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The map label for this gene is rlmM

Identifier: 15602433

GI number: 15602433

Start: 653184

End: 654281

Strand: Direct

Name: rlmM

Synonym: PM0568

Alternate gene names: 15602433

Gene position: 653184-654281 (Clockwise)

Preceding gene: 15602432

Following gene: 15602441

Centisome position: 28.93

GC content: 41.44

Gene sequence:

>1098_bases
ATGAATAAATTAGCATTATATTGCCGTCCTGGCTTTGAAAAAGAACTTGCCGCTGAAATCAGTGAAAAAGCGGCTGAACT
GGGCATATTTGGTTTTGCCAGAGTAGAGGAAAATCAAGGCTATGTGATTTTTGAATGTTACCAAACCGACGATGCCGATC
GCCTAGCGCGTGAAATCCCTTTTAATCAACTGATTTTTGCCCGCCAAATGATCGTCGTATCTGACCTTTTAACCGATCTC
CCAGTTCAAGATCGTATTAGTCCGATTATTCAGCAATACCAAGCGATAGCCCATCAAATCAATTTAACATACAGCACCGA
ATTGCTTGTTGAAACAGCCGATACGAATGAGGCAAAATCACTGTCTGCTTTTTGTCGTAAATTTACCGTGCCATTACGCC
AAGCCCTAAAAAAACAAGGTTGGTTACAGGGGACTCGACATCATAAACAAGGGCTGACATTACATATTCTGATGTTAGAT
TCAACTCAATGTTATGTGGGGTATTCTTATAACTATAATCATTCTGAGCATTTTATGGGGATTCCGCGTTTGAAATTTCC
GCTAGATGCGCCAAGCCGTTCAACGTTAAAATTGGAAGAAGCCATTCTGACTTTCCTGTCTAGGGAAGAAGAAAAGAAAC
GTTTGAATGAGCAAATGTATGCTGTGGATTTGGGCGCTTGCCCCGGTGGTTGGACATATCAGCTCGTCAAGCGTGGATTA
TTTGTTTATGCGGTCGATCACGGCAAAATGGCGGCGAGCTTACACGATACCGGACGTATTGAGCATTGTGCGGAAGATGG
CTTTAAATTTCAACCACCGAAACGCAGCAAAATTGATTGGTTAGTCTGTGATATGGTGGAACAACCTAGCCGAATCAGCC
AATTAATCCTCAAATGGTTAGTGAATGGCTGGTGCCATGAAACGATTTTTAATTTGAAATTGCCGATGAAAAAACGCTAT
CTTGAAGTGAAAAAATGTTTGCAGATGATCGAGGAAAGCTTAGAAAAACAGGGATTCCGTTACCATATTCAAGCGAAACA
TTTATATCATGATAGAGAAGAAATTACGGTGCATATTGCCGTCAAGTCGCTGGACTAA

Upstream 100 bases:

>100_bases
ATGATCCTAAATCTTTTTATGTGGTGAATCATTTTGATGTAAATGATGAACGTATCCAAGCATTTCGCGCTTGGATCATT
GAAACAATGAAACAAAAATA

Downstream 100 bases:

>100_bases
CTGATGGATGAACAACACACCGCCTTGATAAAGTGCGGTGTTTTTTTGATTTTTTATGTAAAAGGTAGGGGAGAGGATAC
TATTTATTGCCTGTTTTTAA

Product: putative RNA 2'-O-ribose methyltransferase

Products: NA

Alternate protein names: 23S rRNA 2'-O-ribose methyltransferase rlmM

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MNKLALYCRPGFEKELAAEISEKAAELGIFGFARVEENQGYVIFECYQTDDADRLAREIPFNQLIFARQMIVVSDLLTDL
PVQDRISPIIQQYQAIAHQINLTYSTELLVETADTNEAKSLSAFCRKFTVPLRQALKKQGWLQGTRHHKQGLTLHILMLD
STQCYVGYSYNYNHSEHFMGIPRLKFPLDAPSRSTLKLEEAILTFLSREEEKKRLNEQMYAVDLGACPGGWTYQLVKRGL
FVYAVDHGKMAASLHDTGRIEHCAEDGFKFQPPKRSKIDWLVCDMVEQPSRISQLILKWLVNGWCHETIFNLKLPMKKRY
LEVKKCLQMIEESLEKQGFRYHIQAKHLYHDREEITVHIAVKSLD

Sequences:

>Translated_365_residues
MNKLALYCRPGFEKELAAEISEKAAELGIFGFARVEENQGYVIFECYQTDDADRLAREIPFNQLIFARQMIVVSDLLTDL
PVQDRISPIIQQYQAIAHQINLTYSTELLVETADTNEAKSLSAFCRKFTVPLRQALKKQGWLQGTRHHKQGLTLHILMLD
STQCYVGYSYNYNHSEHFMGIPRLKFPLDAPSRSTLKLEEAILTFLSREEEKKRLNEQMYAVDLGACPGGWTYQLVKRGL
FVYAVDHGKMAASLHDTGRIEHCAEDGFKFQPPKRSKIDWLVCDMVEQPSRISQLILKWLVNGWCHETIFNLKLPMKKRY
LEVKKCLQMIEESLEKQGFRYHIQAKHLYHDREEITVHIAVKSLD
>Mature_365_residues
MNKLALYCRPGFEKELAAEISEKAAELGIFGFARVEENQGYVIFECYQTDDADRLAREIPFNQLIFARQMIVVSDLLTDL
PVQDRISPIIQQYQAIAHQINLTYSTELLVETADTNEAKSLSAFCRKFTVPLRQALKKQGWLQGTRHHKQGLTLHILMLD
STQCYVGYSYNYNHSEHFMGIPRLKFPLDAPSRSTLKLEEAILTFLSREEEKKRLNEQMYAVDLGACPGGWTYQLVKRGL
FVYAVDHGKMAASLHDTGRIEHCAEDGFKFQPPKRSKIDWLVCDMVEQPSRISQLILKWLVNGWCHETIFNLKLPMKKRY
LEVKKCLQMIEESLEKQGFRYHIQAKHLYHDREEITVHIAVKSLD

Specific function: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA

COG id: COG2933

COG function: function code R; Predicted SAM-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmE family. RlmM subfamily

Homologues:

Organism=Escherichia coli, GI1789171, Length=359, Percent_Identity=59.0529247910863, Blast_Score=441, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMM_PASMU (Q9CN71)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245505.1
- ProteinModelPortal:   Q9CN71
- SMR:   Q9CN71
- GeneID:   1243915
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0568
- NMPDR:   fig|272843.1.peg.568
- HOGENOM:   HBG681972
- OMA:   LYCRPGF
- ProtClustDB:   PRK11760
- BioCyc:   PMUL272843:PM0568-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01551
- InterPro:   IPR011224
- InterPro:   IPR002877
- PIRSF:   PIRSF028774

Pfam domain/function: PF01728 FtsJ

EC number: NA

Molecular weight: Translated: 42289; Mature: 42289

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLALYCRPGFEKELAAEISEKAAELGIFGFARVEENQGYVIFECYQTDDADRLAREIP
CCCEEEEECCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCEEEEEEECCCCHHHHHHHCC
FNQLIFARQMIVVSDLLTDLPVQDRISPIIQQYQAIAHQINLTYSTELLVETADTNEAKS
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCHHH
LSAFCRKFTVPLRQALKKQGWLQGTRHHKQGLTLHILMLDSTQCYVGYSYNYNHSEHFMG
HHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCEEEEEEEECCEEEEEEEECCCCCHHCCC
IPRLKFPLDAPSRSTLKLEEAILTFLSREEEKKRLNEQMYAVDLGACPGGWTYQLVKRGL
CCCEECCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHEEEEEECCCCCCCHHHHHHCCE
FVYAVDHGKMAASLHDTGRIEHCAEDGFKFQPPKRSKIDWLVCDMVEQPSRISQLILKWL
EEEEEECCCEEECCCCCCCHHHHHHCCCCCCCCCCCCCCEEEHHHHHCHHHHHHHHHHHH
VNGWCHETIFNLKLPMKKRYLEVKKCLQMIEESLEKQGFRYHIQAKHLYHDREEITVHIA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHCCCCEEEEEEE
VKSLD
EEECC
>Mature Secondary Structure
MNKLALYCRPGFEKELAAEISEKAAELGIFGFARVEENQGYVIFECYQTDDADRLAREIP
CCCEEEEECCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCEEEEEEECCCCHHHHHHHCC
FNQLIFARQMIVVSDLLTDLPVQDRISPIIQQYQAIAHQINLTYSTELLVETADTNEAKS
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCHHH
LSAFCRKFTVPLRQALKKQGWLQGTRHHKQGLTLHILMLDSTQCYVGYSYNYNHSEHFMG
HHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCEEEEEEEECCEEEEEEEECCCCCHHCCC
IPRLKFPLDAPSRSTLKLEEAILTFLSREEEKKRLNEQMYAVDLGACPGGWTYQLVKRGL
CCCEECCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHEEEEEECCCCCCCHHHHHHCCE
FVYAVDHGKMAASLHDTGRIEHCAEDGFKFQPPKRSKIDWLVCDMVEQPSRISQLILKWL
EEEEEECCCEEECCCCCCCHHHHHHCCCCCCCCCCCCCCEEEHHHHHCHHHHHHHHHHHH
VNGWCHETIFNLKLPMKKRYLEVKKCLQMIEESLEKQGFRYHIQAKHLYHDREEITVHIA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHCCCCEEEEEEE
VKSLD
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100