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The map label for this gene is bkdR [H]

Identifier: 154686669

GI number: 154686669

Start: 2375202

End: 2377271

Strand: Reverse

Name: bkdR [H]

Synonym: RBAM_022380

Alternate gene names: 154686669

Gene position: 2377271-2375202 (Counterclockwise)

Preceding gene: 154686671

Following gene: 154686668

Centisome position: 60.67

GC content: 48.45

Gene sequence:

>2070_bases
ATGCAGAAGGTGCTGATTATAGGTGCTGGTAAAGGAGGCACGGCGCTCCTACAGATTTTGATGAAAACAAAGCTGATCCG
GATTATTGCGGTGGTTGATCAAGATCCGGAGGCGCAAGGGCTGCAAGAAGCCCGGAGATATGGAATTGCAACCTCATCAG
ATTGGAAACCCTACATAACTGAAGATATAGATATTATCATCCATACAACAGGCGATAAAGCGGTCATGGATGAGCTGCTC
CATGAGAAAAAAGAACAAACCATCGTCATGCCGGGAAAATTGGCGTACATGGTGTTTCAGCTGATGGAGGAAAAACAGCA
GCTTATCCAAATGCTGAAGTCGCAGACGTATAAGCATGACCGGATTTTTAATTCAACGCACGACGGCATGATTTTTATAG
ACGTCAACGAAACGATCATTTTATTTAATCAGATGGCAGAAAAAATGGTCGGCCAAAAACGGGAGGATGTCATCGGCCGC
CAAATTAAAGATGTAGTGCCGAACACAAAGCTGCCGCGGATTCTGGAAACGAGAGAGCCGGAATATAACCAGAAGCAGCT
TCTCGGAAAGCACCTGCAGATTGTCACGACAAGACTGCCGATCATTGATGAAGGCGGAAAACTTCTCGGCGCGTTATGCG
TGTTTAAAGATATCACCGACGCAGTTGAACTGGCGGAAGAGGTCACGAACTTAAAACAAATCCGCACCATGCTTGAAGCG
ATTATACAATCATCAGACGAGGCCATTTCTGTCGTTGATGAAAACGGCATCGGAATGTTAATCAACAAAGCGTATACAAA
AATGACCGGGCTGTCAGAAAGCGAAGTCATCGGAAAACCCGCTTCCACCGATATCTCAGAAGGGGAGAGCATGCACCTGA
AAGTATTGGGGACAAGGCGGCCCGTGCGGGGTGTGAGAATGAAGGTCGGCCCCAATAAAAAGGATGTTATCGTAAATGTT
GCCCCCGTTATTGTGGACGGTATTTTAAAAGGTAGCGTCGGCGTCATCCACGACGTGTCAGAAATTAAAACGCTGACTGC
TGAGCTGAATCGGGCGCGCCAGATCATCCGCACGCTTGAAGCGAAATACACGTTTGACGACATTATCGGCACGAGTGAAC
AAATGCTGGTCGCCCTTGAACAGGCGAAGCTCGGGGCGAAAACGCCGGCGACGATTCTGCTGCGGGGAGAATCCGGCACA
GGAAAAGAACTTTTCGCCCACGCCATCCATAATGAAAGCGACCGAAAATACAATAAGTTCATCCGGGTCAATTGTGCCGC
CCTGTCTGAATCCCTGCTAGAATCCGAGCTTTTCGGCTATGAGGAAGGCGCGTTTACGGGCGCGAGGCGCGGGGGCAAAA
AAGGACTTTTTGAGGAAGCGAATAACGGCAGCATTTTCTTAGATGAAATCGGAGAGCTGACCCAAAGCACCCAGGCAAAG
CTGCTCAGAGTTCTGCAGGAAAAAGAAATTATCAGAGTCGGCGGCGCTAAAGCGATTTCTGTCAATGTCAGAATTATCGC
AGCGACAAACGTCAACATCGAAAAGGCCATGGCGGAAGGCGCGTTCCGTGAAGACCTGTATTACCGGATTAACCGCTATC
CGATCTCAATCCCGCCGCTTCGGCAGCGCAAAGAAGATATTGAAGCGCTGAGCATTCGGCTCATTGAAAAAATCAATCAG
GATTACGGCCGCAATGTAAAGGGGCTCACGCCGAACGCGCTGCGAGCTTTATCAGCCTACAGCTGGCCGGGAAACGTCCG
GGAGCTTGAAAATGTTCTCGGACGGGCAATGATATTTTTAGAGCCGCACATGGAACGGATCGAACAGCAGCATCTGCCTG
TTTTTGAATCAGAGCTAAATGAAAAAAACGGCACCCAAAGTGATTTTCCGGATGTGGAAGGGGAAAAGCTGTCTCAGGCT
GTTGAAAAATTTGAAGCGCACGTCATTCAAAAAACGCTTGAAAAGCATAAATTCAACCGAACCAAAACGGCAAAAGCGCT
TGGTGTCAGCATTCGGAATCTGTACTACAAAATGGACAAGTACGGCCTTGCAAATGACGGCATGCAATAA

Upstream 100 bases:

>100_bases
ATTTTGTCAAGAGATCAAAACGTGGTAACATAGGGGTTGTGCAAATTATTGCAACGGGAAATACAGGTGTGCAAATTTTT
TCATATAAAGGGGTATCGGG

Downstream 100 bases:

>100_bases
ATTGCAGAGAAAGCGCAAACAGCTGCATGCTTTCTTGAAAAAAGCCGGAATAAACCCTCCCGCACATTTGGCACGGAACT
TGCATTGTTAAAAGCGGATT

Product: BkdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 689; Mature: 689

Protein sequence:

>689_residues
MQKVLIIGAGKGGTALLQILMKTKLIRIIAVVDQDPEAQGLQEARRYGIATSSDWKPYITEDIDIIIHTTGDKAVMDELL
HEKKEQTIVMPGKLAYMVFQLMEEKQQLIQMLKSQTYKHDRIFNSTHDGMIFIDVNETIILFNQMAEKMVGQKREDVIGR
QIKDVVPNTKLPRILETREPEYNQKQLLGKHLQIVTTRLPIIDEGGKLLGALCVFKDITDAVELAEEVTNLKQIRTMLEA
IIQSSDEAISVVDENGIGMLINKAYTKMTGLSESEVIGKPASTDISEGESMHLKVLGTRRPVRGVRMKVGPNKKDVIVNV
APVIVDGILKGSVGVIHDVSEIKTLTAELNRARQIIRTLEAKYTFDDIIGTSEQMLVALEQAKLGAKTPATILLRGESGT
GKELFAHAIHNESDRKYNKFIRVNCAALSESLLESELFGYEEGAFTGARRGGKKGLFEEANNGSIFLDEIGELTQSTQAK
LLRVLQEKEIIRVGGAKAISVNVRIIAATNVNIEKAMAEGAFREDLYYRINRYPISIPPLRQRKEDIEALSIRLIEKINQ
DYGRNVKGLTPNALRALSAYSWPGNVRELENVLGRAMIFLEPHMERIEQQHLPVFESELNEKNGTQSDFPDVEGEKLSQA
VEKFEAHVIQKTLEKHKFNRTKTAKALGVSIRNLYYKMDKYGLANDGMQ

Sequences:

