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The map label for this gene is supH [H]

Identifier: 154686847

GI number: 154686847

Start: 2533524

End: 2534336

Strand: Reverse

Name: supH [H]

Synonym: RBAM_024170

Alternate gene names: 154686847

Gene position: 2534336-2533524 (Counterclockwise)

Preceding gene: 154686849

Following gene: 154686846

Centisome position: 64.67

GC content: 43.42

Gene sequence:

>813_bases
ATGAGTATCAAACTGATAGCGGTTGATATGGACGGAACGTTTTTGAATGATGAAATGGCATATAATAAAGAGCGTTTTAT
GAATCAGTATCGTGAATTAAAAGCGCGGGGAATTAAATTTGCCGTAGCAAGCGGAAACCAATATGCGCAGCTTACATCCT
TCTTTCCGGAAATCAAAAGTGAAATCGCTTTCATTTCTGAGAATGGCGCTTTCGTCGTGAATGCCGGAGAAGAATTATTC
GCGGGTAACATGTCTGAAGACACTATAAAAGCAGTGATCCGTGCTTTAGAGCAGTATGAGGTGAAAAACGTCATTGTCTG
CGGAAAAAAAAGCGCGTATATTCATGAAAATGTCGGTGAAGATGAATATCTGCATGCCAGTAAGTATTATTATGTGTTAA
AAAGGGTGCCGCATTTTGAAAACATCGATGATGACATTTTGAAATTTTCCATCAGCTTTCCCGCCGAACATTGTTCCGCA
CTTCTGAGCCATTTAAAAAACGCCATCGGGTCTTTCGTCACGCCTGTATCAAGCGGGCACGGTGACATAGATCTGATCAT
ACCGGGGCTTCATAAAGCAAGCGGGATTAAGCTTCTCCAGAAACAATGGGGGATAAATGCTGAAGAATGCGCGGCCTTCG
GAGACAGCGGCAATGATCTGGAAATGGTGTCCGCCGTGAAATACGGGGTCGCCATGGATAATGCGCAGGAAAGCATTAAA
CAGGCTGCCGCGCATATCACGCAATCAAACAATGAAGAAGGGGTCTTAAATGCGATTGATTCCATCCTCAAATGTGAAAA
ACCCTTTGTCTGA

Upstream 100 bases:

>100_bases
TTTACGGCGCAAAACAACTGCGGATATAATTCGTTCATACGCTTTATGCATGATCTCTTCAAGGGTCTCTGACAAAAGCG
GCCGAAAAAAGGAGGACAAT

Downstream 100 bases:

>100_bases
AAAAGACATTTTAACTGCGGAGGTGCTGAACGATGATTAAATTAGTGATTACGGATTTAGACGGCACATTTTTAAATAAT
CAAGGCGATTTTGACAGAAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MSIKLIAVDMDGTFLNDEMAYNKERFMNQYRELKARGIKFAVASGNQYAQLTSFFPEIKSEIAFISENGAFVVNAGEELF
AGNMSEDTIKAVIRALEQYEVKNVIVCGKKSAYIHENVGEDEYLHASKYYYVLKRVPHFENIDDDILKFSISFPAEHCSA
LLSHLKNAIGSFVTPVSSGHGDIDLIIPGLHKASGIKLLQKQWGINAEECAAFGDSGNDLEMVSAVKYGVAMDNAQESIK
QAAAHITQSNNEEGVLNAIDSILKCEKPFV

Sequences:

>Translated_270_residues
MSIKLIAVDMDGTFLNDEMAYNKERFMNQYRELKARGIKFAVASGNQYAQLTSFFPEIKSEIAFISENGAFVVNAGEELF
AGNMSEDTIKAVIRALEQYEVKNVIVCGKKSAYIHENVGEDEYLHASKYYYVLKRVPHFENIDDDILKFSISFPAEHCSA
LLSHLKNAIGSFVTPVSSGHGDIDLIIPGLHKASGIKLLQKQWGINAEECAAFGDSGNDLEMVSAVKYGVAMDNAQESIK
QAAAHITQSNNEEGVLNAIDSILKCEKPFV
>Mature_269_residues
SIKLIAVDMDGTFLNDEMAYNKERFMNQYRELKARGIKFAVASGNQYAQLTSFFPEIKSEIAFISENGAFVVNAGEELFA
GNMSEDTIKAVIRALEQYEVKNVIVCGKKSAYIHENVGEDEYLHASKYYYVLKRVPHFENIDDDILKFSISFPAEHCSAL
LSHLKNAIGSFVTPVSSGHGDIDLIIPGLHKASGIKLLQKQWGINAEECAAFGDSGNDLEMVSAVKYGVAMDNAQESIKQ
AAAHITQSNNEEGVLNAIDSILKCEKPFV

Specific function: Catalyzes the hydrolysis of sugar phosphate to sugar and inorganic phosphate. Has a wide substrate specificity catalyzing the hydrolysis of fructose-1-P most efficiently, but it remains uncertain if this is the real substrate in vivo [H]

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family. SupH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787043, Length=269, Percent_Identity=49.4423791821561, Blast_Score=268, Evalue=2e-73,
Organism=Escherichia coli, GI87081790, Length=269, Percent_Identity=48.6988847583643, Blast_Score=267, Evalue=7e-73,
Organism=Escherichia coli, GI2367265, Length=270, Percent_Identity=28.5185185185185, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006379
- InterPro:   IPR000150 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.23 [H]

Molecular weight: Translated: 29814; Mature: 29683

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKLIAVDMDGTFLNDEMAYNKERFMNQYRELKARGIKFAVASGNQYAQLTSFFPEIKS
CCEEEEEEECCCCEECHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHH
EIAFISENGAFVVNAGEELFAGNMSEDTIKAVIRALEQYEVKNVIVCGKKSAYIHENVGE
HEEEEECCCEEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHCEEEEECCCCCEEECCCCC
DEYLHASKYYYVLKRVPHFENIDDDILKFSISFPAEHCSALLSHLKNAIGSFVTPVSSGH
CHHHHHHHHHHHHHHCCCCCCCCHHHHEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCC
GDIDLIIPGLHKASGIKLLQKQWGINAEECAAFGDSGNDLEMVSAVKYGVAMDNAQESIK
CCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QAAAHITQSNNEEGVLNAIDSILKCEKPFV
HHHHHHHCCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SIKLIAVDMDGTFLNDEMAYNKERFMNQYRELKARGIKFAVASGNQYAQLTSFFPEIKS
CEEEEEEECCCCEECHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHH
EIAFISENGAFVVNAGEELFAGNMSEDTIKAVIRALEQYEVKNVIVCGKKSAYIHENVGE
HEEEEECCCEEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHCEEEEECCCCCEEECCCCC
DEYLHASKYYYVLKRVPHFENIDDDILKFSISFPAEHCSALLSHLKNAIGSFVTPVSSGH
CHHHHHHHHHHHHHHCCCCCCCCHHHHEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCC
GDIDLIIPGLHKASGIKLLQKQWGINAEECAAFGDSGNDLEMVSAVKYGVAMDNAQESIK
CCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QAAAHITQSNNEEGVLNAIDSILKCEKPFV
HHHHHHHCCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]