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The map label for this gene is lolC [H]

Identifier: 15602425

GI number: 15602425

Start: 643622

End: 644812

Strand: Direct

Name: lolC [H]

Synonym: PM0560

Alternate gene names: 15602425

Gene position: 643622-644812 (Clockwise)

Preceding gene: 15602424

Following gene: 15602426

Centisome position: 28.51

GC content: 40.13

Gene sequence:

>1191_bases
ATGAAATTTTCTGTTCCTTTATTCATTGCATTGCGTTACTGGCGAGCAAAAAGTGCGGACCGTTTTGGACGTCTGGTTAC
CAATCTGGCCAGTATTGGTATTGTGTTGGGCGTGATGGCATTGATCATTGTGTTGTCTGTGATGAATGGCTTAGAACAAC
ATCAAAAGAAGCATGTCTTAGCAAACATTCCACACGCTATTGTTATGCCAGTAACACAACGCATTACATTAACAGATGAA
ATGATTGCATTACCGCCTTTTGTGCAAAAAGCGGTGCCGATCAATCAAACACAAGTGATTTTACAAACGGCAACAGGCGT
GAGTGCAGGTCAAGTCATTGGTGTACAACAATCGGCTGATGATCCTTTATTAATGGATATGTTGAGCCCTGATTTTGAAC
AAATTCTACCACCAGGTGCCTTTAATTTAGTGATTGGGGCGCAACTCGCACAAAAATTACAGCTACATATTGGCGATAAA
GTGCGCTTGATGATGACAGAAAACAGTCAATATACCCCTTTCGGTCGCGTTCCCGTACAACGTCTGTTTACGGTCAGTGA
TATTTATTATTCAGGAGATGAAGCATCGAGTTATGAAGTTTTTGCTCATTTATCTGATATTGGACGTTTAATGCGCATTC
AACCTGAGCTGGCACAAGGCTATCGTTTATTTCTGCAAGACCCTTTCCAAATTACTGAACTTCCACAATATTTTGCTGAG
CAATCTTGGCAATTATACGACTGGCGTCAACAAAAAGGCGAATTTTTCCAAGCGGTGCGTATGGAAAAAAACATGATGGG
ACTCTTAATTAGCTTAATTATTGTTGTGGCAGTTTCTAATATTGTGACATCACTTAGCCTTATGGTCGTGGATAAACAAG
GCGAGATCGCGATTTTACAAACACAAGGACTTAATAAACGCCAAGTGCGGTCGATTTTTATTTATCAAGGTTGTTTGGTC
GGCTTTGTTGGTACCGTGATTGGTGCCATATTAGGTGTTCTCGTGACGCTAAACTTAGATAGGCTAGTCGGTTGGTTCAA
TTCTGCGGATATTTATTTACCGACGGCATTTGATCCGCTCCAGTTCATGATTATTTTATTTTTTTCGTTATTATTATCTT
TAATTTCCACAATTTATCCTGCTTATCGTGCAGCGCAAATTGATCCAGCAGAAGCACTACGTTATGAATAA

Upstream 100 bases:

>100_bases
AAATGAGCAGATTGCTTAACTAAATTAAATATCGTGATGTTGTTGTATGTTGTTTATGCAATAATAGCACGATATTTTTT
ATGACTTGATTTTGGTAAAA

Downstream 100 bases:

>100_bases
GAAGGCAAACTTGGATATGAAATCACACTTATTACATTGTCAGCATATTACAAAATATTATCAAGAAGGCTCACAACAGA
CACAAGTTTTAAAAGACGTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MKFSVPLFIALRYWRAKSADRFGRLVTNLASIGIVLGVMALIIVLSVMNGLEQHQKKHVLANIPHAIVMPVTQRITLTDE
MIALPPFVQKAVPINQTQVILQTATGVSAGQVIGVQQSADDPLLMDMLSPDFEQILPPGAFNLVIGAQLAQKLQLHIGDK
VRLMMTENSQYTPFGRVPVQRLFTVSDIYYSGDEASSYEVFAHLSDIGRLMRIQPELAQGYRLFLQDPFQITELPQYFAE
QSWQLYDWRQQKGEFFQAVRMEKNMMGLLISLIIVVAVSNIVTSLSLMVVDKQGEIAILQTQGLNKRQVRSIFIYQGCLV
GFVGTVIGAILGVLVTLNLDRLVGWFNSADIYLPTAFDPLQFMIILFFSLLLSLISTIYPAYRAAQIDPAEALRYE

Sequences:

