Click here to switch to the map view.

The map label for this gene is engA [H]

Identifier: 15594853

GI number: 15594853

Start: 513226

End: 514527

Strand: Direct

Name: engA [H]

Synonym: BB0508

Alternate gene names: 15594853

Gene position: 513226-514527 (Clockwise)

Preceding gene: 15594851

Following gene: 15594854

Centisome position: 56.35

GC content: 28.42

Gene sequence:

>1302_bases
TTGCTTAGTTATAAAAAGGTTCTTATTGTTGGTAGACCAAATGTTGGTAAATCTGCTTTATTTAATCGAATTTTAGATAC
AAAAAGAAGTATTACTGAGAGTACTTACGGTGTTACTAGAGATTTAGTTGAAGAAGTTTGTAAGGTTGATTCTTTTAAGT
TTAAATTAATCGATACTGGTGGGTTTACTATCTTGAAAGATGAGATTAGCAAAATTGTTGTGCAAAAGGTTTTAAGCTCT
TTAGAAAAAGTTGATTTAATTTTATTGGTTTTAGATATTAATGAAATTTTACTTGAAGATTATCAGATTATTGAAAGACT
GAGAAAATATAGTAGTAAGGTGGTTTTGGTTTTAAACAAAGTAGATACTAAGGATAAGGAATGTTTAGCTCACGAATTTC
ATAATTTAGGATTCAAGCGCTATTTTCTGGTTAGTGCAGCCCATTGTCGAGGCATTACTAAGCTTAGAGATTTTTTAAAA
GTAGAAGTTGGTGAAGTTGGCATTGAGAGTGGCGCTGATATTAAGGTTGGGATTATAGGCAAGCCTAATTCAGGCAAATC
TACCCTTATTAATTATTTATCTGGAAATGAAATTGCAATTGTTTCTGATCAACCTGGTACTACTAGAGATTTTATTAAAA
CTAAGTTTACTAGAAATGGGAAAGTTTTTGAGGTTGTTGATACAGCTGGGATAAGGCGAAGGGCAAGAGTAAATGAAATT
GTTGAATATTATTCTGTTAATAGGGCCCTAAAAGTAATTGACATGGTAGATATTGTGTTTTTATTGATTGATGTTCAAGA
AAAATTGACTTCTCAGGATAAAAAAATTGCTCATTATGTTACTAAAAAGGGGAAAGGAATTGTTATTGTGTTTAGCAAAT
GGGATCTTGTGGATGAGTCTAAAGGTTATTTTGAAGCCTTAAAGAGCCATGTGAAGTTTTTTTTTCCTATTTTAAATTTT
GCTCCTATATTTAGAATTTCTGTTCATAAAAGGATAGGTTTAGATTCTCTTTTTAAAGAATCTTTTAAGTTAAAAGATCA
GCTTGAGCTTAAAACCAGTACTCCAGATCTAAATAAAATGTTAAATTTATGGATCAAAGATTATCATTTAAATATTTCTC
ATAAAATCAAATATATTACACAAGTTAGTACTAATCCTGTTAAGTTTATTCTTTTTGCAAATAAAATAAAGAATTTTCCA
AATTCTTACTATAATTATTTAGTAAATAATTTGCGTAAAATTGGATATAAAAATATTCCAATTTTAGTAGAATTAAAGGA
AAAAATAAGAGATTTAAAGTGA

Upstream 100 bases:

>100_bases
TTTTTTCTTTTCAATATAAACACTCATGTGTAATTGGCATAAATACTAATATTTGCTATTATAATGGAAATATCGGAATA
AATAAAGAGGTGTATTTGCT

Downstream 100 bases:

>100_bases
GATATATATTTTTATTCTTAATATTTAAGAGTCTAAATCTTTTTGCGCTTGAGAGTTTTTTTTATGATTTTGATGTAAGG
ACTAAATATTTAAAATATTT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MLSYKKVLIVGRPNVGKSALFNRILDTKRSITESTYGVTRDLVEEVCKVDSFKFKLIDTGGFTILKDEISKIVVQKVLSS
LEKVDLILLVLDINEILLEDYQIIERLRKYSSKVVLVLNKVDTKDKECLAHEFHNLGFKRYFLVSAAHCRGITKLRDFLK
VEVGEVGIESGADIKVGIIGKPNSGKSTLINYLSGNEIAIVSDQPGTTRDFIKTKFTRNGKVFEVVDTAGIRRRARVNEI
VEYYSVNRALKVIDMVDIVFLLIDVQEKLTSQDKKIAHYVTKKGKGIVIVFSKWDLVDESKGYFEALKSHVKFFFPILNF
APIFRISVHKRIGLDSLFKESFKLKDQLELKTSTPDLNKMLNLWIKDYHLNISHKIKYITQVSTNPVKFILFANKIKNFP
NSYYNYLVNNLRKIGYKNIPILVELKEKIRDLK

Sequences:

>Translated_433_residues
MLSYKKVLIVGRPNVGKSALFNRILDTKRSITESTYGVTRDLVEEVCKVDSFKFKLIDTGGFTILKDEISKIVVQKVLSS
LEKVDLILLVLDINEILLEDYQIIERLRKYSSKVVLVLNKVDTKDKECLAHEFHNLGFKRYFLVSAAHCRGITKLRDFLK
VEVGEVGIESGADIKVGIIGKPNSGKSTLINYLSGNEIAIVSDQPGTTRDFIKTKFTRNGKVFEVVDTAGIRRRARVNEI
VEYYSVNRALKVIDMVDIVFLLIDVQEKLTSQDKKIAHYVTKKGKGIVIVFSKWDLVDESKGYFEALKSHVKFFFPILNF
APIFRISVHKRIGLDSLFKESFKLKDQLELKTSTPDLNKMLNLWIKDYHLNISHKIKYITQVSTNPVKFILFANKIKNFP
NSYYNYLVNNLRKIGYKNIPILVELKEKIRDLK
>Mature_433_residues
MLSYKKVLIVGRPNVGKSALFNRILDTKRSITESTYGVTRDLVEEVCKVDSFKFKLIDTGGFTILKDEISKIVVQKVLSS
LEKVDLILLVLDINEILLEDYQIIERLRKYSSKVVLVLNKVDTKDKECLAHEFHNLGFKRYFLVSAAHCRGITKLRDFLK
VEVGEVGIESGADIKVGIIGKPNSGKSTLINYLSGNEIAIVSDQPGTTRDFIKTKFTRNGKVFEVVDTAGIRRRARVNEI
VEYYSVNRALKVIDMVDIVFLLIDVQEKLTSQDKKIAHYVTKKGKGIVIVFSKWDLVDESKGYFEALKSHVKFFFPILNF
APIFRISVHKRIGLDSLFKESFKLKDQLELKTSTPDLNKMLNLWIKDYHLNISHKIKYITQVSTNPVKFILFANKIKNFP
NSYYNYLVNNLRKIGYKNIPILVELKEKIRDLK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=457, Percent_Identity=30.4157549234136, Blast_Score=224, Evalue=7e-60,
Organism=Escherichia coli, GI2367268, Length=91, Percent_Identity=40.6593406593407, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788919, Length=139, Percent_Identity=30.9352517985612, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17507259, Length=120, Percent_Identity=38.3333333333333, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323665, Length=259, Percent_Identity=31.2741312741313, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI45550813, Length=174, Percent_Identity=30.4597701149425, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49725; Mature: 49725

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: PS00134 TRYPSIN_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSYKKVLIVGRPNVGKSALFNRILDTKRSITESTYGVTRDLVEEVCKVDSFKFKLIDTG
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
GFTILKDEISKIVVQKVLSSLEKVDLILLVLDINEILLEDYQIIERLRKYSSKVVLVLNK
CCEEEHHHHHHHHHHHHHHHHHHHEEEEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEEC
VDTKDKECLAHEFHNLGFKRYFLVSAAHCRGITKLRDFLKVEVGEVGIESGADIKVGIIG
CCCCHHHHHHHHHHHCCCHHHHEEEHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEE
KPNSGKSTLINYLSGNEIAIVSDQPGTTRDFIKTKFTRNGKVFEVVDTAGIRRRARVNEI
CCCCCHHHHHHEECCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHH
VEYYSVNRALKVIDMVDIVFLLIDVQEKLTSQDKKIAHYVTKKGKGIVIVFSKWDLVDES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEECCCCCCCC
KGYFEALKSHVKFFFPILNFAPIFRISVHKRIGLDSLFKESFKLKDQLELKTSTPDLNKM
CHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCHHHHHHHHHCCCHHEEEECCCCCHHHH
LNLWIKDYHLNISHKIKYITQVSTNPVKFILFANKIKNFPNSYYNYLVNNLRKIGYKNIP
HHHHHHHEEECHHHHEEEEEEECCCCEEEEEEHHHHCCCCHHHHHHHHHHHHHCCCCCCC
ILVELKEKIRDLK
EEEEEHHHHCCCC
>Mature Secondary Structure
MLSYKKVLIVGRPNVGKSALFNRILDTKRSITESTYGVTRDLVEEVCKVDSFKFKLIDTG
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
GFTILKDEISKIVVQKVLSSLEKVDLILLVLDINEILLEDYQIIERLRKYSSKVVLVLNK
CCEEEHHHHHHHHHHHHHHHHHHHEEEEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEEC
VDTKDKECLAHEFHNLGFKRYFLVSAAHCRGITKLRDFLKVEVGEVGIESGADIKVGIIG
CCCCHHHHHHHHHHHCCCHHHHEEEHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEE
KPNSGKSTLINYLSGNEIAIVSDQPGTTRDFIKTKFTRNGKVFEVVDTAGIRRRARVNEI
CCCCCHHHHHHEECCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHH
VEYYSVNRALKVIDMVDIVFLLIDVQEKLTSQDKKIAHYVTKKGKGIVIVFSKWDLVDES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEECCCCCCCC
KGYFEALKSHVKFFFPILNFAPIFRISVHKRIGLDSLFKESFKLKDQLELKTSTPDLNKM
CHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCHHHHHHHHHCCCHHEEEECCCCCHHHH
LNLWIKDYHLNISHKIKYITQVSTNPVKFILFANKIKNFPNSYYNYLVNNLRKIGYKNIP
HHHHHHHEEECHHHHEEEEEEECCCCEEEEEEHHHHCCCCHHHHHHHHHHHHHCCCCCCC
ILVELKEKIRDLK
EEEEEHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA