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The map label for this gene is infC [H]

Identifier: 154687021

GI number: 154687021

Start: 2716281

End: 2716784

Strand: Reverse

Name: infC [H]

Synonym: RBAM_025930

Alternate gene names: 154687021

Gene position: 2716784-2716281 (Counterclockwise)

Preceding gene: 154687022

Following gene: 154687020

Centisome position: 69.33

GC content: 45.44

Gene sequence:

>504_bases
TTGGTTAATGAGGGTATCCGTGCACGTGAAGTTCGTCTGATCGGACAAAATGGCGATCAGCTCGGCATCAAGTCCCGTCA
GGAAGCACTTGAAATCGCCGGCCGCGCAAATCTTGACCTTGTGTTAGTTGCAGCAAATGCAAAACCGCCTGTCTGCCGCA
TCATGGACTACGGTAAGTTCAGATTCGAGCAGCAGAAAAAGGACAAAGAAGCACGCAAAAATCAAAAAATCATTAACTTA
AAAGAAGTTAGATTAAGTCCGACGATCGATGAGCATGACTTTAACACGAAATTGCGCAATGCGATTAAATTCCTTGAAAA
AGGCGATAAAGTGAAAGCTTCTATCCGCTTTAAAGGGCGCGCAATCACTCATAAAGAAATCGGCCAGCGCGTATTGGACC
GTTTCTCTGAAGCATGTGCGGAAGTTGCGACAGTCGAAACAAAACCAAAAATGGACGGCCGCAGCATGTTCTTAATGCTC
GCGCCGAAAAACGAAAAGCAATAA

Upstream 100 bases:

>100_bases
TCATGCCCGCACTTTTTGTTTGCCTGCAGAATGCAGTCAACAAGCGTTGTGAATCAATTCGAAGAAACTATGGAGGTGGC
TCATTATTAGCAAAGATCAA

Downstream 100 bases:

>100_bases
GGAGGAAATCCCATGCCAAAAATGAAAACTCACCGCGGATCTGCTAAACGTTTTAAAAAGACAGGTTCTGGGAAGTTAAA
ACGTTCTCATGCATATACAA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MVNEGIRAREVRLIGQNGDQLGIKSRQEALEIAGRANLDLVLVAANAKPPVCRIMDYGKFRFEQQKKDKEARKNQKIINL
KEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKASIRFKGRAITHKEIGQRVLDRFSEACAEVATVETKPKMDGRSMFLML
APKNEKQ

Sequences:

>Translated_167_residues
MVNEGIRAREVRLIGQNGDQLGIKSRQEALEIAGRANLDLVLVAANAKPPVCRIMDYGKFRFEQQKKDKEARKNQKIINL
KEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKASIRFKGRAITHKEIGQRVLDRFSEACAEVATVETKPKMDGRSMFLML
APKNEKQ
>Mature_167_residues
MVNEGIRAREVRLIGQNGDQLGIKSRQEALEIAGRANLDLVLVAANAKPPVCRIMDYGKFRFEQQKKDKEARKNQKIINL
KEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKASIRFKGRAITHKEIGQRVLDRFSEACAEVATVETKPKMDGRSMFLML
APKNEKQ

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=163, Percent_Identity=52.760736196319, Blast_Score=161, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 19033; Mature: 19033

Theoretical pI: Translated: 10.63; Mature: 10.63

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNEGIRAREVRLIGQNGDQLGIKSRQEALEIAGRANLDLVLVAANAKPPVCRIMDYGKF
CCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCEEEEECCCHH
RFEQQKKDKEARKNQKIINLKEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKASIRFKGR
HHHHHHHHHHHHHCCCEEEHEEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCC
AITHKEIGQRVLDRFSEACAEVATVETKPKMDGRSMFLMLAPKNEKQ
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MVNEGIRAREVRLIGQNGDQLGIKSRQEALEIAGRANLDLVLVAANAKPPVCRIMDYGKF
CCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCEEEEECCCHH
RFEQQKKDKEARKNQKIINLKEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKASIRFKGR
HHHHHHHHHHHHHCCCEEEHEEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCC
AITHKEIGQRVLDRFSEACAEVATVETKPKMDGRSMFLMLAPKNEKQ
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]