| Definition | Borrelia burgdorferi B31 chromosome, complete genome. |
|---|---|
| Accession | NC_001318 |
| Length | 910,724 |
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The map label for this gene is dnaJ
Identifier: 15594862
GI number: 15594862
Start: 528104
End: 529198
Strand: Reverse
Name: dnaJ
Synonym: BB0517
Alternate gene names: 15594862
Gene position: 529198-528104 (Counterclockwise)
Preceding gene: 15594863
Following gene: 15594861
Centisome position: 58.11
GC content: 32.05
Gene sequence:
>1095_bases GTGAAAAAAGATTATTATGAAATTTTGGGGCTCTCAAAAGGAGCCTCAAAAGATGAGATAAAAAAAGCTTATAGAAAAAT AGCAATTAAATATCACCCAGACAGAAATCAAGGGAATGAAGAAGCCGCCTCTATCTTTAAAGAAGCCACTCAGGCTTACG AAATTTTAATAGATGACAATAAAAAAGCTAAATACGACAGATTTGGGCATTCCGCTTTTGAAGGAGGAGGATTTGAAGGA TTTTCAGGTGGATTTAGTGGATTTTCAGACATCTTTGAAGATTTTGGCGATATTTTTGATTCATTTTTCACTGGAAACAA AGGACAAGAAAGAAATAGAAAACACGCAAAAGGTGAAGACTTAGGATACAACATAGAAATATCTCTTGAAAATGCATACT TTGGGTACAAAAATAACATAAACATAACAAGACAAATGCTCTGTGATTCTTGTCTCGGGAAAAAATCCGAAAAAGGTACA AGTCCTTCGATATGTAACATGTGTAACGGCAGCGGAAGAGTAGTGCAAGGCGGAGGATTTTTCAGAGTTACAACAACATG TTCTAAATGTTACGGAGAAGGTAAAATAATATCAAACCCTTGTAAATCCTGTAAAGGAAAAGGAAGTCTTACAAAGCAAG AAACCATTCAATTAAACATTCCCCCAGGCATTGATAATAACCAACAAATAAAAATGAAAGGCAAGGGAAATGTTAATCCA GATAATCAAGAATATGGTGATCTTTATGTAAAAATATTGATAAGATCTCATAAAGTATTCAAAAGAAATGGTAAAGATCT CTATGCAATGCTTCCAATAAGCTTTACTCAAGCAGCGCTTGGAAAAGAAGTGAAAATAAAAACAATCGCTTCAAAAGAGA TTAAAATACACATTCCAAAAGGAATAAACAATGAAGAACAAATTTTAATTAAAAATGCAGGGATGCCAATTCTTCAAACC GAAAAGTTTGGAAATTTAATATTAATCACCAAAATAAAAACACCTAAAAATTTAAATTCTAATGCTATTAAACTTTTTGA AAACTTGGGCAAAGAATTAAAAGATGGTGATGAAATAGATTTACTCAAAGCATAA
Upstream 100 bases:
>100_bases AGCAAAATGCAAACAGCCAACAAGAAAATGGCCCACAAAGCAATACAAGCGAAGAGGGTAAAGAGGCTGATTATGAGGTT GTTGACGAGGATAAAAAATA
Downstream 100 bases:
>100_bases TATGTATATAACTCATGCCAATTCAATAATTGAAAGCATAAAAAATAACAAAGGATTTGAACTTTATATATCAAAAAAAA AGTCCAAAAACTAAAGAAAT
Product: chaperone protein DnaJ
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 364; Mature: 364
Protein sequence:
>364_residues MKKDYYEILGLSKGASKDEIKKAYRKIAIKYHPDRNQGNEEAASIFKEATQAYEILIDDNKKAKYDRFGHSAFEGGGFEG FSGGFSGFSDIFEDFGDIFDSFFTGNKGQERNRKHAKGEDLGYNIEISLENAYFGYKNNINITRQMLCDSCLGKKSEKGT SPSICNMCNGSGRVVQGGGFFRVTTTCSKCYGEGKIISNPCKSCKGKGSLTKQETIQLNIPPGIDNNQQIKMKGKGNVNP DNQEYGDLYVKILIRSHKVFKRNGKDLYAMLPISFTQAALGKEVKIKTIASKEIKIHIPKGINNEEQILIKNAGMPILQT EKFGNLILITKIKTPKNLNSNAIKLFENLGKELKDGDEIDLLKA
Sequences:
>Translated_364_residues MKKDYYEILGLSKGASKDEIKKAYRKIAIKYHPDRNQGNEEAASIFKEATQAYEILIDDNKKAKYDRFGHSAFEGGGFEG FSGGFSGFSDIFEDFGDIFDSFFTGNKGQERNRKHAKGEDLGYNIEISLENAYFGYKNNINITRQMLCDSCLGKKSEKGT SPSICNMCNGSGRVVQGGGFFRVTTTCSKCYGEGKIISNPCKSCKGKGSLTKQETIQLNIPPGIDNNQQIKMKGKGNVNP DNQEYGDLYVKILIRSHKVFKRNGKDLYAMLPISFTQAALGKEVKIKTIASKEIKIHIPKGINNEEQILIKNAGMPILQT EKFGNLILITKIKTPKNLNSNAIKLFENLGKELKDGDEIDLLKA >Mature_364_residues MKKDYYEILGLSKGASKDEIKKAYRKIAIKYHPDRNQGNEEAASIFKEATQAYEILIDDNKKAKYDRFGHSAFEGGGFEG FSGGFSGFSDIFEDFGDIFDSFFTGNKGQERNRKHAKGEDLGYNIEISLENAYFGYKNNINITRQMLCDSCLGKKSEKGT SPSICNMCNGSGRVVQGGGFFRVTTTCSKCYGEGKIISNPCKSCKGKGSLTKQETIQLNIPPGIDNNQQIKMKGKGNVNP DNQEYGDLYVKILIRSHKVFKRNGKDLYAMLPISFTQAALGKEVKIKTIASKEIKIHIPKGINNEEQILIKNAGMPILQT EKFGNLILITKIKTPKNLNSNAIKLFENLGKELKDGDEIDLLKA
Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon
COG id: COG0484
COG function: function code O; DnaJ-class molecular chaperone with C-terminal Zn finger domain
Gene ontology:
Cell location: Cytoplasm
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 J domain
Homologues:
Organism=Homo sapiens, GI205360838, Length=358, Percent_Identity=30.1675977653631, Blast_Score=182, Evalue=5e-46, Organism=Homo sapiens, GI205360840, Length=358, Percent_Identity=30.1675977653631, Blast_Score=182, Evalue=5e-46, Organism=Homo sapiens, GI4504511, Length=368, Percent_Identity=32.6086956521739, Blast_Score=174, Evalue=2e-43, Organism=Homo sapiens, GI194328758, Length=335, Percent_Identity=33.134328358209, Blast_Score=156, Evalue=4e-38, Organism=Homo sapiens, GI194328760, Length=335, Percent_Identity=32.8358208955224, Blast_Score=155, Evalue=4e-38, Organism=Homo sapiens, GI5031741, Length=356, Percent_Identity=30.3370786516854, Blast_Score=151, Evalue=1e-36, Organism=Homo sapiens, GI7706495, Length=337, Percent_Identity=29.080118694362, Blast_Score=130, Evalue=3e-30, Organism=Homo sapiens, GI194328762, Length=292, Percent_Identity=30.1369863013699, Blast_Score=115, Evalue=5e-26, Organism=Homo sapiens, GI5453690, Length=368, Percent_Identity=25.5434782608696, Blast_Score=100, Evalue=3e-21, Organism=Homo sapiens, GI201862587, Length=402, Percent_Identity=25.8706467661692, Blast_Score=100, Evalue=4e-21, Organism=Homo sapiens, GI201862518, Length=374, Percent_Identity=25.9358288770053, Blast_Score=100, Evalue=4e-21, Organism=Homo sapiens, GI56549115, Length=374, Percent_Identity=25.9358288770053, Blast_Score=99, Evalue=4e-21, Organism=Homo sapiens, GI39204547, Length=365, Percent_Identity=23.013698630137, Blast_Score=94, Evalue=2e-19, Organism=Homo sapiens, GI6631085, Length=384, Percent_Identity=25, Blast_Score=94, Evalue=2e-19, Organism=Homo sapiens, GI47777312, Length=110, Percent_Identity=46.3636363636364, Blast_Score=89, Evalue=6e-18, Organism=Homo sapiens, GI9558755, Length=100, Percent_Identity=47, Blast_Score=88, Evalue=1e-17, Organism=Homo sapiens, GI27151736, Length=105, Percent_Identity=44.7619047619048, Blast_Score=86, Evalue=6e-17, Organism=Homo sapiens, GI21553335, Length=75, Percent_Identity=53.3333333333333, Blast_Score=85, Evalue=9e-17, Organism=Homo sapiens, GI88501736, Length=105, Percent_Identity=44.7619047619048, Blast_Score=85, Evalue=1e-16, Organism=Homo sapiens, GI194306642, Length=107, Percent_Identity=43.9252336448598, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI194306640, Length=107, Percent_Identity=43.9252336448598, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI23503241, Length=106, Percent_Identity=44.3396226415094, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI45504382, Length=64, Percent_Identity=54.6875, Blast_Score=78, Evalue=1e-14, Organism=Homo sapiens, GI17388799, Length=66, Percent_Identity=53.030303030303, Blast_Score=78, Evalue=1e-14, Organism=Homo sapiens, GI4885495, Length=66, Percent_Identity=53.030303030303, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI29126218, Length=64, Percent_Identity=54.6875, Blast_Score=76, Evalue=6e-14, Organism=Homo sapiens, GI24308127, Length=83, Percent_Identity=40.9638554216867, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI68077168, Length=77, Percent_Identity=48.0519480519481, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI68077166, Length=77, Percent_Identity=48.0519480519481, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI22749377, Length=110, Percent_Identity=34.5454545454545, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI72534740, Length=107, Percent_Identity=37.3831775700935, Blast_Score=65, Evalue=8e-11, Organism=Escherichia coli, GI1786197, Length=349, Percent_Identity=40.6876790830946, Blast_Score=279, Evalue=2e-76, Organism=Escherichia coli, GI1787235, Length=291, Percent_Identity=27.8350515463918, Blast_Score=98, Evalue=9e-22, Organism=Caenorhabditis elegans, GI17553098, Length=365, Percent_Identity=31.2328767123288, Blast_Score=156, Evalue=2e-38, Organism=Caenorhabditis elegans, GI17553096, Length=365, Percent_Identity=31.2328767123288, Blast_Score=156, Evalue=2e-38, Organism=Caenorhabditis elegans, GI17507263, Length=354, Percent_Identity=30.5084745762712, Blast_Score=144, Evalue=9e-35, Organism=Caenorhabditis elegans, GI212645553, Length=336, Percent_Identity=30.3571428571429, Blast_Score=114, Evalue=9e-26, Organism=Caenorhabditis elegans, GI17534355, Length=191, Percent_Identity=36.6492146596859, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI17563890, Length=230, Percent_Identity=26.0869565217391, Blast_Score=81, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17554644, Length=97, Percent_Identity=43.298969072165, Blast_Score=78, Evalue=8e-15, Organism=Caenorhabditis elegans, GI115532378, Length=84, Percent_Identity=44.047619047619, Blast_Score=76, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17538236, Length=126, Percent_Identity=38.0952380952381, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17568643, Length=69, Percent_Identity=46.3768115942029, Blast_Score=69, Evalue=4e-12, Organism=Caenorhabditis elegans, GI115532476, Length=68, Percent_Identity=47.0588235294118, Blast_Score=68, Evalue=7e-12, Organism=Caenorhabditis elegans, GI86563276, Length=110, Percent_Identity=41.8181818181818, Blast_Score=66, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6324265, Length=341, Percent_Identity=37.2434017595308, Blast_Score=186, Evalue=4e-48, Organism=Saccharomyces cerevisiae, GI6323870, Length=359, Percent_Identity=30.9192200557103, Blast_Score=140, Evalue=3e-34, Organism=Saccharomyces cerevisiae, GI6323119, Length=382, Percent_Identity=30.1047120418848, Blast_Score=139, Evalue=8e-34, Organism=Saccharomyces cerevisiae, GI6321094, Length=395, Percent_Identity=30.126582278481, Blast_Score=114, Evalue=2e-26, Organism=Saccharomyces cerevisiae, GI6324252, Length=294, Percent_Identity=27.2108843537415, Blast_Score=105, Evalue=1e-23, Organism=Saccharomyces cerevisiae, GI6322194, Length=101, Percent_Identity=44.5544554455446, Blast_Score=80, Evalue=7e-16, Organism=Saccharomyces cerevisiae, GI6323813, Length=123, Percent_Identity=39.8373983739837, Blast_Score=71, Evalue=3e-13, Organism=Saccharomyces cerevisiae, GI6320888, Length=110, Percent_Identity=37.2727272727273, Blast_Score=69, Evalue=1e-12, Organism=Saccharomyces cerevisiae, GI6324321, Length=67, Percent_Identity=47.7611940298507, Blast_Score=67, Evalue=4e-12, Organism=Saccharomyces cerevisiae, GI6324103, Length=67, Percent_Identity=52.2388059701493, Blast_Score=66, Evalue=7e-12, Organism=Saccharomyces cerevisiae, GI6322388, Length=70, Percent_Identity=45.7142857142857, Blast_Score=63, Evalue=8e-11, Organism=Drosophila melanogaster, GI45552813, Length=367, Percent_Identity=28.6103542234332, Blast_Score=162, Evalue=2e-40, Organism=Drosophila melanogaster, GI45549272, Length=367, Percent_Identity=28.6103542234332, Blast_Score=162, Evalue=3e-40, Organism=Drosophila melanogaster, GI45552811, Length=367, Percent_Identity=28.6103542234332, Blast_Score=162, Evalue=3e-40, Organism=Drosophila melanogaster, GI24646562, Length=367, Percent_Identity=30.2452316076294, Blast_Score=158, Evalue=4e-39, Organism=Drosophila melanogaster, GI24646560, Length=367, Percent_Identity=30.2452316076294, Blast_Score=158, Evalue=4e-39, Organism=Drosophila melanogaster, GI24646558, Length=367, Percent_Identity=30.2452316076294, Blast_Score=158, Evalue=4e-39, Organism=Drosophila melanogaster, GI24646556, Length=367, Percent_Identity=30.2452316076294, Blast_Score=158, Evalue=4e-39, Organism=Drosophila melanogaster, GI21357547, Length=367, Percent_Identity=30.2452316076294, Blast_Score=158, Evalue=4e-39, Organism=Drosophila melanogaster, GI20129487, Length=349, Percent_Identity=30.6590257879656, Blast_Score=137, Evalue=1e-32, Organism=Drosophila melanogaster, GI24584014, Length=349, Percent_Identity=30.6590257879656, Blast_Score=137, Evalue=1e-32, Organism=Drosophila melanogaster, GI28574949, Length=355, Percent_Identity=25.0704225352113, Blast_Score=118, Evalue=8e-27, Organism=Drosophila melanogaster, GI85726398, Length=373, Percent_Identity=26.5415549597855, Blast_Score=106, Evalue=2e-23, Organism=Drosophila melanogaster, GI19920464, Length=338, Percent_Identity=26.3313609467456, Blast_Score=102, Evalue=5e-22, Organism=Drosophila melanogaster, GI24658562, Length=366, Percent_Identity=27.3224043715847, Blast_Score=99, Evalue=4e-21, Organism=Drosophila melanogaster, GI24658555, Length=366, Percent_Identity=27.3224043715847, Blast_Score=99, Evalue=4e-21, Organism=Drosophila melanogaster, GI18858081, Length=403, Percent_Identity=25.0620347394541, Blast_Score=78, Evalue=8e-15, Organism=Drosophila melanogaster, GI24668523, Length=64, Percent_Identity=56.25, Blast_Score=78, Evalue=9e-15, Organism=Drosophila melanogaster, GI17737735, Length=64, Percent_Identity=56.25, Blast_Score=78, Evalue=9e-15, Organism=Drosophila melanogaster, GI28574723, Length=64, Percent_Identity=56.25, Blast_Score=78, Evalue=1e-14, Organism=Drosophila melanogaster, GI24654066, Length=67, Percent_Identity=50.7462686567164, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24654070, Length=67, Percent_Identity=50.7462686567164, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24654068, Length=67, Percent_Identity=50.7462686567164, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24654072, Length=67, Percent_Identity=50.7462686567164, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI161077138, Length=64, Percent_Identity=51.5625, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24668492, Length=69, Percent_Identity=44.9275362318841, Blast_Score=72, Evalue=9e-13, Organism=Drosophila melanogaster, GI24584630, Length=70, Percent_Identity=51.4285714285714, Blast_Score=69, Evalue=5e-12, Organism=Drosophila melanogaster, GI17648033, Length=70, Percent_Identity=51.4285714285714, Blast_Score=69, Evalue=5e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): DNAJ_BORBU (P28616)
Other databases:
- EMBL: M97914 - EMBL: M96847 - EMBL: AE000783 - PIR: D70164 - RefSeq: NP_212651.1 - ProteinModelPortal: P28616 - EnsemblBacteria: EBBORT00000008411 - GeneID: 1195363 - GenomeReviews: AE000783_GR - KEGG: bbu:BB0517 - NMPDR: fig|224326.1.peg.901 - TIGR: BB_0517 - GeneTree: EBGT00050000007046 - HOGENOM: HBG635315 - OMA: GTENDEQ - PhylomeDB: P28616 - ProtClustDB: PRK14285 - BioCyc: BBUR224326:BB_0517-MONOMER - GO: GO:0005737 - HAMAP: MF_01152 - InterPro: IPR012724 - InterPro: IPR002939 - InterPro: IPR001623 - InterPro: IPR018253 - InterPro: IPR008971 - InterPro: IPR015609 - InterPro: IPR003095 - InterPro: IPR001305 - Gene3D: G3DSA:1.10.287.110 - Gene3D: G3DSA:2.10.230.10 - PANTHER: PTHR11821 - PRINTS: PR00625 - SMART: SM00271 - TIGRFAMs: TIGR02349
Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG; SSF46565 DnaJ_N; SSF49493 HSP40_DnaJ_pep; SSF57938 HSP_DnaJ_cys-rich
EC number: NA
Molecular weight: Translated: 40499; Mature: 40499
Theoretical pI: Translated: 9.50; Mature: 9.50
Prosite motif: PS00636 DNAJ_1; PS50076 DNAJ_2; PS51188 ZF_CR; PS00387 PPASE ; PS00637 DNAJ_CXXCXGXG
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.2 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 2.2 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 3.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKKDYYEILGLSKGASKDEIKKAYRKIAIKYHPDRNQGNEEAASIFKEATQAYEILIDDN CCCHHHHHHCCCCCCCHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHEEEEEECC KKAKYDRFGHSAFEGGGFEGFSGGFSGFSDIFEDFGDIFDSFFTGNKGQERNRKHAKGED CCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCC LGYNIEISLENAYFGYKNNINITRQMLCDSCLGKKSEKGTSPSICNMCNGSGRVVQGGGF CCEEEEEEEECEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCEEECCCE FRVTTTCSKCYGEGKIISNPCKSCKGKGSLTKQETIQLNIPPGIDNNQQIKMKGKGNVNP EEEEEEHHHHCCCCCEECCHHHHCCCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCC DNQEYGDLYVKILIRSHKVFKRNGKDLYAMLPISFTQAALGKEVKIKTIASKEIKIHIPK CCCHHHHHEEEHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCEEEEEEECCEEEEEECC GINNEEQILIKNAGMPILQTEKFGNLILITKIKTPKNLNSNAIKLFENLGKELKDGDEID CCCCCCEEEEEECCCCEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEE LLKA EECC >Mature Secondary Structure MKKDYYEILGLSKGASKDEIKKAYRKIAIKYHPDRNQGNEEAASIFKEATQAYEILIDDN CCCHHHHHHCCCCCCCHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHEEEEEECC KKAKYDRFGHSAFEGGGFEGFSGGFSGFSDIFEDFGDIFDSFFTGNKGQERNRKHAKGED CCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCC LGYNIEISLENAYFGYKNNINITRQMLCDSCLGKKSEKGTSPSICNMCNGSGRVVQGGGF CCEEEEEEEECEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCEEECCCE FRVTTTCSKCYGEGKIISNPCKSCKGKGSLTKQETIQLNIPPGIDNNQQIKMKGKGNVNP EEEEEEHHHHCCCCCEECCHHHHCCCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCC DNQEYGDLYVKILIRSHKVFKRNGKDLYAMLPISFTQAALGKEVKIKTIASKEIKIHIPK CCCHHHHHEEEHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCEEEEEEECCEEEEEECC GINNEEQILIKNAGMPILQTEKFGNLILITKIKTPKNLNSNAIKLFENLGKELKDGDEID CCCCCCEEEEEECCCCEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEE LLKA EECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 1383161; 8459764; 9403685