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The map label for this gene is resA [H]

Identifier: 154686560

GI number: 154686560

Start: 2225385

End: 2225924

Strand: Reverse

Name: resA [H]

Synonym: RBAM_021290

Alternate gene names: 154686560

Gene position: 2225924-2225385 (Counterclockwise)

Preceding gene: 154686561

Following gene: 154686559

Centisome position: 56.8

GC content: 46.11

Gene sequence:

>540_bases
ATGAACAAAAAACGGCGGCGTTTATTCATTCGGACCGGCATCCTTCTCATCTTACTCTGCGCGCTCGGATATACCATCTA
TAATGCCGTATATACAAACGGTGAGCGTATATCTGAGGGGTCCAAAGCCCCGAATTTCGCGCTGAAAGATACAGAGGGCA
GACTCATAGAACTGAGTCAGTTAAAAGGAAAAGGTGTTTTTCTGAATTTCTGGGGAACGTGGTGTGAGCCGTGCAAGCAG
GAATTTCCCTATATGGAGAATCAATACAAGCATTTTAAAGACCTCGGTGTCGAGGTGGTTGCGGTAAATGTCGGCGAATC
AAAAATTGCAGTACATAATTTTATGAAAACATACGGCGTCAATTTCCCGGTTGCGCTCGATACTGACCGGCAAGTGCTGG
ACGCGTACGGCGTATCACCTATTCCGACGACATTTTTGATCAATCCCGACGGAAAAGTCGTGAAAGTGGTGACCGGCACG
ATGACAGAACGCATGGTTCATGACTATATGAATTTAATTAAGCCGGAGGCGTCTTCATGA

Upstream 100 bases:

>100_bases
TAAAAACGCTTTCTAATTTTCACATAACCTTCAAAAATTACAAAACGTGTTGATGATATAATTGAATGGATTTGCAGGCA
GGGGAGGGGAGCAGTGTACA

Downstream 100 bases:

>100_bases
AAAAGGTCAAATGTGAATGCGGGCACGTGAATCCAGCCGGGACGGTTTTGTGCGAGTCGTGCGGGAAGCCGCTTGATGAT
CAAAAATCGCCGCTTGCCGA

Product: thiol-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MNKKRRRLFIRTGILLILLCALGYTIYNAVYTNGERISEGSKAPNFALKDTEGRLIELSQLKGKGVFLNFWGTWCEPCKQ
EFPYMENQYKHFKDLGVEVVAVNVGESKIAVHNFMKTYGVNFPVALDTDRQVLDAYGVSPIPTTFLINPDGKVVKVVTGT
MTERMVHDYMNLIKPEASS

Sequences:

>Translated_179_residues
MNKKRRRLFIRTGILLILLCALGYTIYNAVYTNGERISEGSKAPNFALKDTEGRLIELSQLKGKGVFLNFWGTWCEPCKQ
EFPYMENQYKHFKDLGVEVVAVNVGESKIAVHNFMKTYGVNFPVALDTDRQVLDAYGVSPIPTTFLINPDGKVVKVVTGT
MTERMVHDYMNLIKPEASS
>Mature_179_residues
MNKKRRRLFIRTGILLILLCALGYTIYNAVYTNGERISEGSKAPNFALKDTEGRLIELSQLKGKGVFLNFWGTWCEPCKQ
EFPYMENQYKHFKDLGVEVVAVNVGESKIAVHNFMKTYGVNFPVALDTDRQVLDAYGVSPIPTTFLINPDGKVVKVVTGT
MTERMVHDYMNLIKPEASS

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: NA

Molecular weight: Translated: 20232; Mature: 20232

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKRRRLFIRTGILLILLCALGYTIYNAVYTNGERISEGSKAPNFALKDTEGRLIELSQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCEEEEEE
LKGKGVFLNFWGTWCEPCKQEFPYMENQYKHFKDLGVEVVAVNVGESKIAVHNFMKTYGV
CCCCEEEEEECCHHHHHHHHHCCCHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHCC
NFPVALDTDRQVLDAYGVSPIPTTFLINPDGKVVKVVTGTMTERMVHDYMNLIKPEASS
CCCEEECCCHHHHHHCCCCCCCEEEEECCCCCEEEEEECHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNKKRRRLFIRTGILLILLCALGYTIYNAVYTNGERISEGSKAPNFALKDTEGRLIELSQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCEEEEEE
LKGKGVFLNFWGTWCEPCKQEFPYMENQYKHFKDLGVEVVAVNVGESKIAVHNFMKTYGV
CCCCEEEEEECCHHHHHHHHHCCCHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHCC
NFPVALDTDRQVLDAYGVSPIPTTFLINPDGKVVKVVTGTMTERMVHDYMNLIKPEASS
CCCEEECCCHHHHHHCCCCCCCEEEEECCCCCEEEEEECHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 12637552 [H]