>Translated_689_residues
MQKVLIIGAGKGGTALLQILMKTKLIRIIAVVDQDPEAQGLQEARRYGIATSSDWKPYITEDIDIIIHTTGDKAVMDELL
HEKKEQTIVMPGKLAYMVFQLMEEKQQLIQMLKSQTYKHDRIFNSTHDGMIFIDVNETIILFNQMAEKMVGQKREDVIGR
QIKDVVPNTKLPRILETREPEYNQKQLLGKHLQIVTTRLPIIDEGGKLLGALCVFKDITDAVELAEEVTNLKQIRTMLEA
IIQSSDEAISVVDENGIGMLINKAYTKMTGLSESEVIGKPASTDISEGESMHLKVLGTRRPVRGVRMKVGPNKKDVIVNV
APVIVDGILKGSVGVIHDVSEIKTLTAELNRARQIIRTLEAKYTFDDIIGTSEQMLVALEQAKLGAKTPATILLRGESGT
GKELFAHAIHNESDRKYNKFIRVNCAALSESLLESELFGYEEGAFTGARRGGKKGLFEEANNGSIFLDEIGELTQSTQAK
LLRVLQEKEIIRVGGAKAISVNVRIIAATNVNIEKAMAEGAFREDLYYRINRYPISIPPLRQRKEDIEALSIRLIEKINQ
DYGRNVKGLTPNALRALSAYSWPGNVRELENVLGRAMIFLEPHMERIEQQHLPVFESELNEKNGTQSDFPDVEGEKLSQA
VEKFEAHVIQKTLEKHKFNRTKTAKALGVSIRNLYYKMDKYGLANDGMQ
>Mature_689_residues
MQKVLIIGAGKGGTALLQILMKTKLIRIIAVVDQDPEAQGLQEARRYGIATSSDWKPYITEDIDIIIHTTGDKAVMDELL
HEKKEQTIVMPGKLAYMVFQLMEEKQQLIQMLKSQTYKHDRIFNSTHDGMIFIDVNETIILFNQMAEKMVGQKREDVIGR
QIKDVVPNTKLPRILETREPEYNQKQLLGKHLQIVTTRLPIIDEGGKLLGALCVFKDITDAVELAEEVTNLKQIRTMLEA
IIQSSDEAISVVDENGIGMLINKAYTKMTGLSESEVIGKPASTDISEGESMHLKVLGTRRPVRGVRMKVGPNKKDVIVNV
APVIVDGILKGSVGVIHDVSEIKTLTAELNRARQIIRTLEAKYTFDDIIGTSEQMLVALEQAKLGAKTPATILLRGESGT
GKELFAHAIHNESDRKYNKFIRVNCAALSESLLESELFGYEEGAFTGARRGGKKGLFEEANNGSIFLDEIGELTQSTQAK
LLRVLQEKEIIRVGGAKAISVNVRIIAATNVNIEKAMAEGAFREDLYYRINRYPISIPPLRQRKEDIEALSIRLIEKINQ
DYGRNVKGLTPNALRALSAYSWPGNVRELENVLGRAMIFLEPHMERIEQQHLPVFESELNEKNGTQSDFPDVEGEKLSQA
VEKFEAHVIQKTLEKHKFNRTKTAKALGVSIRNLYYKMDKYGLANDGMQ

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=339, Percent_Identity=44.2477876106195, Blast_Score=272, Evalue=4e-74,
Organism=Escherichia coli, GI1789233, Length=476, Percent_Identity=34.0336134453782, Blast_Score=258, Evalue=8e-70,
Organism=Escherichia coli, GI1790437, Length=314, Percent_Identity=43.6305732484076, Blast_Score=246, Evalue=5e-66,
Organism=Escherichia coli, GI1789087, Length=235, Percent_Identity=50.6382978723404, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI87082117, Length=325, Percent_Identity=40.6153846153846, Blast_Score=237, Evalue=2e-63,
Organism=Escherichia coli, GI1788905, Length=322, Percent_Identity=41.304347826087, Blast_Score=233, Evalue=4e-62,
Organism=Escherichia coli, GI1786524, Length=334, Percent_Identity=38.9221556886228, Blast_Score=230, Evalue=3e-61,
Organism=Escherichia coli, GI87082152, Length=322, Percent_Identity=39.1304347826087, Blast_Score=216, Evalue=4e-57,
Organism=Escherichia coli, GI1790299, Length=335, Percent_Identity=37.3134328358209, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI1787583, Length=321, Percent_Identity=36.7601246105919, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI87081872, Length=332, Percent_Identity=35.2409638554217, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1789828, Length=303, Percent_Identity=34.983498349835, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI87081858, Length=508, Percent_Identity=24.8031496062992, Blast_Score=136, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR002197
- InterPro:   IPR016040
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 77173; Mature: 77173

