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The map label for this gene is bceR [H]

Identifier: 154687161

GI number: 154687161

Start: 2860627

End: 2861322

Strand: Reverse

Name: bceR [H]

Synonym: RBAM_027330

Alternate gene names: 154687161

Gene position: 2861322-2860627 (Counterclockwise)

Preceding gene: 154687162

Following gene: 154687160

Centisome position: 73.02

GC content: 45.98

Gene sequence:

>696_bases
ATGTTTCACATTTTGTTAATAGAAGATGATAACACTTTGTTTCATGAGATGAAAGAGAGATTAACGGGCTGGTCATTTGC
GGTGCACGGAATAAAAGATTTCAGCCGGGTCATCCGGGAGTTTACCGAAATCAAGCCTGATTTGGTGATCATTGATGTAC
AGCTGCCGAAATTTGACGGCTTTCATTGGTGCAGAATGATACGCTCCCAATCAAACGTGCCGATTCTCTTTTTGTCCTCG
CGCGATCATCCCGCGGATATGGTCATGTCGATGCAGCTCGGGGCAGATGATTTTATTCAGAAGCCTTTTCACTTTGATGT
GTTAATCGCGAAAATACAGGCGGTGTTCCGCCGTGTGCATCAATACGGCACAGAACCGGCGCTGATGAAAAGATGGTGCG
GAGCGGTCATTGACACAGAAACCAACACGGTCAGCCGTAAAAACGGTTCGGTCGAGCTGACCAAAAACGAAATGCTGATC
TTAAAACTGCTGGCTGAGCAGAAAAATAAAATCGTCAGCCGGGAAGAACTCATCAGAAGCCTATGGAATGATGAGCGTTT
CGTCAGTGATAATACGCTGACGGTGAATGTCAACCGGCTGCGGAAAAAACTCGAACAATTAGGCATCGGGAAAATGATTG
AAACCAAGGTGGGGCAGGGATACATCGCAAAGGAAGAAGACGGTCTTTATGATTAA

Upstream 100 bases:

>100_bases
AACCAACGTTCTGACTGCATTAAGAAGAGAACTGTAAAGGAAAAAAGCCGGCTGGACATCAGCCGGTTTTTCCTCTATCT
ATCAGAAAAGGGCGGATACC

Downstream 100 bases:

>100_bases
ATCATTTCTGCTCGAAAGAAAGAGCTGGATCGCGATGTTTCTTTTTCAGCAGGCTGTGCTCCTTTTTGCGGCATATATTG
ATCCGTCTATTCCGTTTTTT

Product: BceR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MFHILLIEDDNTLFHEMKERLTGWSFAVHGIKDFSRVIREFTEIKPDLVIIDVQLPKFDGFHWCRMIRSQSNVPILFLSS
RDHPADMVMSMQLGADDFIQKPFHFDVLIAKIQAVFRRVHQYGTEPALMKRWCGAVIDTETNTVSRKNGSVELTKNEMLI
LKLLAEQKNKIVSREELIRSLWNDERFVSDNTLTVNVNRLRKKLEQLGIGKMIETKVGQGYIAKEEDGLYD

Sequences:

>Translated_231_residues
MFHILLIEDDNTLFHEMKERLTGWSFAVHGIKDFSRVIREFTEIKPDLVIIDVQLPKFDGFHWCRMIRSQSNVPILFLSS
RDHPADMVMSMQLGADDFIQKPFHFDVLIAKIQAVFRRVHQYGTEPALMKRWCGAVIDTETNTVSRKNGSVELTKNEMLI
LKLLAEQKNKIVSREELIRSLWNDERFVSDNTLTVNVNRLRKKLEQLGIGKMIETKVGQGYIAKEEDGLYD
>Mature_231_residues
MFHILLIEDDNTLFHEMKERLTGWSFAVHGIKDFSRVIREFTEIKPDLVIIDVQLPKFDGFHWCRMIRSQSNVPILFLSS
RDHPADMVMSMQLGADDFIQKPFHFDVLIAKIQAVFRRVHQYGTEPALMKRWCGAVIDTETNTVSRKNGSVELTKNEMLI
LKLLAEQKNKIVSREELIRSLWNDERFVSDNTLTVNVNRLRKKLEQLGIGKMIETKVGQGYIAKEEDGLYD

Specific function: Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. When activated by BceS, binds to the upstream region of the bceAB promoter and up-regulates the expression of these two genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=30.5309734513274, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1786599, Length=221, Percent_Identity=28.9592760180996, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=28.8288288288288, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1790860, Length=220, Percent_Identity=29.0909090909091, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=30, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=29.7297297297297, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=28.82096069869, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=27.8761061946903, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=28.5714285714286, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=28.3185840707965, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=29.3859649122807, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790552, Length=233, Percent_Identity=30.4721030042918, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=25.9911894273128, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=26.271186440678, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26868; Mature: 26868

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFHILLIEDDNTLFHEMKERLTGWSFAVHGIKDFSRVIREFTEIKPDLVIIDVQLPKFDG
CEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
FHWCRMIRSQSNVPILFLSSRDHPADMVMSMQLGADDFIQKPFHFDVLIAKIQAVFRRVH
HHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHH
QYGTEPALMKRWCGAVIDTETNTVSRKNGSVELTKNEMLILKLLAEQKNKIVSREELIRS
HCCCCHHHHHHHCCCEECCCCCEEECCCCCEEEECCHHHHHHHHHHHHHHCCCHHHHHHH
LWNDERFVSDNTLTVNVNRLRKKLEQLGIGKMIETKVGQGYIAKEEDGLYD
HCCCCEEECCCEEEEEHHHHHHHHHHCCCCHHHHHHCCCCEEECCCCCCCC
>Mature Secondary Structure
MFHILLIEDDNTLFHEMKERLTGWSFAVHGIKDFSRVIREFTEIKPDLVIIDVQLPKFDG
CEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
FHWCRMIRSQSNVPILFLSSRDHPADMVMSMQLGADDFIQKPFHFDVLIAKIQAVFRRVH
HHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHH
QYGTEPALMKRWCGAVIDTETNTVSRKNGSVELTKNEMLILKLLAEQKNKIVSREELIRS
HCCCCHHHHHHHCCCEECCCCCEEECCCCCEEEECCHHHHHHHHHHHHHHCCCHHHHHHH
LWNDERFVSDNTLTVNVNRLRKKLEQLGIGKMIETKVGQGYIAKEEDGLYD
HCCCCEEECCCEEEEEHHHHHHHHHHCCCCHHHHHHCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 14612242; 12890034 [H]