Click here to switch to the map view.

The map label for this gene is dsdA [H]

Identifier: 154686621

GI number: 154686621

Start: 2272366

End: 2273715

Strand: Reverse

Name: dsdA [H]

Synonym: RBAM_021900

Alternate gene names: 154686621

Gene position: 2273715-2272366 (Counterclockwise)

Preceding gene: 154686622

Following gene: 154686620

Centisome position: 58.02

GC content: 52.74

Gene sequence:

>1350_bases
ATGTCCGACCGGGATATACACAAGGCATTGATGGCAGAGCCTCTAGTCAGGCAAATGGCGGAGGCGCGTGAAGTATTTTG
GATCAATCCGCATAAAACCGATGATCCAGTAAAGCATGGCGCTGAATGGAAAAAGGAGATTGCCGAAGCGGAAGAAAGGC
TGCGCCGGTTTGCGCCTTATATCGCGTCGGCTTTTCCGGAGACGGAAGCGGAGGGAGGCCTCATTGAATCTCCGCTTGTC
TTGATTAATGAAATGAAGAAGCATCTGGAACACAGCGCCGCTCAGGCTTTCCCCGGGCGTCTGCTTTTGAAATGCGACGA
CGAACTTCCGATTTCCGGTTCCATTAAAGCGCGCGGCGGGATTTACGAAGTGCTGAAGCTTGCCGAAGATCTCGCGGTAA
AAGCGGGAATGCTCTCAGCAGACGACGATTACAGCATATTGACTGAAGAACGGTTTACCGCTTTTTTCTCAAAATACTCT
ATAGCCGTCGGCTCTACGGGCAATTTAGGCCTGAGTATCGGCATAATCGGCGCGAAGCTCGGCTTTTGTGTGACCGTTCA
TATGTCCAGTGACGCAAAGCAGTGGAAAAAGGAGCTGCTCCGGGAAAAGGGGGTTCGCGTCATCGAATATGAAGCAGACT
ACAGTCTGGCTGTCAAAGAGGGGCGCATGCAGGCGAAGCAGGACCCTTATTGTTATTTTATTGATGATGAGCATTCCCGG
GATCTGTTTTTGGGGTATGCCGTTGCGGGAAGCCGTGTGAAAAAGCAGCTCGATCAAATGAACATAAAGCCTGATGCAGA
TGAACCGCTTTTCGTTTATTTGCCATGCGGGGTCGGAGGAGGCCCGGGCGGCGTCGCGCTTGCGCTAAAGCTGATCTATG
GCGAGCATGTCCATATTTTTTTCGGTGAGCCGACGCATTCACCGTGTATGCTGTTAGGACTGTTTTCCGGCTTGCATGAC
GGAATCAGCGTGCAGGATATCGGTCTTGATAATCAAACGGCCGCCGACGGACTCGCGGTGGGAAGGCCGTCCGGACTGGC
CGGCCCTCTGATGGAACCTATACTAAGCGGTTGTTATACCGCCGATGACGGCACGCTTTTTTCGCTGCTTTATCAATTAA
GGGCGGCCGAGAATAAGAGCCTTGAACCCTCTGCACTCGCCGGACTGGCCGGAGCCGTCAAGGTCGTTCAGACCGAAGCC
GGAAACCGTTATATAAAAGAGCGGGGGCTTGAGATGGAAAATGCCGTGCACCTTGTGTGGAGCACCGGCGGAAGCATGGT
TCCGGAGGAGGAAATGGAAGAGTACAGCCGGATCGGTTCCTCATTTTTGAAAAAAATGGGCAGACAGTGA

Upstream 100 bases:

>100_bases
TGGATGAGCCTCGGGACGAAGCTGTATCAGCTTTTCCCATCGTTTACAGAAAAACTGGCCGGCCGCGCATTAAAGAAAAA
GTAACAAGGGGGAAAAAGGA

Downstream 100 bases:

>100_bases
AGCGGTTTTCCGTTACAATCTTTGTAAGCGTTTGTTTTTTTATCGGAAAGCCATACAGAGAGATTGGTGTGAATTGTGAA
AAGTAAAGAATTGAACTTAC

Product: D-serine dehydratase

Products: NA

Alternate protein names: D-serine deaminase; DSD [H]

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MSDRDIHKALMAEPLVRQMAEAREVFWINPHKTDDPVKHGAEWKKEIAEAEERLRRFAPYIASAFPETEAEGGLIESPLV
LINEMKKHLEHSAAQAFPGRLLLKCDDELPISGSIKARGGIYEVLKLAEDLAVKAGMLSADDDYSILTEERFTAFFSKYS
IAVGSTGNLGLSIGIIGAKLGFCVTVHMSSDAKQWKKELLREKGVRVIEYEADYSLAVKEGRMQAKQDPYCYFIDDEHSR
DLFLGYAVAGSRVKKQLDQMNIKPDADEPLFVYLPCGVGGGPGGVALALKLIYGEHVHIFFGEPTHSPCMLLGLFSGLHD
GISVQDIGLDNQTAADGLAVGRPSGLAGPLMEPILSGCYTADDGTLFSLLYQLRAAENKSLEPSALAGLAGAVKVVQTEA
GNRYIKERGLEMENAVHLVWSTGGSMVPEEEMEEYSRIGSSFLKKMGRQ

Sequences:

>Translated_449_residues
MSDRDIHKALMAEPLVRQMAEAREVFWINPHKTDDPVKHGAEWKKEIAEAEERLRRFAPYIASAFPETEAEGGLIESPLV
LINEMKKHLEHSAAQAFPGRLLLKCDDELPISGSIKARGGIYEVLKLAEDLAVKAGMLSADDDYSILTEERFTAFFSKYS
IAVGSTGNLGLSIGIIGAKLGFCVTVHMSSDAKQWKKELLREKGVRVIEYEADYSLAVKEGRMQAKQDPYCYFIDDEHSR
DLFLGYAVAGSRVKKQLDQMNIKPDADEPLFVYLPCGVGGGPGGVALALKLIYGEHVHIFFGEPTHSPCMLLGLFSGLHD
GISVQDIGLDNQTAADGLAVGRPSGLAGPLMEPILSGCYTADDGTLFSLLYQLRAAENKSLEPSALAGLAGAVKVVQTEA
GNRYIKERGLEMENAVHLVWSTGGSMVPEEEMEEYSRIGSSFLKKMGRQ
>Mature_448_residues
SDRDIHKALMAEPLVRQMAEAREVFWINPHKTDDPVKHGAEWKKEIAEAEERLRRFAPYIASAFPETEAEGGLIESPLVL
INEMKKHLEHSAAQAFPGRLLLKCDDELPISGSIKARGGIYEVLKLAEDLAVKAGMLSADDDYSILTEERFTAFFSKYSI
AVGSTGNLGLSIGIIGAKLGFCVTVHMSSDAKQWKKELLREKGVRVIEYEADYSLAVKEGRMQAKQDPYCYFIDDEHSRD
LFLGYAVAGSRVKKQLDQMNIKPDADEPLFVYLPCGVGGGPGGVALALKLIYGEHVHIFFGEPTHSPCMLLGLFSGLHDG
ISVQDIGLDNQTAADGLAVGRPSGLAGPLMEPILSGCYTADDGTLFSLLYQLRAAENKSLEPSALAGLAGAVKVVQTEAG
NRYIKERGLEMENAVHLVWSTGGSMVPEEEMEEYSRIGSSFLKKMGRQ

Specific function: Unknown

COG id: COG3048

COG function: function code E; D-serine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family. DsdA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788708, Length=437, Percent_Identity=57.4370709382151, Blast_Score=476, Evalue=1e-135,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011780
- InterPro:   IPR001926
- InterPro:   IPR000634 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.18 [H]

Molecular weight: Translated: 49116; Mature: 48985

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRDIHKALMAEPLVRQMAEAREVFWINPHKTDDPVKHGAEWKKEIAEAEERLRRFAPY
CCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IASAFPETEAEGGLIESPLVLINEMKKHLEHSAAQAFPGRLLLKCDDELPISGSIKARGG
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCC
IYEVLKLAEDLAVKAGMLSADDDYSILTEERFTAFFSKYSIAVGSTGNLGLSIGIIGAKL
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCEEEEEEEECE
GFCVTVHMSSDAKQWKKELLREKGVRVIEYEADYSLAVKEGRMQAKQDPYCYFIDDEHSR
EEEEEEEECCCHHHHHHHHHHHCCCEEEEEECCCEEEEHHCCCCCCCCCEEEEECCCCCC
DLFLGYAVAGSRVKKQLDQMNIKPDADEPLFVYLPCGVGGGPGGVALALKLIYGEHVHIF
CEEEEEHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCEEEEE
FGEPTHSPCMLLGLFSGLHDGISVQDIGLDNQTAADGLAVGRPSGLAGPLMEPILSGCYT
ECCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCEE
ADDGTLFSLLYQLRAAENKSLEPSALAGLAGAVKVVQTEAGNRYIKERGLEMENAVHLVW
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEECCCCHHHHHCCCCHHHCEEEEE
STGGSMVPEEEMEEYSRIGSSFLKKMGRQ
ECCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDRDIHKALMAEPLVRQMAEAREVFWINPHKTDDPVKHGAEWKKEIAEAEERLRRFAPY
CCHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IASAFPETEAEGGLIESPLVLINEMKKHLEHSAAQAFPGRLLLKCDDELPISGSIKARGG
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCC
IYEVLKLAEDLAVKAGMLSADDDYSILTEERFTAFFSKYSIAVGSTGNLGLSIGIIGAKL
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCEEEEEEEECE
GFCVTVHMSSDAKQWKKELLREKGVRVIEYEADYSLAVKEGRMQAKQDPYCYFIDDEHSR
EEEEEEEECCCHHHHHHHHHHHCCCEEEEEECCCEEEEHHCCCCCCCCCEEEEECCCCCC
DLFLGYAVAGSRVKKQLDQMNIKPDADEPLFVYLPCGVGGGPGGVALALKLIYGEHVHIF
CEEEEEHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCEEEEE
FGEPTHSPCMLLGLFSGLHDGISVQDIGLDNQTAADGLAVGRPSGLAGPLMEPILSGCYT
ECCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCEE
ADDGTLFSLLYQLRAAENKSLEPSALAGLAGAVKVVQTEAGNRYIKERGLEMENAVHLVW
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEECCCCHHHHHCCCCHHHCEEEEE
STGGSMVPEEEMEEYSRIGSSFLKKMGRQ
ECCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]