQAYQKRCTFVIDYLIEQARKHQHKIMVRLVKGAYWDSEIKRAQTDGAEGYPVFTRKVHTDVSYIACAKKLLAAQDVIYP
QFATHNAQSLATVYHLAQGKQFEFQCLHGMGETLYDQVVGKHNLNVQCRIYAPVGSYKTLLAYLVRRLLENGANSSFVNH
IVDDSIPVEALILDPVQKAKETEGTMHPKTPLPRDLFAGKRVNSKGYDLTDALQLQQLQNALTELSQNEYEAYPLLENTT
APTGKPRLVFNPAKRAMLVGKVIDAREEDVEQAFENALRHKDNWANTPVEQRAVILEKMADLMEQHMPQLFDLAVREAGK
TLNNAIAEVREAVDFCRYYAQEARKLGNENPPRGIVVAISPWNFPLAIFIGEVCSALVTGNVVIAKPAEQTSLMAHFAVK
LFQQAGLPIGVLQCLCGAGKVIGEKLVSDARVDGVIFTGSTDTAKRINQNLAKHNKLIPLIAETGGQNAMIVDSSALAEQ
VVLDVLNSAFDSAGQRCSALRVLYVQHDVAPHILTMLKGAMAELKVGNPQHLTTDVGPVIDEMAQKRLLQHIETMRTVAK
DCYQVPVDPEMQQQGIFVPPTLFELENLHHLKHEVFGPVLHVVRFHASEFNQVIAQINSTGFGLTSGIHSRIDESINHWL
EQVHAGNLYVNRNTVGAVVGVQAFGGRGLSGTGPKAGGPFYLQRLVHAKHWALTPLHYNTPRDLSDLAAKVRSIFTKSEQ
APLLSLIDQVAQCSPLNTTFRMQGITGEENYLTFTPRSLIAIGNGPLAQQMQALIAVAAVGATAVISKYSQLAAYEKRLA
DYLFVAEVEECEEISQLIVLDPITAKQKAQYADRPGAILTYVEQLDLALSLFPLLHEQAISINTTAAGGNASLMAEMD

Sequences:

>Translated_1198_residues
MTYQLLPKLTSLREPLSQHYRIDETTLVQKLLSDAEIPSDLQTKIQQLARKLVENVRNARQNASGVDALMHEFSLSSQEG
VALMCLAEALLRIPDKATADKLIRDKISKGNWRSHIGQSPSMFVNAAAWGLLITGKLVSTHSEQQLSSSLTKLIAKGGEP
LIRKGVEVAMRLLGKQFVTGETIEQAIKNGEKRFQQGFRYSYDMLGEAALTEEDAARYYQDYVDSIHAVGQRSSGLGVYA
ASGVSIKLSAIHPRYSLSQHQRVIDELYPKVKQLFLLAKQYDIGLNIDAEEADRLDISLDLVDRLLADPDLAHFNGIGLV
VQAYQKRCTFVIDYLIEQARKHQHKIMVRLVKGAYWDSEIKRAQTDGAEGYPVFTRKVHTDVSYIACAKKLLAAQDVIYP
QFATHNAQSLATVYHLAQGKQFEFQCLHGMGETLYDQVVGKHNLNVQCRIYAPVGSYKTLLAYLVRRLLENGANSSFVNH
IVDDSIPVEALILDPVQKAKETEGTMHPKTPLPRDLFAGKRVNSKGYDLTDALQLQQLQNALTELSQNEYEAYPLLENTT
APTGKPRLVFNPAKRAMLVGKVIDAREEDVEQAFENALRHKDNWANTPVEQRAVILEKMADLMEQHMPQLFDLAVREAGK
TLNNAIAEVREAVDFCRYYAQEARKLGNENPPRGIVVAISPWNFPLAIFIGEVCSALVTGNVVIAKPAEQTSLMAHFAVK
LFQQAGLPIGVLQCLCGAGKVIGEKLVSDARVDGVIFTGSTDTAKRINQNLAKHNKLIPLIAETGGQNAMIVDSSALAEQ
VVLDVLNSAFDSAGQRCSALRVLYVQHDVAPHILTMLKGAMAELKVGNPQHLTTDVGPVIDEMAQKRLLQHIETMRTVAK
DCYQVPVDPEMQQQGIFVPPTLFELENLHHLKHEVFGPVLHVVRFHASEFNQVIAQINSTGFGLTSGIHSRIDESINHWL
EQVHAGNLYVNRNTVGAVVGVQAFGGRGLSGTGPKAGGPFYLQRLVHAKHWALTPLHYNTPRDLSDLAAKVRSIFTKSEQ
APLLSLIDQVAQCSPLNTTFRMQGITGEENYLTFTPRSLIAIGNGPLAQQMQALIAVAAVGATAVISKYSQLAAYEKRLA
DYLFVAEVEECEEISQLIVLDPITAKQKAQYADRPGAILTYVEQLDLALSLFPLLHEQAISINTTAAGGNASLMAEMD
>Mature_1197_residues
TYQLLPKLTSLREPLSQHYRIDETTLVQKLLSDAEIPSDLQTKIQQLARKLVENVRNARQNASGVDALMHEFSLSSQEGV
ALMCLAEALLRIPDKATADKLIRDKISKGNWRSHIGQSPSMFVNAAAWGLLITGKLVSTHSEQQLSSSLTKLIAKGGEPL
IRKGVEVAMRLLGKQFVTGETIEQAIKNGEKRFQQGFRYSYDMLGEAALTEEDAARYYQDYVDSIHAVGQRSSGLGVYAA
SGVSIKLSAIHPRYSLSQHQRVIDELYPKVKQLFLLAKQYDIGLNIDAEEADRLDISLDLVDRLLADPDLAHFNGIGLVV
QAYQKRCTFVIDYLIEQARKHQHKIMVRLVKGAYWDSEIKRAQTDGAEGYPVFTRKVHTDVSYIACAKKLLAAQDVIYPQ
FATHNAQSLATVYHLAQGKQFEFQCLHGMGETLYDQVVGKHNLNVQCRIYAPVGSYKTLLAYLVRRLLENGANSSFVNHI
VDDSIPVEALILDPVQKAKETEGTMHPKTPLPRDLFAGKRVNSKGYDLTDALQLQQLQNALTELSQNEYEAYPLLENTTA
PTGKPRLVFNPAKRAMLVGKVIDAREEDVEQAFENALRHKDNWANTPVEQRAVILEKMADLMEQHMPQLFDLAVREAGKT
LNNAIAEVREAVDFCRYYAQEARKLGNENPPRGIVVAISPWNFPLAIFIGEVCSALVTGNVVIAKPAEQTSLMAHFAVKL
FQQAGLPIGVLQCLCGAGKVIGEKLVSDARVDGVIFTGSTDTAKRINQNLAKHNKLIPLIAETGGQNAMIVDSSALAEQV
VLDVLNSAFDSAGQRCSALRVLYVQHDVAPHILTMLKGAMAELKVGNPQHLTTDVGPVIDEMAQKRLLQHIETMRTVAKD
CYQVPVDPEMQQQGIFVPPTLFELENLHHLKHEVFGPVLHVVRFHASEFNQVIAQINSTGFGLTSGIHSRIDESINHWLE
QVHAGNLYVNRNTVGAVVGVQAFGGRGLSGTGPKAGGPFYLQRLVHAKHWALTPLHYNTPRDLSDLAAKVRSIFTKSEQA
PLLSLIDQVAQCSPLNTTFRMQGITGEENYLTFTPRSLIAIGNGPLAQQMQALIAVAAVGATAVISKYSQLAAYEKRLAD
YLFVAEVEECEEISQLIVLDPITAKQKAQYADRPGAILTYVEQLDLALSLFPLLHEQAISINTTAAGGNASLMAEMD

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777736, Length=504, Percent_Identity=30.952380952381, Blast_Score=195, Evalue=2e-49,
Organism=Homo sapiens, GI25777734, Length=504, Percent_Identity=30.952380952381, Blast_Score=195, Evalue=2e-49,
Organism=Homo sapiens, GI238859541, Length=470, Percent_Identity=31.2765957446809, Blast_Score=192, Evalue=1e-48,
Organism=Homo sapiens, GI153266822, Length=456, Percent_Identity=28.5087719298246, Blast_Score=181, Evalue=3e-45,
Organism=Homo sapiens, GI21361176, Length=457, Percent_Identity=30.6345733041575, Blast_Score=177, Evalue=5e-44,
Organism=Homo sapiens, GI25777730, Length=440, Percent_Identity=30, Blast_Score=172, Evalue=2e-42,
Organism=Homo sapiens, GI25777724, Length=457, Percent_Identity=29.3216630196937, Blast_Score=171, Evalue=6e-42,
Organism=Homo sapiens, GI25777732, Length=450, Percent_Identity=29.5555555555556, Blast_Score=169, Evalue=2e-41,
Organism=Homo sapiens, GI238814322, Length=424, Percent_Identity=27.5943396226415, Blast_Score=166, Evalue=1e-40,
Organism=Homo sapiens, GI12007648, Length=443, Percent_Identity=28.4424379232506, Blast_Score=166, Evalue=1e-40,
Organism=Homo sapiens, GI188035924, Length=451, Percent_Identity=29.490022172949, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI310128093, Length=449, Percent_Identity=29.6213808463252, Blast_Score=164, Evalue=4e-40,
Organism=Homo sapiens, GI310128103, Length=451, Percent_Identity=29.490022172949, Blast_Score=164, Evalue=5e-40,
Organism=Homo sapiens, GI21614513, Length=429, Percent_Identity=29.1375291375291, Blast_Score=164, Evalue=7e-40,
Organism=Homo sapiens, GI25777728, Length=406, Percent_Identity=30.0492610837438, Blast_Score=162, Evalue=2e-39,
Organism=Homo sapiens, GI310128091, Length=391, Percent_Identity=30.690537084399, Blast_Score=143, Evalue=1e-33,
Organism=Homo sapiens, GI115387104, Length=449, Percent_Identity=25.3897550111359, Blast_Score=142, Evalue=3e-33,
Organism=Homo sapiens, GI4507229, Length=410, Percent_Identity=29.5121951219512, Blast_Score=141, Evalue=5e-33,
Organism=Homo sapiens, GI25952152, Length=430, Percent_Identity=26.5116279069767, Blast_Score=135, Evalue=3e-31,
Organism=Homo sapiens, GI25777721, Length=423, Percent_Identity=28.6052009456265, Blast_Score=132, Evalue=2e-30,
Organism=Homo sapiens, GI25777726, Length=463, Percent_Identity=25.9179265658747, Blast_Score=128, Evalue=4e-29,
Organism=Homo sapiens, GI11095441, Length=424, Percent_Identity=24.5283018867925, Blast_Score=119, Evalue=2e-26,
Organism=Homo sapiens, GI310128087, Length=280, Percent_Identity=30, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI310128089, Length=333, Percent_Identity=30.03003003003, Blast_Score=110, Evalue=6e-24,
Organism=Homo sapiens, GI310128095, Length=317, Percent_Identity=29.9684542586751, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI301500698, Length=429, Percent_Identity=24.7086247086247, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI4502043, Length=342, Percent_Identity=24.8538011695906, Blast_Score=99, Evalue=4e-20,
Organism=Homo sapiens, GI238814371, Length=342, Percent_Identity=24.8538011695906, Blast_Score=99, Evalue=4e-20,
Organism=Homo sapiens, GI71773324, Length=346, Percent_Identity=24.8554913294798, Blast_Score=98, Evalue=4e-20,
Organism=Homo sapiens, GI310128097, Length=264, Percent_Identity=31.0606060606061, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI73695881, Length=348, Percent_Identity=24.7126436781609, Blast_Score=94, Evalue=1e-18,
Organism=Homo sapiens, GI73695879, Length=348, Percent_Identity=24.7126436781609, Blast_Score=94, Evalue=1e-18,
Organism=Homo sapiens, GI206597441, Length=455, Percent_Identity=24.6153846153846, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI206597439, Length=455, Percent_Identity=24.6153846153846, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI22907049, Length=455, Percent_Identity=24.6153846153846, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI310128101, Length=208, Percent_Identity=28.8461538461538, Blast_Score=90, Evalue=1e-17,
Organism=Homo sapiens, GI310128099, Length=208, Percent_Identity=28.8461538461538, Blast_Score=90, Evalue=1e-17,
Organism=Homo sapiens, GI4557303, Length=328, Percent_Identity=24.0853658536585, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI73466520, Length=328, Percent_Identity=24.0853658536585, Blast_Score=83, Evalue=2e-15,
Organism=Escherichia coli, GI1787250, Length=1245, Percent_Identity=52.9317269076305, Blast_Score=1192, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=466, Percent_Identity=30.0429184549356, Blast_Score=173, Evalue=5e-44,
Organism=Escherichia coli, GI1787684, Length=460, Percent_Identity=29.7826086956522, Blast_Score=173, Evalue=6e-44,
Organism=Escherichia coli, GI87081896, Length=465, Percent_Identity=28.8172043010753, Blast_Score=171, Evalue=2e-43,
Organism=Escherichia coli, GI1788042, Length=443, Percent_Identity=30.2483069977427, Blast_Score=164, Evalue=3e-41,
Organism=Escherichia coli, GI87082295, Length=445, Percent_Identity=28.9887640449438, Blast_Score=159, Evalue=1e-39,
Organism=Escherichia coli, GI1787715, Length=448, Percent_Identity=30.1339285714286, Blast_Score=157, Evalue=4e-39,
Organism=Escherichia coli, GI1787558, Length=460, Percent_Identity=28.2608695652174, Blast_Score=155, Evalue=2e-38,
Organism=Escherichia coli, GI1786504, Length=472, Percent_Identity=25.635593220339, Blast_Score=144, Evalue=3e-35,
Organism=Escherichia coli, GI87081926, Length=424, Percent_Identity=24.2924528301887, Blast_Score=126, Evalue=1e-29,
Organism=Escherichia coli, GI1787653, Length=261, Percent_Identity=24.904214559387, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17534447, Length=458, Percent_Identity=30.5676855895196, Blast_Score=191, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI115534176, Length=492, Percent_Identity=30.8943089430894, Blast_Score=174, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI115532534, Length=377, Percent_Identity=31.5649867374005, Blast_Score=171, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17551164, Length=479, Percent_Identity=28.8100208768267, Blast_Score=170, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI17562198, Length=474, Percent_Identity=29.957805907173, Blast_Score=165, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI25144435, Length=462, Percent_Identity=30.5194805194805, Blast_Score=164, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI133930964, Length=433, Percent_Identity=27.9445727482679, Blast_Score=162, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI32564151, Length=406, Percent_Identity=29.064039408867, Blast_Score=154, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI32564736, Length=405, Percent_Identity=30.8641975308642, Blast_Score=149, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI25143874, Length=464, Percent_Identity=27.801724137931, Blast_Score=149, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI25143876, Length=442, Percent_Identity=28.2805429864253, Blast_Score=148, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71986308, Length=468, Percent_Identity=26.4957264957265, Blast_Score=137, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17534119, Length=514, Percent_Identity=26.4591439688716, Blast_Score=133, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI71995606, Length=416, Percent_Identity=24.7596153846154, Blast_Score=124, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71995613, Length=395, Percent_Identity=25.3164556962025, Blast_Score=122, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71990744, Length=297, Percent_Identity=29.2929292929293, Blast_Score=115, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17564084, Length=339, Percent_Identity=25.9587020648968, Blast_Score=103, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI25146391, Length=342, Percent_Identity=25.1461988304094, Blast_Score=103, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI32566756, Length=342, Percent_Identity=24.8538011695906, Blast_Score=103, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI25146394, Length=342, Percent_Identity=25.1461988304094, Blast_Score=103, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6321826, Length=486, Percent_Identity=30.2469135802469, Blast_Score=190, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6323821, Length=437, Percent_Identity=31.350114416476, Blast_Score=189, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6320917, Length=446, Percent_Identity=32.0627802690583, Blast_Score=189, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6324950, Length=461, Percent_Identity=28.4164859002169, Blast_Score=187, Evalue=8e-48,
Organism=Saccharomyces cerevisiae, GI6323822, Length=450, Percent_Identity=30.4444444444444, Blast_Score=182, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6325196, Length=463, Percent_Identity=30.4535637149028, Blast_Score=181, Evalue=6e-46,
Organism=Saccharomyces cerevisiae, GI6319478, Length=448, Percent_Identity=26.3392857142857, Blast_Score=126, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6321828, Length=489, Percent_Identity=23.5173824130879, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6323757, Length=429, Percent_Identity=23.3100233100233, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24668425, Length=448, Percent_Identity=29.9107142857143, Blast_Score=188, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24668417, Length=448, Percent_Identity=29.9107142857143, Blast_Score=188, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24668413, Length=448, Percent_Identity=29.9107142857143, Blast_Score=188, Evalue=2e-47,
Organism=Drosophila melanogaster, GI281362580, Length=470, Percent_Identity=28.936170212766, Blast_Score=176, Evalue=6e-44,
Organism=Drosophila melanogaster, GI62472918, Length=470, Percent_Identity=28.936170212766, Blast_Score=176, Evalue=6e-44,
Organism=Drosophila melanogaster, GI62472926, Length=470, Percent_Identity=28.936170212766, Blast_Score=176, Evalue=6e-44,
Organism=Drosophila melanogaster, GI62472936, Length=470, Percent_Identity=28.936170212766, Blast_Score=176, Evalue=6e-44,
Organism=Drosophila melanogaster, GI21356737, Length=470, Percent_Identity=28.936170212766, Blast_Score=176, Evalue=6e-44,
Organism=Drosophila melanogaster, GI20129399, Length=454, Percent_Identity=29.5154185022026, Blast_Score=172, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24650465, Length=457, Percent_Identity=28.8840262582057, Blast_Score=157, Evalue=4e-38,
Organism=Drosophila melanogaster, GI28574525, Length=500, Percent_Identity=26.8, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24585660, Length=459, Percent_Identity=26.3616557734205, Blast_Score=144, Evalue=3e-34,
Organism=Drosophila melanogaster, GI28571798, Length=444, Percent_Identity=26.5765765765766, Blast_Score=137, Evalue=4e-32,
Organism=Drosophila melanogaster, GI28571796, Length=444, Percent_Identity=26.5765765765766, Blast_Score=137, Evalue=4e-32,
Organism=Drosophila melanogaster, GI28571794, Length=444, Percent_Identity=26.5765765765766, Blast_Score=137, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24666674, Length=456, Percent_Identity=27.1929824561404, Blast_Score=137, Evalue=4e-32,
Organism=Drosophila melanogaster, GI28571802, Length=444, Percent_Identity=26.5765765765766, Blast_Score=137, Evalue=4e-32,
Organism=Drosophila melanogaster, GI28571800, Length=444, Percent_Identity=26.5765765765766, Blast_Score=137, Evalue=4e-32,
Organism=Drosophila melanogaster, GI28571806, Length=444, Percent_Identity=26.5765765765766, Blast_Score=137, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24638878, Length=424, Percent_Identity=26.1792452830189, Blast_Score=114, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24638876, Length=424, Percent_Identity=26.1792452830189, Blast_Score=114, Evalue=5e-25,
Organism=Drosophila melanogaster, GI281360299, Length=366, Percent_Identity=27.3224043715847, Blast_Score=107, Evalue=4e-23,
Organism=Drosophila melanogaster, GI281360297, Length=366, Percent_Identity=27.3224043715847, Blast_Score=107, Evalue=4e-23,
Organism=Drosophila melanogaster, GI281360295, Length=366, Percent_Identity=27.3224043715847, Blast_Score=107, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24586250, Length=366, Percent_Identity=27.3224043715847, Blast_Score=107, Evalue=4e-23,
Organism=Drosophila melanogaster, GI281360301, Length=366, Percent_Identity=27.0491803278689, Blast_Score=107, Evalue=6e-23,
Organism=Drosophila melanogaster, GI45552499, Length=366, Percent_Identity=26.2295081967213, Blast_Score=103, Evalue=8e-22,
Organism=Drosophila melanogaster, GI281360303, Length=366, Percent_Identity=25.9562841530055, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281360293, Length=160, Percent_Identity=30, Blast_Score=71, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 132219; Mature: 132088

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYQLLPKLTSLREPLSQHYRIDETTLVQKLLSDAEIPSDLQTKIQQLARKLVENVRNAR
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
QNASGVDALMHEFSLSSQEGVALMCLAEALLRIPDKATADKLIRDKISKGNWRSHIGQSP
CCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHCCCCC
SMFVNAAAWGLLITGKLVSTHSEQQLSSSLTKLIAKGGEPLIRKGVEVAMRLLGKQFVTG
HHHHHHHHHHHHEECHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCH
ETIEQAIKNGEKRFQQGFRYSYDMLGEAALTEEDAARYYQDYVDSIHAVGQRSSGLGVYA
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
ASGVSIKLSAIHPRYSLSQHQRVIDELYPKVKQLFLLAKQYDIGLNIDAEEADRLDISLD
ECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHH
LVDRLLADPDLAHFNGIGLVVQAYQKRCTFVIDYLIEQARKHQHKIMVRLVKGAYWDSEI
HHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
KRAQTDGAEGYPVFTRKVHTDVSYIACAKKLLAAQDVIYPQFATHNAQSLATVYHLAQGK
HHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHCCC
QFEFQCLHGMGETLYDQVVGKHNLNVQCRIYAPVGSYKTLLAYLVRRLLENGANSSFVNH
CHHHHHHHHCCHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHH
IVDDSIPVEALILDPVQKAKETEGTMHPKTPLPRDLFAGKRVNSKGYDLTDALQLQQLQN
HHCCCCCHHHHHHCHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHH
ALTELSQNEYEAYPLLENTTAPTGKPRLVFNPAKRAMLVGKVIDAREEDVEQAFENALRH
HHHHHHCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
KDNWANTPVEQRAVILEKMADLMEQHMPQLFDLAVREAGKTLNNAIAEVREAVDFCRYYA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEARKLGNENPPRGIVVAISPWNFPLAIFIGEVCSALVTGNVVIAKPAEQTSLMAHFAVK
HHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHH
LFQQAGLPIGVLQCLCGAGKVIGEKLVSDARVDGVIFTGSTDTAKRINQNLAKHNKLIPL
HHHHCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCEEE
IAETGGQNAMIVDSSALAEQVVLDVLNSAFDSAGQRCSALRVLYVQHDVAPHILTMLKGA
EECCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAELKVGNPQHLTTDVGPVIDEMAQKRLLQHIETMRTVAKDCYQVPVDPEMQQQGIFVPP
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCC
TLFELENLHHLKHEVFGPVLHVVRFHASEFNQVIAQINSTGFGLTSGIHSRIDESINHWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
EQVHAGNLYVNRNTVGAVVGVQAFGGRGLSGTGPKAGGPFYLQRLVHAKHWALTPLHYNT
HHHHCCCEEEECCCHHHHEEHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHEECCEECCC
PRDLSDLAAKVRSIFTKSEQAPLLSLIDQVAQCSPLNTTFRMQGITGEENYLTFTPRSLI
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCCEEE
AIGNGPLAQQMQALIAVAAVGATAVISKYSQLAAYEKRLADYLFVAEVEECEEISQLIVL
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
DPITAKQKAQYADRPGAILTYVEQLDLALSLFPLLHEQAISINTTAAGGNASLMAEMD
CCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCEEEECC
>Mature Secondary Structure 
TYQLLPKLTSLREPLSQHYRIDETTLVQKLLSDAEIPSDLQTKIQQLARKLVENVRNAR
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
QNASGVDALMHEFSLSSQEGVALMCLAEALLRIPDKATADKLIRDKISKGNWRSHIGQSP
CCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHCCCCC
SMFVNAAAWGLLITGKLVSTHSEQQLSSSLTKLIAKGGEPLIRKGVEVAMRLLGKQFVTG
HHHHHHHHHHHHEECHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCH
ETIEQAIKNGEKRFQQGFRYSYDMLGEAALTEEDAARYYQDYVDSIHAVGQRSSGLGVYA
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
ASGVSIKLSAIHPRYSLSQHQRVIDELYPKVKQLFLLAKQYDIGLNIDAEEADRLDISLD
ECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHH
LVDRLLADPDLAHFNGIGLVVQAYQKRCTFVIDYLIEQARKHQHKIMVRLVKGAYWDSEI
HHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
KRAQTDGAEGYPVFTRKVHTDVSYIACAKKLLAAQDVIYPQFATHNAQSLATVYHLAQGK
HHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHCCC
QFEFQCLHGMGETLYDQVVGKHNLNVQCRIYAPVGSYKTLLAYLVRRLLENGANSSFVNH
CHHHHHHHHCCHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHH
IVDDSIPVEALILDPVQKAKETEGTMHPKTPLPRDLFAGKRVNSKGYDLTDALQLQQLQN
HHCCCCCHHHHHHCHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHH
ALTELSQNEYEAYPLLENTTAPTGKPRLVFNPAKRAMLVGKVIDAREEDVEQAFENALRH
HHHHHHCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
KDNWANTPVEQRAVILEKMADLMEQHMPQLFDLAVREAGKTLNNAIAEVREAVDFCRYYA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEARKLGNENPPRGIVVAISPWNFPLAIFIGEVCSALVTGNVVIAKPAEQTSLMAHFAVK
HHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHH
LFQQAGLPIGVLQCLCGAGKVIGEKLVSDARVDGVIFTGSTDTAKRINQNLAKHNKLIPL
HHHHCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCEEE
IAETGGQNAMIVDSSALAEQVVLDVLNSAFDSAGQRCSALRVLYVQHDVAPHILTMLKGA
EECCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAELKVGNPQHLTTDVGPVIDEMAQKRLLQHIETMRTVAKDCYQVPVDPEMQQQGIFVPP
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCC
TLFELENLHHLKHEVFGPVLHVVRFHASEFNQVIAQINSTGFGLTSGIHSRIDESINHWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
EQVHAGNLYVNRNTVGAVVGVQAFGGRGLSGTGPKAGGPFYLQRLVHAKHWALTPLHYNT
HHHHCCCEEEECCCHHHHEEHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHEECCEECCC
PRDLSDLAAKVRSIFTKSEQAPLLSLIDQVAQCSPLNTTFRMQGITGEENYLTFTPRSLI
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCCEEE
AIGNGPLAQQMQALIAVAAVGATAVISKYSQLAAYEKRLADYLFVAEVEECEEISQLIVL
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
DPITAKQKAQYADRPGAILTYVEQLDLALSLFPLLHEQAISINTTAAGGNASLMAEMD
CCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]