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The map label for this gene is bceS [H]

Identifier: 154687160

GI number: 154687160

Start: 2859630

End: 2860634

Strand: Reverse

Name: bceS [H]

Synonym: RBAM_027320

Alternate gene names: 154687160

Gene position: 2860634-2859630 (Counterclockwise)

Preceding gene: 154687161

Following gene: 154687159

Centisome position: 73.0

GC content: 46.87

Gene sequence:

>1005_bases
ATGATTAAATCATTTCTGCTCGAAAGAAAGAGCTGGATCGCGATGTTTCTTTTTCAGCAGGCTGTGCTCCTTTTTGCGGC
ATATATTGATCCGTCTATTCCGTTTTTTTCGGTGCTGTATTTCGTTTACCTGTCGCTTCTTGTGTTTCTTGTATTTCTCT
TGTTCCGCTATCGTAAAGAGACCGCCTATTATAAAAGCTTAAGAGAGTGGGACGCCAATTTAGACATGTCTTACCTTAAA
GCGCCTGACAGTCCGTTTGAGTCTATCGTTGAAGAAAGCATTGAAGGGCAGACAGAGCAGTTAAGAAAAAGCTCACTTGA
TCTTCAGGCGGCGTCAGAGCATGAAAAGGACGATCTGATGTCGTGGATTCACGAGGTCAAAACACCGCTGACAGCGATGC
ATCTCATGATCGAGCGCCTTGATGAACAGCCGCTCAAAGCCCCTTTGCTGTATGAATGGCTGCGGATTCACCATCTTCTG
GACCAGCAGCTTCATCAGAAACGATTGTCCTTTATTGAAAATGATTTATCATTCCAGCGCATTCAGCTCAGACCGCTCGT
TTTCAAAGAAATTAAAAATCTGCAATCTTGGTGTATACAAAAAGGGATCGGGTTTGACATTCAGCTTGATTCACCAGACG
TTCACAGTGACGGAAAATGGCTTTCCTTCATCATCAGGCAGCTGTTAAGCAATGCCGTCAAATACAGTGAGGCGGATGAC
ATTACCGTAAAAAGCTATGAACAAAACGGCCGGGTGCATGTGGATATCGAAGACCGCGGCATCGGCATCGAGCCCAAAGA
TCTTCCGCGCATTTTTGAAAAGGGATTTACCTCGACGCGAATGAGGCGTGATCACGCGTCAACGGGGATGGGCCTGTATT
TGGCTCAAAAAGCCGCGGCTCCGCTTCTTATCCAGATCAGCGTGCGCTCTGAGCCGGAAAGCGGCACGGTTTTTACCTTG
GTGTTTCCGAAACAGAACGATGCCGTCAGCATGTTCAGCGTGTGA

Upstream 100 bases:

>100_bases
GTCAACCGGCTGCGGAAAAAACTCGAACAATTAGGCATCGGGAAAATGATTGAAACCAAGGTGGGGCAGGGATACATCGC
AAAGGAAGAAGACGGTCTTT

Downstream 100 bases:

>100_bases
CAAAAGTGTCACATGCTTTTCTCTTTTGTTCGCTTAATCAAACGAAAAAAACGGCTTCTGTTTTTAAAATAAAGATAACC
AATGTAAAAGGAGAATCAGA

Product: BceS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MIKSFLLERKSWIAMFLFQQAVLLFAAYIDPSIPFFSVLYFVYLSLLVFLVFLLFRYRKETAYYKSLREWDANLDMSYLK
APDSPFESIVEESIEGQTEQLRKSSLDLQAASEHEKDDLMSWIHEVKTPLTAMHLMIERLDEQPLKAPLLYEWLRIHHLL
DQQLHQKRLSFIENDLSFQRIQLRPLVFKEIKNLQSWCIQKGIGFDIQLDSPDVHSDGKWLSFIIRQLLSNAVKYSEADD
ITVKSYEQNGRVHVDIEDRGIGIEPKDLPRIFEKGFTSTRMRRDHASTGMGLYLAQKAAAPLLIQISVRSEPESGTVFTL
VFPKQNDAVSMFSV

Sequences:

>Translated_334_residues
MIKSFLLERKSWIAMFLFQQAVLLFAAYIDPSIPFFSVLYFVYLSLLVFLVFLLFRYRKETAYYKSLREWDANLDMSYLK
APDSPFESIVEESIEGQTEQLRKSSLDLQAASEHEKDDLMSWIHEVKTPLTAMHLMIERLDEQPLKAPLLYEWLRIHHLL
DQQLHQKRLSFIENDLSFQRIQLRPLVFKEIKNLQSWCIQKGIGFDIQLDSPDVHSDGKWLSFIIRQLLSNAVKYSEADD
ITVKSYEQNGRVHVDIEDRGIGIEPKDLPRIFEKGFTSTRMRRDHASTGMGLYLAQKAAAPLLIQISVRSEPESGTVFTL
VFPKQNDAVSMFSV
>Mature_334_residues
MIKSFLLERKSWIAMFLFQQAVLLFAAYIDPSIPFFSVLYFVYLSLLVFLVFLLFRYRKETAYYKSLREWDANLDMSYLK
APDSPFESIVEESIEGQTEQLRKSSLDLQAASEHEKDDLMSWIHEVKTPLTAMHLMIERLDEQPLKAPLLYEWLRIHHLL
DQQLHQKRLSFIENDLSFQRIQLRPLVFKEIKNLQSWCIQKGIGFDIQLDSPDVHSDGKWLSFIIRQLLSNAVKYSEADD
ITVKSYEQNGRVHVDIEDRGIGIEPKDLPRIFEKGFTSTRMRRDHASTGMGLYLAQKAAAPLLIQISVRSEPESGTVFTL
VFPKQNDAVSMFSV

Specific function: Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. Activates BceR in response to extracellular bacitracin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=236, Percent_Identity=28.3898305084746, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786600, Length=213, Percent_Identity=25.3521126760563, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI145693157, Length=237, Percent_Identity=25.7383966244726, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789149, Length=249, Percent_Identity=27.710843373494, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788549, Length=220, Percent_Identity=28.1818181818182, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 38860; Mature: 38860

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKSFLLERKSWIAMFLFQQAVLLFAAYIDPSIPFFSVLYFVYLSLLVFLVFLLFRYRKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAYYKSLREWDANLDMSYLKAPDSPFESIVEESIEGQTEQLRKSSLDLQAASEHEKDDLM
HHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHCCCHHHHCCCHHHHH
SWIHEVKTPLTAMHLMIERLDEQPLKAPLLYEWLRIHHLLDQQLHQKRLSFIENDLSFQR
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
IQLRPLVFKEIKNLQSWCIQKGIGFDIQLDSPDVHSDGKWLSFIIRQLLSNAVKYSEADD
HHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
ITVKSYEQNGRVHVDIEDRGIGIEPKDLPRIFEKGFTSTRMRRDHASTGMGLYLAQKAAA
CEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHCCC
PLLIQISVRSEPESGTVFTLVFPKQNDAVSMFSV
CEEEEEEECCCCCCCCEEEEEECCCCCCEECCCC
>Mature Secondary Structure
MIKSFLLERKSWIAMFLFQQAVLLFAAYIDPSIPFFSVLYFVYLSLLVFLVFLLFRYRKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAYYKSLREWDANLDMSYLKAPDSPFESIVEESIEGQTEQLRKSSLDLQAASEHEKDDLM
HHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHCCCHHHHCCCHHHHH
SWIHEVKTPLTAMHLMIERLDEQPLKAPLLYEWLRIHHLLDQQLHQKRLSFIENDLSFQR
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
IQLRPLVFKEIKNLQSWCIQKGIGFDIQLDSPDVHSDGKWLSFIIRQLLSNAVKYSEADD
HHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
ITVKSYEQNGRVHVDIEDRGIGIEPKDLPRIFEKGFTSTRMRRDHASTGMGLYLAQKAAA
CEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHCCC
PLLIQISVRSEPESGTVFTLVFPKQNDAVSMFSV
CEEEEEEECCCCCCCCEEEEEECCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 14612242; 12890034 [H]