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The map label for this gene is cdd [H]

Identifier: 15594963

GI number: 15594963

Start: 645137

End: 645601

Strand: Reverse

Name: cdd [H]

Synonym: BB0618

Alternate gene names: 15594963

Gene position: 645601-645137 (Counterclockwise)

Preceding gene: 15594965

Following gene: 15594961

Centisome position: 70.89

GC content: 27.74

Gene sequence:

>465_bases
TTGGAAAAACTAAAACAAGAAGATATAGATAAAGCATTTTATATGGCAGAAAAAGCACGAAATAATTCATATTCTCCATA
TTCAAAATTCAAAGTAGGTGCCTGCATTAAGACCAAAACAAACGATTTTTTTATTGGAACAAATGTTGAGAATGCAAGCT
TTGGAGCAACTTGTTGTGCAGAAAGAAGTGCGATTTTAAATATGATTGCAAAAATTGGCGTACAAGAAATAGATTTTTTA
TTACTTAATACAAGTCCTGAATGTATTCCGTGCGCTATATGCCTGCAAGTAATGGCAGAATTTTTTAATCAAGATACAAA
AATAATAATAACAGAATCTAAATCATTTAGTGAAAACAAAACACCAATAAAAATTTATACATTAAAAGATTTACTTAAAT
CTCCTTTTGATAAAAAAGAACTACGAAGAGTAACATACTCTGAGCTTGAAAAAAAATTAATTTAA

Upstream 100 bases:

>100_bases
TTCCGCAAAACAAGTTTTTAGCTTATTTTACATTGACTATATTACAATATTTCAATAAAATAAACCACAATGGCTAATAA
AATATAACAGGTGGGAAATT

Downstream 100 bases:

>100_bases
TTTAATATCTTTAGAGAAACCAAAGCACTTGCAAACTTATTTAATTTGTTGCTTTCAAGAGTATGAGCAGATAAATCAAA
TACATTTAAAATAAGCTTTT

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MEKLKQEDIDKAFYMAEKARNNSYSPYSKFKVGACIKTKTNDFFIGTNVENASFGATCCAERSAILNMIAKIGVQEIDFL
LLNTSPECIPCAICLQVMAEFFNQDTKIIITESKSFSENKTPIKIYTLKDLLKSPFDKKELRRVTYSELEKKLI

Sequences:

>Translated_154_residues
MEKLKQEDIDKAFYMAEKARNNSYSPYSKFKVGACIKTKTNDFFIGTNVENASFGATCCAERSAILNMIAKIGVQEIDFL
LLNTSPECIPCAICLQVMAEFFNQDTKIIITESKSFSENKTPIKIYTLKDLLKSPFDKKELRRVTYSELEKKLI
>Mature_154_residues
MEKLKQEDIDKAFYMAEKARNNSYSPYSKFKVGACIKTKTNDFFIGTNVENASFGATCCAERSAILNMIAKIGVQEIDFL
LLNTSPECIPCAICLQVMAEFFNQDTKIIITESKSFSENKTPIKIYTLKDLLKSPFDKKELRRVTYSELEKKLI

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=143, Percent_Identity=30.0699300699301, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17551074, Length=117, Percent_Identity=41.025641025641, Blast_Score=83, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17540514, Length=130, Percent_Identity=36.1538461538462, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323274, Length=129, Percent_Identity=34.1085271317829, Blast_Score=72, Evalue=4e-14,
Organism=Drosophila melanogaster, GI19920920, Length=143, Percent_Identity=32.8671328671329, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24582744, Length=109, Percent_Identity=33.9449541284404, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 17549; Mature: 17549

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLKQEDIDKAFYMAEKARNNSYSPYSKFKVGACIKTKTNDFFIGTNVENASFGATCCA
CCCCHHHHHHHHHHHHHHHCCCCCCCCHHEEECEEEEECCCCEEEECCCCCCCCCHHHHH
ERSAILNMIAKIGVQEIDFLLLNTSPECIPCAICLQVMAEFFNQDTKIIITESKSFSENK
HHHHHHHHHHHHCHHHHEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCC
TPIKIYTLKDLLKSPFDKKELRRVTYSELEKKLI
CCEEEEEHHHHHHCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEKLKQEDIDKAFYMAEKARNNSYSPYSKFKVGACIKTKTNDFFIGTNVENASFGATCCA
CCCCHHHHHHHHHHHHHHHCCCCCCCCHHEEECEEEEECCCCEEEECCCCCCCCCHHHHH
ERSAILNMIAKIGVQEIDFLLLNTSPECIPCAICLQVMAEFFNQDTKIIITESKSFSENK
HHHHHHHHHHHHCHHHHEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCC
TPIKIYTLKDLLKSPFDKKELRRVTYSELEKKLI
CCEEEEEHHHHHHCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]