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The map label for this gene is minC

Identifier: 15602308

GI number: 15602308

Start: 518936

End: 519613

Strand: Reverse

Name: minC

Synonym: PM0443

Alternate gene names: 15602308

Gene position: 519613-518936 (Counterclockwise)

Preceding gene: 15602310

Following gene: 15602301

Centisome position: 23.02

GC content: 38.94

Gene sequence:

>678_bases
ATGGCACAGGATATTGTAGCGTTTCGTACAGGGCAATTTTCATCAATTTTTCTTACTCTTCATAGCTCTAGCCTCAGCGT
GATTAAACGTGCCTTAAGCAAAAAAATCAAATCCTCCCCTTCAATTTTTCAACATATTGCTGTCATTCTCCAATTCACGC
CTGAACTTGAAAAAGTCAATCTACAAGCACTAAAAAGTCTCTGTGAAGAATTTAATATTCATATTATTGGAGTTTCAGAT
TGGACAAATCATCTGCAAAAAGAATTAATCATGACATCAGGCCTAGCCTTGTTGGGTAAGAGCGGTGAATTTACCGAGAT
TTTGCCAGAACCACGCTGTTTACCCGTCAAAATCATTCATCAACATGTTGCAAGCAAGCAAGTGATTTATGCCAAAAACA
GCGATCTGATTATTCATGGTAATGTAGAACCCGGCGCAGAAGTGGCTGCCGACGGTAATGTACATATTTATGGCAAGCTA
TTAGGACGTGCCATGGCTGGCGTGAATAACAATGTGGGTTCAATTTATACCCAATATCTTGATGCGGAATTCATTGCTGT
GAGTAGTCGCTTTTTATATAAAGACAACTTGCCTCATGAATACCAACATGAAGCCGTACGTATCTTTGCCGACAAAGACA
AATTGCGTTTTCACTTCTTGTTAGAAAAAGAAACCTAA

Upstream 100 bases:

>100_bases
ATAACATTGCTTTAACTTCCAATTCGAACAAAAAAGATTTGCCGATCCTAGCACAATTCTTTATGATTGGAACAAGTAAT
TTGTTTATTTGGATAGAGTT

Downstream 100 bases:

>100_bases
AGGATAAAAAAAATAGCGGAGAATACCTCCGCTATTTCTATCCGTGCATTATTGTGCTTTAGGCACAATCACTTCTTTTA
CTTCTTCTGTTTTTTCACTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MAQDIVAFRTGQFSSIFLTLHSSSLSVIKRALSKKIKSSPSIFQHIAVILQFTPELEKVNLQALKSLCEEFNIHIIGVSD
WTNHLQKELIMTSGLALLGKSGEFTEILPEPRCLPVKIIHQHVASKQVIYAKNSDLIIHGNVEPGAEVAADGNVHIYGKL
LGRAMAGVNNNVGSIYTQYLDAEFIAVSSRFLYKDNLPHEYQHEAVRIFADKDKLRFHFLLEKET

Sequences:

>Translated_225_residues
MAQDIVAFRTGQFSSIFLTLHSSSLSVIKRALSKKIKSSPSIFQHIAVILQFTPELEKVNLQALKSLCEEFNIHIIGVSD
WTNHLQKELIMTSGLALLGKSGEFTEILPEPRCLPVKIIHQHVASKQVIYAKNSDLIIHGNVEPGAEVAADGNVHIYGKL
LGRAMAGVNNNVGSIYTQYLDAEFIAVSSRFLYKDNLPHEYQHEAVRIFADKDKLRFHFLLEKET
>Mature_224_residues
AQDIVAFRTGQFSSIFLTLHSSSLSVIKRALSKKIKSSPSIFQHIAVILQFTPELEKVNLQALKSLCEEFNIHIIGVSDW
TNHLQKELIMTSGLALLGKSGEFTEILPEPRCLPVKIIHQHVASKQVIYAKNSDLIIHGNVEPGAEVAADGNVHIYGKLL
GRAMAGVNNNVGSIYTQYLDAEFIAVSSRFLYKDNLPHEYQHEAVRIFADKDKLRFHFLLEKET

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family

Homologues:

Organism=Escherichia coli, GI1787424, Length=221, Percent_Identity=29.8642533936652, Blast_Score=105, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINC_PASMU (P57845)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245380.1
- ProteinModelPortal:   P57845
- GeneID:   1243790
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0443
- NMPDR:   fig|272843.1.peg.443
- OMA:   IYARNRD
- ProtClustDB:   CLSK2517321
- BioCyc:   PMUL272843:PM0443-MONOMER
- HAMAP:   MF_00267
- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526
- Gene3D:   G3DSA:2.160.20.70
- TIGRFAMs:   TIGR01222

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N; SSF63848 MinC_C

EC number: NA

Molecular weight: Translated: 25210; Mature: 25079

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQDIVAFRTGQFSSIFLTLHSSSLSVIKRALSKKIKSSPSIFQHIAVILQFTPELEKVN
CCCCEEEEECCCCEEEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHCC
LQALKSLCEEFNIHIIGVSDWTNHLQKELIMTSGLALLGKSGEFTEILPEPRCLPVKIIH
HHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHCCHHEECCCCCCHHHCCCCCCCHHHHHH
QHVASKQVIYAKNSDLIIHGNVEPGAEVAADGNVHIYGKLLGRAMAGVNNNVGSIYTQYL
HHHCCCEEEEECCCCEEEECCCCCCCEEECCCCEEEHHHHHHHHHHCCCCCHHHHHHHHH
DAEFIAVSSRFLYKDNLPHEYQHEAVRIFADKDKLRFHFLLEKET
CHHEEEECCEEEECCCCCCHHHHCEEEEEECCCCEEEEEEEECCC
>Mature Secondary Structure 
AQDIVAFRTGQFSSIFLTLHSSSLSVIKRALSKKIKSSPSIFQHIAVILQFTPELEKVN
CCCEEEEECCCCEEEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHCC
LQALKSLCEEFNIHIIGVSDWTNHLQKELIMTSGLALLGKSGEFTEILPEPRCLPVKIIH
HHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHCCHHEECCCCCCHHHCCCCCCCHHHHHH
QHVASKQVIYAKNSDLIIHGNVEPGAEVAADGNVHIYGKLLGRAMAGVNNNVGSIYTQYL
HHHCCCEEEEECCCCEEEECCCCCCCEEECCCCEEEHHHHHHHHHHCCCCCHHHHHHHHH
DAEFIAVSSRFLYKDNLPHEYQHEAVRIFADKDKLRFHFLLEKET
CHHEEEECCEEEECCCCCCHHHHCEEEEEECCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100