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The map label for this gene is yrvI

Identifier: 154686900

GI number: 154686900

Start: 2590757

End: 2591200

Strand: Reverse

Name: yrvI

Synonym: RBAM_024700

Alternate gene names: 154686900

Gene position: 2591200-2590757 (Counterclockwise)

Preceding gene: 154686901

Following gene: 154686898

Centisome position: 66.13

GC content: 46.62

Gene sequence:

>444_bases
ATGAAATTAGTTGTTCAGCGTGTAACAGAAGCGAGTGTGACGGTTGAGGGCGCTGTCGCCGGCCGGATCGGACCCGGTAT
TATGGCGCTTGTCGGCATCACTCATGAAGATACAGAAGAAGATGCCGCTTACTTGGCGGATAAAATCGTGAATCTTCGGA
TTTTTGATGATGAAAGCGGCAAGATGAATTTATCGCTTTTGGATACGGGCGGGGAGATTTTATCCGTTTCACAGTTTACG
CTTTACGGCGAAACGAAGAAAGGGAGACGCCCGAATTTTATGAATGCGGCTAAACCGGATCAGGCTGTGCTCCTTTATGA
AAAGTGGAACGAACTCCTTCGGGAAAAAGGAGTCAAAGTGGAAACCGGAATATTCGGAGCCATGATGGATGTTCAGCTGA
CGAATTCCGGGCCGATTACATTGATTATGGATTCTAAACAATAA

Upstream 100 bases:

>100_bases
TATTCAAAACATCAATCATCTGCACAAAGTGGTCGAGCGGATTAAGCAGATCAGAGACATCTATTCAGTCCGCCGGGTAA
TGAACTAAAAGGAGCTTGCT

Downstream 100 bases:

>100_bases
AAAAGCTGCCGTTCGGCAGCTTTTTTTTATGATTGAAAATAATGTTCCAATCCGCTTTCAATTCCGTCTGTCACTTTTTC
CTGATAAGAGCCGCTATGTA

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MKLVVQRVTEASVTVEGAVAGRIGPGIMALVGITHEDTEEDAAYLADKIVNLRIFDDESGKMNLSLLDTGGEILSVSQFT
LYGETKKGRRPNFMNAAKPDQAVLLYEKWNELLREKGVKVETGIFGAMMDVQLTNSGPITLIMDSKQ

Sequences:

>Translated_147_residues
MKLVVQRVTEASVTVEGAVAGRIGPGIMALVGITHEDTEEDAAYLADKIVNLRIFDDESGKMNLSLLDTGGEILSVSQFT
LYGETKKGRRPNFMNAAKPDQAVLLYEKWNELLREKGVKVETGIFGAMMDVQLTNSGPITLIMDSKQ
>Mature_147_residues
MKLVVQRVTEASVTVEGAVAGRIGPGIMALVGITHEDTEEDAAYLADKIVNLRIFDDESGKMNLSLLDTGGEILSVSQFT
LYGETKKGRRPNFMNAAKPDQAVLLYEKWNELLREKGVKVETGIFGAMMDVQLTNSGPITLIMDSKQ

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=148, Percent_Identity=45.945945945946, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1790320, Length=143, Percent_Identity=45.4545454545455, Blast_Score=136, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI115533292, Length=150, Percent_Identity=45.3333333333333, Blast_Score=123, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6319982, Length=150, Percent_Identity=47.3333333333333, Blast_Score=125, Evalue=3e-30,
Organism=Drosophila melanogaster, GI281361569, Length=147, Percent_Identity=41.4965986394558, Blast_Score=111, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_BACA2 (A7Z754)

Other databases:

- EMBL:   CP000560
- RefSeq:   YP_001422061.1
- ProteinModelPortal:   A7Z754
- SMR:   A7Z754
- STRING:   A7Z754
- EnsemblBacteria:   EBBACT00000005703
- GeneID:   5460660
- GenomeReviews:   CP000560_GR
- KEGG:   bay:RBAM_024700
- eggNOG:   COG1490
- GeneTree:   EBGT00050000002392
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- ProtClustDB:   PRK05273
- BioCyc:   BAMY326423:RBAM_024700-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16062; Mature: 16062

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVVQRVTEASVTVEGAVAGRIGPGIMALVGITHEDTEEDAAYLADKIVNLRIFDDESG
CCHHHEECCCCCEEEEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHEEEEEEEECCCC
KMNLSLLDTGGEILSVSQFTLYGETKKGRRPNFMNAAKPDQAVLLYEKWNELLREKGVKV
EEEEEEEECCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCEE
ETGIFGAMMDVQLTNSGPITLIMDSKQ
ECCEEEEEEEEEECCCCCEEEEECCCC
>Mature Secondary Structure
MKLVVQRVTEASVTVEGAVAGRIGPGIMALVGITHEDTEEDAAYLADKIVNLRIFDDESG
CCHHHEECCCCCEEEEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHEEEEEEEECCCC
KMNLSLLDTGGEILSVSQFTLYGETKKGRRPNFMNAAKPDQAVLLYEKWNELLREKGVKV
EEEEEEEECCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCEE
ETGIFGAMMDVQLTNSGPITLIMDSKQ
ECCEEEEEEEEEECCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA