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The map label for this gene is hflK

Identifier: 15594548

GI number: 15594548

Start: 204137

End: 205072

Strand: Direct

Name: hflK

Synonym: BB0203

Alternate gene names: 15594548

Gene position: 204137-205072 (Clockwise)

Preceding gene: 15594547

Following gene: 15594549

Centisome position: 22.41

GC content: 28.31

Gene sequence:

>936_bases
ATGTTTGACATAAAACAAATTTTTAATAAAACTTATGAATATTTAATAATTATTATTACCCTGATACTAATATCAATAAT
AGTTATTGCAAACATATTCATAGTAGGGCCATCAGAAGAGGCAATTGTACTTCGCCTTGGCAAGCTTAACAGAACTCTTG
ATTCAGGAATACACGTCAAGATTCCATTAATTGAAGAAAAATTTATCGTACCTGTAAAAATAGTCCAAGAAATTAAATTT
GGATTTCTAATATCTCCAAGCGATATTAGAGAAAATGATAATGCAAACGACGAAAGCAGGATTATTACTGGGGATTTAAA
TATCATAAACATTGAATGGTTAGTGCAATACAAAATAAGAGATCCTTATTCATTCAAATTTAAAGTAGAAGATCCTGAAA
CAACAATTAAAGATATTGCAAAGTCATCAATGAATAGATTGATTGGGGATAATACTATTTTTGAAATAATAAATGATAAC
AGAGTGGGAATAACAGAAGGCGTAAAATCTTCTATGAATGAAATAATAGATAATTATAATTTAGGCATTGATGTAGTGCA
AGTACAAATTAGAAATGCCCTACCCCCAAAAGGAAAAGTTTATGAAGCTTTTGAAGATGTAAACATTGCAATTCAAGACA
AAAATAAATACATAAACGAAGGGAGAAAAGAATTTAATCAAATAGTTCCCAAAATCAAAGGTGAAGCATTAAAGGTTATT
GAAGAAGCTAGAGGATATAAAGAAAGCAGAATAAACAATGCATTAGCAGACACAGAAATTTTCAATGCCATATTAGACGC
TTACTTAAAAAATCCCGATATCACAAAAGAAAGACTTTACAATGAAACCATGAAAGAAATACTTGAAAACAAAGATAACA
TTGAATTAATTGACAAAAACTTCAAAAATTTTCTACCATTTAAAGAGGTAAAATAA

Upstream 100 bases:

>100_bases
AATTCAGAATAATAAAATTGAAACAATAACTTTTATCAAATCTAAAAAGTAGTGACAAAATTCGCTTACTAAAAATAATT
TAAAACATTAGGAGAAGCAG

Downstream 100 bases:

>100_bases
ATGAAATTTATAATAAATCTTTTATTATCTACTATAAAGATTATAACCTTTACAGTAATAGTTTGCTTGACTATTTTGTC
TATTTTCCAGCCAATTTATA

Product: lambda CII stability-governing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MFDIKQIFNKTYEYLIIIITLILISIIVIANIFIVGPSEEAIVLRLGKLNRTLDSGIHVKIPLIEEKFIVPVKIVQEIKF
GFLISPSDIRENDNANDESRIITGDLNIINIEWLVQYKIRDPYSFKFKVEDPETTIKDIAKSSMNRLIGDNTIFEIINDN
RVGITEGVKSSMNEIIDNYNLGIDVVQVQIRNALPPKGKVYEAFEDVNIAIQDKNKYINEGRKEFNQIVPKIKGEALKVI
EEARGYKESRINNALADTEIFNAILDAYLKNPDITKERLYNETMKEILENKDNIELIDKNFKNFLPFKEVK

Sequences:

>Translated_311_residues
MFDIKQIFNKTYEYLIIIITLILISIIVIANIFIVGPSEEAIVLRLGKLNRTLDSGIHVKIPLIEEKFIVPVKIVQEIKF
GFLISPSDIRENDNANDESRIITGDLNIINIEWLVQYKIRDPYSFKFKVEDPETTIKDIAKSSMNRLIGDNTIFEIINDN
RVGITEGVKSSMNEIIDNYNLGIDVVQVQIRNALPPKGKVYEAFEDVNIAIQDKNKYINEGRKEFNQIVPKIKGEALKVI
EEARGYKESRINNALADTEIFNAILDAYLKNPDITKERLYNETMKEILENKDNIELIDKNFKNFLPFKEVK
>Mature_311_residues
MFDIKQIFNKTYEYLIIIITLILISIIVIANIFIVGPSEEAIVLRLGKLNRTLDSGIHVKIPLIEEKFIVPVKIVQEIKF
GFLISPSDIRENDNANDESRIITGDLNIINIEWLVQYKIRDPYSFKFKVEDPETTIKDIAKSSMNRLIGDNTIFEIINDN
RVGITEGVKSSMNEIIDNYNLGIDVVQVQIRNALPPKGKVYEAFEDVNIAIQDKNKYINEGRKEFNQIVPKIKGEALKVI
EEARGYKESRINNALADTEIFNAILDAYLKNPDITKERLYNETMKEILENKDNIELIDKNFKNFLPFKEVK

Specific function: HflC and HflK could encode or regulate a protease

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily

Homologues:

Organism=Escherichia coli, GI1790616, Length=271, Percent_Identity=28.0442804428044, Blast_Score=129, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFLK_BORBU (O51221)

Other databases:

- EMBL:   AE000783
- PIR:   C70125
- RefSeq:   NP_212337.1
- ProteinModelPortal:   O51221
- SMR:   O51221
- EnsemblBacteria:   EBBORT00000008936
- GeneID:   1195039
- GenomeReviews:   AE000783_GR
- KEGG:   bbu:BB0203
- NMPDR:   fig|224326.1.peg.587
- TIGR:   BB_0203
- GeneTree:   EBGT00050000007135
- HOGENOM:   HBG465357
- OMA:   VLAVQMQ
- PhylomeDB:   O51221
- ProtClustDB:   CLSK507429
- BioCyc:   BBUR224326:BB_0203-MONOMER
- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR001972
- PANTHER:   PTHR10264
- SMART:   SM00244
- TIGRFAMs:   TIGR01933

Pfam domain/function: PF01145 Band_7

EC number: NA

Molecular weight: Translated: 35826; Mature: 35826

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xb32d254)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDIKQIFNKTYEYLIIIITLILISIIVIANIFIVGPSEEAIVLRLGKLNRTLDSGIHVK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEECHHHHHHCCCCEEE
IPLIEEKFIVPVKIVQEIKFGFLISPSDIRENDNANDESRIITGDLNIINIEWLVQYKIR
EEEECCCCCHHHHHHHHHHHCEEECCHHCCCCCCCCCCCEEEECCCEEEEEEEEEEEEEC
DPYSFKFKVEDPETTIKDIAKSSMNRLIGDNTIFEIINDNRVGITEGVKSSMNEIIDNYN
CCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCC
LGIDVVQVQIRNALPPKGKVYEAFEDVNIAIQDKNKYINEGRKEFNQIVPKIKGEALKVI
CCEEEEEEEEHHCCCCCCHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHCHHHHHHH
EEARGYKESRINNALADTEIFNAILDAYLKNPDITKERLYNETMKEILENKDNIELIDKN
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEHHHH
FKNFLPFKEVK
HHHCCCCCCCH
>Mature Secondary Structure
MFDIKQIFNKTYEYLIIIITLILISIIVIANIFIVGPSEEAIVLRLGKLNRTLDSGIHVK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEECHHHHHHCCCCEEE
IPLIEEKFIVPVKIVQEIKFGFLISPSDIRENDNANDESRIITGDLNIINIEWLVQYKIR
EEEECCCCCHHHHHHHHHHHCEEECCHHCCCCCCCCCCCEEEECCCEEEEEEEEEEEEEC
DPYSFKFKVEDPETTIKDIAKSSMNRLIGDNTIFEIINDNRVGITEGVKSSMNEIIDNYN
CCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCC
LGIDVVQVQIRNALPPKGKVYEAFEDVNIAIQDKNKYINEGRKEFNQIVPKIKGEALKVI
CCEEEEEEEEHHCCCCCCHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHCHHHHHHH
EEARGYKESRINNALADTEIFNAILDAYLKNPDITKERLYNETMKEILENKDNIELIDKN
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEHHHH
FKNFLPFKEVK
HHHCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9403685