>Translated_396_residues
MKFSVPLFIALRYWRAKSADRFGRLVTNLASIGIVLGVMALIIVLSVMNGLEQHQKKHVLANIPHAIVMPVTQRITLTDE
MIALPPFVQKAVPINQTQVILQTATGVSAGQVIGVQQSADDPLLMDMLSPDFEQILPPGAFNLVIGAQLAQKLQLHIGDK
VRLMMTENSQYTPFGRVPVQRLFTVSDIYYSGDEASSYEVFAHLSDIGRLMRIQPELAQGYRLFLQDPFQITELPQYFAE
QSWQLYDWRQQKGEFFQAVRMEKNMMGLLISLIIVVAVSNIVTSLSLMVVDKQGEIAILQTQGLNKRQVRSIFIYQGCLV
GFVGTVIGAILGVLVTLNLDRLVGWFNSADIYLPTAFDPLQFMIILFFSLLLSLISTIYPAYRAAQIDPAEALRYE
>Mature_396_residues
MKFSVPLFIALRYWRAKSADRFGRLVTNLASIGIVLGVMALIIVLSVMNGLEQHQKKHVLANIPHAIVMPVTQRITLTDE
MIALPPFVQKAVPINQTQVILQTATGVSAGQVIGVQQSADDPLLMDMLSPDFEQILPPGAFNLVIGAQLAQKLQLHIGDK
VRLMMTENSQYTPFGRVPVQRLFTVSDIYYSGDEASSYEVFAHLSDIGRLMRIQPELAQGYRLFLQDPFQITELPQYFAE
QSWQLYDWRQQKGEFFQAVRMEKNMMGLLISLIIVVAVSNIVTSLSLMVVDKQGEIAILQTQGLNKRQVRSIFIYQGCLV
GFVGTVIGAILGVLVTLNLDRLVGWFNSADIYLPTAFDPLQFMIILFFSLLLSLISTIYPAYRAAQIDPAEALRYE

Specific function: Part of an ATP-dependent transport system lolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprote

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787360, Length=408, Percent_Identity=43.6274509803922, Blast_Score=310, Evalue=1e-85,
Organism=Escherichia coli, GI1787362, Length=414, Percent_Identity=30.4347826086957, Blast_Score=139, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44358; Mature: 44358

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFSVPLFIALRYWRAKSADRFGRLVTNLASIGIVLGVMALIIVLSVMNGLEQHQKKHVL
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANIPHAIVMPVTQRITLTDEMIALPPFVQKAVPINQTQVILQTATGVSAGQVIGVQQSAD
HCCCCCEEECCHHEEEECHHHHHCCHHHHHCCCCCHHHEEEEECCCCCCCCEEEECCCCC
DPLLMDMLSPDFEQILPPGAFNLVIGAQLAQKLQLHIGDKVRLMMTENSQYTPFGRVPVQ
CCHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHH
RLFTVSDIYYSGDEASSYEVFAHLSDIGRLMRIQPELAQGYRLFLQDPFQITELPQYFAE
HHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHCCHHHHCCHHHHHCCCCHHHHHHHHHHH
QSWQLYDWRQQKGEFFQAVRMEKNMMGLLISLIIVVAVSNIVTSLSLMVVDKQGEIAILQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEE
TQGLNKRQVRSIFIYQGCLVGFVGTVIGAILGVLVTLNLDRLVGWFNSADIYLPTAFDPL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCEEECCCCCHH
QFMIILFFSLLLSLISTIYPAYRAAQIDPAEALRYE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCC
>Mature Secondary Structure
MKFSVPLFIALRYWRAKSADRFGRLVTNLASIGIVLGVMALIIVLSVMNGLEQHQKKHVL
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANIPHAIVMPVTQRITLTDEMIALPPFVQKAVPINQTQVILQTATGVSAGQVIGVQQSAD
HCCCCCEEECCHHEEEECHHHHHCCHHHHHCCCCCHHHEEEEECCCCCCCCEEEECCCCC
DPLLMDMLSPDFEQILPPGAFNLVIGAQLAQKLQLHIGDKVRLMMTENSQYTPFGRVPVQ
CCHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHH
RLFTVSDIYYSGDEASSYEVFAHLSDIGRLMRIQPELAQGYRLFLQDPFQITELPQYFAE
HHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHCCHHHHCCHHHHHCCCCHHHHHHHHHHH
QSWQLYDWRQQKGEFFQAVRMEKNMMGLLISLIIVVAVSNIVTSLSLMVVDKQGEIAILQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEE
TQGLNKRQVRSIFIYQGCLVGFVGTVIGAILGVLVTLNLDRLVGWFNSADIYLPTAFDPL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCEEECCCCCHH
QFMIILFFSLLLSLISTIYPAYRAAQIDPAEALRYE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]