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The map label for this gene is hflC

Identifier: 15594549

GI number: 15594549

Start: 205073

End: 206044

Strand: Direct

Name: hflC

Synonym: BB0204

Alternate gene names: 15594549

Gene position: 205073-206044 (Clockwise)

Preceding gene: 15594548

Following gene: 15594550

Centisome position: 22.52

GC content: 30.14

Gene sequence:

>972_bases
ATGAAATTTATAATAAATCTTTTATTATCTACTATAAAGATTATAACCTTTACAGTAATAGTTTGCTTGACTATTTTGTC
TATTTTCCAGCCAATTTATATTTTGAAAGAAAATGAAATTTCAATAACCACTCGACTTGGAAAAATTCAAAGAACTGAAA
ATTTAGCTGGACTTAAATATAAAATACCATTAATTGAAAATGTGCAAATATTTCCCAAAATCATTCTTAGATGGGATGGA
GAACCTCAAAGAATCCCAACAGGAGGGGAAGAAAAGCAATTAATATGGATTGATACAACTGCTAGATGGAAAATTGCAGA
CATAAATAAATTTTACACAACAATAAAAACAATGAGTAGAGCTTACGTTAGAATTGATGCAGCAATTGAACCTGCTGTTA
GGGGGGTTATTGCAAAATACCCTTTGCTTGAAATTATAAGAAGCTCAAACGATCCTATTCAACGTTTGTCTAATGGAATA
CTCACCCCACAAGAAACAAAAATTAACGGTATTTATAAAATAACAAAAGGACGAAAGATAATCGAAAAAGAAATAATTCG
TATAGCAAACAACAATACCAAAGATATTGGAATTGAAATTGTAGACGTACTAATAAGAAAAGTTACTTATGACCCAAGCC
TTATTGAATCTGTAAACAACAGAATGATCTCAGAAAGACAACAAATCGCAGAAGAACAAAGAAGCATAGGATTAGCTGAA
AAAACAGAAATTCTTGGAAGCATAGAAAAAGAAAAACTGAAAATATTAAGTGAAGCAAAAGCCACTGCTGCAAAAATAAA
AGCCGAAGGGGATAGAGAAGCCGCAAAAATTTATTCAAATGCATATGGCAAAAATATTGAATTTTACAAATTCTGGCAGG
CATTAGAAAGCTATAAAGCAGTATTAAAAGATAAAAGAAAAATTTTCTCAACAGACATGGATTTCTTTCAATATCTTCAC
AAAAGAAATTGA

Upstream 100 bases:

>100_bases
TTACAATGAAACCATGAAAGAAATACTTGAAAACAAAGATAACATTGAATTAATTGACAAAAACTTCAAAAATTTTCTAC
CATTTAAAGAGGTAAAATAA

Downstream 100 bases:

>100_bases
AAGTTTATTAGTATAAATTTTTTCTTTAAATACCTGTAAAATATATATTATTAATCTATTATTATAGATTAAATAATAAT
GCAAATCTTTATTTAAATTT

Product: lambda CII stability-governing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MKFIINLLLSTIKIITFTVIVCLTILSIFQPIYILKENEISITTRLGKIQRTENLAGLKYKIPLIENVQIFPKIILRWDG
EPQRIPTGGEEKQLIWIDTTARWKIADINKFYTTIKTMSRAYVRIDAAIEPAVRGVIAKYPLLEIIRSSNDPIQRLSNGI
LTPQETKINGIYKITKGRKIIEKEIIRIANNNTKDIGIEIVDVLIRKVTYDPSLIESVNNRMISERQQIAEEQRSIGLAE
KTEILGSIEKEKLKILSEAKATAAKIKAEGDREAAKIYSNAYGKNIEFYKFWQALESYKAVLKDKRKIFSTDMDFFQYLH
KRN

Sequences:

>Translated_323_residues
MKFIINLLLSTIKIITFTVIVCLTILSIFQPIYILKENEISITTRLGKIQRTENLAGLKYKIPLIENVQIFPKIILRWDG
EPQRIPTGGEEKQLIWIDTTARWKIADINKFYTTIKTMSRAYVRIDAAIEPAVRGVIAKYPLLEIIRSSNDPIQRLSNGI
LTPQETKINGIYKITKGRKIIEKEIIRIANNNTKDIGIEIVDVLIRKVTYDPSLIESVNNRMISERQQIAEEQRSIGLAE
KTEILGSIEKEKLKILSEAKATAAKIKAEGDREAAKIYSNAYGKNIEFYKFWQALESYKAVLKDKRKIFSTDMDFFQYLH
KRN
>Mature_323_residues
MKFIINLLLSTIKIITFTVIVCLTILSIFQPIYILKENEISITTRLGKIQRTENLAGLKYKIPLIENVQIFPKIILRWDG
EPQRIPTGGEEKQLIWIDTTARWKIADINKFYTTIKTMSRAYVRIDAAIEPAVRGVIAKYPLLEIIRSSNDPIQRLSNGI
LTPQETKINGIYKITKGRKIIEKEIIRIANNNTKDIGIEIVDVLIRKVTYDPSLIESVNNRMISERQQIAEEQRSIGLAE
KTEILGSIEKEKLKILSEAKATAAKIKAEGDREAAKIYSNAYGKNIEFYKFWQALESYKAVLKDKRKIFSTDMDFFQYLH
KRN

Specific function: HflC and HflK could encode or regulate a protease

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily

Homologues:

Organism=Escherichia coli, GI1790617, Length=318, Percent_Identity=27.6729559748428, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFLC_BORBU (O51222)

Other databases:

- EMBL:   AE000783
- PIR:   D70125
- RefSeq:   NP_212338.1
- ProteinModelPortal:   O51222
- EnsemblBacteria:   EBBORT00000009138
- GeneID:   1195040
- GenomeReviews:   AE000783_GR
- KEGG:   bbu:BB0204
- NMPDR:   fig|224326.1.peg.588
- TIGR:   BB_0204
- GeneTree:   EBGT00050000007136
- HOGENOM:   HBG427952
- OMA:   NEISITT
- PhylomeDB:   O51222
- ProtClustDB:   CLSK507430
- BioCyc:   BBUR224326:BB_0204-MONOMER
- InterPro:   IPR001107
- InterPro:   IPR010200
- SMART:   SM00244
- TIGRFAMs:   TIGR01932

Pfam domain/function: PF01145 Band_7

EC number: 3.4.-.-

Molecular weight: Translated: 37194; Mature: 37194

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xaf55e60)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFIINLLLSTIKIITFTVIVCLTILSIFQPIYILKENEISITTRLGKIQRTENLAGLKY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEEHHHHHHHHCCCCCCEE
KIPLIENVQIFPKIILRWDGEPQRIPTGGEEKQLIWIDTTARWKIADINKFYTTIKTMSR
ECCCCCCHHHHHHHHEEECCCCCCCCCCCCCCEEEEEECCCCEEEHHHHHHHHHHHHHHH
AYVRIDAAIEPAVRGVIAKYPLLEIIRSSNDPIQRLSNGILTPQETKINGIYKITKGRKI
HHEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCEEEECCCHHH
IEKEIIRIANNNTKDIGIEIVDVLIRKVTYDPSLIESVNNRMISERQQIAEEQRSIGLAE
HHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
KTEILGSIEKEKLKILSEAKATAAKIKAEGDREAAKIYSNAYGKNIEFYKFWQALESYKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
VLKDKRKIFSTDMDFFQYLHKRN
HHHHHHHHHHCCHHHHHHHHCCH
>Mature Secondary Structure
MKFIINLLLSTIKIITFTVIVCLTILSIFQPIYILKENEISITTRLGKIQRTENLAGLKY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEEHHHHHHHHCCCCCCEE
KIPLIENVQIFPKIILRWDGEPQRIPTGGEEKQLIWIDTTARWKIADINKFYTTIKTMSR
ECCCCCCHHHHHHHHEEECCCCCCCCCCCCCCEEEEEECCCCEEEHHHHHHHHHHHHHHH
AYVRIDAAIEPAVRGVIAKYPLLEIIRSSNDPIQRLSNGILTPQETKINGIYKITKGRKI
HHEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCEEEECCCHHH
IEKEIIRIANNNTKDIGIEIVDVLIRKVTYDPSLIESVNNRMISERQQIAEEQRSIGLAE
HHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
KTEILGSIEKEKLKILSEAKATAAKIKAEGDREAAKIYSNAYGKNIEFYKFWQALESYKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
VLKDKRKIFSTDMDFFQYLHKRN
HHHHHHHHHHCCHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9403685