Click here to switch to the map view.

The map label for this gene is era [H]

Identifier: 15595005

GI number: 15595005

Start: 700052

End: 700924

Strand: Reverse

Name: era [H]

Synonym: BB0660

Alternate gene names: 15595005

Gene position: 700924-700052 (Counterclockwise)

Preceding gene: 15595009

Following gene: 15595004

Centisome position: 76.96

GC content: 26.35

Gene sequence:

>873_bases
ATGAAATCGGGATTTGCAGCAATACTTGGTAGACCATCAACTGGAAAATCTACCCTTTTAAATTCAATATGCGGACATAA
AATATCAATAATATCCCCTATTCCGCAAACAACTAGAAATAATATAAAAGGAATCTTTACGGACGACAGAGGACAAATTA
TTTTTATAGACACACCGGGATTTCATCTGAGTAAAAAAAAGTTTAATATTGCAATGATGAAAAATATCCACTCTTCAATA
GGAGAAGTTGAACTCATTTTATACATAATAGACATTCAAGACAAACCTGGAGAAGAAGAAAATAAAATGTTAGAAATAAT
TAAAAACTCTAAAATTAAATTTTTAGTAATACTTAATAAAATTGACCTTAAAAACACAAAAATAAAAGAAATAACGCAAT
TTCTAAAAGAAAAAGGAATAGAAGATAGTAATATAATTAAAATATCTGCTGAAAAAAAAATTAACACAGAAGAACTAAAA
AATAAAATTTATGAAAATTTTTCAGAAGGCCCACTTTATTATCCACAAGAATACTACACCGATCAAGAAATAAATTTTAG
AATTAGTGAAATAATAAGGGAAAAAGCTATTGAAAACCTAAAAGAAGAACTCCCCTATTCTTTGTATGTGGATATTGATA
CCTTAGAAAATAAAAAAGGAAGTCTTTTTATCAGAGCAAATATTTTTGTAGCCAATGAAAGTCAAAAAGGAATAATTGTA
GGAAAAAACGGAAAAGAAATAAAATCAATAGGAGAAAGGGCAAGAAAAACAATTGCAAAAATTTTTGAAACAAAATGCAA
CCTATTCTTACAGGTAAAACTTAAAAAAAATTGGAACAAAGAAGATAAGCTAATAAAAAGACTTATAAATTAA

Upstream 100 bases:

>100_bases
AAATTCCTCAAATTTTACTTAAAAATAAGTATTTAAAATACTATATAATTAATTATAATAAAAAATATATGAATATTACA
TATTTAAGGAATACTAAAAC

Downstream 100 bases:

>100_bases
CAAACATTAAACTGCATTTTTTTAAATTCTTGAAACTTGAAAAACAAAATGCTAAAATTTACCTAAATTTAAATTAGGAA
TAAAATGTGAAAACAGCACA

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MKSGFAAILGRPSTGKSTLLNSICGHKISIISPIPQTTRNNIKGIFTDDRGQIIFIDTPGFHLSKKKFNIAMMKNIHSSI
GEVELILYIIDIQDKPGEEENKMLEIIKNSKIKFLVILNKIDLKNTKIKEITQFLKEKGIEDSNIIKISAEKKINTEELK
NKIYENFSEGPLYYPQEYYTDQEINFRISEIIREKAIENLKEELPYSLYVDIDTLENKKGSLFIRANIFVANESQKGIIV
GKNGKEIKSIGERARKTIAKIFETKCNLFLQVKLKKNWNKEDKLIKRLIN

Sequences:

>Translated_290_residues
MKSGFAAILGRPSTGKSTLLNSICGHKISIISPIPQTTRNNIKGIFTDDRGQIIFIDTPGFHLSKKKFNIAMMKNIHSSI
GEVELILYIIDIQDKPGEEENKMLEIIKNSKIKFLVILNKIDLKNTKIKEITQFLKEKGIEDSNIIKISAEKKINTEELK
NKIYENFSEGPLYYPQEYYTDQEINFRISEIIREKAIENLKEELPYSLYVDIDTLENKKGSLFIRANIFVANESQKGIIV
GKNGKEIKSIGERARKTIAKIFETKCNLFLQVKLKKNWNKEDKLIKRLIN
>Mature_290_residues
MKSGFAAILGRPSTGKSTLLNSICGHKISIISPIPQTTRNNIKGIFTDDRGQIIFIDTPGFHLSKKKFNIAMMKNIHSSI
GEVELILYIIDIQDKPGEEENKMLEIIKNSKIKFLVILNKIDLKNTKIKEITQFLKEKGIEDSNIIKISAEKKINTEELK
NKIYENFSEGPLYYPQEYYTDQEINFRISEIIREKAIENLKEELPYSLYVDIDTLENKKGSLFIRANIFVANESQKGIIV
GKNGKEIKSIGERARKTIAKIFETKCNLFLQVKLKKNWNKEDKLIKRLIN

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=320, Percent_Identity=25.625, Blast_Score=86, Evalue=6e-17,
Organism=Escherichia coli, GI1788919, Length=289, Percent_Identity=37.3702422145329, Blast_Score=186, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 33355; Mature: 33355

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSGFAAILGRPSTGKSTLLNSICGHKISIISPIPQTTRNNIKGIFTDDRGQIIFIDTPG
CCCCCEEEEECCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEECCCCEEEEEECCC
FHLSKKKFNIAMMKNIHSSIGEVELILYIIDIQDKPGEEENKMLEIIKNSKIKFLVILNK
CEECCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEEEE
IDLKNTKIKEITQFLKEKGIEDSNIIKISAEKKINTEELKNKIYENFSEGPLYYPQEYYT
CCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCHHHCC
DQEINFRISEIIREKAIENLKEELPYSLYVDIDTLENKKGSLFIRANIFVANESQKGIIV
CCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCEEEEEEEEEECCCCCCEEE
GKNGKEIKSIGERARKTIAKIFETKCNLFLQVKLKKNWNKEDKLIKRLIN
CCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKSGFAAILGRPSTGKSTLLNSICGHKISIISPIPQTTRNNIKGIFTDDRGQIIFIDTPG
CCCCCEEEEECCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEECCCCEEEEEECCC
FHLSKKKFNIAMMKNIHSSIGEVELILYIIDIQDKPGEEENKMLEIIKNSKIKFLVILNK
CEECCCHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEEEE
IDLKNTKIKEITQFLKEKGIEDSNIIKISAEKKINTEELKNKIYENFSEGPLYYPQEYYT
CCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCHHHCC
DQEINFRISEIIREKAIENLKEELPYSLYVDIDTLENKKGSLFIRANIFVANESQKGIIV
CCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCEEEEEEEEEECCCCCCEEE
GKNGKEIKSIGERARKTIAKIFETKCNLFLQVKLKKNWNKEDKLIKRLIN
CCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA