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The map label for this gene is radA [H]

Identifier: 15602117

GI number: 15602117

Start: 282874

End: 284253

Strand: Direct

Name: radA [H]

Synonym: PM0252

Alternate gene names: 15602117

Gene position: 282874-284253 (Clockwise)

Preceding gene: 15602116

Following gene: 15602119

Centisome position: 12.53

GC content: 45.0

Gene sequence:

>1380_bases
ATGGCTAAGGCACCTAAAACAGCATATGTGTGTAATGATTGTGGCGCAGAGTTTTCTCGTTGGCAGGGACAATGTGCGGC
ATGTAAAGCTTGGAATACGATTAGTGAAGTGCGTTTAGTGTCATCTAGCAATAGCGCAAAAGGCGATCGTTTTAGTGGCT
ATGCTGGTGAAACGCGCGCGAAGATCCAAACCCTTGCTGAGATTTCATTACAGGAAACACCGCGTTTTTCCAGTGGTTTT
CACGAGTTGGATCGCGTTTTAGGGGGCGGTGTAGTACCGGGCAGTGCAATTTTAATTGGTGGTCATCCGGGCGCAGGCAA
AAGTACCTTATTGTTACAAGTGATGTGTGGTTTAGCACAAAATATGACCGCACTTTATGTGACAGGGGAGGAATCTTTGC
AACAGGTGGCAATGCGTGCAAAACGATTAGGCTTACCTACAGATAAATTAAACATGCTGTCTGAAACGTCAGTTGAACAA
ATTTGTCAGCTAGCGGATCAATTAAAACCGCAAATCATCGTGATTGACTCCATTCAAGTAATGCATTTAGCGGATATTCA
GTCTTCGCCAGGGAGTGTGGCACAAGTACGTGAATGTGCCTCTTTTTTAACGCGTTATGCGAAAACTCGCCAAGTAGCGA
TTATTATGGTGGGACATGTGACGAAAGACGGAACCTTAGCGGGTCCTAAAGTCCTTGAGCATTGTATCGACTGTTCAATT
TTGCTCGAAGGAGAGGCGGATTCTCGTTATCGTACTCTACGTAGCCATAAAAATCGTTTTGGTGCTGTGAATGAACTCGG
TGTGTTTGGCATGACAGAACAAGGGTTGCGTGAAGTGAAAAATCCATCAGCCATTTTTTTGAGTCGGGGCGAAGAGCAAA
CGCCGGGGAGTTCAGTGATGGTGATTTGGGAAGGAACACGCCCTTTATTAGTTGAAATTCAGGCGTTAGTTGACCATTCC
ATGTTAGCAAATCCGCGTCGTGTTGCTGTAGGGTTAGAACAAAACCGTTTAGCCTTGTTATTAGCAGTATTACATCGTCA
TGGTGGCTTACAAATGTCGGATCAAGATGTGTTTGTTAACGTAGTGGGCGGTGTTAAGGTCACGGAAACCAGTGCAGATT
TAGCATTGTTATTGGCATTAATTTCCAGTTTCCGTAATCGCCCATTGCCACAAGATTTAGTAGTTTTTGGTGAAGTGGGG
TTAGCGGGAGAAATTCGCCCAGTGCCAAGTGGGCAAGAGCGTATTGGTGAGGCAGCGAAACATGGCTTTAAGCGCGCAAT
TGTACCTTTCGCAAATAGACCGAAAAGTGCGGTGCCGAATATGGATGTTTTCACCGTTAAGAAATTGTCGGATGCCTTGG
CAATTTTAGAGAATTTCTAA

Upstream 100 bases:

>100_bases
TAATCGCCTTGTGTTAGACAAATTACTGGGCTTGTTGCAAACAGGTCATTATGTGAAACGTATGATCCATTTAACTTTTT
TAACGTTGAGTAATTAATTT

Downstream 100 bases:

>100_bases
GTGATGCGGTGGCTGTTATATTTATAAACAGCCACCGCAGCTACCACATCGCCAATCTTCTTGATTGACGGCTTGGTAAA
ATTGACGTAAGTAAGGTTCT

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MAKAPKTAYVCNDCGAEFSRWQGQCAACKAWNTISEVRLVSSSNSAKGDRFSGYAGETRAKIQTLAEISLQETPRFSSGF
HELDRVLGGGVVPGSAILIGGHPGAGKSTLLLQVMCGLAQNMTALYVTGEESLQQVAMRAKRLGLPTDKLNMLSETSVEQ
ICQLADQLKPQIIVIDSIQVMHLADIQSSPGSVAQVRECASFLTRYAKTRQVAIIMVGHVTKDGTLAGPKVLEHCIDCSI
LLEGEADSRYRTLRSHKNRFGAVNELGVFGMTEQGLREVKNPSAIFLSRGEEQTPGSSVMVIWEGTRPLLVEIQALVDHS
MLANPRRVAVGLEQNRLALLLAVLHRHGGLQMSDQDVFVNVVGGVKVTETSADLALLLALISSFRNRPLPQDLVVFGEVG
LAGEIRPVPSGQERIGEAAKHGFKRAIVPFANRPKSAVPNMDVFTVKKLSDALAILENF

Sequences:

>Translated_459_residues
MAKAPKTAYVCNDCGAEFSRWQGQCAACKAWNTISEVRLVSSSNSAKGDRFSGYAGETRAKIQTLAEISLQETPRFSSGF
HELDRVLGGGVVPGSAILIGGHPGAGKSTLLLQVMCGLAQNMTALYVTGEESLQQVAMRAKRLGLPTDKLNMLSETSVEQ
ICQLADQLKPQIIVIDSIQVMHLADIQSSPGSVAQVRECASFLTRYAKTRQVAIIMVGHVTKDGTLAGPKVLEHCIDCSI
LLEGEADSRYRTLRSHKNRFGAVNELGVFGMTEQGLREVKNPSAIFLSRGEEQTPGSSVMVIWEGTRPLLVEIQALVDHS
MLANPRRVAVGLEQNRLALLLAVLHRHGGLQMSDQDVFVNVVGGVKVTETSADLALLLALISSFRNRPLPQDLVVFGEVG
LAGEIRPVPSGQERIGEAAKHGFKRAIVPFANRPKSAVPNMDVFTVKKLSDALAILENF
>Mature_458_residues
AKAPKTAYVCNDCGAEFSRWQGQCAACKAWNTISEVRLVSSSNSAKGDRFSGYAGETRAKIQTLAEISLQETPRFSSGFH
ELDRVLGGGVVPGSAILIGGHPGAGKSTLLLQVMCGLAQNMTALYVTGEESLQQVAMRAKRLGLPTDKLNMLSETSVEQI
CQLADQLKPQIIVIDSIQVMHLADIQSSPGSVAQVRECASFLTRYAKTRQVAIIMVGHVTKDGTLAGPKVLEHCIDCSIL
LEGEADSRYRTLRSHKNRFGAVNELGVFGMTEQGLREVKNPSAIFLSRGEEQTPGSSVMVIWEGTRPLLVEIQALVDHSM
LANPRRVAVGLEQNRLALLLAVLHRHGGLQMSDQDVFVNVVGGVKVTETSADLALLLALISSFRNRPLPQDLVVFGEVGL
AGEIRPVPSGQERIGEAAKHGFKRAIVPFANRPKSAVPNMDVFTVKKLSDALAILENF

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=460, Percent_Identity=79.7826086956522, Blast_Score=772, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 49549; Mature: 49418

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: PS50162 RECA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKAPKTAYVCNDCGAEFSRWQGQCAACKAWNTISEVRLVSSSNSAKGDRFSGYAGETRA
CCCCCCCEEEECCCCCHHHHHCCCCHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCHHH
KIQTLAEISLQETPRFSSGFHELDRVLGGGVVPGSAILIGGHPGAGKSTLLLQVMCGLAQ
HHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHC
NMTALYVTGEESLQQVAMRAKRLGLPTDKLNMLSETSVEQICQLADQLKPQIIVIDSIQV
CCEEEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEE
MHLADIQSSPGSVAQVRECASFLTRYAKTRQVAIIMVGHVTKDGTLAGPKVLEHCIDCSI
EEEECCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCCCCHHHHHHHCCCEE
LLEGEADSRYRTLRSHKNRFGAVNELGVFGMTEQGLREVKNPSAIFLSRGEEQTPGSSVM
EEECCCCHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCEEE
VIWEGTRPLLVEIQALVDHSMLANPRRVAVGLEQNRLALLLAVLHRHGGLQMSDQDVFVN
EEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEE
VVGGVKVTETSADLALLLALISSFRNRPLPQDLVVFGEVGLAGEIRPVPSGQERIGEAAK
EECCEEEECCHHHHHHHHHHHHHHHCCCCCCHHEEEECCCCCCCCCCCCCCHHHHHHHHH
HGFKRAIVPFANRPKSAVPNMDVFTVKKLSDALAILENF
HCHHEEECCCCCCCCCCCCCCCEEHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKAPKTAYVCNDCGAEFSRWQGQCAACKAWNTISEVRLVSSSNSAKGDRFSGYAGETRA
CCCCCCEEEECCCCCHHHHHCCCCHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCHHH
KIQTLAEISLQETPRFSSGFHELDRVLGGGVVPGSAILIGGHPGAGKSTLLLQVMCGLAQ
HHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHC
NMTALYVTGEESLQQVAMRAKRLGLPTDKLNMLSETSVEQICQLADQLKPQIIVIDSIQV
CCEEEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEE
MHLADIQSSPGSVAQVRECASFLTRYAKTRQVAIIMVGHVTKDGTLAGPKVLEHCIDCSI
EEEECCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCCCCHHHHHHHCCCEE
LLEGEADSRYRTLRSHKNRFGAVNELGVFGMTEQGLREVKNPSAIFLSRGEEQTPGSSVM
EEECCCCHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCEEE
VIWEGTRPLLVEIQALVDHSMLANPRRVAVGLEQNRLALLLAVLHRHGGLQMSDQDVFVN
EEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEE
VVGGVKVTETSADLALLLALISSFRNRPLPQDLVVFGEVGLAGEIRPVPSGQERIGEAAK
EECCEEEECCHHHHHHHHHHHHHHHCCCCCCHHEEEECCCCCCCCCCCCCCHHHHHHHHH
HGFKRAIVPFANRPKSAVPNMDVFTVKKLSDALAILENF
HCHHEEECCCCCCCCCCCCCCCEEHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]