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The map label for this gene is nrdR

Identifier: 154687032

GI number: 154687032

Start: 2728357

End: 2728815

Strand: Reverse

Name: nrdR

Synonym: RBAM_026040

Alternate gene names: 154687032

Gene position: 2728815-2728357 (Counterclockwise)

Preceding gene: 154687033

Following gene: 154687031

Centisome position: 69.64

GC content: 44.88

Gene sequence:

>459_bases
TTGAAATGTCCTTCATGCCAGCACAACGGTTCCCGCGTACTTGATTCACGGCCTGCGGACGAAGGGAAATCAATCCGCAG
AAGGCGGGAATGCGAAGCCTGCCATTACCGCTTCACTACATTTGAGAAGTTTGAAGAGATGCCTCTGATCGTCGTGAAAA
AAGAAGGCGTCCGGGAAGAATTCAGCCGTGAAAAAATGCTGCGCGGGTTAATTAAAGCTTGTGAAAAAAGGCCCGTTCCT
TTAAAAACATTGGAAGACATGTGCTTTGACATTGAAAAAGAGCTGAGAAACCAAGGTGTATCTGAAGTCAAAAGCGAACT
TGTCGGAGAAATGGTAATGGACCGTCTGGCGAAAATCGATGAGGTGTCTTATGTCCGCTTTGCCTCCGTCTACCGGCAGT
TTAAGGATATAAACGTGTTTATCGATGAATTGAAAGATTTAATAAAGAAAGAACGCTGA

Upstream 100 bases:

>100_bases
CTCTCCCAACAAATAGGCTCATCCTAGAAACGTTGGCGGGCATTTACCGGAAGCTTGCGAACCGCATTACAGCAACGAAA
CAGATGGGAGCTGATCCAAT

Downstream 100 bases:

>100_bases
GAGAGCTAAGAGATTGTGTCTGGCTCTTTTCTCATGAGCAAAATTGGCATTTGATAGATCGCAGAAACGGTGTAAAATGA
GAGTAGAAACATATCGGAAG

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MKCPSCQHNGSRVLDSRPADEGKSIRRRRECEACHYRFTTFEKFEEMPLIVVKKEGVREEFSREKMLRGLIKACEKRPVP
LKTLEDMCFDIEKELRNQGVSEVKSELVGEMVMDRLAKIDEVSYVRFASVYRQFKDINVFIDELKDLIKKER

Sequences:

>Translated_152_residues
MKCPSCQHNGSRVLDSRPADEGKSIRRRRECEACHYRFTTFEKFEEMPLIVVKKEGVREEFSREKMLRGLIKACEKRPVP
LKTLEDMCFDIEKELRNQGVSEVKSELVGEMVMDRLAKIDEVSYVRFASVYRQFKDINVFIDELKDLIKKER
>Mature_152_residues
MKCPSCQHNGSRVLDSRPADEGKSIRRRRECEACHYRFTTFEKFEEMPLIVVKKEGVREEFSREKMLRGLIKACEKRPVP
LKTLEDMCFDIEKELRNQGVSEVKSELVGEMVMDRLAKIDEVSYVRFASVYRQFKDINVFIDELKDLIKKER

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=46.9387755102041, Blast_Score=130, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_BACA2 (A7Z7I6)

Other databases:

- EMBL:   CP000560
- RefSeq:   YP_001422193.1
- STRING:   A7Z7I6
- EnsemblBacteria:   EBBACT00000006317
- GeneID:   5460024
- GenomeReviews:   CP000560_GR
- KEGG:   bay:RBAM_026040
- eggNOG:   COG1327
- GeneTree:   EBGT00050000001207
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- BioCyc:   BAMY326423:RBAM_026040-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17969; Mature: 17969

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCPSCQHNGSRVLDSRPADEGKSIRRRRECEACHYRFTTFEKFEEMPLIVVKKEGVREE
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHH
FSREKMLRGLIKACEKRPVPLKTLEDMCFDIEKELRNQGVSEVKSELVGEMVMDRLAKID
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
EVSYVRFASVYRQFKDINVFIDELKDLIKKER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKCPSCQHNGSRVLDSRPADEGKSIRRRRECEACHYRFTTFEKFEEMPLIVVKKEGVREE
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHH
FSREKMLRGLIKACEKRPVPLKTLEDMCFDIEKELRNQGVSEVKSELVGEMVMDRLAKID
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
EVSYVRFASVYRQFKDINVFIDELKDLIKKER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA