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The map label for this gene is lspA [H]

Identifier: 15594814

GI number: 15594814

Start: 488983

End: 489495

Strand: Direct

Name: lspA [H]

Synonym: BB0469

Alternate gene names: 15594814

Gene position: 488983-489495 (Clockwise)

Preceding gene: 15594813

Following gene: 15594815

Centisome position: 53.69

GC content: 23.98

Gene sequence:

>513_bases
ATGAGCGCTAAAAGTAAGCAATATTTCAATATTTTTGTATTTATTATTAGTTTGATTTTTTTTGATCAACTTTCTAAGTA
TTTGGTTGCAAAGTATGTTAAATTAGGTTCAATATATTTTTCCTTTTTTGATGATTTTTTTAGGATAATACATGTAAGAA
ACACAGGTATTTTATTTTCTATGGGCTCTAATATCCATTATAGCTTGAAAAAAATTTTTTTTCTTGCAATGCCTATTTTC
ATTTTAATATTTGTTTTTTATCTTTCTTTGAAAGAAAGAAATTGTATTGCCAGAATTTCACTTTTATTAATTTTTTCAGG
AGGAGTAGGAAATGTTATTGATAGATTGTTTAGACCTTCTGGAGTTGTAGATTTTTTAGATTTGAAATTTTATGGAATTT
TTGGACTTGATAGATGGCCTACTTTTAATTTTGCAGATAGCTATGTTGTTATAGGTATGATTTTATTTTTGGTTTATGAT
TTTTTTATAAAAAGAAAAGTGCTTAATAAATGA

Upstream 100 bases:

>100_bases
GAAACTTTTGGTTTAATTAAATTAATGGAAGATTTCAAAATTCAAGAAGATTTAGAGGTTAAATTTATTTGTAAAAATAC
TAATTTATAAGGATTTTTGT

Downstream 100 bases:

>100_bases
AGATTTTGAGTTTTATTTTATGTATGTTAATGAACTTATCATTAATGTTTCTAGTTTTCTTTTTAGAGTTTTTTTTAGTT
GTTAAATTTAGCATTATTGT

Product: signal peptidase II

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MSAKSKQYFNIFVFIISLIFFDQLSKYLVAKYVKLGSIYFSFFDDFFRIIHVRNTGILFSMGSNIHYSLKKIFFLAMPIF
ILIFVFYLSLKERNCIARISLLLIFSGGVGNVIDRLFRPSGVVDFLDLKFYGIFGLDRWPTFNFADSYVVIGMILFLVYD
FFIKRKVLNK

Sequences:

>Translated_170_residues
MSAKSKQYFNIFVFIISLIFFDQLSKYLVAKYVKLGSIYFSFFDDFFRIIHVRNTGILFSMGSNIHYSLKKIFFLAMPIF
ILIFVFYLSLKERNCIARISLLLIFSGGVGNVIDRLFRPSGVVDFLDLKFYGIFGLDRWPTFNFADSYVVIGMILFLVYD
FFIKRKVLNK
>Mature_169_residues
SAKSKQYFNIFVFIISLIFFDQLSKYLVAKYVKLGSIYFSFFDDFFRIIHVRNTGILFSMGSNIHYSLKKIFFLAMPIFI
LIFVFYLSLKERNCIARISLLLIFSGGVGNVIDRLFRPSGVVDFLDLKFYGIFGLDRWPTFNFADSYVVIGMILFLVYDF
FIKRKVLNK

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 19976; Mature: 19845

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKSKQYFNIFVFIISLIFFDQLSKYLVAKYVKLGSIYFSFFDDFFRIIHVRNTGILFS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
MGSNIHYSLKKIFFLAMPIFILIFVFYLSLKERNCIARISLLLIFSGGVGNVIDRLFRPS
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHCCC
GVVDFLDLKFYGIFGLDRWPTFNFADSYVVIGMILFLVYDFFIKRKVLNK
CCHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SAKSKQYFNIFVFIISLIFFDQLSKYLVAKYVKLGSIYFSFFDDFFRIIHVRNTGILFS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
MGSNIHYSLKKIFFLAMPIFILIFVFYLSLKERNCIARISLLLIFSGGVGNVIDRLFRPS
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHCCC
GVVDFLDLKFYGIFGLDRWPTFNFADSYVVIGMILFLVYDFFIKRKVLNK
CCHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA