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The map label for this gene is xerD [H]

Identifier: 154686593

GI number: 154686593

Start: 2251648

End: 2252538

Strand: Reverse

Name: xerD [H]

Synonym: RBAM_021620

Alternate gene names: 154686593

Gene position: 2252538-2251648 (Counterclockwise)

Preceding gene: 154686594

Following gene: 154686592

Centisome position: 57.48

GC content: 47.25

Gene sequence:

>891_bases
GTGAAGGATCAAATTAAGGATTTCATCCATTATGTGAGGGTTGAAAGAGGGCTGTCCCAAAATACGATGATGTCCTATGA
GCGTGATCTGAAAAGTTATTCTCTCTTCTTAACTGAAACCCTTCAGATCACTTCATGGAATGATGTGACCCGTCTTCATA
TTATTCAATATTTAAAGCATATAAAGGACTCCGGGAAATCAGGCAAGACGTCTGCGAGGCATTTGGCGTCAATCCGGTCT
TTTCATCAATTTCTGTTAAGGGAAAAAGCCGCGGATAAAGATCCTTCGGTACATATTGAAACACAAAAAACAGAGCGGAC
GCTTCCGAAAGTATTGGCGCTTCACGAAGTTGAGCGGTTATTGGACACGCCTAAGCTTGACAGCCCGTTCGGCCTCAGGG
ATAAAGCCATGCTTGAACTGCTGTACGCGACCGGCATCAGGGTCAGCGAGATGATCGAGCTGAAATTATCCGACGTCCAT
TTGACGATGGGATTTGTCCGCTGCTTCGGAAAAGGGCGGAAAGAGCGGATTGTGCCGATTGGTGAAGCCGCTTCTCATGC
GATAGAAGCATACATTGAAAAAGCCAGAGGGAAATTATTAAAGAAAAACGTAACCGAAGCGCTTTTTCTGAATCATCACG
GCAGGCAGATCAGCCGTCAGGGATTCTGGAAAAACCTAAAAAAAATCGCACTTGAAGCGGGGATTAAAAAAGAGCTGACA
CCGCACACGCTCCGGCACTCCTTTGCAACGCACCTGCTCGAAAACGGGGCGGATCTGCGCGCCGTGCAGGAGATGCTCGG
ACATGCCGATATTTCCACCACGCAAATTTATACGCATGTGACGAAAACAAGGCTGAAGGACGTGTACAAACAGTATCATC
CGCGCGCTTAG

Upstream 100 bases:

>100_bases
GAAGGCTCCGCCGTCAAAGTGGCCAAAACGGAACATGAGGAGAAAGACGGCTGGTTCGGCCGATTGATCTTTTTTTACCA
AAACGGGGAGTAGATCAAGA

Downstream 100 bases:

>100_bases
GAGCCGCTGCCAGAGGGGCCGCGGCTTTTTTGCCGGATTGGCGGAATACAGAGAAGGTTCTAATTATTTGAATCGGCATT
GTCAACAAGAATGTAAACGG

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MKDQIKDFIHYVRVERGLSQNTMMSYERDLKSYSLFLTETLQITSWNDVTRLHIIQYLKHIKDSGKSGKTSARHLASIRS
FHQFLLREKAADKDPSVHIETQKTERTLPKVLALHEVERLLDTPKLDSPFGLRDKAMLELLYATGIRVSEMIELKLSDVH
LTMGFVRCFGKGRKERIVPIGEAASHAIEAYIEKARGKLLKKNVTEALFLNHHGRQISRQGFWKNLKKIALEAGIKKELT
PHTLRHSFATHLLENGADLRAVQEMLGHADISTTQIYTHVTKTRLKDVYKQYHPRA

Sequences:

>Translated_296_residues
MKDQIKDFIHYVRVERGLSQNTMMSYERDLKSYSLFLTETLQITSWNDVTRLHIIQYLKHIKDSGKSGKTSARHLASIRS
FHQFLLREKAADKDPSVHIETQKTERTLPKVLALHEVERLLDTPKLDSPFGLRDKAMLELLYATGIRVSEMIELKLSDVH
LTMGFVRCFGKGRKERIVPIGEAASHAIEAYIEKARGKLLKKNVTEALFLNHHGRQISRQGFWKNLKKIALEAGIKKELT
PHTLRHSFATHLLENGADLRAVQEMLGHADISTTQIYTHVTKTRLKDVYKQYHPRA
>Mature_296_residues
MKDQIKDFIHYVRVERGLSQNTMMSYERDLKSYSLFLTETLQITSWNDVTRLHIIQYLKHIKDSGKSGKTSARHLASIRS
FHQFLLREKAADKDPSVHIETQKTERTLPKVLALHEVERLLDTPKLDSPFGLRDKAMLELLYATGIRVSEMIELKLSDVH
LTMGFVRCFGKGRKERIVPIGEAASHAIEAYIEKARGKLLKKNVTEALFLNHHGRQISRQGFWKNLKKIALEAGIKKELT
PHTLRHSFATHLLENGADLRAVQEMLGHADISTTQIYTHVTKTRLKDVYKQYHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=297, Percent_Identity=46.1279461279461, Blast_Score=260, Evalue=7e-71,
Organism=Escherichia coli, GI1790244, Length=292, Percent_Identity=36.3013698630137, Blast_Score=195, Evalue=3e-51,
Organism=Escherichia coli, GI1790768, Length=163, Percent_Identity=30.0613496932515, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790767, Length=186, Percent_Identity=27.9569892473118, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34100; Mature: 34100

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDQIKDFIHYVRVERGLSQNTMMSYERDLKSYSLFLTETLQITSWNDVTRLHIIQYLKH
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHH
IKDSGKSGKTSARHLASIRSFHQFLLREKAADKDPSVHIETQKTERTLPKVLALHEVERL
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHH
LDTPKLDSPFGLRDKAMLELLYATGIRVSEMIELKLSDVHLTMGFVRCFGKGRKERIVPI
HCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GEAASHAIEAYIEKARGKLLKKNVTEALFLNHHGRQISRQGFWKNLKKIALEAGIKKELT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
PHTLRHSFATHLLENGADLRAVQEMLGHADISTTQIYTHVTKTRLKDVYKQYHPRA
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKDQIKDFIHYVRVERGLSQNTMMSYERDLKSYSLFLTETLQITSWNDVTRLHIIQYLKH
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHH
IKDSGKSGKTSARHLASIRSFHQFLLREKAADKDPSVHIETQKTERTLPKVLALHEVERL
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHH
LDTPKLDSPFGLRDKAMLELLYATGIRVSEMIELKLSDVHLTMGFVRCFGKGRKERIVPI
HCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GEAASHAIEAYIEKARGKLLKKNVTEALFLNHHGRQISRQGFWKNLKKIALEAGIKKELT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
PHTLRHSFATHLLENGADLRAVQEMLGHADISTTQIYTHVTKTRLKDVYKQYHPRA
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10537218; 10498718 [H]