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The map label for this gene is glpD [H]

Identifier: 15594588

GI number: 15594588

Start: 248506

End: 250089

Strand: Direct

Name: glpD [H]

Synonym: BB0243

Alternate gene names: 15594588

Gene position: 248506-250089 (Clockwise)

Preceding gene: 15594587

Following gene: 15594592

Centisome position: 27.29

GC content: 30.11

Gene sequence:

>1584_bases
ATGGAGGAATATTTAAATTTCATGAATAATAACAAAGAAACAAAATTAAAAGATCTTGAAAATCAAGAATTTGATCTTAT
AATAATTGGAGGGGGCGCAACAGGTCTTGGCATTGCGGTAGACGCAATTACAAGGGGGTATAAAGCAATACTTATAGAAA
AATTTGATTATGCAAAAGGAACTTCCTCTAGATCAAGCAAATTAATTCACGGTGGAGTAAGATATTTAGCCCAATGGAAT
ATTTCTTTAGTTAAAGAAGCTTTGCGCGAAAAAGCCATTCTTGAGAAAAATGCACCCCATTTAATTAACGAATGTGCACT
TATCACGCCTATTTATAATGTTTTAGAAATACCTTATTATTATTTTGGATTAAGTTACTACCACAATCTTATGGGTAAAG
AAAAAACTACTAAATACAAAACTAAATTACTATCCAAAAAATCTACCATTGAAAAAGCTCCCAATATTAAAACAGAGGGC
CTTAAATGCTCTGTTCTATATTACGATGATTCATTCGATGATGCTAGAATGGCAATAACATTGTTAAGAACCTTTACCGA
AAAAGGAGGCATTGCCCTTAACTATACAGAACTTAAAAAATTCAACAAAGAAAACGGAAAGCTTTCGGGAGTTCTTATAC
AAAATAAATTGTCAAAAGAACAAATTTCATTAAAAAGCAAATGCATAATAAACGCAACAGGAATATTTTCAGATGAAATA
AGAAGGTTGGATGATGAAAAAGCCTTAAACATCATTAAACCTTCCCAAGGTAGCCATTTAGTAGTCAAAAAAGACAAATT
TCCCAAAAATCATGCAATATTAATACCTAAAACTAGTGATAATAGGATTTTATTCGCTATTCCTTGGTATGATAGTGTTG
TTTGTGGAAGCACTGACATTCCAATAAAAGAGATAGAAGAAGAACCCAAAAGATTTGAAGAAGAGATTGACTTTATAATA
AATAATTTAAATAACTATTTAAATATTAAAATAGAAAAATCAGATGTAAAAAGTGTATATACCGGAATAAGGCCATTAAT
AATGGATCCAAAAGCTCAAGGAAACACTTCAAAAATCTCAAGAAACGAAAAAATATTTATATCAGATTCAAATCTTATTA
CAATAGCGGGGGGGAAATATACCACATATAGAAAAATGGCAGAAAAAACCTTGCTTAAGGCCATAGAACAAAATTTAATA
CCAAATCGTGCACCAACTACAGAAGATTTAAAGTTGCACGGCTACCTTAAAAAAGAAGAAGCAATGAAAATTCCTGAACC
TTTTAGAGCTTATGGCAGCGACTTTGAAATTCTAAAAAATATGGAGGGTTTTGACAAAAAAATACACGAAAACTTGGATT
TAAATGAAGCTCAAATAGATTTTTCAATTAAATTTGAACAAGCCAAAACTATTGAGGATGTTTTAGCAAGAAGAACAAGA
TCACTACCTTTAAATCCTCAAGCTACAATTGAGGCTGCTCCAAGAGTTGCTGAAATAATGATGGAAAAATTAAATAAATC
TGAAGAGTGGAAAAATGAACAAATAAAAAACTTTTTAGAAATAAGTAAAAAATATTTAATTTAA

Upstream 100 bases:

>100_bases
TGCAATTGGTCTATAGTGCTATTCAATAAAATTAAAACAAATGGTCTTTTCGAATTTCTTCAATCTAGTATTTAACTAAA
AAGAAAAGAAATTAACCAAA

Downstream 100 bases:

>100_bases
AATTAATTTTTATATTAAACAAAGGGATTGTTAAGCAATCCCTTTTAATTTTAAAACCTAAAACATTAAAAAGTCTTACA
CCCAATTCACATTAGCAAAT

Product: glycerol-3-phosphate dehydrogenase, anaerobic

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MEEYLNFMNNNKETKLKDLENQEFDLIIIGGGATGLGIAVDAITRGYKAILIEKFDYAKGTSSRSSKLIHGGVRYLAQWN
ISLVKEALREKAILEKNAPHLINECALITPIYNVLEIPYYYFGLSYYHNLMGKEKTTKYKTKLLSKKSTIEKAPNIKTEG
LKCSVLYYDDSFDDARMAITLLRTFTEKGGIALNYTELKKFNKENGKLSGVLIQNKLSKEQISLKSKCIINATGIFSDEI
RRLDDEKALNIIKPSQGSHLVVKKDKFPKNHAILIPKTSDNRILFAIPWYDSVVCGSTDIPIKEIEEEPKRFEEEIDFII
NNLNNYLNIKIEKSDVKSVYTGIRPLIMDPKAQGNTSKISRNEKIFISDSNLITIAGGKYTTYRKMAEKTLLKAIEQNLI
PNRAPTTEDLKLHGYLKKEEAMKIPEPFRAYGSDFEILKNMEGFDKKIHENLDLNEAQIDFSIKFEQAKTIEDVLARRTR
SLPLNPQATIEAAPRVAEIMMEKLNKSEEWKNEQIKNFLEISKKYLI

Sequences:

>Translated_527_residues
MEEYLNFMNNNKETKLKDLENQEFDLIIIGGGATGLGIAVDAITRGYKAILIEKFDYAKGTSSRSSKLIHGGVRYLAQWN
ISLVKEALREKAILEKNAPHLINECALITPIYNVLEIPYYYFGLSYYHNLMGKEKTTKYKTKLLSKKSTIEKAPNIKTEG
LKCSVLYYDDSFDDARMAITLLRTFTEKGGIALNYTELKKFNKENGKLSGVLIQNKLSKEQISLKSKCIINATGIFSDEI
RRLDDEKALNIIKPSQGSHLVVKKDKFPKNHAILIPKTSDNRILFAIPWYDSVVCGSTDIPIKEIEEEPKRFEEEIDFII
NNLNNYLNIKIEKSDVKSVYTGIRPLIMDPKAQGNTSKISRNEKIFISDSNLITIAGGKYTTYRKMAEKTLLKAIEQNLI
PNRAPTTEDLKLHGYLKKEEAMKIPEPFRAYGSDFEILKNMEGFDKKIHENLDLNEAQIDFSIKFEQAKTIEDVLARRTR
SLPLNPQATIEAAPRVAEIMMEKLNKSEEWKNEQIKNFLEISKKYLI
>Mature_527_residues
MEEYLNFMNNNKETKLKDLENQEFDLIIIGGGATGLGIAVDAITRGYKAILIEKFDYAKGTSSRSSKLIHGGVRYLAQWN
ISLVKEALREKAILEKNAPHLINECALITPIYNVLEIPYYYFGLSYYHNLMGKEKTTKYKTKLLSKKSTIEKAPNIKTEG
LKCSVLYYDDSFDDARMAITLLRTFTEKGGIALNYTELKKFNKENGKLSGVLIQNKLSKEQISLKSKCIINATGIFSDEI
RRLDDEKALNIIKPSQGSHLVVKKDKFPKNHAILIPKTSDNRILFAIPWYDSVVCGSTDIPIKEIEEEPKRFEEEIDFII
NNLNNYLNIKIEKSDVKSVYTGIRPLIMDPKAQGNTSKISRNEKIFISDSNLITIAGGKYTTYRKMAEKTLLKAIEQNLI
PNRAPTTEDLKLHGYLKKEEAMKIPEPFRAYGSDFEILKNMEGFDKKIHENLDLNEAQIDFSIKFEQAKTIEDVLARRTR
SLPLNPQATIEAAPRVAEIMMEKLNKSEEWKNEQIKNFLEISKKYLI

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=564, Percent_Identity=37.2340425531915, Blast_Score=351, Evalue=1e-96,
Organism=Homo sapiens, GI285002231, Length=564, Percent_Identity=37.2340425531915, Blast_Score=351, Evalue=1e-96,
Organism=Escherichia coli, GI2367226, Length=486, Percent_Identity=30.4526748971193, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1788574, Length=509, Percent_Identity=26.3261296660118, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17509253, Length=541, Percent_Identity=34.3807763401109, Blast_Score=290, Evalue=1e-78,
Organism=Caenorhabditis elegans, GI115534726, Length=543, Percent_Identity=35.5432780847145, Blast_Score=288, Evalue=4e-78,
Organism=Saccharomyces cerevisiae, GI6322036, Length=589, Percent_Identity=34.634974533107, Blast_Score=303, Evalue=4e-83,
Organism=Drosophila melanogaster, GI161077125, Length=539, Percent_Identity=38.7755102040816, Blast_Score=335, Evalue=4e-92,
Organism=Drosophila melanogaster, GI24653942, Length=539, Percent_Identity=38.7755102040816, Blast_Score=335, Evalue=4e-92,
Organism=Drosophila melanogaster, GI24653944, Length=539, Percent_Identity=38.7755102040816, Blast_Score=335, Evalue=4e-92,
Organism=Drosophila melanogaster, GI20130025, Length=539, Percent_Identity=38.7755102040816, Blast_Score=335, Evalue=4e-92,
Organism=Drosophila melanogaster, GI24586295, Length=552, Percent_Identity=29.5289855072464, Blast_Score=231, Evalue=8e-61,
Organism=Drosophila melanogaster, GI19921278, Length=537, Percent_Identity=29.608938547486, Blast_Score=212, Evalue=5e-55,
Organism=Drosophila melanogaster, GI45550977, Length=390, Percent_Identity=26.9230769230769, Blast_Score=147, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 60251; Mature: 60251

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEYLNFMNNNKETKLKDLENQEFDLIIIGGGATGLGIAVDAITRGYKAILIEKFDYAKG
CHHHHHHHCCCCCCHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEEECCCCCC
TSSRSSKLIHGGVRYLAQWNISLVKEALREKAILEKNAPHLINECALITPIYNVLEIPYY
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHH
YFGLSYYHNLMGKEKTTKYKTKLLSKKSTIEKAPNIKTEGLKCSVLYYDDSFDDARMAIT
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHHHH
LLRTFTEKGGIALNYTELKKFNKENGKLSGVLIQNKLSKEQISLKSKCIINATGIFSDEI
HHHHHHHCCCEEEEHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHCCEEEEECCCCHHHH
RRLDDEKALNIIKPSQGSHLVVKKDKFPKNHAILIPKTSDNRILFAIPWYDSVVCGSTDI
HHCCCHHCCEEECCCCCCEEEEECCCCCCCCEEEEEECCCCEEEEEECCCCCEEECCCCC
PIKEIEEEPKRFEEEIDFIINNLNNYLNIKIEKSDVKSVYTGIRPLIMDPKAQGNTSKIS
CHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHCCCCEEECCCCCCCCCCCC
RNEKIFISDSNLITIAGGKYTTYRKMAEKTLLKAIEQNLIPNRAPTTEDLKLHGYLKKEE
CCCEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECHHH
AMKIPEPFRAYGSDFEILKNMEGFDKKIHENLDLNEAQIDFSIKFEQAKTIEDVLARRTR
CCCCCCHHHHCCCCHHHHHCCCHHHHHHHCCCCCCCEEEEEEEEECHHHHHHHHHHHHHC
SLPLNPQATIEAAPRVAEIMMEKLNKSEEWKNEQIKNFLEISKKYLI
CCCCCCCHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEEYLNFMNNNKETKLKDLENQEFDLIIIGGGATGLGIAVDAITRGYKAILIEKFDYAKG
CHHHHHHHCCCCCCHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEEECCCCCC
TSSRSSKLIHGGVRYLAQWNISLVKEALREKAILEKNAPHLINECALITPIYNVLEIPYY
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHH
YFGLSYYHNLMGKEKTTKYKTKLLSKKSTIEKAPNIKTEGLKCSVLYYDDSFDDARMAIT
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHHHH
LLRTFTEKGGIALNYTELKKFNKENGKLSGVLIQNKLSKEQISLKSKCIINATGIFSDEI
HHHHHHHCCCEEEEHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHCCEEEEECCCCHHHH
RRLDDEKALNIIKPSQGSHLVVKKDKFPKNHAILIPKTSDNRILFAIPWYDSVVCGSTDI
HHCCCHHCCEEECCCCCCEEEEECCCCCCCCEEEEEECCCCEEEEEECCCCCEEECCCCC
PIKEIEEEPKRFEEEIDFIINNLNNYLNIKIEKSDVKSVYTGIRPLIMDPKAQGNTSKIS
CHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHCCCCEEECCCCCCCCCCCC
RNEKIFISDSNLITIAGGKYTTYRKMAEKTLLKAIEQNLIPNRAPTTEDLKLHGYLKKEE
CCCEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECHHH
AMKIPEPFRAYGSDFEILKNMEGFDKKIHENLDLNEAQIDFSIKFEQAKTIEDVLARRTR
CCCCCCHHHHCCCCHHHHHCCCHHHHHHHCCCCCCCEEEEEEEEECHHHHHHHHHHHHHC
SLPLNPQATIEAAPRVAEIMMEKLNKSEEWKNEQIKNFLEISKKYLI
CCCCCCCHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2127799; 9579061; 9384377; 1809833 [H]