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The map label for this gene is yggV [C]

Identifier: 15594592

GI number: 15594592

Start: 252434

End: 253039

Strand: Direct

Name: yggV [C]

Synonym: BB0247

Alternate gene names: 15594592

Gene position: 252434-253039 (Clockwise)

Preceding gene: 15594588

Following gene: 15594593

Centisome position: 27.72

GC content: 23.6

Gene sequence:

>606_bases
ATGAAAACACTATTTTTTGCAACAACAAATGAAAATAAAATAAATGAAGTAAAAAATATATTAGATATACCTAATTTAAA
CTTAATAGTCCCTCAAAATTTTAACATAAAAGAAACAGGAAAAACATTTAAAGAAAACTCTTTACTTAAAGCAAAAGCAC
TGTTTGAAATTTTAAATAACAATCAAAATGTTTTCGGAGAAGATTCTGGGCTGTGCATTGAGGCACTAAACTTGGAACCT
GGAATTTACTCTAAAAGATATGACACTTATAAGCTATGTAAAAAATTAAGCACTAATGAAAAAAATCAACTAATTTTGGA
CTTAATGAAAAATGAAAAAAACAGAAAAGCATATTTTATATGCAACATAAGCTATATATCAAAAAATGGGCAAATATTAA
ATTTTGAAGGAATTATTAAGGGAAAAATTGCCTTAAGTTTAAATGACAAGAAAAACTATGGATTTGGGTATGATTCAATA
TTTTTAACTAAAAATAATAAAAAGCTTAGTGATCTAACACTTGAAGAAAAAAACAAAATATCCCACAGAGGAATAGCATT
TTTAAAATTTAAAAAATTTTTACTAAAATCTTTATTCAATAGTTAA

Upstream 100 bases:

>100_bases
GGTACAAAAATACTTAATAAGTACACAAAATTAAAGAGAATAATACTTAAAACCAATATAATTATACAATTAAACTCATA
AATACTTTATTATTATATAG

Downstream 100 bases:

>100_bases
ACTTAAAGGCTTTTTATATATAAAGTTTAGACTTTATTGTAAAATAAAAAGCACAATGTTTATAAAATTTCAACTTATTA
TTTCTTTTCAAACAATAAAA

Product: deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MKTLFFATTNENKINEVKNILDIPNLNLIVPQNFNIKETGKTFKENSLLKAKALFEILNNNQNVFGEDSGLCIEALNLEP
GIYSKRYDTYKLCKKLSTNEKNQLILDLMKNEKNRKAYFICNISYISKNGQILNFEGIIKGKIALSLNDKKNYGFGYDSI
FLTKNNKKLSDLTLEEKNKISHRGIAFLKFKKFLLKSLFNS

Sequences:

>Translated_201_residues
MKTLFFATTNENKINEVKNILDIPNLNLIVPQNFNIKETGKTFKENSLLKAKALFEILNNNQNVFGEDSGLCIEALNLEP
GIYSKRYDTYKLCKKLSTNEKNQLILDLMKNEKNRKAYFICNISYISKNGQILNFEGIIKGKIALSLNDKKNYGFGYDSI
FLTKNNKKLSDLTLEEKNKISHRGIAFLKFKKFLLKSLFNS
>Mature_201_residues
MKTLFFATTNENKINEVKNILDIPNLNLIVPQNFNIKETGKTFKENSLLKAKALFEILNNNQNVFGEDSGLCIEALNLEP
GIYSKRYDTYKLCKKLSTNEKNQLILDLMKNEKNRKAYFICNISYISKNGQILNFEGIIKGKIALSLNDKKNYGFGYDSI
FLTKNNKKLSDLTLEEKNKISHRGIAFLKFKKFLLKSLFNS

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=210, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6322529, Length=204, Percent_Identity=29.4117647058824, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 23138; Mature: 23138

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLFFATTNENKINEVKNILDIPNLNLIVPQNFNIKETGKTFKENSLLKAKALFEILNN
CCEEEEEECCCCHHHHHHHHHCCCCCEEEECCCCCCHHCCCCHHHCCHHHHHHHHHHHCC
NQNVFGEDSGLCIEALNLEPGIYSKRYDTYKLCKKLSTNEKNQLILDLMKNEKNRKAYFI
CCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCHHHHHEECCCCCCCEEEEE
CNISYISKNGQILNFEGIIKGKIALSLNDKKNYGFGYDSIFLTKNNKKLSDLTLEEKNKI
EEEEEECCCCCEEEECCEEEEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCHHCCC
SHRGIAFLKFKKFLLKSLFNS
CCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTLFFATTNENKINEVKNILDIPNLNLIVPQNFNIKETGKTFKENSLLKAKALFEILNN
CCEEEEEECCCCHHHHHHHHHCCCCCEEEECCCCCCHHCCCCHHHCCHHHHHHHHHHHCC
NQNVFGEDSGLCIEALNLEPGIYSKRYDTYKLCKKLSTNEKNQLILDLMKNEKNRKAYFI
CCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCHHHHHEECCCCCCCEEEEE
CNISYISKNGQILNFEGIIKGKIALSLNDKKNYGFGYDSIFLTKNNKKLSDLTLEEKNKI
EEEEEECCCCCEEEECCEEEEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCHHCCC
SHRGIAFLKFKKFLLKSLFNS
CCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA