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The map label for this gene is ppc

Identifier: 15602411

GI number: 15602411

Start: 628288

End: 630927

Strand: Reverse

Name: ppc

Synonym: PM0546

Alternate gene names: 15602411

Gene position: 630927-628288 (Counterclockwise)

Preceding gene: 15602412

Following gene: 15602401

Centisome position: 27.95

GC content: 44.05

Gene sequence:

>2640_bases
ATGATTCAGCAGTATTCTACTATGCGTAATAATATCAGTATGTTAGGACGTTTTTTAGGCGAAACCATTAGTGATGCACA
AGGTAGTGACATTCTGGAGTTAATTGAAAACATCCGTGTCCTTTCACGTAACTCCCGCCATGGGGATGATCAAGCACGTA
ATGCGTTATTAAACACCTTAGCGACTATCTCTAACGAAAACATTATCCCTGTGGCTCGCGCATTTAGCCAATTCCTCAAT
CTAACCAATATTGCTGAACAATATCAGACGATTTCTCGTCACCACCACGATCATGTTGCTTCTGAGCGCTCTATTTCGGC
CCTTTTTAAACGCTTAAAAGCGCAACAGGTGCCCAAAGAAAACGTCATGGAAACCGTGCAAAAATTATTAATTGAACTGG
TCTTAACGGCCCATCCCACTGAAGTAACGCGTCGTTCCCTAGTCCATAAACATGTCGAAATTAATAAATGTTTAAGTAAA
TTAGAACATACTGATTTAACCGACGCTGAGCGTAAAGCCATTGAACGCCGTTTATTACAGTTGATCGCACAGGCTTGGCA
TACCAACGAAATTCGTACCCAACGTCCTACCCCCTTTGAAGAAGCAAAATGGGGATTTGCCGTCATAGAAAACAGTTTAT
GGCAGGCGGTGCCTGAATTTCTGCGCCATTTAAATACTAGTGCGGTCGAATATTTTGGTTTTCATTTACCCGTTGAACTC
AATCCAATTCGTTTTTCCTCTTGGATGGGAGGCGATCGTGACGGGAATCCTTTTGTCACCGCTGAAGTAACCCGTCAAGT
ATTGCGCTTAGCCCGTTGGAAAGCTGCCGATCTCTTTTTAACCGACATTCAAGCCCTATCTGATGAACTTTCGGTAGTAA
AATGTACCCCTGAATTCCAAGCCAAATACGGCTCACATGTGGAACCTTACCGCACTGTTGTAAAAGCATTACGGAGCAAG
CTTACTGCAACACTAGCCTATTACGATGATCTCTTAGCTAACCGTACACCACGTGTTGCTGAAGAAGACATCATTACGCA
AGATGCACAACTTTGGGAACCGCTTTATGATTGCTATCAATCTTTACAAGCCTGTGGCATGCGCATCATTGCTAACGGAT
TATTACTCGATTGTTTACGCCGTATTCGTTGCTTTGGCGTAACACTTTCTCGCTTAGATATTCGTCAAGAAAGTACCCGT
CATGCAGAAGCGATTGCGGAAATCACACGCTATATCGGTTTAGGCGATTATGCGCAATGGAGTGAGAGTGATAAACAAGC
CTTTTTAATCAAAGAACTGAGTTCACGTCGTCCATTATTACCAAGAGAATGGCAACCTTCTGCCGCAACGCAAGAAGTGT
TGGATACCTGCCGTGTCATTGCTGAACAGCCTGAAGGGGTAATTTCTTGTTACATTATTTCTATGGCAAAAACTGCCTCA
GATGTGCTTGCTGTACATTTATTACTGAAAGAATCTGGCGTGCCTTACCATCTCCCTGTGGTGCCGTTGTTTGAAACCTT
AGATGATCTTCGCGCCTCAGAACAAGTCATGTCCGAACTCTTCAATATTGGTTGGTACCGTGGTGTCATCAATAATAAAC
AAATGGTGATGATTGGTTATTCGGATTCTGCCAAAGATGCGGGGATGATGGCGGCCTCTTGGGCACAATACTGTGCACAA
GAAGCCTTGGTCAACCTCTGCGATAAATGCAATATTGAACTCACTTTATTCCATGGTCGTGGCGGTACCATTGGACGCGG
TGGGGCACCAGCCCATGCTGCCTTACTTTCACAGCCACCTCGCTCATTAAAAAATGGATTACGAGTTACAGAGCAAGGGG
AAATGATTCGTTTTAAATTGGGTTTACCCGCCGTTGCCGTAGAAAGTTTGGGCTTATATGCCAGTGCAATTTTAGAAGCC
AATCTCCTTCCCCCACCAGAACCTAAAGCACAATGGCGGACAGTGATGGATGAGCTGTCCACTATCTCTTGCCAGATTTA
CCGCGATGTCGTACGGGGTGAAAAAGATTTCGTGCCTTATTTTCGTGCAGCGACGCCAGAACAAGAATTATCCAAATTAC
CTTTAGGCTCGCGCCCCGCTAAACGTAATCCAAATGGCGGTGTAGAAAGCTTACGCGCTATTCCATGGATTTTCGCCTGG
ATGCAAAACCGCTTGATGTTACCCGCTTGGTTAGGGGCAGGCGCCTCTCTTCGTCAAGCGATTGAAAAAGGACAAAAAAC
TGTTATTGAAGACATGTGTAAAACGTGGCCATTTTTCTCCACGCGTATTGGAATGTTAGAAATGGTCTTTAGTAAAACGG
ATACTTGGCTTTCTGAACATTATGATCAACACTTGGTTGACCCCGCACTCTGGTATTTAGGCGAATCTTTGCGTGAGCAA
TTAAAACAGGACATTCAAACGGTCTTATCTCTTTCTCACGAAGATCAATTAATGTCCGATTTACCTTGGATTGCAGAATC
TATTGCATTACGTAATGTGTATACTGATCCGCTCAATTTGTTACAAGTGGAACTTTTACGCCGGTTAAGACGTAATCCTG
ACAATCCAAATCCAGATGTGGAACAAGCGTTAATGATCACCATTACCGGTGTCGCAGCCGGTATGCGTAATACGGGTTAA

Upstream 100 bases:

>100_bases
TTATCATTGATCTTTCAAAGTATTTTTGTTTATATCTTGCTTAGTCGAGGTATTTTACCTTTCATTCGTTGAAATCGAGG
ATTATTCAGAGAGGCTTTTT

Downstream 100 bases:

>100_bases
GTCAAACAAAAAGCCACAGTCTTGTTACTGTGGCTTCTTCTTTTCTCAACCAAGTGCGGTGAAAATCGTTTAGTTTTTAC
CGCACTTTTATGTCAGCAAG

Product: phosphoenolpyruvate carboxylase

Products: NA

Alternate protein names: PEPC; PEPCase

Number of amino acids: Translated: 879; Mature: 879

Protein sequence:

>879_residues
MIQQYSTMRNNISMLGRFLGETISDAQGSDILELIENIRVLSRNSRHGDDQARNALLNTLATISNENIIPVARAFSQFLN
LTNIAEQYQTISRHHHDHVASERSISALFKRLKAQQVPKENVMETVQKLLIELVLTAHPTEVTRRSLVHKHVEINKCLSK
LEHTDLTDAERKAIERRLLQLIAQAWHTNEIRTQRPTPFEEAKWGFAVIENSLWQAVPEFLRHLNTSAVEYFGFHLPVEL
NPIRFSSWMGGDRDGNPFVTAEVTRQVLRLARWKAADLFLTDIQALSDELSVVKCTPEFQAKYGSHVEPYRTVVKALRSK
LTATLAYYDDLLANRTPRVAEEDIITQDAQLWEPLYDCYQSLQACGMRIIANGLLLDCLRRIRCFGVTLSRLDIRQESTR
HAEAIAEITRYIGLGDYAQWSESDKQAFLIKELSSRRPLLPREWQPSAATQEVLDTCRVIAEQPEGVISCYIISMAKTAS
DVLAVHLLLKESGVPYHLPVVPLFETLDDLRASEQVMSELFNIGWYRGVINNKQMVMIGYSDSAKDAGMMAASWAQYCAQ
EALVNLCDKCNIELTLFHGRGGTIGRGGAPAHAALLSQPPRSLKNGLRVTEQGEMIRFKLGLPAVAVESLGLYASAILEA
NLLPPPEPKAQWRTVMDELSTISCQIYRDVVRGEKDFVPYFRAATPEQELSKLPLGSRPAKRNPNGGVESLRAIPWIFAW
MQNRLMLPAWLGAGASLRQAIEKGQKTVIEDMCKTWPFFSTRIGMLEMVFSKTDTWLSEHYDQHLVDPALWYLGESLREQ
LKQDIQTVLSLSHEDQLMSDLPWIAESIALRNVYTDPLNLLQVELLRRLRRNPDNPNPDVEQALMITITGVAAGMRNTG

Sequences:

>Translated_879_residues
MIQQYSTMRNNISMLGRFLGETISDAQGSDILELIENIRVLSRNSRHGDDQARNALLNTLATISNENIIPVARAFSQFLN
LTNIAEQYQTISRHHHDHVASERSISALFKRLKAQQVPKENVMETVQKLLIELVLTAHPTEVTRRSLVHKHVEINKCLSK
LEHTDLTDAERKAIERRLLQLIAQAWHTNEIRTQRPTPFEEAKWGFAVIENSLWQAVPEFLRHLNTSAVEYFGFHLPVEL
NPIRFSSWMGGDRDGNPFVTAEVTRQVLRLARWKAADLFLTDIQALSDELSVVKCTPEFQAKYGSHVEPYRTVVKALRSK
LTATLAYYDDLLANRTPRVAEEDIITQDAQLWEPLYDCYQSLQACGMRIIANGLLLDCLRRIRCFGVTLSRLDIRQESTR
HAEAIAEITRYIGLGDYAQWSESDKQAFLIKELSSRRPLLPREWQPSAATQEVLDTCRVIAEQPEGVISCYIISMAKTAS
DVLAVHLLLKESGVPYHLPVVPLFETLDDLRASEQVMSELFNIGWYRGVINNKQMVMIGYSDSAKDAGMMAASWAQYCAQ
EALVNLCDKCNIELTLFHGRGGTIGRGGAPAHAALLSQPPRSLKNGLRVTEQGEMIRFKLGLPAVAVESLGLYASAILEA
NLLPPPEPKAQWRTVMDELSTISCQIYRDVVRGEKDFVPYFRAATPEQELSKLPLGSRPAKRNPNGGVESLRAIPWIFAW
MQNRLMLPAWLGAGASLRQAIEKGQKTVIEDMCKTWPFFSTRIGMLEMVFSKTDTWLSEHYDQHLVDPALWYLGESLREQ
LKQDIQTVLSLSHEDQLMSDLPWIAESIALRNVYTDPLNLLQVELLRRLRRNPDNPNPDVEQALMITITGVAAGMRNTG
>Mature_879_residues
MIQQYSTMRNNISMLGRFLGETISDAQGSDILELIENIRVLSRNSRHGDDQARNALLNTLATISNENIIPVARAFSQFLN
LTNIAEQYQTISRHHHDHVASERSISALFKRLKAQQVPKENVMETVQKLLIELVLTAHPTEVTRRSLVHKHVEINKCLSK
LEHTDLTDAERKAIERRLLQLIAQAWHTNEIRTQRPTPFEEAKWGFAVIENSLWQAVPEFLRHLNTSAVEYFGFHLPVEL
NPIRFSSWMGGDRDGNPFVTAEVTRQVLRLARWKAADLFLTDIQALSDELSVVKCTPEFQAKYGSHVEPYRTVVKALRSK
LTATLAYYDDLLANRTPRVAEEDIITQDAQLWEPLYDCYQSLQACGMRIIANGLLLDCLRRIRCFGVTLSRLDIRQESTR
HAEAIAEITRYIGLGDYAQWSESDKQAFLIKELSSRRPLLPREWQPSAATQEVLDTCRVIAEQPEGVISCYIISMAKTAS
DVLAVHLLLKESGVPYHLPVVPLFETLDDLRASEQVMSELFNIGWYRGVINNKQMVMIGYSDSAKDAGMMAASWAQYCAQ
EALVNLCDKCNIELTLFHGRGGTIGRGGAPAHAALLSQPPRSLKNGLRVTEQGEMIRFKLGLPAVAVESLGLYASAILEA
NLLPPPEPKAQWRTVMDELSTISCQIYRDVVRGEKDFVPYFRAATPEQELSKLPLGSRPAKRNPNGGVESLRAIPWIFAW
MQNRLMLPAWLGAGASLRQAIEKGQKTVIEDMCKTWPFFSTRIGMLEMVFSKTDTWLSEHYDQHLVDPALWYLGESLREQ
LKQDIQTVLSLSHEDQLMSDLPWIAESIALRNVYTDPLNLLQVELLRRLRRNPDNPNPDVEQALMITITGVAAGMRNTG

Specific function: Through the carboxylation of phosphoenolpyruvate (PEP) it forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle

COG id: COG2352

COG function: function code C; Phosphoenolpyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PEPCase type 1 family

Homologues:

Organism=Escherichia coli, GI1790393, Length=886, Percent_Identity=64.8984198645598, Blast_Score=1177, Evalue=0.0,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): CAPP_PASMU (Q9CN89)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245483.1
- ProteinModelPortal:   Q9CN89
- SMR:   Q9CN89
- GeneID:   1243893
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0546
- NMPDR:   fig|272843.1.peg.546
- HOGENOM:   HBG351035
- OMA:   AIPWVFG
- ProtClustDB:   PRK00009
- BioCyc:   PMUL272843:PM0546-MONOMER
- BRENDA:   4.1.1.31
- HAMAP:   MF_00595
- InterPro:   IPR021135
- InterPro:   IPR018129
- InterPro:   IPR022805
- InterPro:   IPR015813
- PRINTS:   PR00150

Pfam domain/function: PF00311 PEPcase; SSF51621 Pyrv/PenolPyrv_Kinase_cat

EC number: =4.1.1.31

Molecular weight: Translated: 99398; Mature: 99398

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00781 PEPCASE_1; PS00393 PEPCASE_2

Important sites: ACT_SITE 138-138 ACT_SITE 545-545

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQQYSTMRNNISMLGRFLGETISDAQGSDILELIENIRVLSRNSRHGDDQARNALLNTL
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
ATISNENIIPVARAFSQFLNLTNIAEQYQTISRHHHDHVASERSISALFKRLKAQQVPKE
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
NVMETVQKLLIELVLTAHPTEVTRRSLVHKHVEINKCLSKLEHTDLTDAERKAIERRLLQ
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LIAQAWHTNEIRTQRPTPFEEAKWGFAVIENSLWQAVPEFLRHLNTSAVEYFGFHLPVEL
HHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCEEE
NPIRFSSWMGGDRDGNPFVTAEVTRQVLRLARWKAADLFLTDIQALSDELSVVKCTPEFQ
CCEEECCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHH
AKYGSHVEPYRTVVKALRSKLTATLAYYDDLLANRTPRVAEEDIITQDAQLWEPLYDCYQ
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
SLQACGMRIIANGLLLDCLRRIRCFGVTLSRLDIRQESTRHAEAIAEITRYIGLGDYAQW
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHC
SESDKQAFLIKELSSRRPLLPREWQPSAATQEVLDTCRVIAEQPEGVISCYIISMAKTAS
CCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
DVLAVHLLLKESGVPYHLPVVPLFETLDDLRASEQVMSELFNIGWYRGVINNKQMVMIGY
HHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
SDSAKDAGMMAASWAQYCAQEALVNLCDKCNIELTLFHGRGGTIGRGGAPAHAALLSQPP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCHHHHHHCCCC
RSLKNGLRVTEQGEMIRFKLGLPAVAVESLGLYASAILEANLLPPPEPKAQWRTVMDELS
HHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
TISCQIYRDVVRGEKDFVPYFRAATPEQELSKLPLGSRPAKRNPNGGVESLRAIPWIFAW
HHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
MQNRLMLPAWLGAGASLRQAIEKGQKTVIEDMCKTWPFFSTRIGMLEMVFSKTDTWLSEH
HHCCEECHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
YDQHLVDPALWYLGESLREQLKQDIQTVLSLSHEDQLMSDLPWIAESIALRNVYTDPLNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LQVELLRRLRRNPDNPNPDVEQALMITITGVAAGMRNTG
HHHHHHHHHHCCCCCCCCCHHHHHHHEEHHHHHCCCCCC
>Mature Secondary Structure
MIQQYSTMRNNISMLGRFLGETISDAQGSDILELIENIRVLSRNSRHGDDQARNALLNTL
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
ATISNENIIPVARAFSQFLNLTNIAEQYQTISRHHHDHVASERSISALFKRLKAQQVPKE
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
NVMETVQKLLIELVLTAHPTEVTRRSLVHKHVEINKCLSKLEHTDLTDAERKAIERRLLQ
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LIAQAWHTNEIRTQRPTPFEEAKWGFAVIENSLWQAVPEFLRHLNTSAVEYFGFHLPVEL
HHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCEEE
NPIRFSSWMGGDRDGNPFVTAEVTRQVLRLARWKAADLFLTDIQALSDELSVVKCTPEFQ
CCEEECCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHH
AKYGSHVEPYRTVVKALRSKLTATLAYYDDLLANRTPRVAEEDIITQDAQLWEPLYDCYQ
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
SLQACGMRIIANGLLLDCLRRIRCFGVTLSRLDIRQESTRHAEAIAEITRYIGLGDYAQW
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHC
SESDKQAFLIKELSSRRPLLPREWQPSAATQEVLDTCRVIAEQPEGVISCYIISMAKTAS
CCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
DVLAVHLLLKESGVPYHLPVVPLFETLDDLRASEQVMSELFNIGWYRGVINNKQMVMIGY
HHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
SDSAKDAGMMAASWAQYCAQEALVNLCDKCNIELTLFHGRGGTIGRGGAPAHAALLSQPP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCHHHHHHCCCC
RSLKNGLRVTEQGEMIRFKLGLPAVAVESLGLYASAILEANLLPPPEPKAQWRTVMDELS
HHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
TISCQIYRDVVRGEKDFVPYFRAATPEQELSKLPLGSRPAKRNPNGGVESLRAIPWIFAW
HHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
MQNRLMLPAWLGAGASLRQAIEKGQKTVIEDMCKTWPFFSTRIGMLEMVFSKTDTWLSEH
HHCCEECHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
YDQHLVDPALWYLGESLREQLKQDIQTVLSLSHEDQLMSDLPWIAESIALRNVYTDPLNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LQVELLRRLRRNPDNPNPDVEQALMITITGVAAGMRNTG
HHHHHHHHHHCCCCCCCCCHHHHHHHEEHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100