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKVLIIGAGKGGTALLQILMKTKLIRIIAVVDQDPEAQGLQEARRYGIATSSDWKPYIT
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHCCCCCCCCCCCCC
EDIDIIIHTTGDKAVMDELLHEKKEQTIVMPGKLAYMVFQLMEEKQQLIQMLKSQTYKHD
CCCEEEEECCCCHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
RIFNSTHDGMIFIDVNETIILFNQMAEKMVGQKREDVIGRQIKDVVPNTKLPRILETREP
HCCCCCCCCEEEEECCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHCCCC
EYNQKQLLGKHLQIVTTRLPIIDEGGKLLGALCVFKDITDAVELAEEVTNLKQIRTMLEA
CCCHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIQSSDEAISVVDENGIGMLINKAYTKMTGLSESEVIGKPASTDISEGESMHLKVLGTRR
HHCCCCCEEEEEECCCCEEEHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCEEEEEEECCC
PVRGVRMKVGPNKKDVIVNVAPVIVDGILKGSVGVIHDVSEIKTLTAELNRARQIIRTLE
CCCCEEEEECCCCCCEEEEEHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHH
AKYTFDDIIGTSEQMLVALEQAKLGAKTPATILLRGESGTGKELFAHAIHNESDRKYNKF
HCCCHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCHHHHHE
IRVNCAALSESLLESELFGYEEGAFTGARRGGKKGLFEEANNGSIFLDEIGELTQSTQAK
EEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHH
LLRVLQEKEIIRVGGAKAISVNVRIIAATNVNIEKAMAEGAFREDLYYRINRYPISIPPL
HHHHHHHHHHEEECCCEEEEEEEEEEEEECCCHHHHHHHCHHHHHHHHHEECCCCCCCCH
RQRKEDIEALSIRLIEKINQDYGRNVKGLTPNALRALSAYSWPGNVRELENVLGRAMIFL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHEEEE
EPHMERIEQQHLPVFESELNEKNGTQSDFPDVEGEKLSQAVEKFEAHVIQKTLEKHKFNR
CHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
TKTAKALGVSIRNLYYKMDKYGLANDGMQ
HHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MQKVLIIGAGKGGTALLQILMKTKLIRIIAVVDQDPEAQGLQEARRYGIATSSDWKPYIT
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHCCCCCCCCCCCCC
EDIDIIIHTTGDKAVMDELLHEKKEQTIVMPGKLAYMVFQLMEEKQQLIQMLKSQTYKHD
CCCEEEEECCCCHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
RIFNSTHDGMIFIDVNETIILFNQMAEKMVGQKREDVIGRQIKDVVPNTKLPRILETREP
HCCCCCCCCEEEEECCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHCCCC
EYNQKQLLGKHLQIVTTRLPIIDEGGKLLGALCVFKDITDAVELAEEVTNLKQIRTMLEA
CCCHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIQSSDEAISVVDENGIGMLINKAYTKMTGLSESEVIGKPASTDISEGESMHLKVLGTRR
HHCCCCCEEEEEECCCCEEEHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCEEEEEEECCC
PVRGVRMKVGPNKKDVIVNVAPVIVDGILKGSVGVIHDVSEIKTLTAELNRARQIIRTLE
CCCCEEEEECCCCCCEEEEEHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHH
AKYTFDDIIGTSEQMLVALEQAKLGAKTPATILLRGESGTGKELFAHAIHNESDRKYNKF
HCCCHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCHHHHHE
IRVNCAALSESLLESELFGYEEGAFTGARRGGKKGLFEEANNGSIFLDEIGELTQSTQAK
EEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHH
LLRVLQEKEIIRVGGAKAISVNVRIIAATNVNIEKAMAEGAFREDLYYRINRYPISIPPL
HHHHHHHHHHEEECCCEEEEEEEEEEEEECCCHHHHHHHCHHHHHHHHHEECCCCCCCCH
RQRKEDIEALSIRLIEKINQDYGRNVKGLTPNALRALSAYSWPGNVRELENVLGRAMIFL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHEEEE
EPHMERIEQQHLPVFESELNEKNGTQSDFPDVEGEKLSQAVEKFEAHVIQKTLEKHKFNR
CHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
TKTAKALGVSIRNLYYKMDKYGLANDGMQ
HHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]